Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 164 (11 Dec 2019)
Sequence version 4 (12 Sep 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Complement C1q tumor necrosis factor-related protein 6

Gene

C1QTNF6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C1QTNF6
Synonyms:CTRP6
ORF Names:UNQ581/PRO1151
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000133466.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14343 C1QTNF6

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614910 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BXI9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
114904

Open Targets

More...
OpenTargetsi
ENSG00000133466

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25633

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BXI9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C1QTNF6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
206729927

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 461 PublicationAdd BLAST46
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000353847 – 278Complement C1q tumor necrosis factor-related protein 6Add BLAST232

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi91N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BXI9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BXI9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BXI9

PeptideAtlas

More...
PeptideAtlasi
Q9BXI9

PRoteomics IDEntifications database

More...
PRIDEi
Q9BXI9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79429 [Q9BXI9-1]
79430 [Q9BXI9-2]
79431 [Q9BXI9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BXI9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BXI9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000133466 Expressed in 104 organ(s), highest expression level in decidua

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BXI9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BXI9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA002042

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
O437653EBI-10301084,EBI-347996

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125393, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BXI9, 11 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000338812

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BXI9 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini97 – 138Collagen-likeAdd BLAST42
Domaini139 – 259C1qPROSITE-ProRule annotationAdd BLAST121

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKX5 Eukaryota
ENOG410XQIM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160396

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BXI9

KEGG Orthology (KO)

More...
KOi
K19470

Identification of Orthologs from Complete Genome Data

More...
OMAi
HFDMAAG

Database of Orthologous Groups

More...
OrthoDBi
1136568at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BXI9

TreeFam database of animal gene trees

More...
TreeFami
TF329591

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001073 C1q_dom
IPR008160 Collagen
IPR008983 Tumour_necrosis_fac-like_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00386 C1q, 1 hit
PF01391 Collagen, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00007 COMPLEMNTC1Q

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00110 C1Q, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49842 SSF49842, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50871 C1Q, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BXI9-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQWLRVRESP GEATGHRVTM GTAALGPVWA ALLLFLLMCE IPMVELTFDR
60 70 80 90 100
AVASGCQRCC DSEDPLDPAH VSSASSSGRP HALPEIRPYI NITILKGDKG
110 120 130 140 150
DPGPMGLPGY MGREGPQGEP GPQGSKGDKG EMGSPGAPCQ KRFFAFSVGR
160 170 180 190 200
KTALHSGEDF QTLLFERVFV NLDGCFDMAT GQFAAPLRGI YFFSLNVHSW
210 220 230 240 250
NYKETYVHIM HNQKEAVILY AQPSERSIMQ SQSVMLDLAY GDRVWVRLFK
260 270
RQRENAIYSN DFDTYITFSG HLIKAEDD
Length:278
Mass (Da):30,861
Last modified:September 12, 2018 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i27A82CA863F23D47
GO
Isoform 2 (identifier: Q9BXI9-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-19: Missing.

Show »
Length:259
Mass (Da):28,669
Checksum:i876DD0F84D217C9A
GO
Isoform 3 (identifier: Q9BXI9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-147: MQWLRVRESP...PCQKRFFAFS → MSVGTSLEQAQMSTLTCPLFIPT

Show »
Length:154
Mass (Da):17,720
Checksum:iE2A73F65529ED7A1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WC87F8WC87_HUMAN
Complement C1q tumor necrosis facto...
C1QTNF6
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04662421G → V2 PublicationsCorresponds to variant dbSNP:rs229527Ensembl.1
Natural variantiVAR_04662542P → R1 PublicationCorresponds to variant dbSNP:rs229526Ensembl.1
Natural variantiVAR_04662655G → D. Corresponds to variant dbSNP:rs7290488Ensembl.1
Natural variantiVAR_046627138P → L. Corresponds to variant dbSNP:rs17812699Ensembl.1
Natural variantiVAR_046628226R → H. Corresponds to variant dbSNP:rs17812681Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0597651 – 147MQWLR…FFAFS → MSVGTSLEQAQMSTLTCPLF IPT in isoform 3. Add BLAST147
Alternative sequenceiVSP_0597661 – 19Missing in isoform 2. Add BLAST19

