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Entry version 137 (16 Oct 2019)
Sequence version 1 (01 Jun 2001)
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Protein

Phosphatidylserine synthase 2

Gene

PTDSS2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited in both the MAM and the ER per se by ethanolamine. Requires calcium ions.1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=120 µM for serine (in the presence of 1 mM PE)1 Publication
  1. Vmax=0.57 mmol/h/mg enzyme1 Publication

pH dependencei

Optimum pH is around 7.5.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: phosphatidylserine biosynthesis

This protein is involved in the pathway phosphatidylserine biosynthesis, which is part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the pathway phosphatidylserine biosynthesis and in Phospholipid metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:HS10846-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.8.29 2681

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1483101 Synthesis of PS

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00948

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000001061

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidylserine synthase 2 (EC:2.7.8.29)
Short name:
PSS-2
Short name:
PtdSer synthase 2
Alternative name(s):
Serine-exchange enzyme II
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PTDSS2
Synonyms:PSS2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15463 PTDSS2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612793 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BVG9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 62CytoplasmicSequence analysisAdd BLAST62
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Topological domaini84 – 96LumenalSequence analysisAdd BLAST13
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Topological domaini118 – 126CytoplasmicSequence analysis9
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Topological domaini148 – 313LumenalSequence analysisAdd BLAST166
Transmembranei314 – 334HelicalSequence analysisAdd BLAST21
Topological domaini335CytoplasmicSequence analysis1
Transmembranei336 – 356HelicalSequence analysisAdd BLAST21
Topological domaini357 – 376LumenalSequence analysisAdd BLAST20
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 403CytoplasmicSequence analysis6
Transmembranei404 – 424HelicalSequence analysisAdd BLAST21
Topological domaini425 – 487LumenalSequence analysisAdd BLAST63

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000174915

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33940

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BVG9

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00144 Phosphatidyl serine

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PTDSS2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
49036457

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000568321 – 487Phosphatidylserine synthase 2Add BLAST487

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei16PhosphoserineCombined sources1
Modified residuei24PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi181N-linked (GlcNAc...) asparagine1 Publication1
Modified residuei485PhosphothreonineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BVG9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BVG9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BVG9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BVG9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BVG9

PeptideAtlas

More...
PeptideAtlasi
Q9BVG9

PRoteomics IDEntifications database

More...
PRIDEi
Q9BVG9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79205

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1602

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BVG9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BVG9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9BVG9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000174915 Expressed in 184 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BVG9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BVG9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038928
HPA038929

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123499, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BVG9, 7 interactors

Molecular INTeraction database

More...
MINTi
Q9BVG9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000308258

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2735 Eukaryota
ENOG410XS7H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063576

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000005791

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BVG9

KEGG Orthology (KO)

More...
KOi
K08730

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIMDVIL

Database of Orthologous Groups

More...
OrthoDBi
818196at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BVG9

