UniProtKB - Q9BUM1 (G6PC3_HUMAN)
Protein
Glucose-6-phosphatase 3
Gene
G6PC3
Organism
Homo sapiens (Human)
Status
Functioni
Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function.3 Publications
Caution
According to PubMed:12370122, it has no hydrolytic activity.Curated
Catalytic activityi
- EC:3.1.3.91 Publication
Activity regulationi
Inhibited by vanadate.1 Publication
Kineticsi
8 times less active compared to G6PC under the same experimental conditions.
- KM=1.0 mM for glucose-6-phosphate (at pH 5.5)2 Publications
- KM=2.0 mM for glucose-6-phosphate (at pH 6.5)2 Publications
: gluconeogenesis Pathwayi
This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 79 | SubstrateSequence analysis | 1 | |
Active sitei | 114 | Proton donorSequence analysis | 1 | |
Binding sitei | 161 | SubstrateSequence analysis | 1 | |
Active sitei | 167 | Nucleophile1 Publication | 1 |
GO - Molecular functioni
- glucose-6-phosphatase activity Source: UniProtKB
GO - Biological processi
- gluconeogenesis Source: GO_Central
- glucose 6-phosphate metabolic process Source: GO_Central
- glucose-6-phosphate transport Source: Ensembl
Keywordsi
Molecular function | Hydrolase |
Biological process | Gluconeogenesis |
Enzyme and pathway databases
BioCyci | MetaCyc:HS13873-MONOMER |
BRENDAi | 3.1.3.9, 2681 |
PathwayCommonsi | Q9BUM1 |
Reactomei | R-HSA-3282872, Severe congenital neutropenia type 4 (G6PC3) R-HSA-70263, Gluconeogenesis |
SABIO-RKi | Q9BUM1 |
UniPathwayi | UPA00138 |
Names & Taxonomyi
Protein namesi | Recommended name: Glucose-6-phosphatase 3 (EC:3.1.3.9)Short name: G-6-Pase 3 Short name: G6Pase 3 Alternative name(s): Glucose-6-phosphatase beta Short name: G6Pase-beta Ubiquitous glucose-6-phosphatase catalytic subunit-related protein |
Gene namesi | Name:G6PC3 Synonyms:UGRP |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000141349.8 |
HGNCi | HGNC:24861, G6PC3 |
MIMi | 611045, gene |
neXtProti | NX_Q9BUM1 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: HPA
- endoplasmic reticulum membrane Source: Reactome
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 24 | LumenalSequence analysisAdd BLAST | 24 | |
Transmembranei | 25 – 45 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 46 – 54 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 76 – 114 | LumenalSequence analysisAdd BLAST | 39 | |
Transmembranei | 115 – 135 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 136 – 146 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 147 – 164 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 165 – 169 | LumenalSequence analysis | 5 | |
Transmembranei | 170 – 186 | HelicalSequence analysisAdd BLAST | 17 | |
Topological domaini | 187 – 197 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 198 – 218 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 219 – 254 | LumenalSequence analysisAdd BLAST | 36 | |
Transmembranei | 255 – 273 | HelicalSequence analysisAdd BLAST | 19 | |
Topological domaini | 274 – 283 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 305 – 307 | LumenalSequence analysis | 3 | |
Transmembranei | 308 – 328 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 329 – 346 | CytoplasmicSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePathology & Biotechi
Involvement in diseasei
