AARSD1

Functionⁱ

Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).By similarity

Cofactorⁱ

Zn²⁺CuratedNote: Binds 1 zinc ion per subunit.Curated

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	109	ZincSequence analysis	1
Metal bindingⁱ	113	ZincSequence analysis	1
Metal bindingⁱ	209	ZincSequence analysis	1
Metal bindingⁱ	213	ZincSequence analysis	1

GO - Molecular functionⁱ

alanine-tRNA ligase activity Source: InterPro
ATP binding Source: InterPro
metal ion binding Source: UniProtKB-KW
nucleic acid binding Source: InterPro
Ser-tRNA(Ala) hydrolase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

alanyl-tRNA aminoacylation Source: InterPro
regulation of translational fidelity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Protein biosynthesis
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Alanyl-tRNA editing protein Aarsd1 Alternative name(s): Alanyl-tRNA synthetase domain-containing protein 1
Gene namesⁱ	Name:AARSD1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 17

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000108825.17 HostDB:ENSG00000266967.6
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28417 AARSD1 HGNC:43946 PTGES3L-AARSD1
MIMⁱ	613212 gene
neXtProtⁱ	NX_Q9BTE6

Keywords - Cellular componentⁱ

Cytoplasm

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000108825 ENSG00000266967
PharmGKBⁱ	PA142670464

Polymorphism and mutation databases

BioMutaⁱ	AARSD1
DMDMⁱ	125987702

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000277465	1 – 412	Alanyl-tRNA editing protein Aarsd1Add BLAST		412

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	174	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	Q9BTE6
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9BTE6
PaxDbⁱ	Q9BTE6
PeptideAtlas More...PeptideAtlasⁱ	Q9BTE6
PRIDEⁱ	Q9BTE6
ProteomicsDBⁱ	78985 78986 [Q9BTE6-2] 78987 [Q9BTE6-3]

2D gel databases

REPRODUCTION-2DPAGE More...REPRODUCTION-2DPAGEⁱ	IPI00827636

REPRODUCTION-2DPAGEⁱ

IPI00827636

PTM databases

iPTMnetⁱ	Q9BTE6
PhosphoSitePlusⁱ	Q9BTE6

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000108825 Expressed in 91 organ(s), highest expression level in testis
CleanExⁱ	HS_AARSD1
ExpressionAtlasⁱ	Q9BTE6 baseline and differential
Genevisibleⁱ	Q9BTE6 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA021408 HPA022869 HPA023714

HPAⁱ

HPA021408
HPA022869
HPA023714

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
	Q96BE0	2	EBI-9357295,EBI-9356686

With

Entry

#Exp.

IntAct

Notes

Q96BE0

2

EBI-9357295,EBI-9356686

Protein-protein interaction databases

BioGridⁱ	123290, 97 interactors 3190353, 7 interactors
IntActⁱ	Q9BTE6, 125 interactors
STRINGⁱ	9606.ENSP00000386621

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9BTE6
SMRⁱ	Q9BTE6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.Curated

Phylogenomic databases

eggNOGⁱ	KOG2105 Eukaryota KOG3158 Eukaryota COG2872 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00510000046493
HOGENOMⁱ	HOG000230967
HOVERGENⁱ	HBG080017
InParanoidⁱ	Q9BTE6
KEGG Orthology (KO) More...KOⁱ	K07050
OMAⁱ	DREFKYD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0K2Q
PhylomeDBⁱ	Q9BTE6
TreeFamⁱ	TF323735