TreeFam database of animal gene trees

More...
TreeFami
TF300012

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004277 PSS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03034 PSS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9BVG9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRGERRDAG GPRPESPVPA GRASLEEPPD GPSAGQATGP GEGRRSTESE
60 70 80 90 100
VYDDGTNTFF WRAHTLTVLF ILTCTLGYVT LLEETPQDTA YNTKRGIVAS
110 120 130 140 150
ILVFLCFGVT QAKDGPFSRP HPAYWRFWLC VSVVYELFLI FILFQTVQDG
160 170 180 190 200
RQFLKYVDPK LGVPLPERDY GGNCLIYDPD NETDPFHNIW DKLDGFVPAH
210 220 230 240 250
FLGWYLKTLM IRDWWMCMII SVMFEFLEYS LEHQLPNFSE CWWDHWIMDV
260 270 280 290 300
LVCNGLGIYC GMKTLEWLSL KTYKWQGLWN IPTYKGKMKR IAFQFTPYSW
310 320 330 340 350
VRFEWKPASS LRRWLAVCGI ILVFLLAELN TFYLKFVLWM PPEHYLVLLR
360 370 380 390 400
LVFFVNVGGV AMREIYDFMD DPKPHKKLGP QAWLVAAITA TELLIVVKYD
410 420 430 440 450
PHTLTLSLPF YISQCWTLGS VLALTWTVWR FFLRDITLRY KETRWQKWQN
460 470 480
KDDQGSTVGN GDQHPLGLDE DLLGPGVAEG EGAPTPN
Length:487
Mass (Da):56,253
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE02508F894841A4F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0J9YWQ2A0A0J9YWQ2_HUMAN
Phosphatidylserine synthase 2
PTDSS2
393Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PS47E9PS47_HUMAN
Phosphatidylserine synthase 2
PTDSS2
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PLE4E9PLE4_HUMAN
Phosphatidylserine synthase 2
PTDSS2
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL834357 mRNA Translation: CAD39022.1
AC137894 Genomic DNA No translation available.
AC138230 Genomic DNA No translation available.
BC001210 mRNA Translation: AAH01210.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7696.1

NCBI Reference Sequences

More...
RefSeqi
NP_110410.1, NM_030783.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000308020; ENSP00000308258; ENSG00000174915

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
81490

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:81490

UCSC genome browser

More...
UCSCi
uc001lpj.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL834357 mRNA Translation: CAD39022.1
AC137894 Genomic DNA No translation available.
AC138230 Genomic DNA No translation available.
BC001210 mRNA Translation: AAH01210.1
CCDSiCCDS7696.1
RefSeqiNP_110410.1, NM_030783.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123499, 8 interactors
IntActiQ9BVG9, 7 interactors
MINTiQ9BVG9
STRINGi9606.ENSP00000308258

Chemistry databases

DrugBankiDB00144 Phosphatidyl serine
SwissLipidsiSLP:000001061

PTM databases

GlyConnecti1602
iPTMnetiQ9BVG9
PhosphoSitePlusiQ9BVG9
SwissPalmiQ9BVG9

Polymorphism and mutation databases

BioMutaiPTDSS2
DMDMi49036457

Proteomic databases

EPDiQ9BVG9
jPOSTiQ9BVG9
MassIVEiQ9BVG9
MaxQBiQ9BVG9
PaxDbiQ9BVG9
PeptideAtlasiQ9BVG9
PRIDEiQ9BVG9
ProteomicsDBi79205

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
81490

Genome annotation databases

EnsembliENST00000308020; ENSP00000308258; ENSG00000174915
GeneIDi81490
KEGGihsa:81490
UCSCiuc001lpj.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81490

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PTDSS2
HGNCiHGNC:15463 PTDSS2
HPAiHPA038928
HPA038929
MIMi612793 gene
neXtProtiNX_Q9BVG9
OpenTargetsiENSG00000174915
PharmGKBiPA33940

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2735 Eukaryota
ENOG410XS7H LUCA
GeneTreeiENSGT00530000063576
HOGENOMiHOG000005791
InParanoidiQ9BVG9
KOiK08730
OMAiWIMDVIL
OrthoDBi818196at2759
PhylomeDBiQ9BVG9
TreeFamiTF300012

Enzyme and pathway databases

UniPathwayiUPA00948
BioCyciMetaCyc:HS10846-MONOMER
BRENDAi2.7.8.29 2681
ReactomeiR-HSA-1483101 Synthesis of PS

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
81490
PharosiQ9BVG9

Protein Ontology

More...
PROi
PR:Q9BVG9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000174915 Expressed in 184 organ(s), highest expression level in right testis
ExpressionAtlasiQ9BVG9 baseline and differential
GenevisibleiQ9BVG9 HS

Family and domain databases

InterProiView protein in InterPro
IPR004277 PSS
PfamiView protein in Pfam
PF03034 PSS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTSS2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BVG9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2004
Last sequence update: June 1, 2001
Last modified: October 16, 2019
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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