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UniProtKB - Q9BTM9 (URM1_HUMAN)

Entry version 152 (07 Apr 2021)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

Ubiquitin-related modifier 1

Gene

URM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.UniRule annotation2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis

This protein is involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis, which is part of tRNA modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis and in tRNA modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processtRNA processing, Ubl conjugation pathway

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:ENSG00000167118-MONOMER

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BTM9

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6782315, tRNA modification in the nucleus and cytosol

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00988

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquitin-related modifier 1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:URM1UniRule annotation
Synonyms:C9orf74
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28378, URM1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		612693, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BTM9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000167118.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		81605

Open Targets

More...OpenTargetsi		ENSG00000167118

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162408677

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BTM9, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		URM1

Domain mapping of disease mutations (DMDM)

More...DMDMi		68565265

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000897141 – 101Ubiquitin-related modifier 1Add BLAST101

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1011-thioglycineUniRule annotation1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki101Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.UniRule annotation1 Publication

Keywords - PTMi

Isopeptide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BTM9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BTM9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BTM9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BTM9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BTM9

PeptideAtlas

More...PeptideAtlasi		Q9BTM9

PRoteomics IDEntifications database

More...PRIDEi		Q9BTM9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78999 [Q9BTM9-1]
79000 [Q9BTM9-2]

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q9BTM9-1 [Q9BTM9-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BTM9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BTM9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000167118, Expressed in endometrium epithelium and 230 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BTM9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BTM9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000167118, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.

UniRule annotation1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123542, 20 interactors

Database of interacting proteins

More...DIPi		DIP-48631N

Protein interaction database and analysis system

More...IntActi		Q9BTM9, 27 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000412922

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BTM9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BTM9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the URM1 family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4146, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000005101

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_148208_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BTM9

Identification of Orthologs from Complete Genome Data

More...OMAi		EMLFSDQ

Database of Orthologous Groups

More...OrthoDBi		1389193at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BTM9

TreeFam database of animal gene trees

More...TreeFami		TF336363

Family and domain databases

Conserved Domains Database

More...CDDi		cd01764, Ubl_Urm1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.20.30, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_03048, Urm1, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012675, Beta-grasp_dom_sf
IPR016155, Mopterin_synth/thiamin_S_b
IPR015221, Urm1

The PANTHER Classification System

More...PANTHERi		PTHR14986, PTHR14986, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09138, Urm1, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF037379, Ubiquitin-related_modifier_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54285, SSF54285, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BTM9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL 
        60         70         80         90        100
KERPELFIQG DSVRPGILVL INDADWELLG ELDYQLQDQD SVLFISTLHG 

G
Length:101
Mass (Da):11,380
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8DE9B11957866155
GO
Isoform 2 (identifier: Q9BTM9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     79-101: LGELDYQLQDQDSVLFISTLHGG → LVSTLGDIPP...SWGHGSTPPS

Show »
Length:146
Mass (Da):15,815
Checksum:iC52CEFA6A2E72779
GO
Isoform 3 (identifier: Q9BTM9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     64-101: Missing.

Show »
Length:63
Mass (Da):7,143
Checksum:i96BA93664527546A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T4A9Q5T4A9_HUMAN
Ubiquitin-related modifier 1
URM1
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05429664 – 101Missing in isoform 3. CuratedAdd BLAST38
Alternative sequenceiVSP_04002679 – 101LGELD…TLHGG → LVSTLGDIPPPAPALAASVG KRWASPQAHIEWLGNPPPHS SPTLRLLESPTPGEEGMGSW GHGSTPPS in isoform 2. 1 PublicationAdd BLAST23

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK001880 mRNA Translation: BAG50985.1
AK300877 mRNA Translation: BAG62520.1
AL359091 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87782.1
BC003581 mRNA Translation: AAH03581.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS48035.1 [Q9BTM9-2]
CCDS59148.1 [Q9BTM9-3]
CCDS6900.1 [Q9BTM9-1]

NCBI Reference Sequences

More...RefSeqi		NP_001129419.1, NM_001135947.2 [Q9BTM9-2]
NP_001252511.1, NM_001265582.1 [Q9BTM9-3]
NP_112176.1, NM_030914.3 [Q9BTM9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000372850; ENSP00000361941; ENSG00000167118 [Q9BTM9-3]
ENST00000372853; ENSP00000361944; ENSG00000167118 [Q9BTM9-1]
ENST00000483206; ENSP00000501135; ENSG00000167118 [Q9BTM9-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		81605