Neutropenia, severe congenital 4, autosomal recessive (SCN4)10 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA disorder of hematopoiesis characterized by maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_073174 | 44 | P → L in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs762019955Ensembl. | 1 | |
Natural variantiVAR_072753 | 44 | P → S in SCN4; complete loss of activity; purified neutrophils from patients have higher levels of spontaneous and staurosporine-induced apoptosis than controls. 3 PublicationsCorresponds to variant dbSNP:rs775224457EnsemblClinVar. | 1 | |
Natural variantiVAR_072754 | 59 | W → R in SCN4. 1 PublicationCorresponds to variant dbSNP:rs752966267Ensembl. | 1 | |
Natural variantiVAR_072755 | 64 – 70 | Missing in SCN4; purified neutrophils from patients have higher levels of spontaneous and staurosporine-induced apoptosis than controls. 1 Publication | 7 | |
Natural variantiVAR_073175 | 116 | M → I in SCN4; complete loss of activity. 1 PublicationCorresponds to variant dbSNP:rs1373865222Ensembl. | 1 | |
Natural variantiVAR_064508 | 116 | M → K in SCN4; the patient also carries mutation Thr-166 in ELANE; complete loss of activity. 3 Publications | 1 | |
Natural variantiVAR_072756 | 116 | M → T in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_064509 | 116 | M → V in DURSS and SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs267606834EnsemblClinVar. | 1 | |
Natural variantiVAR_073176 | 118 | T → R in SCN4; complete loss of activity. 1 PublicationCorresponds to variant dbSNP:rs766706036Ensembl. | 1 | |
Natural variantiVAR_072757 | 139 | S → I in SCN4; partial loss of activity. 2 Publications | 1 | |
Natural variantiVAR_072758 | 154 | L → P in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_073177 | 161 | R → Q in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs1485073209Ensembl. | 1 | |
Natural variantiVAR_055156 | 185 | L → P in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs118203969EnsemblClinVar. | 1 | |
Natural variantiVAR_064510 | 189 | R → Q in SCN4; partial loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs140294222EnsemblClinVar. | 1 | |
Natural variantiVAR_072759 | 208 | L → R in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_073178 | 253 | R → C in SCN4. 1 PublicationCorresponds to variant dbSNP:rs765927570Ensembl. | 1 | |
Natural variantiVAR_055157 | 253 | R → H in SCN4; complete loss of activity; peripheral-blood patient neutrophils have an increased rate of spontaneous apoptosis; transmission electron microscopy of patient bone marrow cells shows an enlarged rough endoplasmic reticulum in myeloid progenitor cells consistent with increased ER stress. 3 PublicationsCorresponds to variant dbSNP:rs118203968EnsemblClinVar. | 1 | |
Natural variantiVAR_072760 | 260 | G → D in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_064511 | 260 | G → R in SCN4; complete loss of activity. 4 PublicationsCorresponds to variant dbSNP:rs200478425EnsemblClinVar. | 1 | |
Natural variantiVAR_055158 | 262 | G → R in SCN4. 1 PublicationCorresponds to variant dbSNP:rs118203971Ensembl. | 1 | |
Natural variantiVAR_072761 | 325 | L → R in SCN4. 1 Publication | 1 |
Dursun syndrome (DURSS)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA disease characterized by pulmonary arterial hypertension, cardiac abnormalities including secundum-type atrial septal defect, intermittent neutropenia, lymphopenia, monocytosis and anemia.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_064509 | 116 | M → V in DURSS and SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs267606834EnsemblClinVar. | 1 |
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 79 | R → A: Loss of catalytic activity. 1 Publication | 1 | |
Mutagenesisi | 114 | H → A: Loss of catalytic activity. 1 Publication | 1 | |
Mutagenesisi | 167 | H → A: Loss of catalytic activity. 1 Publication | 1 |
Keywords - Diseasei
Disease mutationOrganism-specific databases
DisGeNETi | 92579 |
GeneReviewsi | G6PC3 |
MalaCardsi | G6PC3 |
MIMi | 612541, phenotype |
OpenTargetsi | ENSG00000141349 |
Orphaneti | 331176, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
PharmGKBi | PA134968446 |
Miscellaneous databases
Pharosi | Q9BUM1, Tbio |
Polymorphism and mutation databases
BioMutai | G6PC3 |
DMDMi | 74733234 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000334512 | 1 – 346 | Glucose-6-phosphatase 3Add BLAST | 346 |
Proteomic databases
EPDi | Q9BUM1 |
jPOSTi | Q9BUM1 |
MassIVEi | Q9BUM1 |
MaxQBi | Q9BUM1 |
PaxDbi | Q9BUM1 |
PeptideAtlasi | Q9BUM1 |
PRIDEi | Q9BUM1 |
ProteomicsDBi | 79110 |
PTM databases
DEPODi | G6PC3 |
iPTMneti | Q9BUM1 |
PhosphoSitePlusi | Q9BUM1 |
SwissPalmi | Q9BUM1 |
Expressioni
Tissue specificityi
Ubiquitously expressed. Highly expressed in skeletal muscle, at intermediate levels in heart, brain, placenta, kidney, colon, thymus, spleen and pancreas. Also detected in testis, prostate, ovary, liver, lung, small intestine and peripheral blood lymphocytes.3 Publications
Gene expression databases
Bgeei | ENSG00000141349, Expressed in adenohypophysis and 233 other tissues |
ExpressionAtlasi | Q9BUM1, baseline and differential |
Genevisiblei | Q9BUM1, HS |
Organism-specific databases
HPAi | ENSG00000141349, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 124957, 1 interactor |
IntActi | Q9BUM1, 4 interactors |
MINTi | Q9BUM1 |
STRINGi | 9606.ENSP00000269097 |
Miscellaneous databases
RNActi | Q9BUM1, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the glucose-6-phosphatase family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QS5D, Eukaryota |
GeneTreei | ENSGT00950000183150 |
InParanoidi | Q9BUM1 |
OMAi | WSINLAS |
OrthoDBi | 743717at2759 |
PhylomeDBi | Q9BUM1 |
TreeFami | TF324388 |
Family and domain databases
InterProi | View protein in InterPro IPR016275, Glucose-6-phosphatase IPR036938, P_Acid_Pase_2/haloperoxi_sf IPR000326, P_Acid_Pase_2/haloperoxidase |
Pfami | View protein in Pfam PF01569, PAP2, 1 hit |
PIRSFi | PIRSF000905, Glucose-6-phosphatase, 1 hit |
SMARTi | View protein in SMART SM00014, acidPPc, 1 hit |
SUPFAMi | SSF48317, SSF48317, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q9BUM1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESTLGAGIV IAEALQNQLA WLENVWLWIT FLGDPKILFL FYFPAAYYAS
60 70 80 90 100
RRVGIAVLWI SLITEWLNLI FKWFLFGDRP FWWVHESGYY SQAPAQVHQF
110 120 130 140 150
PSSCETGPGS PSGHCMITGA ALWPIMTALS SQVATRARSR WVRVMPSLAY
160 170 180 190 200
CTFLLAVGLS RIFILAHFPH QVLAGLITGA VLGWLMTPRV PMERELSFYG
210 220 230 240 250
LTALALMLGT SLIYWTLFTL GLDLSWSISL AFKWCERPEW IHVDSRPFAS
260 270 280 290 300
LSRDSGAALG LGIALHSPCY AQVRRAQLGN GQKIACLVLA MGLLGPLDWL
310 320 330 340
GHPPQISLFY IFNFLKYTLW PCLVLALVPW AVHMFSAQEA PPIHSS
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketK7ESE6 | K7ESE6_HUMAN | Glucose-6-phosphatase 3 | G6PC3 | 243 | Annotation score: | ||
K7EQ13 | K7EQ13_HUMAN | Glucose-6-phosphatase 3 | G6PC3 | 72 | Annotation score: | ||
K7ENK1 | K7ENK1_HUMAN | Glucose-6-phosphatase 3 | G6PC3 | 73 | Annotation score: | ||
K7EJC5 | K7EJC5_HUMAN | Glucose-6-phosphatase 3 | G6PC3 | 69 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_073174 | 44 | P → L in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs762019955Ensembl. | 1 | |
Natural variantiVAR_072753 | 44 | P → S in SCN4; complete loss of activity; purified neutrophils from patients have higher levels of spontaneous and staurosporine-induced apoptosis than controls. 3 PublicationsCorresponds to variant dbSNP:rs775224457EnsemblClinVar. | 1 | |
Natural variantiVAR_072754 | 59 | W → R in SCN4. 1 PublicationCorresponds to variant dbSNP:rs752966267Ensembl. | 1 | |
Natural variantiVAR_072755 | 64 – 70 | Missing in SCN4; purified neutrophils from patients have higher levels of spontaneous and staurosporine-induced apoptosis than controls. 1 Publication | 7 | |
Natural variantiVAR_073175 | 116 | M → I in SCN4; complete loss of activity. 1 PublicationCorresponds to variant dbSNP:rs1373865222Ensembl. | 1 | |
Natural variantiVAR_064508 | 116 | M → K in SCN4; the patient also carries mutation Thr-166 in ELANE; complete loss of activity. 3 Publications | 1 | |
Natural variantiVAR_072756 | 116 | M → T in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_064509 | 116 | M → V in DURSS and SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs267606834EnsemblClinVar. | 1 | |
Natural variantiVAR_073176 | 118 | T → R in SCN4; complete loss of activity. 1 PublicationCorresponds to variant dbSNP:rs766706036Ensembl. | 1 | |
Natural variantiVAR_072757 | 139 | S → I in SCN4; partial loss of activity. 2 Publications | 1 | |
Natural variantiVAR_072758 | 154 | L → P in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_073177 | 161 | R → Q in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs1485073209Ensembl. | 1 | |
Natural variantiVAR_055156 | 185 | L → P in SCN4; complete loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs118203969EnsemblClinVar. | 1 | |
Natural variantiVAR_064510 | 189 | R → Q in SCN4; partial loss of activity. 2 PublicationsCorresponds to variant dbSNP:rs140294222EnsemblClinVar. | 1 | |
Natural variantiVAR_072759 | 208 | L → R in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_043378 | 216 | T → I. Corresponds to variant dbSNP:rs34406052EnsemblClinVar. | 1 | |
Natural variantiVAR_073178 | 253 | R → C in SCN4. 1 PublicationCorresponds to variant dbSNP:rs765927570Ensembl. | 1 | |
Natural variantiVAR_055157 | 253 | R → H in SCN4; complete loss of activity; peripheral-blood patient neutrophils have an increased rate of spontaneous apoptosis; transmission electron microscopy of patient bone marrow cells shows an enlarged rough endoplasmic reticulum in myeloid progenitor cells consistent with increased ER stress. 3 PublicationsCorresponds to variant dbSNP:rs118203968EnsemblClinVar. | 1 | |
Natural variantiVAR_072760 | 260 | G → D in SCN4; complete loss of activity. 2 Publications | 1 | |
Natural variantiVAR_064511 | 260 | G → R in SCN4; complete loss of activity. 4 PublicationsCorresponds to variant dbSNP:rs200478425EnsemblClinVar. | 1 | |
Natural variantiVAR_055158 | 262 | G → R in SCN4. 1 PublicationCorresponds to variant dbSNP:rs118203971Ensembl. | 1 | |
Natural variantiVAR_072761 | 325 | L → R in SCN4. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471178 Genomic DNA Translation: EAW51638.1 BC002494 mRNA Translation: AAH02494.2 BC021574 mRNA Translation: AAH21574.1 |
CCDSi | CCDS11476.1 |
RefSeqi | NP_612396.1, NM_138387.3 |
Genome annotation databases
Ensembli | ENST00000269097; ENSP00000269097; ENSG00000141349 |
GeneIDi | 92579 |
KEGGi | hsa:92579 |
UCSCi | uc002iex.4, human |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471178 Genomic DNA Translation: EAW51638.1 BC002494 mRNA Translation: AAH02494.2 BC021574 mRNA Translation: AAH21574.1 |
CCDSi | CCDS11476.1 |
RefSeqi | NP_612396.1, NM_138387.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 124957, 1 interactor |
IntActi | Q9BUM1, 4 interactors |
MINTi | Q9BUM1 |
STRINGi | 9606.ENSP00000269097 |
PTM databases
DEPODi | G6PC3 |
iPTMneti | Q9BUM1 |
PhosphoSitePlusi | Q9BUM1 |
SwissPalmi | Q9BUM1 |
Polymorphism and mutation databases
BioMutai | G6PC3 |
DMDMi | 74733234 |
Proteomic databases
EPDi | Q9BUM1 |
jPOSTi | Q9BUM1 |
MassIVEi | Q9BUM1 |
MaxQBi | Q9BUM1 |
PaxDbi | Q9BUM1 |
PeptideAtlasi | Q9BUM1 |
PRIDEi | Q9BUM1 |
ProteomicsDBi | 79110 |
Protocols and materials databases
Antibodypediai | 59289, 74 antibodies |
Genome annotation databases
Ensembli | ENST00000269097; ENSP00000269097; ENSG00000141349 |
GeneIDi | 92579 |
KEGGi | hsa:92579 |
UCSCi | uc002iex.4, human |
Organism-specific databases
CTDi | 92579 |
DisGeNETi | 92579 |
EuPathDBi | HostDB:ENSG00000141349.8 |
GeneCardsi | G6PC3 |
GeneReviewsi | G6PC3 |
HGNCi | HGNC:24861, G6PC3 |
HPAi | ENSG00000141349, Low tissue specificity |
MalaCardsi | G6PC3 |
MIMi | 611045, gene 612541, phenotype |
neXtProti | NX_Q9BUM1 |
OpenTargetsi | ENSG00000141349 |
Orphaneti | 331176, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
PharmGKBi | PA134968446 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QS5D, Eukaryota |
GeneTreei | ENSGT00950000183150 |
InParanoidi | Q9BUM1 |
OMAi | WSINLAS |
OrthoDBi | 743717at2759 |
PhylomeDBi | Q9BUM1 |
TreeFami | TF324388 |
Enzyme and pathway databases
UniPathwayi | UPA00138 |
BioCyci | MetaCyc:HS13873-MONOMER |
BRENDAi | 3.1.3.9, 2681 |
PathwayCommonsi | Q9BUM1 |
Reactomei | R-HSA-3282872, Severe congenital neutropenia type 4 (G6PC3) R-HSA-70263, Gluconeogenesis |
SABIO-RKi | Q9BUM1 |
Miscellaneous databases
BioGRID-ORCSi | 92579, 1 hit in 843 CRISPR screens |
ChiTaRSi | G6PC3, human |
GeneWikii | G6PC3 |
GenomeRNAii | 92579 |
Pharosi | Q9BUM1, Tbio |
PROi | PR:Q9BUM1 |
RNActi | Q9BUM1, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000141349, Expressed in adenohypophysis and 233 other tissues |
ExpressionAtlasi | Q9BUM1, baseline and differential |
Genevisiblei | Q9BUM1, HS |
Family and domain databases
InterProi | View protein in InterPro IPR016275, Glucose-6-phosphatase IPR036938, P_Acid_Pase_2/haloperoxi_sf IPR000326, P_Acid_Pase_2/haloperoxidase |
Pfami | View protein in Pfam PF01569, PAP2, 1 hit |
PIRSFi | PIRSF000905, Glucose-6-phosphatase, 1 hit |
SMARTi | View protein in SMART SM00014, acidPPc, 1 hit |
SUPFAMi | SSF48317, SSF48317, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G6PC3_HUMAN | |
Accessioni | Q9BUM1Primary (citable) accession number: Q9BUM1 Secondary accession number(s): Q8WU15 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 20, 2008 |
Last sequence update: | March 1, 2004 | |
Last modified: | December 2, 2020 | |
This is version 158 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families - Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations