UniProtKB - Q9BVE2 (Q9BVE2_HUMAN)

BLAST

>tr|Q9BVE2|Q9BVE2_HUMAN CDC2L5 protein OS=Homo sapiens OX=9606 GN=CDK13 PE=1 SV=1
MLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQL
HSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALK
KVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYM
DHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLA
DFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIF
QANQELAQLELIRHEENEVSDKQI

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History
Entry version 133 (12 Sep 2018)
Sequence version 1 (01 Jun 2001)
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Protein

Submitted name:

CDC2L5 protein

Gene

CDK13

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
protein serine/threonine kinase activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
Ligand	ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: CDC2L5 proteinImported Submitted name: Cyclin-dependent kinase 13Imported
Gene namesⁱ	Name:CDK13Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 7

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000065883.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1733 CDK13

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000065883
PharmGKBⁱ	PA26264

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	Q9BVE2

PRIDEⁱ

Q9BVE2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000065883 Expressed in 244 organ(s), highest expression level in inferior vagus X ganglion

Bgeeⁱ

ENSG00000065883 Expressed in 244 organ(s), highest expression level in inferior vagus X ganglion

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	Q9BVE2, 3 interactors

IntActⁱ

Q9BVE2, 3 interactors

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	91 – 324	Protein kinaseInterPro annotationAdd BLAST		234

Sequence similaritiesⁱ

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0600 Eukaryota ENOG410XPIR LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00890000139396
HOGENOMⁱ	HOG000152150
KEGG Orthology (KO) More...KOⁱ	K08819

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR017441 Protein_kinase_ATP_BS IPR008271 Ser/Thr_kinase_AS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069 Pkinase, 1 hit
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS00107 PROTEIN_KINASE_ATP, 1 hit PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.ⁱShow all

Q9BVE2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MLPEDKEADS LRGNISVKAV KKEVEKKLRC LLADLPLPPE LPGGDDLSKS 
        60         70         80         90        100
PEEKKTATQL HSKRRPKICG PRYGETKEKD IDWGKRCVDK FDIIGIIGEG 
       110        120        130        140        150
TYGQVYKARD KDTGEMVALK KVRLDNEKEG FPITAIREIK ILRQLTHQSI 
       160        170        180        190        200
INMKEIVTDK EDALDFKKDK GAFYLVFEYM DHDLMGLLES GLVHFNENHI 
       210        220        230        240        250
KSFMRQLMEG LDYCHKKNFL HRDIKCSNIL LNNRGQIKLA DFGLARLYSS 
       260        270        280        290        300
EESRPYTNKV ITLWYRPPEL LLGEERYTPA IDVWSCGCIL GELFTKKPIF 
       310        320 
QANQELAQLE LIRHEENEVS DKQI

Length:324

Mass (Da):37,339

Last modified:June 1, 2001 - v1

Checksum:ⁱ5433011D95D0F2CB

Computationally mapped potential isoform sequencesⁱ

There are 11 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation
	Q14004	CDK13_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13, EC 2.7.11.22, EC 2.7.11.23 (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13, hCDK13) (Cholinesterase-related cell division controller)	CDK13 CDC2L, CDC2L5, CHED, KIAA1791	1,512	Annotation score:
	A0A087X209	A0A087X209_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	418	Annotation score:
	A0A2R8Y7W5	A0A2R8Y7W5_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	1,099	Annotation score:
	A0A2R8YD28	A0A2R8YD28_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	456	Annotation score:
	A0A2R8Y644	A0A2R8Y644_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	239	Annotation score:
	A0A2R8Y4Z0	A0A2R8Y4Z0_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	1,308	Annotation score:
	A0A2R8YEB7	A0A2R8YEB7_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	143	Annotation score:
	A0A2R8YF61	A0A2R8YF61_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	915	Annotation score:
	A0A2R8YCQ1	A0A2R8YCQ1_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	288	Annotation score:
	A0A2R8YFE7	A0A2R8YFE7_HUMAN	Cyclin-dependent kinase 13 Cyclin-dependent kinase 13	CDK13	279	Annotation score:
There is more potential isoformShow all

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC006023 Genomic DNA No translation available. AC072061 Genomic DNA No translation available. BC001274 mRNA Translation: AAH01274.1
NCBI Reference Sequences More...RefSeqⁱ	NP_003709.3, NM_003718.4 NP_112557.2, NM_031267.3
UniGeneⁱ	Hs.233552

Genome annotation databases

Ensemblⁱ	ENST00000613626; ENSP00000480835; ENSG00000065883
GeneIDⁱ	8621
KEGGⁱ	hsa:8621
UCSC genome browser More...UCSCⁱ	uc064dab.1 human

Protein	Similar proteins		Species	Score	Length	Source
Q9BVE2	Cyclin-dependent kinase 13 (Fragment)		HUMAN		456	UniRef90_Q9BVE2
Cyclin-dependent kinase 13 (Fragment)		NEOVI		560

Protein	Similar proteins		Species	Score	Length	Source
Q9BVE2	Cyclin-dependent kinase 13 (Fragment)		HUMAN		456	UniRef50_Q9BVE2
Cyclin-dependent kinase 13 (Fragment)		NEOVI		560
UPI0004D058D9		GALVR		573

Entry informationⁱ

Entry nameⁱ	Q9BVE2_HUMAN
Accessionⁱ	Q9BVE2Primary (citable) accession number: Q9BVE2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 2001
	Last sequence update:	June 1, 2001
	Last modified:	September 12, 2018
	This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - Q9BVE2 (Q9BVE2_HUMAN)

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CDC2L5 protein

CDK13

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9BVE2 (Q9BVE2_HUMAN)

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CDC2L5 protein

CDK13

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Computationally mapped potential isoform sequencesi

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Computationally mapped potential isoform sequencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