FNDC11

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Fibronectin type III domain-containing protein 11
Gene namesⁱ	Name:FNDC11 Synonyms:C20orf195
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 20

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000125531.6
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28764 FNDC11
neXtProtⁱ	NX_Q9BVV2

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000125531
PharmGKBⁱ	PA142672215

Polymorphism and mutation databases

BioMutaⁱ	C20orf195
DMDMⁱ	74761293

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000232867	1 – 318	Fibronectin type III domain-containing protein 11Add BLAST		318

Proteomic databases

PaxDbⁱ	Q9BVV2
PeptideAtlas More...PeptideAtlasⁱ	Q9BVV2
PRIDEⁱ	Q9BVV2
ProteomicsDBⁱ	79235

PTM databases

iPTMnetⁱ	Q9BVV2
PhosphoSitePlusⁱ	Q9BVV2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000125531 Expressed in 79 organ(s), highest expression level in right testis
CleanExⁱ	HS_C20orf195
ExpressionAtlasⁱ	Q9BVV2 baseline and differential
Genevisibleⁱ	Q9BVV2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA041341

HPAⁱ

HPA041341

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
CALCOCO2	Q13137	4	EBI-744935,EBI-739580
CCDC102B	Q68D86	3	EBI-744935,EBI-10171570
CDA	P32320	5	EBI-744935,EBI-9250559
FAM9B	Q8IZU0	3	EBI-744935,EBI-10175124
GOLGA2	Q08379	3	EBI-744935,EBI-618309
GPBP1	Q86WP2	5	EBI-744935,EBI-2349758
GPBP1	Q86WP2-4	3	EBI-744935,EBI-10300058
HMBOX1	Q6NT76	3	EBI-744935,EBI-2549423
KRT40	Q6A162	3	EBI-744935,EBI-10171697
LZTS2	Q9BRK4	3	EBI-744935,EBI-741037
MAGEA12	P43365	5	EBI-744935,EBI-749530
MDFI	Q99750	3	EBI-744935,EBI-724076
MTUS2	Q5JR59	3	EBI-744935,EBI-742948
RBPMS	Q93062	3	EBI-744935,EBI-740322
REL	Q04864	3	EBI-744935,EBI-307352
SSX2IP	Q9Y2D8	3	EBI-744935,EBI-2212028
TRIM27	P14373	3	EBI-744935,EBI-719493

Protein-protein interaction databases

BioGridⁱ	122493, 25 interactors
IntActⁱ	Q9BVV2, 41 interactors
Molecular INTeraction database More...MINTⁱ	Q9BVV2

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9BVV2
SMRⁱ	Q9BVV2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	210 – 307	Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST		98

Phylogenomic databases

eggNOGⁱ	ENOG410IGYC Eukaryota ENOG410YC0Q LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006008
HOGENOMⁱ	HOG000231855
HOVERGENⁱ	HBG080464
InParanoidⁱ	Q9BVV2
OMAⁱ	WFVTVQP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0D2Y
PhylomeDBⁱ	Q9BVV2
TreeFamⁱ	TF338188

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00063 FN3, 1 hit
InterProⁱ	View protein in InterPro IPR003961 FN3_dom IPR036116 FN3_sf IPR039581 FNDC11
PANTHERⁱ	PTHR14537 PTHR14537, 1 hit
SUPFAMⁱ	SSF49265 SSF49265, 1 hit
PROSITEⁱ	View protein in PROSITE PS50853 FN3, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q9BVV2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSTHVAGLGL DKMKLGNPQS FLDQEEADDQ QLLEPEAWKT YTERRNALRE 
        60         70         80         90        100
FLTSDLSPHL LKRHHARMQL LRKCSYYIEV LPKHLALGDQ NPLVLPSALF 
       110        120        130        140        150
QLIDPWKFQR MKKVGTAQTK IQLLLLGDLL EQLDHGRAEL DALLRSPDPR 
       160        170        180        190        200
PFLADWALVE RRLADVSAVM DSFLTMMVPG RLHVKHRLVS DVSATKIPHI 
       210        220        230        240        250
WLMLSTKMPV VFDRKASAAH QDWARLRWFV TIQPATSEQY ELRFRLLDPR 
       260        270        280        290        300
TQQECAQCGV IPVAACTFDV RNLLPNRSYK FTIKRAETST LVYEPWRDSL 
       310 
TLHTKPEPLE GPALSHSV

Length:318

Mass (Da):36,526

Last modified:June 1, 2001 - v1

Checksum:ⁱ9FDA08CB588A9699

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A0A087X0Q0	A0A087X0Q0_HUMAN		Fibronectin type III domain-contain... Fibronectin type III domain-containing protein 11	FNDC11	81	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL121829 Genomic DNA No translation available. BC000912 mRNA Translation: AAH00912.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS13526.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001306081.1, NM_001319152.1 NP_001306082.1, NM_001319153.1 NP_076964.1, NM_024059.3 XP_011527343.1, XM_011529041.2
UniGeneⁱ	Hs.197755

Genome annotation databases

Ensemblⁱ	ENST00000370097; ENSP00000359115; ENSG00000125531 ENST00000370098; ENSP00000359116; ENSG00000125531 ENST00000615526; ENSP00000480914; ENSG00000125531
GeneIDⁱ	79025
KEGGⁱ	hsa:79025
UCSC genome browser More...UCSCⁱ	uc002yfj.4 human

Protein	Similar proteins		Species	Score	Length	Source
Q9BVV2	Fibronectin type III domain-containing protein 11 (Fragment)		HUMAN		81	UniRef100_Q9BVV2
UPI0005D02204		HUMAN		323

Protein	Similar proteins		Species	Score	Length	Source
Q9BVV2	Fibronectin type III domain-containing protein 11 (Fragment)		HUMAN		81	UniRef90_Q9BVV2
Fibronectin type III domain containing 11		MACFA		323
Uncharacterized protein		MACMU		323
Uncharacterized protein		CERAT		323
Uncharacterized protein		PAPAN		323
+21

Protein	Similar proteins		Species	Score	Length	Source
Q9BVV2	Fibronectin type III domain-containing protein 11		BOVIN		333	UniRef50_Q9BVV2
Fibronectin type III domain-containing protein 11		MOUSE		326
Fibronectin type III domain-containing protein 11 (Fragment)		HUMAN		81
Fibronectin type III domain containing 11		MACFA		323
Uncharacterized protein		MACMU		323
+140

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL121829 Genomic DNA No translation available. BC000912 mRNA Translation: AAH00912.1
CCDSⁱ	CCDS13526.1
RefSeqⁱ	NP_001306081.1, NM_001319152.1 NP_001306082.1, NM_001319153.1 NP_076964.1, NM_024059.3 XP_011527343.1, XM_011529041.2
UniGeneⁱ	Hs.197755

3D structure databases

ProteinModelPortalⁱ	Q9BVV2
SMRⁱ	Q9BVV2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	122493, 25 interactors
IntActⁱ	Q9BVV2, 41 interactors
MINTⁱ	Q9BVV2

PTM databases

iPTMnetⁱ	Q9BVV2
PhosphoSitePlusⁱ	Q9BVV2

Polymorphism and mutation databases

BioMutaⁱ	C20orf195
DMDMⁱ	74761293

Proteomic databases

PaxDbⁱ	Q9BVV2
PeptideAtlasⁱ	Q9BVV2
PRIDEⁱ	Q9BVV2
ProteomicsDBⁱ	79235

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000370097; ENSP00000359115; ENSG00000125531 ENST00000370098; ENSP00000359116; ENSG00000125531 ENST00000615526; ENSP00000480914; ENSG00000125531
GeneIDⁱ	79025
KEGGⁱ	hsa:79025
UCSCⁱ	uc002yfj.4 human

Organism-specific databases

CTDⁱ	79025
EuPathDBⁱ	HostDB:ENSG00000125531.6
GeneCardsⁱ	FNDC11
HGNCⁱ	HGNC:28764 FNDC11
HPAⁱ	HPA041341
neXtProtⁱ	NX_Q9BVV2
OpenTargetsⁱ	ENSG00000125531
PharmGKBⁱ	PA142672215
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IGYC Eukaryota ENOG410YC0Q LUCA
GeneTreeⁱ	ENSGT00390000006008
HOGENOMⁱ	HOG000231855
HOVERGENⁱ	HBG080464
InParanoidⁱ	Q9BVV2
OMAⁱ	WFVTVQP
OrthoDBⁱ	EOG091G0D2Y
PhylomeDBⁱ	Q9BVV2
TreeFamⁱ	TF338188

Miscellaneous databases

GenomeRNAiⁱ	79025
Protein Ontology More...PROⁱ	PR:Q9BVV2

Gene expression databases

Bgeeⁱ	ENSG00000125531 Expressed in 79 organ(s), highest expression level in right testis
CleanExⁱ	HS_C20orf195
ExpressionAtlasⁱ	Q9BVV2 baseline and differential
Genevisibleⁱ	Q9BVV2 HS

Family and domain databases

CDDⁱ	cd00063 FN3, 1 hit
InterProⁱ	View protein in InterPro IPR003961 FN3_dom IPR036116 FN3_sf IPR039581 FNDC11
PANTHERⁱ	PTHR14537 PTHR14537, 1 hit
SUPFAMⁱ	SSF49265 SSF49265, 1 hit
PROSITEⁱ	View protein in PROSITE PS50853 FN3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	FND11_HUMAN
Accessionⁱ	Q9BVV2Primary (citable) accession number: Q9BVV2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM

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UniProtKB - Q9BVV2 (FND11_HUMAN)

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Fibronectin type III domain-containing protein 11

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