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Entry version 155 (02 Dec 2020)
Sequence version 1 (01 Jun 2001)
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Protein

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

Gene

ST6GALNAC5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Predominantly catalyzes the biosynthesis of ganglioside GD1alpha from GM1b in the brain, by transfering the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of GM1b (PubMed:12668675). GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis (By similarity). Also shows activity towards sialyl Lc4Cer (N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine) generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen (PubMed:12668675).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.56 mM for GMb11 Publication
  2. KM=0.90 mM for sialyl Lc4Cer1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: Glycolipid biosynthesis

    This protein is involved in Glycolipid biosynthesis.1 Publication
    View all proteins of this organism that are known to be involved in Glycolipid biosynthesis.

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionGlycosyltransferase, Transferase
    LigandSialic acid

    Enzyme and pathway databases

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    2.4.99.7, 2681

    Pathway Commons web resource for biological pathway data

    More...
    PathwayCommonsi
    Q9BVH7

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-4085001, Sialic acid metabolism

    Protein family/group databases

    Carbohydrate-Active enZymes

    More...
    CAZyi
    GT29, Glycosyltransferase Family 29

    Chemistry databases

    SwissLipids knowledge resource for lipid biology

    More...
    SwissLipidsi
    SLP:000001365

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC:2.4.99.-1 Publication)
    Alternative name(s):
    GD1 alpha synthase
    GalNAc alpha-2,6-sialyltransferase V
    ST6GalNAc V1 Publication
    Short name:
    ST6GalNAcV
    Sialyltransferase 7E
    Short name:
    SIAT7-E
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:ST6GALNAC5
    Synonyms:SIAT7E
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

    Organism-specific databases

    Eukaryotic Pathogen and Host Database Resources

    More...
    EuPathDBi
    HostDB:ENSG00000117069.14

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:19342, ST6GALNAC5

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    610134, gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q9BVH7

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8CytoplasmicSequence analysis8
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei9 – 29Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
    Topological domaini30 – 336LumenalSequence analysisAdd BLAST307

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    81849

    Open Targets

    More...
    OpenTargetsi
    ENSG00000117069

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA134924485

    Miscellaneous databases

    Pharos NIH Druggable Genome Knowledgebase

    More...
    Pharosi
    Q9BVH7, Tbio

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    ST6GALNAC5

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    21759442

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001492801 – 336Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5Add BLAST336

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi96 ↔ 245By similarity
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi137N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi161N-linked (GlcNAc...) asparagineSequence analysis1

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    Q9BVH7

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q9BVH7

    PeptideAtlas

    More...
    PeptideAtlasi
    Q9BVH7

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q9BVH7

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    79206

    PTM databases

    GlyGen: Computational and Informatics Resources for Glycoscience

    More...
    GlyGeni
    Q9BVH7, 2 sites

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q9BVH7

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q9BVH7

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000117069, Expressed in Ammon's horn and 151 other tissues

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q9BVH7, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q9BVH7, HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    ENSG00000117069, Tissue enhanced (brain)

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGRID)

    More...
    BioGRIDi
    123600, 3 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    Q9BVH7, 2 interactors

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000417583

    Miscellaneous databases

    RNAct, Protein-RNA interaction predictions for model organisms.

    More...
    RNActi
    Q9BVH7, protein

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q9BVH7

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Compositional bias

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi38 – 49Poly-GlnAdd BLAST12

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the glycosyltransferase 29 family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG2692, Eukaryota

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00940000157634

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_061099_0_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q9BVH7

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    HCKDCAL

    Database of Orthologous Groups

    More...
    OrthoDBi
    817470at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q9BVH7

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF323961

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.90.1480.20, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR001675, Glyco_trans_29
    IPR038578, GT29-like_sf
    IPR012163, Sialyl_trans

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00777, Glyco_transf_29, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF005557, Sialyl_trans, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

    Q9BVH7-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MKTLMRHGLA VCLALTTMCT SLLLVYSSLG GQKERPPQQQ QQQQQQQQQA
    60 70 80 90 100
    SATGSSQPAA ESSTQQRPGV PAGPRPLDGY LGVADHKPLK MHCRDCALVT
    110 120 130 140 150
    SSGHLLHSRQ GSQIDQTECV IRMNDAPTRG YGRDVGNRTS LRVIAHSSIQ
    160 170 180 190 200
    RILRNRHDLL NVSQGTVFIF WGPSSYMRRD GKGQVYNNLH LLSQVLPRLK
    210 220 230 240 250
    AFMITRHKML QFDELFKQET GKDRKISNTW LSTGWFTMTI ALELCDRINV
    260 270 280 290 300
    YGMVPPDFCR DPNHPSVPYH YYEPFGPDEC TMYLSHERGR KGSHHRFITE
    310 320 330
    KRVFKNWART FNIHFFQPDW KPESLAINHP ENKPVF
    Length:336
    Mass (Da):38,443
    Last modified:June 1, 2001 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5FDD43D45CA11CE
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    F2Z2C8F2Z2C8_HUMAN
    Alpha-N-acetylgalactosaminide alpha...
    ST6GALNAC5
    236Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AJ507292 mRNA Translation: CAD45372.1
    AK056241 mRNA Translation: BAB71127.1
    AC099060 Genomic DNA No translation available.
    AL035409 Genomic DNA No translation available.
    CH471059 Genomic DNA Translation: EAX06386.1
    BC001201 mRNA Translation: AAH01201.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS673.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_112227.1, NM_030965.2

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000477717; ENSP00000417583; ENSG00000117069

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    81849

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:81849

    UCSC genome browser

    More...
    UCSCi
    uc001dhi.4, human

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    <p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

    Functional Glycomics Gateway - GTase

    ST6GalNAc V

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AJ507292 mRNA Translation: CAD45372.1
    AK056241 mRNA Translation: BAB71127.1
    AC099060 Genomic DNA No translation available.
    AL035409 Genomic DNA No translation available.
    CH471059 Genomic DNA Translation: EAX06386.1
    BC001201 mRNA Translation: AAH01201.1
    CCDSiCCDS673.1
    RefSeqiNP_112227.1, NM_030965.2

    3D structure databases

    SMRiQ9BVH7
    ModBaseiSearch...

    Protein-protein interaction databases

    BioGRIDi123600, 3 interactors
    IntActiQ9BVH7, 2 interactors
    STRINGi9606.ENSP00000417583

    Chemistry databases

    SwissLipidsiSLP:000001365

    Protein family/group databases

    CAZyiGT29, Glycosyltransferase Family 29

    PTM databases

    GlyGeniQ9BVH7, 2 sites
    iPTMnetiQ9BVH7
    PhosphoSitePlusiQ9BVH7

    Polymorphism and mutation databases

    BioMutaiST6GALNAC5
    DMDMi21759442

    Proteomic databases

    MassIVEiQ9BVH7
    PaxDbiQ9BVH7
    PeptideAtlasiQ9BVH7
    PRIDEiQ9BVH7
    ProteomicsDBi79206

    Protocols and materials databases

    Antibodypedia a portal for validated antibodies

    More...
    Antibodypediai
    33478, 99 antibodies

    The DNASU plasmid repository

    More...
    DNASUi
    81849

    Genome annotation databases

    EnsembliENST00000477717; ENSP00000417583; ENSG00000117069
    GeneIDi81849
    KEGGihsa:81849
    UCSCiuc001dhi.4, human

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    81849
    DisGeNETi81849
    EuPathDBiHostDB:ENSG00000117069.14

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    ST6GALNAC5
    HGNCiHGNC:19342, ST6GALNAC5
    HPAiENSG00000117069, Tissue enhanced (brain)
    MIMi610134, gene
    neXtProtiNX_Q9BVH7
    OpenTargetsiENSG00000117069
    PharmGKBiPA134924485

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG2692, Eukaryota
    GeneTreeiENSGT00940000157634
    HOGENOMiCLU_061099_0_0_1
    InParanoidiQ9BVH7
    OMAiHCKDCAL
    OrthoDBi817470at2759
    PhylomeDBiQ9BVH7
    TreeFamiTF323961

    Enzyme and pathway databases

    BRENDAi2.4.99.7, 2681
    PathwayCommonsiQ9BVH7
    ReactomeiR-HSA-4085001, Sialic acid metabolism

    Miscellaneous databases

    BioGRID ORCS database of CRISPR phenotype screens

    More...
    BioGRID-ORCSi
    81849, 6 hits in 842 CRISPR screens

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...
    ChiTaRSi
    ST6GALNAC5, human

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    81849
    PharosiQ9BVH7, Tbio

    Protein Ontology

    More...
    PROi
    PR:Q9BVH7
    RNActiQ9BVH7, protein

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000117069, Expressed in Ammon's horn and 151 other tissues
    ExpressionAtlasiQ9BVH7, baseline and differential
    GenevisibleiQ9BVH7, HS

    Family and domain databases

    Gene3Di3.90.1480.20, 1 hit
    InterProiView protein in InterPro
    IPR001675, Glyco_trans_29
    IPR038578, GT29-like_sf
    IPR012163, Sialyl_trans
    PfamiView protein in Pfam
    PF00777, Glyco_transf_29, 1 hit
    PIRSFiPIRSF005557, Sialyl_trans, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

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    ProtoNeti
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    MobiDB: a database of protein disorder and mobility annotations

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    MobiDBi
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    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSIA7E_HUMAN
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BVH7
    Secondary accession number(s): B1AK82
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2002
    Last sequence update: June 1, 2001
    Last modified: December 2, 2020
    This is version 155 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families
    4. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
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