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UniProtKB - Q9BSE5 (SPEB_HUMAN)

Entry version 168 (12 Aug 2020)
Sequence version 2 (20 Feb 2007)
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Protein

Agmatinase, mitochondrial

Gene

AGMAT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mn2+PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: putrescine biosynthesis via agmatine pathway

This protein is involved in step 1 of the subpathway that synthesizes putrescine from agmatine.1 Publication
Proteins known to be involved in this subpathway in this organism are:
  1. Agmatinase, mitochondrial (AGMAT)
This subpathway is part of the pathway putrescine biosynthesis via agmatine pathway, which is itself part of Amine and polyamine biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes putrescine from agmatine, the pathway putrescine biosynthesis via agmatine pathway and in Amine and polyamine biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi162Manganese 1PROSITE-ProRule annotation1
Metal bindingi185Manganese 1PROSITE-ProRule annotation1
Metal bindingi185Manganese 2PROSITE-ProRule annotation1
Metal bindingi187Manganese 2PROSITE-ProRule annotation1
Metal bindingi189Manganese 1PROSITE-ProRule annotation1
Metal bindingi276Manganese 1PROSITE-ProRule annotation1
Metal bindingi276Manganese 2PROSITE-ProRule annotation1
Metal bindingi278Manganese 2PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processPutrescine biosynthesis, Spermidine biosynthesis
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:HS04051-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		3.5.3.11, 2681

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BSE5

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-351143, Agmatine biosynthesis

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00534;UER00287

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Agmatinase, mitochondrial (EC:3.5.3.111 Publication)
Alternative name(s):
Agmatine ureohydrolase
Short name:
AUH
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AGMAT
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000116771.5

Human Gene Nomenclature Database

More...HGNCi		HGNC:18407, AGMAT

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		617887, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BSE5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79814

Open Targets

More...OpenTargetsi		ENSG00000116771

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA24619

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BSE5, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		AGMAT

Domain mapping of disease mutations (DMDM)

More...DMDMi		126302602

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 35MitochondrionSequence analysisAdd BLAST35
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000208936 – 352Agmatinase, mitochondrialAdd BLAST317

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei193N6-acetyllysineBy similarity1
Modified residuei217N6-acetyllysine; alternateBy similarity1
Modified residuei217N6-succinyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BSE5

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BSE5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BSE5

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BSE5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BSE5

PeptideAtlas

More...PeptideAtlasi		Q9BSE5

PRoteomics IDEntifications database

More...PRIDEi		Q9BSE5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78882

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BSE5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BSE5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower levels in the medulla and spinal cord.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000116771, Expressed in cortex of kidney and 163 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BSE5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BSE5, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000116771, Tissue enhanced (intestine, kidney, liver)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122909, 28 interactors

Protein interaction database and analysis system

More...IntActi		Q9BSE5, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000364986

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BSE5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BSE5

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the arginase family. Agmatinase subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2964, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183195

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_039478_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BSE5

KEGG Orthology (KO)

More...KOi		K01480

Identification of Orthologs from Complete Genome Data

More...OMAi		DTYFGAE

Database of Orthologous Groups

More...OrthoDBi		921352at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BSE5

TreeFam database of animal gene trees

More...TreeFami		TF328612

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005925, Agmatinase-rel
IPR006035, Ureohydrolase
IPR023696, Ureohydrolase_dom_sf
IPR020855, Ureohydrolase_Mn_BS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00491, Arginase, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF036979, Arginase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00116, ARGINASE

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52768, SSF52768, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01230, agmatinase, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01053, ARGINASE_1, 1 hit
PS51409, ARGINASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BSE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRLLASGCA RGPGPGVGAR PAAGLFHPGR RQSRQASDAP RNQPPSPEFV 
        60         70         80         90        100
ARPVGVCSMM RLPVQTSPEG LDAAFIGVPL DTGTSNRPGA RFGPRRIREE 
       110        120        130        140        150
SVMLGTVNPS TGALPFQSLM VADLGDVNVN LYNLQDSCRR IQEAYEKIVA 
       160        170        180        190        200
AGCIPLTLGG DHTITYPILQ AMAKKHGPVG LLHVDAHTDT TDKALGEKLY 
       210        220        230        240        250
HGAPFRRCVD EGLLDCKRVV QIGIRGSSTT LDPYRYNRSQ GFRVVLAEDC 
       260        270        280        290        300
WMKSLVPLMG EVRQQMGGKP IYISFDIDAL DPAYAPGTGT PEIAGLTPSQ 
       310        320        330        340        350
ALEIIRGCQG LNVMGCDLVE VSPPYDLSGN TALLAANLLF EMLCALPKVT 

