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UniProtKB - Q9BT43 (RPC7L_HUMAN)

Entry version 142 (25 May 2022)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

DNA-directed RNA polymerase III subunit RPC7-like

Gene

POLR3GL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BT43

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1834949, Cytosolic sensors of pathogen-associated DNA
R-HSA-73780, RNA Polymerase III Chain Elongation
R-HSA-73980, RNA Polymerase III Transcription Termination
R-HSA-749476, RNA Polymerase III Abortive And Retractive Initiation
R-HSA-76061, RNA Polymerase III Transcription Initiation From Type 1 Promoter
R-HSA-76066, RNA Polymerase III Transcription Initiation From Type 2 Promoter
R-HSA-76071, RNA Polymerase III Transcription Initiation From Type 3 Promoter

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9BT43

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA-directed RNA polymerase III subunit RPC7-like
Short name:
RNA polymerase III subunit C7-like
Alternative name(s):
DNA-directed RNA polymerase III subunit G-like
RNA polymerase III 32 kDa beta subunit
Short name:
RPC32-beta1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POLR3GL
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28466, POLR3GL

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		617457, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BT43

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000121851

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Short stature, oligodontia, dysmorphic facies, and motor delay (SOFM)2 Publications
The disease may be caused by variants affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive disorder with phenotypic variability. The main clinical features include endosteal hyperostosis, short stature, oligodontia, mild facial dysmorphisms, and delayed motor development. Some patients show progeroid features.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_085496120 – 218Missing in SOFM; unknown pathological significance; decrease in transcript levels, possibly due to nonsense-mediated mRNA decay. 1 PublicationAdd BLAST99

Keywords - Diseasei

Disease variant, Dwarfism

Organism-specific databases

DisGeNET

More...DisGeNETi		84265

MalaCards human disease database

More...MalaCardsi		POLR3GL
MIMi619234, phenotype

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134921690

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BT43, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		POLR3GL

Domain mapping of disease mutations (DMDM)

More...DMDMi		74733087

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003115901 – 218DNA-directed RNA polymerase III subunit RPC7-likeAdd BLAST218

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BT43

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BT43

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BT43

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BT43

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BT43

PeptideAtlas

More...PeptideAtlasi		Q9BT43

PRoteomics IDEntifications database

More...PRIDEi		Q9BT43

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78950

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BT43

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BT43

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Up-regulated in embryonic stem cells upon retinoic acid-induced differentiation into embroid bodies (at protein level) (PubMed:28494942). No significant changes in mRNA levels between dividing and non-dividing cells, although levels tends to be slightly higher in non-dividing cells (PubMed:20154270, PubMed:24107381).3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000121851, Expressed in gastrocnemius and 116 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BT43, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BT43, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000121851, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Found a trimeric complex with POLR3C and POLR3G (PubMed:24107381). Directly interacts with POLR3C (PubMed:21358628, PubMed:24107381, PubMed:26394183).

By similarity3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123992, 32 interactors

Database of interacting proteins

More...DIPi		DIP-59080N

Protein interaction database and analysis system

More...IntActi		Q9BT43, 28 interactors

Molecular INTeraction database

More...MINTi		Q9BT43

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000358320

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BT43, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9BT43

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BT43

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni133 – 218DisorderedSequence analysisAdd BLAST86

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi133 – 158Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi159 – 197Acidic residuesSequence analysisAdd BLAST39
Compositional biasi204 – 218Acidic residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic RPC7 RNA polymerase subunit family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QUPX, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01040000240524

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BT43

Identification of Orthologs from Complete Genome Data

More...OMAi		DKYNRSE

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BT43

TreeFam database of animal gene trees

More...TreeFami		TF103052

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR024661, RNA_pol_III_Rpc31

The PANTHER Classification System

More...PANTHERi		PTHR15367, PTHR15367, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF11705, RNA_pol_3_Rpc31, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000777, RNA_polIII_C31, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9BT43-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASRGGGRGR GRGQLTFNVE AVGIGKGDAL PPPTLQPSPL FPPLEFRPVP 
        60         70         80         90        100
LPSGEEGEYV LALKQELRGA MRQLPYFIRP AVPKRDVERY SDKYQMSGPI 
       110        120        130        140        150
DNAIDWNPDW RRLPRELKIR VRKLQKERIT ILLPKRPPKT TEDKEETIQK 
       160        170        180        190        200
LETLEKKEEE VTSEEDEEKE EEEEKEEEEE EEYDEEEHEE ETDYIMSYFD 
       210 
NGEDFGGDSD DNMDEAIY
Length:218
Mass (Da):25,334
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01E3B35D7279E43E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6NGX6A6NGX6_HUMAN
DNA-directed RNA polymerase III sub...
POLR3GL
195Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_085496120 – 218Missing in SOFM; unknown pathological significance; decrease in transcript levels, possibly due to nonsense-mediated mRNA decay. 1 PublicationAdd BLAST99

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DQ418461 mRNA Translation: ABD76394.1
AK056984 mRNA Translation: BAB71332.1
BC004355 mRNA Translation: AAH04355.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS72875.1

NCBI Reference Sequences

More...RefSeqi		NP_001317614.1, NM_001330685.1
NP_115681.1, NM_032305.2
XP_005277488.1, XM_005277431.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000369314.2; ENSP00000358320.1; ENSG00000121851.13

Database of genes from NCBI RefSeq genomes

More...GeneIDi		84265

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:84265

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000369314.2; ENSP00000358320.1; NM_032305.3; NP_115681.1

UCSC genome browser

More...UCSCi		uc001enp.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ418461 mRNA Translation: ABD76394.1
AK056984 mRNA Translation: BAB71332.1
BC004355 mRNA Translation: AAH04355.1
CCDSiCCDS72875.1
RefSeqiNP_001317614.1, NM_001330685.1
NP_115681.1, NM_032305.2
XP_005277488.1, XM_005277431.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5AFQX-ray7.00D/E50-134[»]
AlphaFoldDBiQ9BT43
SMRiQ9BT43
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi123992, 32 interactors
DIPiDIP-59080N
IntActiQ9BT43, 28 interactors
MINTiQ9BT43
STRINGi9606.ENSP00000358320

PTM databases

iPTMnetiQ9BT43
PhosphoSitePlusiQ9BT43

Genetic variation databases

BioMutaiPOLR3GL
DMDMi74733087

Proteomic databases

EPDiQ9BT43
jPOSTiQ9BT43
MassIVEiQ9BT43
MaxQBiQ9BT43
PaxDbiQ9BT43
PeptideAtlasiQ9BT43
PRIDEiQ9BT43
ProteomicsDBi78950

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33956, 149 antibodies from 15 providers

The DNASU plasmid repository

More...DNASUi		84265

Genome annotation databases

EnsembliENST00000369314.2; ENSP00000358320.1; ENSG00000121851.13
GeneIDi84265
KEGGihsa:84265
MANE-SelectiENST00000369314.2; ENSP00000358320.1; NM_032305.3; NP_115681.1
UCSCiuc001enp.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		84265
DisGeNETi84265

GeneCards: human genes, protein and diseases

More...GeneCardsi		POLR3GL
HGNCiHGNC:28466, POLR3GL
HPAiENSG00000121851, Low tissue specificity
MalaCardsiPOLR3GL
MIMi617457, gene
619234, phenotype
neXtProtiNX_Q9BT43
PharmGKBiPA134921690
VEuPathDBiHostDB:ENSG00000121851

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QUPX, Eukaryota
GeneTreeiENSGT01040000240524
InParanoidiQ9BT43
OMAiDKYNRSE
PhylomeDBiQ9BT43
TreeFamiTF103052

Enzyme and pathway databases

PathwayCommonsiQ9BT43
ReactomeiR-HSA-1834949, Cytosolic sensors of pathogen-associated DNA
R-HSA-73780, RNA Polymerase III Chain Elongation
R-HSA-73980, RNA Polymerase III Transcription Termination
R-HSA-749476, RNA Polymerase III Abortive And Retractive Initiation
R-HSA-76061, RNA Polymerase III Transcription Initiation From Type 1 Promoter
R-HSA-76066, RNA Polymerase III Transcription Initiation From Type 2 Promoter
R-HSA-76071, RNA Polymerase III Transcription Initiation From Type 3 Promoter
SignaLinkiQ9BT43

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		84265, 13 hits in 1078 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		POLR3GL, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		84265
PharosiQ9BT43, Tdark

Protein Ontology

More...PROi		PR:Q9BT43
RNActiQ9BT43, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000121851, Expressed in gastrocnemius and 116 other tissues
ExpressionAtlasiQ9BT43, baseline and differential
GenevisibleiQ9BT43, HS

Family and domain databases

InterProiView protein in InterPro
IPR024661, RNA_pol_III_Rpc31
PANTHERiPTHR15367, PTHR15367, 1 hit
PfamiView protein in Pfam
PF11705, RNA_pol_3_Rpc31, 1 hit
PIRSFiPIRSF000777, RNA_polIII_C31, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPC7L_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BT43
Secondary accession number(s): B1MVG5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: June 1, 2001
Last modified: May 25, 2022
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
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