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF329842 mRNA Translation: AAK17966.1
AY358374 mRNA Translation: AAQ88740.1
AK128125 mRNA Translation: BAC87283.1
Z82188 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60145.1
BC020551 mRNA Translation: AAH20551.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13943.1 [Q9BXI9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_114116.3, NM_031910.3 [Q9BXI9-2]
NP_872292.1, NM_182486.1 [Q9BXI9-2]
XP_011528159.1, XM_011529857.1 [Q9BXI9-1]
XP_016884059.1, XM_017028570.1
XP_016884060.1, XM_017028571.1
XP_016884061.1, XM_017028572.1
XP_016884062.1, XM_017028573.1
XP_016884063.1, XM_017028574.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000337843; ENSP00000338812; ENSG00000133466 [Q9BXI9-2]
ENST00000397110; ENSP00000380299; ENSG00000133466 [Q9BXI9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
114904

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:114904

UCSC genome browser

More...
UCSCi
uc003aqx.2 human [Q9BXI9-2]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329842 mRNA Translation: AAK17966.1
AY358374 mRNA Translation: AAQ88740.1
AK128125 mRNA Translation: BAC87283.1
Z82188 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60145.1
BC020551 mRNA Translation: AAH20551.1
CCDSiCCDS13943.1 [Q9BXI9-2]
RefSeqiNP_114116.3, NM_031910.3 [Q9BXI9-2]
NP_872292.1, NM_182486.1 [Q9BXI9-2]
XP_011528159.1, XM_011529857.1 [Q9BXI9-1]
XP_016884059.1, XM_017028570.1
XP_016884060.1, XM_017028571.1
XP_016884061.1, XM_017028572.1
XP_016884062.1, XM_017028573.1
XP_016884063.1, XM_017028574.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125393, 9 interactors
IntActiQ9BXI9, 11 interactors
STRINGi9606.ENSP00000338812

PTM databases

iPTMnetiQ9BXI9
PhosphoSitePlusiQ9BXI9

Polymorphism and mutation databases

BioMutaiC1QTNF6
DMDMi206729927

Proteomic databases

jPOSTiQ9BXI9
MassIVEiQ9BXI9
PaxDbiQ9BXI9
PeptideAtlasiQ9BXI9
PRIDEiQ9BXI9
ProteomicsDBi79429 [Q9BXI9-1]
79430 [Q9BXI9-2]
79431 [Q9BXI9-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
114904

Genome annotation databases

EnsembliENST00000337843; ENSP00000338812; ENSG00000133466 [Q9BXI9-2]
ENST00000397110; ENSP00000380299; ENSG00000133466 [Q9BXI9-2]
GeneIDi114904
KEGGihsa:114904
UCSCiuc003aqx.2 human [Q9BXI9-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
114904
DisGeNETi114904
EuPathDBiHostDB:ENSG00000133466.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C1QTNF6
HGNCiHGNC:14343 C1QTNF6
HPAiHPA002042
MIMi614910 gene
neXtProtiNX_Q9BXI9
OpenTargetsiENSG00000133466
PharmGKBiPA25633

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKX5 Eukaryota
ENOG410XQIM LUCA
GeneTreeiENSGT00940000160396
InParanoidiQ9BXI9
KOiK19470
OMAiHFDMAAG
OrthoDBi1136568at2759
PhylomeDBiQ9BXI9
TreeFamiTF329591

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C1QTNF6 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
114904
PharosiQ9BXI9 Tbio

Protein Ontology

More...
PROi
PR:Q9BXI9
RNActiQ9BXI9 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000133466 Expressed in 104 organ(s), highest expression level in decidua
ExpressionAtlasiQ9BXI9 baseline and differential
GenevisibleiQ9BXI9 HS

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR001073 C1q_dom
IPR008160 Collagen
IPR008983 Tumour_necrosis_fac-like_dom
PfamiView protein in Pfam
PF00386 C1q, 1 hit
PF01391 Collagen, 1 hit
PRINTSiPR00007 COMPLEMNTC1Q
SMARTiView protein in SMART
SM00110 C1Q, 1 hit
SUPFAMiSSF49842 SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS50871 C1Q, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC1QT6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BXI9
Secondary accession number(s): Q5H9G8, Q6ZRM7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: September 12, 2018
Last modified: December 11, 2019
This is version 164 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again