UniProtKB - Q9BVE2 (Q9BVE2_HUMAN)
Protein
Submitted name:
CDC2L5 protein
Gene
CDK13
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine/threonine kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase |
Ligand | ATP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: CDC2L5 proteinImportedSubmitted name: Cyclin-dependent kinase 13Imported |
Gene namesi | Name:CDK13Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000065883.14 |
HGNCi | HGNC:1733, CDK13 |
Expressioni
Gene expression databases
Bgeei | ENSG00000065883, Expressed in inferior vagus X ganglion and 257 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 91 – 324 | Protein kinaseInterPro annotationAdd BLAST | 234 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 35 – 71 | DisorderedSequence analysisAdd BLAST | 37 |
Sequence similaritiesi
Belongs to the protein kinase superfamily.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000157852 |
HOGENOMi | CLU_000288_181_1_1 |
OrthoDBi | 925637at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
Q9BVE2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPEDKEADS LRGNISVKAV KKEVEKKLRC LLADLPLPPE LPGGDDLSKS
60 70 80 90 100
PEEKKTATQL HSKRRPKICG PRYGETKEKD IDWGKRCVDK FDIIGIIGEG
110 120 130 140 150
TYGQVYKARD KDTGEMVALK KVRLDNEKEG FPITAIREIK ILRQLTHQSI
160 170 180 190 200
INMKEIVTDK EDALDFKKDK GAFYLVFEYM DHDLMGLLES GLVHFNENHI
210 220 230 240 250
KSFMRQLMEG LDYCHKKNFL HRDIKCSNIL LNNRGQIKLA DFGLARLYSS
260 270 280 290 300
EESRPYTNKV ITLWYRPPEL LLGEERYTPA IDVWSCGCIL GELFTKKPIF
310 320
QANQELAQLE LIRHEENEVS DKQI
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ14004 | CDK13_HUMAN | Cyclin-dependent kinase 13 | CDK13 CDC2L, CDC2L5, CHED, KIAA1791 | 1,512 | Annotation score: | ||
A0A2R8YD28 | A0A2R8YD28_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 456 | Annotation score: | ||
A0A087X209 | A0A087X209_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 418 | Annotation score: | ||
A0A2R8Y4Z0 | A0A2R8Y4Z0_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 1,308 | Annotation score: | ||
A0A2R8Y7W5 | A0A2R8Y7W5_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 1,099 | Annotation score: | ||
A0A2R8YF61 | A0A2R8YF61_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 915 | Annotation score: | ||
A0A2R8Y644 | A0A2R8Y644_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 239 | Annotation score: | ||
A0A2R8Y7Y0 | A0A2R8Y7Y0_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 257 | Annotation score: | ||
A0A2R8YCQ1 | A0A2R8YCQ1_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 288 | Annotation score: | ||
A0A2R8YFE7 | A0A2R8YFE7_HUMAN | Cyclin-dependent kinase 13 | CDK13 | 279 | Annotation score: | ||
There is more potential isoformShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006023 Genomic DNA No translation available. AC072061 Genomic DNA No translation available. BC001274 mRNA Translation: AAH01274.1 |
RefSeqi | NP_003709.3, NM_003718.4 NP_112557.2, NM_031267.3 |
Genome annotation databases
Ensembli | ENST00000613626; ENSP00000480835; ENSG00000065883 |
GeneIDi | 8621 |
KEGGi | hsa:8621 |
UCSCi | uc064dab.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006023 Genomic DNA No translation available. AC072061 Genomic DNA No translation available. BC001274 mRNA Translation: AAH01274.1 |
RefSeqi | NP_003709.3, NM_003718.4 NP_112557.2, NM_031267.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9BVE2, 2 interactors |
Protocols and materials databases
Antibodypediai | 26726, 189 antibodies |
DNASUi | 8621 |
Genome annotation databases
Ensembli | ENST00000613626; ENSP00000480835; ENSG00000065883 |
GeneIDi | 8621 |
KEGGi | hsa:8621 |
UCSCi | uc064dab.1, human |
Organism-specific databases
CTDi | 8621 |
EuPathDBi | HostDB:ENSG00000065883.14 |
HGNCi | HGNC:1733, CDK13 |
OpenTargetsi | ENSG00000065883 |
PharmGKBi | PA26264 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157852 |
HOGENOMi | CLU_000288_181_1_1 |
OrthoDBi | 925637at2759 |
Miscellaneous databases
BioGRID-ORCSi | 8621, 59 hits in 873 CRISPR screens |
ChiTaRSi | CDK13, human |
GenomeRNAii | 8621 |
Gene expression databases
Bgeei | ENSG00000065883, Expressed in inferior vagus X ganglion and 257 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9BVE2_HUMAN | |
Accessioni | Q9BVE2Primary (citable) accession number: Q9BVE2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |