Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 140 (26 Feb 2020)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

THUMP domain-containing protein 3

Gene

THUMPD3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
THUMP domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:THUMPD3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24493 THUMPD3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BV44

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000134077

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134969445

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BV44 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
THUMPD3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74733286

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002597691 – 507THUMP domain-containing protein 3Add BLAST507

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BV44

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BV44

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BV44

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BV44

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BV44

PeptideAtlas

More...
PeptideAtlasi
Q9BV44

PRoteomics IDEntifications database

More...
PRIDEi
Q9BV44

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79168

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BV44

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BV44

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000134077 Expressed in testis and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BV44 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BV44 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA036170
HPA036171

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q9UI303EBI-373253,EBI-373326

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117420, 43 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BV44, 23 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000339532

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BV44 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini165 – 285THUMPPROSITE-ProRule annotationAdd BLAST121

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi140 – 148Poly-Lys9

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the methyltransferase superfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEVP Eukaryota
COG0116 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063557

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_045692_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BV44

Identification of Orthologs from Complete Genome Data

More...
OMAi
KKKNWDL

Database of Orthologous Groups

More...
OrthoDBi
674030at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BV44

TreeFam database of animal gene trees

More...
TreeFami
TF313093

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000241 RNA_methylase_dom
IPR029063 SAM-dependent_MTases
IPR004114 THUMP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02926 THUMP, 1 hit
PF01170 UPF0020, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00981 THUMP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335 SSF53335, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51165 THUMP, 1 hit
PS01261 UPF0020, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q9BV44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCDIEEATNQ LLDVNLHENQ KSVQVTESDL GSESELLVTI GATVPTGFEQ
60 70 80 90 100
TAADEVREKL GSSCKISRDR GKIYFVISVE SLAQVHCLRS VDNLFVVVQE
110 120 130 140 150
FQDYQFKQTK EEVLKDFEDL AGKLPWSNPL KVWKINASFK KKKAKRKKIN
160 170 180 190 200
QNSSKEKINN GQEVKIDQRN VKKEFTSHAL DSHILDYYEN PAIKEDVSTL
210 220 230 240 250
IGDDLASCKD ETDESSKEET EPQVLKFRVT CNRAGEKHCF TSNEAARDFG
260 270 280 290 300
GAVQDYFKWK ADMTNFDVEV LLNIHDNEVI VGIALTEESL HRRNITHFGP
310 320 330 340 350
TTLRSTLAYG MLRLCDPLPY DIIVDPMCGT GAIPIEGATE WSDCFHIAGD
360 370 380 390 400
NNPLAVNRAA NNIASLLTKS QIKEGKPSWG LPIDAVQWDI CNLPLRTGSV
410 420 430 440 450
DIIVTDLPFG KRMGSKKRNW NLYPACLREM SRVCTPTTGR AVLLTQDTKC
460 470 480 490 500
FTKALSGMRH VWRKVDTVWV NVGGLRAAVY VLIRTPQAFV HPSEQDGERG

TLWQCKE
Length:507
Mass (Da):57,003
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0CE5587AEE817C19
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C3J3H7C3J3_HUMAN
THUMP domain-containing protein 3
THUMPD3
269Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C0R6H7C0R6_HUMAN
THUMP domain-containing protein 3
THUMPD3
232Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J9V2C9J9V2_HUMAN
THUMP domain-containing protein 3
THUMPD3
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JP31C9JP31_HUMAN
THUMP domain-containing protein 3
THUMPD3
40Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti499R → S in BAA91832 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_028976459R → Q1 PublicationCorresponds to variant dbSNP:rs1129174Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK001680 mRNA Translation: BAA91832.1
AK023263 mRNA Translation: BAB14495.1
BC001622 mRNA Translation: AAH01622.1
BC010421 mRNA Translation: AAH10421.1
AL117483 mRNA Translation: CAB55956.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2573.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T17266

NCBI Reference Sequences

More...
RefSeqi
NP_001107564.1, NM_001114092.1
NP_056268.2, NM_015453.2
XP_005265078.1, XM_005265021.4
XP_005265079.1, XM_005265022.4
XP_005265080.1, XM_005265023.3
XP_005265081.1, XM_005265024.4
XP_006713149.1, XM_006713086.3
XP_011531872.1, XM_011533570.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000345094; ENSP00000339532; ENSG00000134077
ENST00000452837; ENSP00000395893; ENSG00000134077
ENST00000515662; ENSP00000424064; ENSG00000134077

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
25917

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:25917

UCSC genome browser

More...
UCSCi
uc003brn.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001680 mRNA Translation: BAA91832.1
AK023263 mRNA Translation: BAB14495.1
BC001622 mRNA Translation: AAH01622.1
BC010421 mRNA Translation: AAH10421.1
AL117483 mRNA Translation: CAB55956.1
CCDSiCCDS2573.1
PIRiT17266
RefSeqiNP_001107564.1, NM_001114092.1
NP_056268.2, NM_015453.2
XP_005265078.1, XM_005265021.4
XP_005265079.1, XM_005265022.4
XP_005265080.1, XM_005265023.3
XP_005265081.1, XM_005265024.4
XP_006713149.1, XM_006713086.3
XP_011531872.1, XM_011533570.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi117420, 43 interactors
IntActiQ9BV44, 23 interactors
STRINGi9606.ENSP00000339532

PTM databases

iPTMnetiQ9BV44
PhosphoSitePlusiQ9BV44

Polymorphism and mutation databases

BioMutaiTHUMPD3
DMDMi74733286

Proteomic databases

EPDiQ9BV44
jPOSTiQ9BV44
MassIVEiQ9BV44
MaxQBiQ9BV44
PaxDbiQ9BV44
PeptideAtlasiQ9BV44
PRIDEiQ9BV44
ProteomicsDBi79168

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
25917

Genome annotation databases

EnsembliENST00000345094; ENSP00000339532; ENSG00000134077
ENST00000452837; ENSP00000395893; ENSG00000134077
ENST00000515662; ENSP00000424064; ENSG00000134077
GeneIDi25917
KEGGihsa:25917
UCSCiuc003brn.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25917

GeneCards: human genes, protein and diseases

More...
GeneCardsi
THUMPD3
HGNCiHGNC:24493 THUMPD3
HPAiHPA036170
HPA036171
neXtProtiNX_Q9BV44
OpenTargetsiENSG00000134077
PharmGKBiPA134969445

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEVP Eukaryota
COG0116 LUCA
GeneTreeiENSGT00530000063557
HOGENOMiCLU_045692_0_0_1
InParanoidiQ9BV44
OMAiKKKNWDL
OrthoDBi674030at2759
PhylomeDBiQ9BV44
TreeFamiTF313093

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
THUMPD3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
25917
PharosiQ9BV44 Tdark

Protein Ontology

More...
PROi
PR:Q9BV44
RNActiQ9BV44 protein

Gene expression databases

BgeeiENSG00000134077 Expressed in testis and 200 other tissues
ExpressionAtlasiQ9BV44 baseline and differential
GenevisibleiQ9BV44 HS

Family and domain databases

InterProiView protein in InterPro
IPR000241 RNA_methylase_dom
IPR029063 SAM-dependent_MTases
IPR004114 THUMP_dom
PfamiView protein in Pfam
PF02926 THUMP, 1 hit
PF01170 UPF0020, 1 hit
SMARTiView protein in SMART
SM00981 THUMP, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS51165 THUMP, 1 hit
PS01261 UPF0020, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTHUM3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BV44
Secondary accession number(s): Q9H8V6, Q9NVC1, Q9UFS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: June 1, 2001
Last modified: February 26, 2020
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again