Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 159 (16 Oct 2019)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein 426

Gene

ZNF426

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri146 – 174C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST29
Zinc fingeri224 – 246C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri280 – 302C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri308 – 330C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri336 – 358C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri364 – 386C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri392 – 414C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri420 – 442C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 470C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri476 – 498C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri504 – 526C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri532 – 554C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 426
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF426
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20725 ZNF426

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BUY5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000130818

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134991761

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BUY5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF426

Domain mapping of disease mutations (DMDM)

More...
DMDMi
34925651

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475761 – 554Zinc finger protein 426Add BLAST554

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BUY5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BUY5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BUY5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BUY5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BUY5

PeptideAtlas

More...
PeptideAtlasi
Q9BUY5

PRoteomics IDEntifications database

More...
PRIDEi
Q9BUY5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79143

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BUY5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BUY5

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9BUY5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000130818 Expressed in 224 organ(s), highest expression level in prostate gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BUY5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BUY5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029342

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122536, 20 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BUY5, 45 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000439017

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BUY5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 112KRABPROSITE-ProRule annotationAdd BLAST71

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri146 – 174C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST29
Zinc fingeri224 – 246C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri280 – 302C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri308 – 330C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri336 – 358C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri364 – 386C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri392 – 414C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri420 – 442C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 470C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri476 – 498C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri504 – 526C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri532 – 554C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163292

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BUY5

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
WEMQLEA

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BUY5

TreeFam database of animal gene trees

More...
TreeFami
TF342172

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00614 ZnF_BED, 1 hit
SM00355 ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 11 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9BUY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAADLSHGH YLSGDPVCLH EEKTPAGRIV ADCLTDCYQD SVTFDDVAVD
60 70 80 90 100
FTQEEWTLLD STQRSLYSDV MLENYKNLAT VGGQIIKPSL ISWLEQEESR
110 120 130 140 150
TVQGGVLQGW EMRLETQWSI LQQDFLRGQT SIGIQLEGKH NGRELCDCEQ
160 170 180 190 200
CGEVFSEHSC LKTHVRTQST GNTHDCNQYG KDFLTLCEKT STGEKLSEFN
210 220 230 240 250
QSEKIFSLTP NIVYQRTSTQ EKSFECSHCG KSFINESYLQ AHMRTHNGEK
260 270 280 290 300
LYEWRNYGPG FIDSTSLSVL IETLNAKKPY KCKECGKGYR YPAYLSIHMR
310 320 330 340 350
THTGEKPYEC KECGKAFNYS NSFQIHGRTH TGEKPYVCKE CGKAFTQYSG
360 370 380 390 400
LSMHVRSHSG DKPYECKECG KSFLTSSRLI QHIRTHTGEK PFVCVECGKA
410 420 430 440 450
FAVSSNLSGH LRTHTEEKAC ECKICGKVFG YPSCLNNHMR THSAQKPYTC
460 470 480 490 500
KECGKAFNYS THLKIHMRIH TGEKPYECKQ CGKAFSHSSS FQIHERTHTG
510 520 530 540 550
EKPYECKECG KAFTCSSSFR IHEKTHTEEK PYKCQQCGKA YSHPRSLRRH

EQIH
Length:554
Mass (Da):63,106
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8490888CC9537F9C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7ER43K7ER43_HUMAN
Zinc finger protein 426
ZNF426
516Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EME3K7EME3_HUMAN
Zinc finger protein 426
ZNF426
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GUG0A0A1B0GUG0_HUMAN
Zinc finger protein 426
ZNF426
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0242144A → V. Corresponds to variant dbSNP:rs2042200Ensembl.1
Natural variantiVAR_052824219T → A. Corresponds to variant dbSNP:rs10420644Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK095759 mRNA Translation: BAG53124.1
CH471106 Genomic DNA Translation: EAW84039.1
BC001791 mRNA Translation: AAH01791.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12215.1

NCBI Reference Sequences

More...
RefSeqi
NP_001304984.1, NM_001318055.1
NP_001304985.1, NM_001318056.1
NP_077011.1, NM_024106.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000253115; ENSP00000253115; ENSG00000130818
ENST00000535489; ENSP00000439017; ENSG00000130818

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79088

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79088

UCSC genome browser

More...
UCSCi
uc002mlq.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095759 mRNA Translation: BAG53124.1
CH471106 Genomic DNA Translation: EAW84039.1
BC001791 mRNA Translation: AAH01791.1
CCDSiCCDS12215.1
RefSeqiNP_001304984.1, NM_001318055.1
NP_001304985.1, NM_001318056.1
NP_077011.1, NM_024106.2

3D structure databases

SMRiQ9BUY5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122536, 20 interactors
IntActiQ9BUY5, 45 interactors
STRINGi9606.ENSP00000439017

PTM databases

iPTMnetiQ9BUY5
PhosphoSitePlusiQ9BUY5
SwissPalmiQ9BUY5

Polymorphism and mutation databases

BioMutaiZNF426
DMDMi34925651

Proteomic databases

EPDiQ9BUY5
jPOSTiQ9BUY5
MassIVEiQ9BUY5
MaxQBiQ9BUY5
PaxDbiQ9BUY5
PeptideAtlasiQ9BUY5
PRIDEiQ9BUY5
ProteomicsDBi79143

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
79088

Genome annotation databases

EnsembliENST00000253115; ENSP00000253115; ENSG00000130818
ENST00000535489; ENSP00000439017; ENSG00000130818
GeneIDi79088
KEGGihsa:79088
UCSCiuc002mlq.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79088

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF426
HGNCiHGNC:20725 ZNF426
HPAiHPA029342
neXtProtiNX_Q9BUY5
OpenTargetsiENSG00000130818
PharmGKBiPA134991761

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163292
HOGENOMiHOG000234617
InParanoidiQ9BUY5
KOiK09228
OMAiWEMQLEA
OrthoDBi1318335at2759
PhylomeDBiQ9BUY5
TreeFamiTF342172

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF426 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79088
PharosiQ9BUY5

Protein Ontology

More...
PROi
PR:Q9BUY5

Gene expression databases

BgeeiENSG00000130818 Expressed in 224 organ(s), highest expression level in prostate gland
ExpressionAtlasiQ9BUY5 baseline and differential
GenevisibleiQ9BUY5 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 10 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00614 ZnF_BED, 1 hit
SM00355 ZnF_C2H2, 12 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 11 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN426_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BUY5
Secondary accession number(s): B3KTL2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: June 1, 2001
Last modified: October 16, 2019
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again