TV
Length:352
Mass (Da):37,660
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i394738202353314A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti145Y → C in BAB15633 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_023485105G → R3 PublicationsCorresponds to variant dbSNP:rs6429757Ensembl.1
Natural variantiVAR_048332140R → Q1 PublicationCorresponds to variant dbSNP:rs11580170Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY057097 mRNA Translation: AAL24446.1
AK027037 mRNA Translation: BAB15633.1
AL121992 Genomic DNA No translation available.
BC005090 mRNA Translation: AAH05090.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS160.1

NCBI Reference Sequences

More...RefSeqi		NP_079034.3, NM_024758.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000375826; ENSP00000364986; ENSG00000116771

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79814

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79814

UCSC genome browser

More...UCSCi		uc001awv.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY057097 mRNA Translation: AAL24446.1
AK027037 mRNA Translation: BAB15633.1
AL121992 Genomic DNA No translation available.
BC005090 mRNA Translation: AAH05090.1
CCDSiCCDS160.1
RefSeqiNP_079034.3, NM_024758.4

3D structure databases

SMRiQ9BSE5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122909, 28 interactors
IntActiQ9BSE5, 3 interactors
STRINGi9606.ENSP00000364986

PTM databases

iPTMnetiQ9BSE5
PhosphoSitePlusiQ9BSE5

Polymorphism and mutation databases

BioMutaiAGMAT
DMDMi126302602

Proteomic databases

EPDiQ9BSE5
jPOSTiQ9BSE5
MassIVEiQ9BSE5
MaxQBiQ9BSE5
PaxDbiQ9BSE5
PeptideAtlasiQ9BSE5
PRIDEiQ9BSE5
ProteomicsDBi78882

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		14379, 89 antibodies

The DNASU plasmid repository

More...DNASUi		79814

Genome annotation databases

EnsembliENST00000375826; ENSP00000364986; ENSG00000116771
GeneIDi79814
KEGGihsa:79814
UCSCiuc001awv.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79814
DisGeNETi79814
EuPathDBiHostDB:ENSG00000116771.5

GeneCards: human genes, protein and diseases

More...GeneCardsi		AGMAT
HGNCiHGNC:18407, AGMAT
HPAiENSG00000116771, Tissue enhanced (intestine, kidney, liver)
MIMi617887, gene
neXtProtiNX_Q9BSE5
OpenTargetsiENSG00000116771
PharmGKBiPA24619

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2964, Eukaryota
GeneTreeiENSGT00950000183195
HOGENOMiCLU_039478_0_0_1
InParanoidiQ9BSE5
KOiK01480
OMAiDTYFGAE
OrthoDBi921352at2759
PhylomeDBiQ9BSE5
TreeFamiTF328612

Enzyme and pathway databases

UniPathwayiUPA00534;UER00287
BioCyciMetaCyc:HS04051-MONOMER
BRENDAi3.5.3.11, 2681
PathwayCommonsiQ9BSE5
ReactomeiR-HSA-351143, Agmatine biosynthesis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79814, 9 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		AGMAT, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		Agmatinase

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79814
PharosiQ9BSE5, Tbio

Protein Ontology

More...PROi		PR:Q9BSE5
RNActiQ9BSE5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000116771, Expressed in cortex of kidney and 163 other tissues
ExpressionAtlasiQ9BSE5, baseline and differential
GenevisibleiQ9BSE5, HS

Family and domain databases

InterProiView protein in InterPro
IPR005925, Agmatinase-rel
IPR006035, Ureohydrolase
IPR023696, Ureohydrolase_dom_sf
IPR020855, Ureohydrolase_Mn_BS
PfamiView protein in Pfam
PF00491, Arginase, 1 hit
PIRSFiPIRSF036979, Arginase, 1 hit
PRINTSiPR00116, ARGINASE
SUPFAMiSSF52768, SSF52768, 1 hit
TIGRFAMsiTIGR01230, agmatinase, 1 hit
PROSITEiView protein in PROSITE
PS01053, ARGINASE_1, 1 hit
PS51409, ARGINASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPEB_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BSE5
Secondary accession number(s): Q5TDH1, Q9H5J3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: February 20, 2007
Last modified: August 12, 2020
This is version 168 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  5. SIMILARITY comments
    Index of protein domains and families
  6. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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