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Entry version 138 (11 Dec 2019)
Sequence version 1 (01 Jun 2001)
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Protein

Protein LSM14 homolog B

Gene

LSM14B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in control of mRNA translation.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Ribonucleoprotein
Biological processTranslation regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein LSM14 homolog B
Alternative name(s):
Protein FAM61B
RNA-associated protein 55B
Short name:
hRAP55B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LSM14B
Synonyms:C20orf40, FAM61B, RAP55B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000149657.19

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15887 LSM14B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BX40

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000149657

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25754

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BX40 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LSM14B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
71151896

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001870932 – 385Protein LSM14 homolog BAdd BLAST384

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei106PhosphoserineCombined sources1
Modified residuei115PhosphoserineCombined sources1
Modified residuei154PhosphoserineCombined sources1
Modified residuei165PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki248Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei329PhosphoserineCombined sources1
Modified residuei349PhosphoserineCombined sources1
Modified residuei351Omega-N-methylarginineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BX40

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BX40

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BX40

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BX40

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BX40

PeptideAtlas

More...
PeptideAtlasi
Q9BX40

PRoteomics IDEntifications database

More...
PRIDEi
Q9BX40

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79344 [Q9BX40-1]
79345 [Q9BX40-2]
79346 [Q9BX40-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BX40

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BX40

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000149657 Expressed in 193 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BX40 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BX40 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041274
HPA061189

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a ribonucleoprotein (RNP) complex.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127252, 32 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BX40, 27 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000279068

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BX40 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BX40

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini241 – 277DFDFPROSITE-ProRule annotationAdd BLAST37

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi310 – 326FFD boxAdd BLAST17
Motifi330 – 350TFG boxAdd BLAST21

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LSM14 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1073 Eukaryota
ENOG41122RA LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156010

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231251

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BX40

KEGG Orthology (KO)

More...
KOi
K18749

Identification of Orthologs from Complete Genome Data

More...
OMAi
KCFFDNI

Database of Orthologous Groups

More...
OrthoDBi
1569369at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BX40

TreeFam database of animal gene trees

More...
TreeFami
TF313514

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01736 LSm14_N, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025762 DFDF
IPR019050 FDF_dom
IPR025761 FFD_box
IPR025609 Lsm14-like_N
IPR010920 LSM_dom_sf
IPR025768 TFG_box

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09532 FDF, 1 hit
PF12701 LSM14, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01199 FDF, 1 hit
SM01271 LSM14, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50182 SSF50182, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51512 DFDF, 1 hit
PS51513 FFD, 1 hit
PS51536 TFG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BX40-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGSSGTPYL GSKISLISKA QIRYEGILYT IDTDNSTVAL AKVRSFGTED
60 70 80 90 100
RPTDRPAPPR EEIYEYIIFR GSDIKDITVC EPPKAQHTLP QDPAIVQSSL
110 120 130 140 150
GSASASPFQP HVPYSPFRGM APYGPLAASS LLSQQYAASL GLGAGFPSIP
160 170 180 190 200
VGKSPMVEQA VQTGSADNLN AKKLLPGKGT TGTQLNGRQA QPSSKTASDV
210 220 230 240 250
VQPAAVQAQG QVNDENRRPQ RRRSGNRRTR NRSRGQNRPT NVKENTIKFE
260 270 280 290 300
GDFDFESANA QFNREELDKE FKKKLNFKDD KAEKGEEKDL AVVTQSAEAP
310 320 330 340 350
AEEDLLGPNC YYDKSKSFFD NISSELKTSS RRTTWAEERK LNTETFGVSG
360 370 380
RFLRGRSSRG GFRGGRGNGT TRRNPTSHRA GTGRV
Length:385
Mass (Da):42,071
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9F1216A57330EE32
GO
Isoform 2 (identifier: Q9BX40-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     143-220: GAGFPSIPVG...QVNDENRRPQ → EKLVSPPASA...VADHLPSPCS

Show »
Length:385
Mass (Da):42,021
Checksum:i1026731ADECB5A43
GO
Isoform 3 (identifier: Q9BX40-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-44: Missing.
     45-142: SFGTEDRPTD...SQQYAASLGL → MAPYGPLAAS...GTLEREEMER
     274-283: KLNFKDDKAE → RPILLLVFWT
     284-385: Missing.

Show »
Length:239
Mass (Da):26,019
Checksum:i8EB2347F1DE7AEEF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5TBP9Q5TBP9_HUMAN
Protein LSM14 homolog B
LSM14B
248Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5TBQ0Q5TBQ0_HUMAN
Protein LSM14 homolog B
LSM14B
296Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5TBQ1Q5TBQ1_HUMAN
Protein LSM14 homolog B
LSM14B
223Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DFV2A0A0C4DFV2_HUMAN
Protein LSM14 homolog B
LSM14B
221Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti66Y → N in BX354437 (Ref. 4) Curated1
Sequence conflicti87H → N in BX354437 (Ref. 4) Curated1
Sequence conflicti114Y → N in BX354437 (Ref. 4) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0146581 – 44Missing in isoform 3. 1 PublicationAdd BLAST44
Alternative sequenceiVSP_01465945 – 142SFGTE…ASLGL → MAPYGPLAASSLLSQQYAAS LGLEKLVSPPASAAASSPSS SPSPQPVSELDLSSEPQQLT AKGCLFCFRSLFTYTQSHIV LFRVPTGPGTLEREEMER in isoform 3. 1 PublicationAdd BLAST98
Alternative sequenceiVSP_014660143 – 220GAGFP…NRRPQ → EKLVSPPASAAASSPSSSPS PQPVSELDLSSEPQQLTAKG NSSLGELHAVLQTILRARGK AADRMTVAVADHLPSPCS in isoform 2. 1 PublicationAdd BLAST78
Alternative sequenceiVSP_014661274 – 283KLNFKDDKAE → RPILLLVFWT in isoform 3. 1 Publication10
Alternative sequenceiVSP_014662284 – 385Missing in isoform 3. 1 PublicationAdd BLAST102

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK058202 mRNA Translation: BAB71714.1
AL137077 Genomic DNA No translation available.
BC057387 mRNA Translation: AAH57387.1
BX354437 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46626.1 [Q9BX40-1]

NCBI Reference Sequences

More...
RefSeqi
NP_653304.2, NM_144703.2 [Q9BX40-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000279068; ENSP00000279068; ENSG00000149657 [Q9BX40-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
149986

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:149986

UCSC genome browser

More...
UCSCi
uc002ybt.3 human [Q9BX40-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058202 mRNA Translation: BAB71714.1
AL137077 Genomic DNA No translation available.
BC057387 mRNA Translation: AAH57387.1
BX354437 mRNA No translation available.
CCDSiCCDS46626.1 [Q9BX40-1]
RefSeqiNP_653304.2, NM_144703.2 [Q9BX40-1]

3D structure databases

SMRiQ9BX40
ModBaseiSearch...

Protein-protein interaction databases

BioGridi127252, 32 interactors
IntActiQ9BX40, 27 interactors
STRINGi9606.ENSP00000279068

PTM databases

iPTMnetiQ9BX40
PhosphoSitePlusiQ9BX40

Polymorphism and mutation databases

BioMutaiLSM14B
DMDMi71151896

Proteomic databases

EPDiQ9BX40
jPOSTiQ9BX40
MassIVEiQ9BX40
MaxQBiQ9BX40
PaxDbiQ9BX40
PeptideAtlasiQ9BX40
PRIDEiQ9BX40
ProteomicsDBi79344 [Q9BX40-1]
79345 [Q9BX40-2]
79346 [Q9BX40-3]

Genome annotation databases

EnsembliENST00000279068; ENSP00000279068; ENSG00000149657 [Q9BX40-1]
GeneIDi149986
KEGGihsa:149986
UCSCiuc002ybt.3 human [Q9BX40-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
149986
EuPathDBiHostDB:ENSG00000149657.19

GeneCards: human genes, protein and diseases

More...
GeneCardsi
LSM14B
HGNCiHGNC:15887 LSM14B
HPAiHPA041274
HPA061189
neXtProtiNX_Q9BX40
OpenTargetsiENSG00000149657
PharmGKBiPA25754

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1073 Eukaryota
ENOG41122RA LUCA
GeneTreeiENSGT00940000156010
HOGENOMiHOG000231251
InParanoidiQ9BX40
KOiK18749
OMAiKCFFDNI
OrthoDBi1569369at2759
PhylomeDBiQ9BX40
TreeFamiTF313514

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
LSM14B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
149986
PharosiQ9BX40 Tdark

Protein Ontology

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PROi
PR:Q9BX40
RNActiQ9BX40 protein

Gene expression databases

BgeeiENSG00000149657 Expressed in 193 organ(s), highest expression level in sperm
ExpressionAtlasiQ9BX40 baseline and differential
GenevisibleiQ9BX40 HS

Family and domain databases

CDDicd01736 LSm14_N, 1 hit
InterProiView protein in InterPro
IPR025762 DFDF
IPR019050 FDF_dom
IPR025761 FFD_box
IPR025609 Lsm14-like_N
IPR010920 LSM_dom_sf
IPR025768 TFG_box
PfamiView protein in Pfam
PF09532 FDF, 1 hit
PF12701 LSM14, 1 hit
SMARTiView protein in SMART
SM01199 FDF, 1 hit
SM01271 LSM14, 1 hit
SUPFAMiSSF50182 SSF50182, 1 hit
PROSITEiView protein in PROSITE
PS51512 DFDF, 1 hit
PS51513 FFD, 1 hit
PS51536 TFG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLS14B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BX40
Secondary accession number(s): Q6PFW8, Q96LH8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: June 1, 2001
Last modified: December 11, 2019
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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