Family and domain databases

InterProⁱ	View protein in InterPro IPR018165 Ala-tRNA-synth_IIc_core IPR018164 Ala-tRNA-synth_IIc_N IPR018163 Thr/Ala-tRNA-synth_IIc_edit IPR009000 Transl_B-barrel_sf IPR012947 tRNA_SAD
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01411 tRNA-synt_2c, 1 hit PF07973 tRNA_SAD, 1 hit
SMARTⁱ	View protein in SMART SM00863 tRNA_SAD, 1 hit
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF55186 SSF55186, 1 hit
PROSITEⁱ	View protein in PROSITE PS50860 AA_TRNA_LIGASE_II_ALA, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 9 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9BTE6-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAFWCQRDSY AREFTTTVVS CCPAELQTEG SNGKKEVLSG FQVVLEDTVL 
        60         70         80         90        100
FPEGGGQPDD RGTINDISVL RVTRRGEQAD HFTQTPLDPG SQVLVRVDWE 
       110        120        130        140        150
RRFDHMQQHS GQHLITAVAD HLFKLKTTSW ELGRFRSAIE LDTPSMTAEQ 
       160        170        180        190        200
VAAIEQSVNE KIRDRLPVNV RELSLDDPEV EQVSGRGLPD DHAGPIRVVN 
       210        220        230        240        250
IEGVDSNMCC GTHVSNLSDL QVIKILGTEK GKKNRTNLIF LSGNRVLKWM 
       260        270        280        290        300
ERSHGTEKAL TALLKCGAED HVEAVKKLQN STKILQKNNL NLLRDLAVHI 
       310        320        330        340        350
AHSLRNSPDW GGVVILHRKE GDSEFMNIIA NEIGSEETLL FLTVGDEKGG 
       360        370        380        390        400
GLFLLAGPPA SVETLGPRVA EVLEGKGAGK KGRFQGKATK MSRRMEAQAL 
       410 
LQDYISTQSA KE

Length:412

Mass (Da):45,480

Last modified:February 6, 2007 - v2

Checksum:ⁱ2E14B6274C6EF897

GO

Isoform 2 (identifier: Q9BTE6-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-13: MAFWCQRDSYARE → MEFCVEDSTD...RPPPAMDDLD

« Hide

        10         20         30         40         50
MEFCVEDSTD VHVLIEDHRI VFSCKNADGV ELYNEIEFYA KVNSKDSQDK 
        60         70         80         90        100
RSSRSITCFV RKWKEKVAWP RLTKEDIKPV WLSVDFDNWR DWEGDEEMEL 
       110        120        130        140        150
AHVEHYAELL KKVSTKRPPP AMDDLDFTTT VVSCCPAELQ TEGSNGKKEV 
       160        170        180        190        200
LSGFQVVLED TVLFPEGGGQ PDDRGTINDI SVLRVTRRGE QADHFTQTPL 
       210        220        230        240        250
DPGSQVLVRV DWERRFDHMQ QHSGQHLITA VADHLFKLKT TSWELGRFRS 
       260        270        280        290        300
AIELDTPSMT AEQVAAIEQS VNEKIRDRLP VNVRELSLDD PEVEQVSGRG 
       310        320        330        340        350
LPDDHAGPIR VVNIEGVDSN MCCGTHVSNL SDLQVIKILG TEKGKKNRTN 
       360        370        380        390        400
LIFLSGNRVL KWMERSHGTE KALTALLKCG AEDHVEAVKK LQNSTKILQK 
       410        420        430        440        450
NNLNLLRDLA VHIAHSLRNS PDWGGVVILH RKEGDSEFMN IIANEIGSEE 
       460        470        480        490        500
TLLFLTVGDE KGGGLFLLAG PPASVETLGP RVAEVLEGKG AGKKGRFQGK 
       510        520 
ATKMSRRMEA QALLQDYIST QSAKE

Note: Based on a readthrough transcript which may produce a PTGES3L-AARSD1 fusion protein. No experimental confirmation available.

Show »

Length:525

Mass (Da):58,753

Checksum:ⁱ04F376DFD308BC68

GO

Isoform 3 (identifier: Q9BTE6-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-13: MAFWCQRDSYARE → MFSLPLNCSP...RPPPAMDDLD

« Hide

        10         20         30         40         50
MFSLPLNCSP DHIRRGSCWG RPQDLKIAAP AWNSKCHPGA GAAMARQHAR 
        60         70         80         90        100
TLWYDRPRYV FMEFCVEDST DVHVLIEDHR IVFSCKNADG VELYNEIEFY 
       110        120        130        140        150
AKVNSKDSQD KRSSRSITCF VRKWKEKVAW PRLTKEDIKP VWLSVDFDNW 
       160        170        180        190        200
RDWEGDEEME LAHVEHYAEL LKKVSTKRPP PAMDDLDFTT TVVSCCPAEL 
       210        220        230        240        250
QTEGSNGKKE VLSGFQVVLE DTVLFPEGGG QPDDRGTIND ISVLRVTRRG 
       260        270        280        290        300
EQADHFTQTP LDPGSQVLVR VDWERRFDHM QQHSGQHLIT AVADHLFKLK 
       310        320        330        340        350
TTSWELGRFR SAIELDTPSM TAEQVAAIEQ SVNEKIRDRL PVNVRELSLD 
       360        370        380        390        400
DPEVEQVSGR GLPDDHAGPI RVVNIEGVDS NMCCGTHVSN LSDLQVIKIL 
       410        420        430        440        450
GTEKGKKNRT NLIFLSGNRV LKWMERSHGT EKALTALLKC GAEDHVEAVK 
       460        470        480        490        500
KLQNSTKILQ KNNLNLLRDL AVHIAHSLRN SPDWGGVVIL HRKEGDSEFM 
       510        520        530        540        550
NIIANEIGSE ETLLFLTVGD EKGGGLFLLA GPPASVETLG PRVAEVLEGK 
       560        570        580 
GAGKKGRFQG KATKMSRRME AQALLQDYIS TQSAKE

Note: Based on a readthrough transcript which may produce a PTGES3L-AARSD1 fusion protein. No experimental confirmation available.

Show »

Length:586

Mass (Da):65,702

Checksum:ⁱBA9D4A890AA69180

GO

Computationally mapped potential isoform sequencesⁱ

There are 9 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

C9J5N1	C9J5N1_HUMAN	PTGES3L-AARSD1 readthrough PTGES3L-AARSD1 readthrough	PTGES3L-AARSD1	495	Annotation score:
L7N2F4	L7N2F4_HUMAN	Alanyl-tRNA-editing protein Aarsd1 Alanyl-tRNA-editing protein Aarsd1	AARSD1	140	Annotation score:
H7C054	H7C054_HUMAN	PTGES3L-AARSD1 readthrough PTGES3L-AARSD1 readthrough	PTGES3L-AARSD1	189	Annotation score:
K7N799	K7N799_HUMAN	Alanyl-tRNA-editing protein Aarsd1 Alanyl-tRNA-editing protein Aarsd1	AARSD1	84	Annotation score:
L7N2F6	L7N2F6_HUMAN	PTGES3L-AARSD1 readthrough PTGES3L-AARSD1 readthrough	PTGES3L-AARSD1	132	Annotation score:
H7C1K1	H7C1K1_HUMAN	Alanyl-tRNA-editing protein Aarsd1 Alanyl-tRNA-editing protein Aarsd1	AARSD1	79	Annotation score:
L7N2F5	L7N2F5_HUMAN	Alanyl-tRNA-editing protein Aarsd1 Alanyl-tRNA-editing protein Aarsd1	AARSD1	98	Annotation score:
K7EQ85	K7EQ85_HUMAN	Alanyl-tRNA-editing protein Aarsd1 Alanyl-tRNA-editing protein Aarsd1	AARSD1	94	Annotation score:
C9JUA3	C9JUA3_HUMAN	PTGES3L-AARSD1 readthrough PTGES3L-AARSD1 readthrough	PTGES3L-AARSD1	53	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_023014	1 – 13	MAFWC…SYARE → MEFCVEDSTDVHVLIEDHRI VFSCKNADGVELYNEIEFYA KVNSKDSQDKRSSRSITCFV RKWKEKVAWPRLTKEDIKPV WLSVDFDNWRDWEGDEEMEL AHVEHYAELLKKVSTKRPPP AMDDLD in isoform 2. 1 PublicationAdd BLAST		13
Alternative sequenceⁱVSP_043142	1 – 13	MAFWC…SYARE → MFSLPLNCSPDHIRRGSCWG RPQDLKIAAPAWNSKCHPGA GAAMARQHARTLWYDRPRYV FMEFCVEDSTDVHVLIEDHR IVFSCKNADGVELYNEIEFY AKVNSKDSQDKRSSRSITCF VRKWKEKVAWPRLTKEDIKP VWLSVDFDNWRDWEGDEEME LAHVEHYAELLKKVSTKRPP PAMDDLD in isoform 3. 1 PublicationAdd BLAST		13

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK295447 mRNA Translation: BAG58385.1 CR608238 mRNA No translation available. AC055866 Genomic DNA No translation available. CH471152 Genomic DNA Translation: EAW60903.1 BC004172 mRNA Translation: AAH04172.1 BC019324 mRNA Translation: AAH19324.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS58552.1 [Q9BTE6-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001129514.2, NM_001136042.2 [Q9BTE6-3] NP_001248363.1, NM_001261434.1 [Q9BTE6-1] NP_079543.1, NM_025267.3 [Q9BTE6-2]
UniGeneⁱ	Hs.317403

Genome annotation databases

Ensemblⁱ	ENST00000360221; ENSP00000353355; ENSG00000108825 [Q9BTE6-2] ENST00000409399; ENSP00000386621; ENSG00000108825 [Q9BTE6-3] ENST00000421990; ENSP00000409924; ENSG00000108825 [Q9BTE6-3] ENST00000427569; ENSP00000400870; ENSG00000266967 [Q9BTE6-1]
GeneIDⁱ	100885850 80755
KEGGⁱ	hsa:100885850 hsa:80755
UCSC genome browser More...UCSCⁱ	uc002icd.3 human [Q9BTE6-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9BTE6	PTGES3L-AARSD1 readthrough		HUMAN		495	UniRef90_Q9BTE6
Uncharacterized protein		PANTR		495
Uncharacterized protein		PANPA		495
Uncharacterized protein		MACMU		494
Uncharacterized protein		MACFA		494
+28
Q9BTE6-2	Predicted gene, 27029		MOUSE		543	UniRef90_A2A4P4
PTGES3L-AARSD1 readthrough		PANTR		586
PTGES3L-AARSD1 readthrough (Fragment)		HUMAN		132
Uncharacterized protein		SHEEP		586
Uncharacterized protein		PANPA		586
+23
Q9BTE6-3	Predicted gene, 27029		MOUSE		543	UniRef90_A2A4P4
PTGES3L-AARSD1 readthrough		PANTR		586
PTGES3L-AARSD1 readthrough (Fragment)		HUMAN		132
Uncharacterized protein		SHEEP		586
Uncharacterized protein		PANPA		586
+23

Protein	Similar proteins		Species	Score	Length	Source
Q9BTE6	Alanyl-tRNA editing protein Aarsd1		MOUSE		412	UniRef50_Q3THG9
Alanyl-tRNA editing protein Aarsd1		RAT		412
Alanyl-tRNA editing protein Aarsd1		MYOBR		456
alanyl-tRNA editing protein Aarsd1		LEPWE		412
alanyl-tRNA editing protein Aarsd1 isoform X1		Florida manatee		412
+125
Q9BTE6-2	Predicted gene, 27029		MOUSE		543	UniRef50_A2A4P4
PTGES3L-AARSD1 readthrough		PANTR		586
PTGES3L-AARSD1 readthrough (Fragment)		HUMAN		132
Uncharacterized protein		SHEEP		586
Uncharacterized protein		PANPA		586
+67
Q9BTE6-3	Predicted gene, 27029		MOUSE		543	UniRef50_A2A4P4
PTGES3L-AARSD1 readthrough		PANTR		586
PTGES3L-AARSD1 readthrough (Fragment)		HUMAN		132
Uncharacterized protein		SHEEP		586
Uncharacterized protein		PANPA		586
+67

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK295447 mRNA Translation: BAG58385.1 CR608238 mRNA No translation available. AC055866 Genomic DNA No translation available. CH471152 Genomic DNA Translation: EAW60903.1 BC004172 mRNA Translation: AAH04172.1 BC019324 mRNA Translation: AAH19324.1
CCDSⁱ	CCDS58552.1 [Q9BTE6-1]
RefSeqⁱ	NP_001129514.2, NM_001136042.2 [Q9BTE6-3] NP_001248363.1, NM_001261434.1 [Q9BTE6-1] NP_079543.1, NM_025267.3 [Q9BTE6-2]
UniGeneⁱ	Hs.317403

3D structure databases

ProteinModelPortalⁱ	Q9BTE6
SMRⁱ	Q9BTE6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	123290, 97 interactors 3190353, 7 interactors
IntActⁱ	Q9BTE6, 125 interactors
STRINGⁱ	9606.ENSP00000386621

PTM databases

iPTMnetⁱ	Q9BTE6
PhosphoSitePlusⁱ	Q9BTE6

Polymorphism and mutation databases

BioMutaⁱ	AARSD1
DMDMⁱ	125987702

2D gel databases

REPRODUCTION-2DPAGEⁱ	IPI00827636

REPRODUCTION-2DPAGEⁱ

IPI00827636

Proteomic databases

EPDⁱ	Q9BTE6
MaxQBⁱ	Q9BTE6
PaxDbⁱ	Q9BTE6
PeptideAtlasⁱ	Q9BTE6
PRIDEⁱ	Q9BTE6
ProteomicsDBⁱ	78985 78986 [Q9BTE6-2] 78987 [Q9BTE6-3]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	80755
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000360221; ENSP00000353355; ENSG00000108825 [Q9BTE6-2] ENST00000409399; ENSP00000386621; ENSG00000108825 [Q9BTE6-3] ENST00000421990; ENSP00000409924; ENSG00000108825 [Q9BTE6-3] ENST00000427569; ENSP00000400870; ENSG00000266967 [Q9BTE6-1]
GeneIDⁱ	100885850 80755
KEGGⁱ	hsa:100885850 hsa:80755
UCSCⁱ	uc002icd.3 human [Q9BTE6-1]

Organism-specific databases

CTDⁱ	100885850 80755
EuPathDBⁱ	HostDB:ENSG00000108825.17 HostDB:ENSG00000266967.6
GeneCardsⁱ	AARSD1 PTGES3L-AARSD1
HGNCⁱ	HGNC:28417 AARSD1 HGNC:43946 PTGES3L-AARSD1
HPAⁱ	HPA021408 HPA022869 HPA023714
MIMⁱ	613212 gene
neXtProtⁱ	NX_Q9BTE6
OpenTargetsⁱ	ENSG00000108825 ENSG00000266967
PharmGKBⁱ	PA142670464
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2105 Eukaryota KOG3158 Eukaryota COG2872 LUCA
GeneTreeⁱ	ENSGT00510000046493
HOGENOMⁱ	HOG000230967
HOVERGENⁱ	HBG080017
InParanoidⁱ	Q9BTE6
KOⁱ	K07050
OMAⁱ	DREFKYD
OrthoDBⁱ	EOG091G0K2Q
PhylomeDBⁱ	Q9BTE6
TreeFamⁱ	TF323735

Miscellaneous databases

ChiTaRSⁱ	AARSD1 human
Protein Ontology More...PROⁱ	PR:Q9BTE6
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000108825 Expressed in 91 organ(s), highest expression level in testis
CleanExⁱ	HS_AARSD1
ExpressionAtlasⁱ	Q9BTE6 baseline and differential
Genevisibleⁱ	Q9BTE6 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR018165 Ala-tRNA-synth_IIc_core IPR018164 Ala-tRNA-synth_IIc_N IPR018163 Thr/Ala-tRNA-synth_IIc_edit IPR009000 Transl_B-barrel_sf IPR012947 tRNA_SAD
Pfamⁱ	View protein in Pfam PF01411 tRNA-synt_2c, 1 hit PF07973 tRNA_SAD, 1 hit
SMARTⁱ	View protein in SMART SM00863 tRNA_SAD, 1 hit
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF55186 SSF55186, 1 hit
PROSITEⁱ	View protein in PROSITE PS50860 AA_TRNA_LIGASE_II_ALA, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	AASD1_HUMAN
Accessionⁱ	Q9BTE6Primary (citable) accession number: Q9BTE6 Secondary accession number(s): B4DI73
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
	Last sequence update:	February 6, 2007
	Last modified:	November 7, 2018
	This is version 144 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM

UniProtKB

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UniProtKB - Q9BTE6 (AASD1_HUMAN)

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Alanyl-tRNA editing protein Aarsd1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