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:81605

UCSC genome browser

More...UCSCi		uc004buv.3, human [Q9BTM9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001880 mRNA Translation: BAG50985.1
AK300877 mRNA Translation: BAG62520.1
AL359091 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87782.1
BC003581 mRNA Translation: AAH03581.1
CCDSiCCDS48035.1 [Q9BTM9-2]
CCDS59148.1 [Q9BTM9-3]
CCDS6900.1 [Q9BTM9-1]
RefSeqiNP_001129419.1, NM_001135947.2 [Q9BTM9-2]
NP_001252511.1, NM_001265582.1 [Q9BTM9-3]
NP_112176.1, NM_030914.3 [Q9BTM9-1]

3D structure databases

SMRiQ9BTM9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123542, 20 interactors
DIPiDIP-48631N
IntActiQ9BTM9, 27 interactors
STRINGi9606.ENSP00000412922

PTM databases

iPTMnetiQ9BTM9
PhosphoSitePlusiQ9BTM9

Genetic variation databases

BioMutaiURM1
DMDMi68565265

Proteomic databases

EPDiQ9BTM9
jPOSTiQ9BTM9
MassIVEiQ9BTM9
MaxQBiQ9BTM9
PaxDbiQ9BTM9
PeptideAtlasiQ9BTM9
PRIDEiQ9BTM9
ProteomicsDBi78999 [Q9BTM9-1]
79000 [Q9BTM9-2]
TopDownProteomicsiQ9BTM9-1 [Q9BTM9-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		17464, 128 antibodies

Genome annotation databases

EnsembliENST00000372850; ENSP00000361941; ENSG00000167118 [Q9BTM9-3]
ENST00000372853; ENSP00000361944; ENSG00000167118 [Q9BTM9-1]
ENST00000483206; ENSP00000501135; ENSG00000167118 [Q9BTM9-2]
GeneIDi81605
KEGGihsa:81605
UCSCiuc004buv.3, human [Q9BTM9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		81605
DisGeNETi81605

GeneCards: human genes, protein and diseases

More...GeneCardsi		URM1
HGNCiHGNC:28378, URM1
HPAiENSG00000167118, Low tissue specificity
MIMi612693, gene
neXtProtiNX_Q9BTM9
OpenTargetsiENSG00000167118
PharmGKBiPA162408677
VEuPathDBiHostDB:ENSG00000167118.10

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4146, Eukaryota
GeneTreeiENSGT00390000005101
HOGENOMiCLU_148208_0_1_1
InParanoidiQ9BTM9
OMAiEMLFSDQ
OrthoDBi1389193at2759
PhylomeDBiQ9BTM9
TreeFamiTF336363

Enzyme and pathway databases

UniPathwayiUPA00988
BioCyciMetaCyc:ENSG00000167118-MONOMER
PathwayCommonsiQ9BTM9
ReactomeiR-HSA-6782315, tRNA modification in the nucleus and cytosol

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		81605, 491 hits in 1009 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		URM1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		81605
PharosiQ9BTM9, Tbio

Protein Ontology

More...PROi		PR:Q9BTM9
RNActiQ9BTM9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000167118, Expressed in endometrium epithelium and 230 other tissues
ExpressionAtlasiQ9BTM9, baseline and differential
GenevisibleiQ9BTM9, HS

Family and domain databases

CDDicd01764, Ubl_Urm1, 1 hit
Gene3Di3.10.20.30, 1 hit
HAMAPiMF_03048, Urm1, 1 hit
InterProiView protein in InterPro
IPR012675, Beta-grasp_dom_sf
IPR016155, Mopterin_synth/thiamin_S_b
IPR015221, Urm1
PANTHERiPTHR14986, PTHR14986, 1 hit
PfamiView protein in Pfam
PF09138, Urm1, 1 hit
PIRSFiPIRSF037379, Ubiquitin-related_modifier_1, 1 hit
SUPFAMiSSF54285, SSF54285, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiURM1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BTM9
Secondary accession number(s): B3KMH3, B4DV08, Q5T4B4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: June 1, 2001
Last modified: April 7, 2021
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. SIMILARITY comments
    Index of protein domains and families
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