UniProtKB - Q9BVV6 (TALD3_HUMAN)
Protein
Protein TALPID3
Gene
KIAA0586
Organism
Homo sapiens (Human)
Status
Functioni
Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (PubMed:24421332). Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (By similarity).By similarity1 Publication
GO - Biological processi
- cilium assembly Source: MGI
- regulation of establishment of protein localization Source: MGI
- smoothened signaling pathway Source: UniProtKB
Keywordsi
Biological process | Cilium biogenesis/degradation |
Enzyme and pathway databases
PathwayCommonsi | Q9BVV6 |
Names & Taxonomyi
Protein namesi | Recommended name: Protein TALPID3 |
Gene namesi | Name:KIAA0586 Synonyms:TALPID3 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000100578.14 |
HGNCi | HGNC:19960, KIAA0586 |
MIMi | 610178, gene |
neXtProti | NX_Q9BVV6 |
Subcellular locationi
Cytoskeleton
- centrosome 1 Publication
- centriole 2 Publications
- cilium basal body 1 Publication
Other locations
- Photoreceptor inner segment 1 Publication
Note: Forms a ring-like structure at the extreme distal end of both mother and daughter centrioles (PubMed:24421332). In photoreceptor cells localized to the joint between the inner and outer segments, specifically localized at the mother centriole (basal body) and the adjacent centriole as well as between the two centrioles but not in the connecting cilium (PubMed:26386247).2 Publications
Cytoskeleton
- centriole Source: GO_Central
- centrosome Source: UniProtKB
- ciliary basal body Source: MGI
Other locations
- cytoplasm Source: UniProtKB-KW
- photoreceptor inner segment Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell projection, Cytoplasm, CytoskeletonPathology & Biotechi
Involvement in diseasei
Joubert syndrome 23 (JBTS23)5 Publications
The disease is caused by mutations affecting the gene represented in this entry. Some patients with biallelic KIAA0586 mutations manifest a disease phenotype with features of Joubert syndrome and additional findings of a small thorax and respiratory problems consistent with Jeune syndrome (Joubert-Jeune ciliopathy).1 Publication
Disease descriptionA mild form of Joubert syndrome, a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy, renal disease, liver fibrosis, and polydactyly.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_076328 | 403 | R → K in JBTS23; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs772739103Ensembl. | 1 | |
Natural variantiVAR_074596 | 566 | D → V in JBTS23. 1 Publication | 1 |
Short-rib thoracic dysplasia 14 with polydactyly (SRTD14)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of short-rib thoracic dysplasia, a group of autosomal recessive ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a 'trident' appearance of the acetabular roof. Polydactyly is variably present. Non-skeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of the disease are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life. Disease spectrum encompasses Ellis-van Creveld syndrome, asphyxiating thoracic dystrophy (Jeune syndrome), Mainzer-Saldino syndrome, and short rib-polydactyly syndrome.
Related information in OMIMKeywords - Diseasei
Ciliopathy, Disease mutation, Joubert syndromeOrganism-specific databases
DisGeNETi | 9786 |
GeneReviewsi | KIAA0586 |
MalaCardsi | KIAA0586 |
MIMi | 616490, phenotype 616546, phenotype |
OpenTargetsi | ENSG00000100578 |
Orphaneti | 475, Joubert syndrome 397715, Joubert syndrome with Jeune asphyxiating thoracic dystrophy |
PharmGKBi | PA134992213 |
Miscellaneous databases
Pharosi | Q9BVV6, Tbio |
Polymorphism and mutation databases
BioMutai | KIAA0586 |
DMDMi | 327478601 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050766 | 1 – 1533 | Protein TALPID3Add BLAST | 1533 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 406 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1042 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1046 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1050 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1063 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1066 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | Q9BVV6 |
MassIVEi | Q9BVV6 |
MaxQBi | Q9BVV6 |
PeptideAtlasi | Q9BVV6 |
PRIDEi | Q9BVV6 |
ProteomicsDBi | 18876 79236 [Q9BVV6-1] 79237 [Q9BVV6-2] |
PTM databases
iPTMneti | Q9BVV6 |
PhosphoSitePlusi | Q9BVV6 |
Expressioni
Tissue specificityi
Ubiquitously expressed (PubMed:26386044). Expressed in photoreceptor cells (at protein level) (PubMed:26386247).2 Publications
Developmental stagei
Expressed as early as 6 weeks of gestation (Carnegie stage 16). Ubiquitously expressed during fetal development and postnatally in all adult tissues tested.1 Publication
Gene expression databases
Bgeei | ENSG00000100578, Expressed in testis and 205 other tissues |
ExpressionAtlasi | Q9BVV6, baseline and differential |
Genevisiblei | Q9BVV6, HS |
Organism-specific databases
HPAi | ENSG00000100578, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with CCP110, CEP290, CEP97, KIF24.
1 PublicationProtein-protein interaction databases
BioGRIDi | 115130, 16 interactors |
IntActi | Q9BVV6, 8 interactors |
MINTi | Q9BVV6 |
STRINGi | 9606.ENSP00000346359 |
Miscellaneous databases
RNActi | Q9BVV6, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 467 – 554 | Required for centrosomal localizationBy similarityAdd BLAST | 88 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 182 – 223 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 467 – 501 | Sequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 247 – 250 | Poly-Gln | 4 | |
Compositional biasi | 1180 – 1187 | Poly-Pro | 8 |
Sequence similaritiesi
Belongs to the TALPID3 family.Curated
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG502QUXJ, Eukaryota |
GeneTreei | ENSGT00390000012397 |
InParanoidi | Q9BVV6 |
OMAi | HLPARVC |
OrthoDBi | 66287at2759 |
PhylomeDBi | Q9BVV6 |
TreeFami | TF332939 |
Family and domain databases
InterProi | View protein in InterPro IPR029246, TALPID3 |
PANTHERi | PTHR15721, PTHR15721, 1 hit |
Pfami | View protein in Pfam PF15324, TALPID3, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 12 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q9BVV6-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MPVKRLREVV SQNHGDHLVL LKDELPCVPP ALSANKRLPV GTGTSLNGTS
60 70 80 90 100
RGSSDLTSAR NCYQPLLENP MVSESDFSKD VAVQVLPLDK IEENNKQKAN
110 120 130 140 150
DIFISQYTMG QKDALRTVLK QKAQSMPVFK EVKVHLLEDA GIEKDAVTQE
160 170 180 190 200
TRISPSGIDS ATTVAAATAA AIATAAPLIK VQSDLEAKVN SVTELLSKLQ
210 220 230 240 250
ETDKHLQRVT EQQTSIQRKQ EKLHCHDHEK QMNVFMEQHI RHLEKLQQQQ
260 270 280 290 300
IDIQTHFISA ALKTSSFQPV SMPSSRAVEK YSVKPEHPNL GSCNPSLYNT
310 320 330 340 350
FASKQAPLKE VEDTSFDKQK SPLETPAPRR FAPVPVSRDD ELSKRENLLE
360 370 380 390 400
EKENMEVSCH RGNVRLLEQI LNNNDSLTRK SESSNTTSLT RSKIGWTPEK
410 420 430 440 450
TNRFPSCEEL ETTKVTMQKS DDVLHDLGQK EKETNSMVQP KESLSMLKLP
460 470 480 490 500
DLPQNSVKLQ TTNTTRSVLK DAEKILRGVQ NNKKVLEENL EAIIRAKDGA
510 520 530 540 550
AMYSLINALS TNREMSEKIR IRKTVDEWIK TISAEIQDEL SRTDYEQKRF
560 570 580 590 600
DQKNQRTKKG QNMTKDIRTN TQDKTVNKSV IPRKHSQKQI EEHFRNLPMR
610 620 630 640 650
GMPASSLQKE RKEGLLKATT VIQDEDYMLQ VYGKPVYQGH RSTLKKGPYL
660 670 680 690 700
RFNSPSPKSR PQRPKVIERV KGTKVKSIRT QTDFYATKPK KMDSKMKHSV
710 720 730 740 750
PVLPHGDQQY LFSPSREMPT FSGTLEGHLI PMAILLGQTQ SNSDTMPPAG
760 770 780 790 800
VIVSKPHPVT VTTSIPPSSR KVETGVKKPN IAIVEMKSEK KDPPQLTVQV
810 820 830 840 850
LPSVDIDSIS NSSADVLSPL SSPKEASLPP VQTWIKTPEI MKVDEEEVKF
860 870 880 890 900
PGTNFDEIID VIQEEEKCDE IPDSEPILEF NRSVKADSTK YNGPPFPPVA
910 920 930 940 950
STFQPTADIL DKVIERKETL ENSLIQWVEQ EIMSRIISGL FPVQQQIAPS
960 970 980 990 1000
ISVSVSETSE PLTSDIVEGT SSGALQLFVD AGVPVNSNVI KHFVNEALAE
1010 1020 1030 1040 1050
TIAVMLGDRE AKKQGPVATG VSGDASTNET YLPARVCTPL PTPQPTPPCS
1060 1070 1080 1090 1100
PSSPAKECVL VKTPDSSPCD SDHDMAFPVK EICAEKGDDM PAIMLVNTPT
1110 1120 1130 1140 1150
VTPTTTPPPA AAVFTPTLSD ISIDKLKVSS PELPKPWGDG DLPLEEENPN
1160 1170 1180 1190 1200
SPQEELHPRA IVMSVAKDEE PESMDFPAQP PPPEPVPFMP FPAGTKAPSP
1210 1220 1230 1240 1250
SQMPGSDSST LESTLSVTVT ETETLDKPIS EGEILFSCGQ KLAPKILEDI
1260 1270 1280 1290 1300
GLYLTNLNDS LSSTLHDAVE MEDDPPSEGQ VIRMSHKKFH ADAILSFAKQ
1310 1320 1330 1340 1350
NQESAVSQQA VYHSEDLENS VGELSEGQRP QLTAAAENIL MGHSLYMQPP
1360 1370 1380 1390 1400
VTNTQSLDQQ CDPKPLSRQF DTVSGSIYED SCASHGPMSL GELELEPNSK
1410 1420 1430 1440 1450
LVLPTTLLTA QENDVNLPVA AEDFSQYQLK QNQDVKQVEH KPSQSYLRVR
1460 1470 1480 1490 1500
NKSDIAPSQQ QVSPGDMDRT QIELNPYLTC VFSGGKAVPL SASQMPPAKM
1510 1520 1530
SVMLPSVNLE DCSQSLSLST MQEDMESSGA DTF
Computationally mapped potential isoform sequencesi
There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A087WYM5 | A0A087WYM5_HUMAN | Protein TALPID3 | KIAA0586 | 1,463 | Annotation score: | ||
A0A494C0M8 | A0A494C0M8_HUMAN | Protein TALPID3 | KIAA0586 | 1,521 | Annotation score: | ||
A0A494C075 | A0A494C075_HUMAN | Protein TALPID3 | KIAA0586 | 958 | Annotation score: | ||
A0A494C0Z1 | A0A494C0Z1_HUMAN | Protein TALPID3 | KIAA0586 | 570 | Annotation score: | ||
H0YJF0 | H0YJF0_HUMAN | Protein TALPID3 | KIAA0586 | 208 | Annotation score: | ||
A0A494C058 | A0A494C058_HUMAN | Protein TALPID3 | KIAA0586 | 854 | Annotation score: | ||
A0A494C1C3 | A0A494C1C3_HUMAN | Protein TALPID3 | KIAA0586 | 764 | Annotation score: | ||
A0A494C133 | A0A494C133_HUMAN | Protein TALPID3 | KIAA0586 | 254 | Annotation score: | ||
G3V2T5 | G3V2T5_HUMAN | Protein TALPID3 | KIAA0586 | 234 | Annotation score: | ||
G3V4J0 | G3V4J0_HUMAN | Protein TALPID3 | KIAA0586 | 132 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
The sequence BAA25512 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Sequence conflicti | 1041 | P → A in BAA25512 (PubMed:9628581).Curated | 1 | ||
Sequence conflicti | 1041 | P → A in BAG64028 (PubMed:14702039).Curated | 1 | ||
Sequence conflicti | 1041 | P → A in EAW80740 (Ref. 5) Curated | 1 | ||
Sequence conflicti | 1041 | P → A in AAH66647 (PubMed:15489334).Curated | 1 | ||
Isoform 3 (identifier: Q9BVV6-3) | |||||
Sequence conflicti | 1568 | L → P in BAG64028 (PubMed:14702039).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_076328 | 403 | R → K in JBTS23; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs772739103Ensembl. | 1 | |
Natural variantiVAR_074596 | 566 | D → V in JBTS23. 1 Publication | 1 | |
Natural variantiVAR_069108 | 828 | L → P5 PublicationsCorresponds to variant dbSNP:rs1748986Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_046387 | 1 – 70 | Missing in isoform 4. 1 PublicationAdd BLAST | 70 | |
Alternative sequenceiVSP_040642 | 1 | M → MKGSEVSLEKKKKIKM in isoform 2. 1 Publication | 1 | |
Alternative sequenceiVSP_046005 | 1 | M → MFWCGTCFVTNNMKGSEVSL EKKKKIKM in isoform 3. 1 Publication | 1 | |
Alternative sequenceiVSP_046006 | 122 | K → NVSLCLTGWSDHSGVITTHC SLYLLRLMRSSHLSLPSSWD YR in isoform 3 and isoform 4. 2 Publications | 1 | |
Alternative sequenceiVSP_040643 | 538 – 613 | Missing in isoform 2. 1 PublicationAdd BLAST | 76 | |
Alternative sequenceiVSP_046007 | 1485 – 1532 | GKAVP…SGADT → LGVHVKKVSCIGKLGLWRFV IQIISSPRWESSATLRFTDA PCQDVSDAAVSEPRGLLSVS ESQHNAGGHGVFGGRYLLNG KRQPAQCLCHW in isoform 3. 1 PublicationAdd BLAST | 48 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY359881 mRNA Translation: AAQ63404.1 AB011158 mRNA Translation: BAA25512.2 Different initiation. AK302836 mRNA Translation: BAG64028.1 AL135752 Genomic DNA No translation available. AL139021 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80740.1 BC000900 mRNA Translation: AAH00900.1 BC066647 mRNA Translation: AAH66647.2 |
CCDSi | CCDS45115.1 [Q9BVV6-2] CCDS58320.1 [Q9BVV6-3] CCDS58321.1 [Q9BVV6-1] CCDS58322.1 [Q9BVV6-4] |
PIRi | T00344 |
RefSeqi | NP_001231118.1, NM_001244189.1 [Q9BVV6-3] NP_001231119.1, NM_001244190.1 [Q9BVV6-1] NP_001231120.1, NM_001244191.1 NP_001231121.1, NM_001244192.1 [Q9BVV6-4] NP_001231122.1, NM_001244193.1 NP_055564.3, NM_014749.4 [Q9BVV6-2] |
Genome annotation databases
Ensembli | ENST00000261244; ENSP00000261244; ENSG00000100578 [Q9BVV6-2] ENST00000354386; ENSP00000346359; ENSG00000100578 [Q9BVV6-3] ENST00000423743; ENSP00000399427; ENSG00000100578 [Q9BVV6-4] ENST00000556134; ENSP00000452351; ENSG00000100578 [Q9BVV6-4] ENST00000619416; ENSP00000478083; ENSG00000100578 [Q9BVV6-1] |
GeneIDi | 9786 |
KEGGi | hsa:9786 |
UCSCi | uc001xdt.5, human [Q9BVV6-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY359881 mRNA Translation: AAQ63404.1 AB011158 mRNA Translation: BAA25512.2 Different initiation. AK302836 mRNA Translation: BAG64028.1 AL135752 Genomic DNA No translation available. AL139021 Genomic DNA No translation available. CH471061 Genomic DNA Translation: EAW80740.1 BC000900 mRNA Translation: AAH00900.1 BC066647 mRNA Translation: AAH66647.2 |
CCDSi | CCDS45115.1 [Q9BVV6-2] CCDS58320.1 [Q9BVV6-3] CCDS58321.1 [Q9BVV6-1] CCDS58322.1 [Q9BVV6-4] |
PIRi | T00344 |
RefSeqi | NP_001231118.1, NM_001244189.1 [Q9BVV6-3] NP_001231119.1, NM_001244190.1 [Q9BVV6-1] NP_001231120.1, NM_001244191.1 NP_001231121.1, NM_001244192.1 [Q9BVV6-4] NP_001231122.1, NM_001244193.1 NP_055564.3, NM_014749.4 [Q9BVV6-2] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 115130, 16 interactors |
IntActi | Q9BVV6, 8 interactors |
MINTi | Q9BVV6 |
STRINGi | 9606.ENSP00000346359 |
PTM databases
iPTMneti | Q9BVV6 |
PhosphoSitePlusi | Q9BVV6 |
Polymorphism and mutation databases
BioMutai | KIAA0586 |
DMDMi | 327478601 |
Proteomic databases
jPOSTi | Q9BVV6 |
MassIVEi | Q9BVV6 |
MaxQBi | Q9BVV6 |
PeptideAtlasi | Q9BVV6 |
PRIDEi | Q9BVV6 |
ProteomicsDBi | 18876 79236 [Q9BVV6-1] 79237 [Q9BVV6-2] |
Protocols and materials databases
Antibodypediai | 21, 13 antibodies |
Genome annotation databases
Ensembli | ENST00000261244; ENSP00000261244; ENSG00000100578 [Q9BVV6-2] ENST00000354386; ENSP00000346359; ENSG00000100578 [Q9BVV6-3] ENST00000423743; ENSP00000399427; ENSG00000100578 [Q9BVV6-4] ENST00000556134; ENSP00000452351; ENSG00000100578 [Q9BVV6-4] ENST00000619416; ENSP00000478083; ENSG00000100578 [Q9BVV6-1] |
GeneIDi | 9786 |
KEGGi | hsa:9786 |
UCSCi | uc001xdt.5, human [Q9BVV6-1] |
Organism-specific databases
CTDi | 9786 |
DisGeNETi | 9786 |
EuPathDBi | HostDB:ENSG00000100578.14 |
GeneCardsi | KIAA0586 |
GeneReviewsi | KIAA0586 |
HGNCi | HGNC:19960, KIAA0586 |
HPAi | ENSG00000100578, Low tissue specificity |
MalaCardsi | KIAA0586 |
MIMi | 610178, gene 616490, phenotype 616546, phenotype |
neXtProti | NX_Q9BVV6 |
OpenTargetsi | ENSG00000100578 |
Orphaneti | 475, Joubert syndrome 397715, Joubert syndrome with Jeune asphyxiating thoracic dystrophy |
PharmGKBi | PA134992213 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QUXJ, Eukaryota |
GeneTreei | ENSGT00390000012397 |
InParanoidi | Q9BVV6 |
OMAi | HLPARVC |
OrthoDBi | 66287at2759 |
PhylomeDBi | Q9BVV6 |
TreeFami | TF332939 |
Enzyme and pathway databases
PathwayCommonsi | Q9BVV6 |
Miscellaneous databases
BioGRID-ORCSi | 9786, 6 hits in 847 CRISPR screens |
ChiTaRSi | KIAA0586, human |
GenomeRNAii | 9786 |
Pharosi | Q9BVV6, Tbio |
PROi | PR:Q9BVV6 |
RNActi | Q9BVV6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000100578, Expressed in testis and 205 other tissues |
ExpressionAtlasi | Q9BVV6, baseline and differential |
Genevisiblei | Q9BVV6, HS |
Family and domain databases
InterProi | View protein in InterPro IPR029246, TALPID3 |
PANTHERi | PTHR15721, PTHR15721, 1 hit |
Pfami | View protein in Pfam PF15324, TALPID3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TALD3_HUMAN | |
Accessioni | Q9BVV6Primary (citable) accession number: Q9BVV6 Secondary accession number(s): B4DZB6 Q6UV20 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 23, 2002 |
Last sequence update: | April 5, 2011 | |
Last modified: | December 2, 2020 | |
This is version 145 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations