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UniProtKB - Q9BSC4 (NOL10_HUMAN)

Entry version 159 (07 Apr 2021)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

Nucleolar protein 10

Gene

NOL10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BSC4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOL10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25862, NOL10

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		616197, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BSC4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000115761.15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79954

Open Targets

More...OpenTargetsi		ENSG00000115761

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142671257

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BSC4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		NOL10

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000511011 – 688Nucleolar protein 10Add BLAST688

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei25PhosphoserineCombined sources1
Modified residuei475PhosphoserineCombined sources1
Modified residuei481PhosphothreonineCombined sources1
Modified residuei514PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BSC4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BSC4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BSC4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BSC4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BSC4

PeptideAtlas

More...PeptideAtlasi		Q9BSC4

PRoteomics IDEntifications database

More...PRIDEi		Q9BSC4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		4565
78875 [Q9BSC4-1]
78876 [Q9BSC4-2]
78877 [Q9BSC4-3]

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		Q9BSC4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BSC4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BSC4

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9BSC4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000115761, Expressed in sperm and 216 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BSC4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BSC4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000115761, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123023, 74 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9BSC4

Protein interaction database and analysis system

More...IntActi		Q9BSC4, 28 interactors

Molecular INTeraction database

More...MINTi		Q9BSC4

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000371101

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BSC4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati44 – 82WD 1Add BLAST39
Repeati88 – 124WD 2Add BLAST37
Repeati127 – 163WD 3Add BLAST37
Repeati170 – 205WD 4Add BLAST36
Repeati219 – 258WD 5Add BLAST40
Repeati262 – 300WD 6Add BLAST39
Repeati304 – 341WD 7Add BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili423 – 446Sequence analysisAdd BLAST24
Coiled coili514 – 589Sequence analysisAdd BLAST76
Coiled coili640 – 673Sequence analysisAdd BLAST34

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat NOL10/ENP2 family.Curated

Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2321, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007900

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_009923_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BSC4

Identification of Orthologs from Complete Genome Data

More...OMAi		GEWVMST

Database of Orthologous Groups

More...OrthoDBi		1099332at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BSC4

TreeFam database of animal gene trees

More...TreeFami		TF105808

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR040382, NOL10/Enp2
IPR012580, NUC153
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR14927, PTHR14927, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08159, NUC153, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00320, WD40, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BSC4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQVSSLNEVK IYSLSCGKSL PEWLSDRKKR ALQKKDVDVR RRIELIQDFE 
        60         70         80         90        100
MPTVCTTIKV SKDGQYILAT GTYKPRVRCY DTYQLSLKFE RCLDSEVVTF 
       110        120        130        140        150
EILSDDYSKI VFLHNDRYIE FHSQSGFYYK TRIPKFGRDF SYHYPSCDLY 
       160        170        180        190        200
FVGASSEVYR LNLEQGRYLN PLQTDAAENN VCDINSVHGL FATGTIEGRV 
       210        220        230        240        250
ECWDPRTRNR VGLLDCALNS VTADSEINSL PTISALKFNG ALTMAVGTTT 
       260        270        280        290        300
GQVLLYDLRS DKPLLVKDHQ YGLPIKSVHF QDSLDLILSA DSRIVKMWNK 
       310        320        330        340        350
NSGKIFTSLE PEHDLNDVCL YPNSGMLLTA NETPKMGIYY IPVLGPAPRW 
       360        370        380        390        400
CSFLDNLTEE LEENPESTVY DDYKFVTKKD LENLGLTHLI GSPFLRAYMH 
       410        420        430        440        450
GFFMDIRLYH KVKLMVNPFA YEEYRKDKIR QKIEETRAQR VQLKKLPKVN 
       460        470        480        490        500
KELALKLIEE EEEKQKSTWK KKVKSLPNIL TDDRFKVMFE NPDFQVDEES 
       510        520        530        540        550
EEFRLLNPLV SKISEKRKKK LRLLEQQELR EKEEEEEPEG KPSDAESSES 
       560        570        580        590        600
SDDEKAWVEE VRKQRRLLQQ EEKVKRQERL KEDQQTVLKP QFYEIKAGEE 
       610        620        630        640        650
FRSFKDSATK QKLMNKTLED RLKIEAKNGT LSVSDTTVGS KQLTFTLKRS 
       660        670        680 
EQQKKQQEAE KLHRQERKRL RRSAGHLKSR HKRGRSFH
Length:688
Mass (Da):80,302
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i27C3C9E0D7A4FA33
GO
Isoform 2 (identifier: Q9BSC4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     253-302: Missing.

Show »
Length:638
Mass (Da):74,509
Checksum:i13A71D5045CD8B2F
GO
Isoform 3 (identifier: Q9BSC4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-150: Missing.
     151-154: FVGA → MTTQ
     343-345: VLG → PSL
     346-688: Missing.

Show »
Length:195
Mass (Da):21,578
Checksum:i106DF2BDCA17093A
GO
Isoform 4 (identifier: Q9BSC4-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     71-96: Missing.

Show »
Length:662
Mass (Da):77,148
Checksum:i63AD4D21BC5C50ED
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C1Z3H7C1Z3_HUMAN
Nucleolar protein 10
NOL10
252Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti494F → L in BAB14836 (PubMed:14702039).Curated1
Sequence conflicti570Q → R in BAB14836 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060041635D → N. Corresponds to variant dbSNP:rs2287059Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0154541 – 150Missing in isoform 3. 1 PublicationAdd BLAST150
Alternative sequenceiVSP_04512271 – 96Missing in isoform 4. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_015455151 – 154FVGA → MTTQ in isoform 3. 1 Publication4
Alternative sequenceiVSP_015456253 – 302Missing in isoform 2. 1 PublicationAdd BLAST50
Alternative sequenceiVSP_015457343 – 345VLG → PSL in isoform 3. 1 Publication3
Alternative sequenceiVSP_015458346 – 688Missing in isoform 3. 1 PublicationAdd BLAST343

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK024000 mRNA Translation: BAB14765.1
AK024137 mRNA Translation: BAB14836.1
AK290680 mRNA Translation: BAF83369.1
AK297169 mRNA Translation: BAG59662.1
AC007314 Genomic DNA Translation: AAK52071.2
AC092687 Genomic DNA Translation: AAY24068.1
CH471053 Genomic DNA Translation: EAX00955.1
BC005125 mRNA Translation: AAH05125.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1673.2 [Q9BSC4-1]
CCDS58697.1 [Q9BSC4-4]
CCDS58698.1 [Q9BSC4-2]

NCBI Reference Sequences

More...RefSeqi		NP_001248321.1, NM_001261392.1 [Q9BSC4-4]
NP_001248323.1, NM_001261394.1 [Q9BSC4-2]
NP_079170.2, NM_024894.3 [Q9BSC4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000345985; ENSP00000263837; ENSG00000115761 [Q9BSC4-2]
ENST00000381685; ENSP00000371101; ENSG00000115761 [Q9BSC4-1]
ENST00000538384; ENSP00000439663; ENSG00000115761 [Q9BSC4-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79954

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79954

UCSC genome browser

More...UCSCi		uc002rap.4, human [Q9BSC4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK024000 mRNA Translation: BAB14765.1
AK024137 mRNA Translation: BAB14836.1
AK290680 mRNA Translation: BAF83369.1
AK297169 mRNA Translation: BAG59662.1
AC007314 Genomic DNA Translation: AAK52071.2
AC092687 Genomic DNA Translation: AAY24068.1
CH471053 Genomic DNA Translation: EAX00955.1
BC005125 mRNA Translation: AAH05125.1
CCDSiCCDS1673.2 [Q9BSC4-1]
CCDS58697.1 [Q9BSC4-4]
CCDS58698.1 [Q9BSC4-2]
RefSeqiNP_001248321.1, NM_001261392.1 [Q9BSC4-4]
NP_001248323.1, NM_001261394.1 [Q9BSC4-2]
NP_079170.2, NM_024894.3 [Q9BSC4-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi123023, 74 interactors
CORUMiQ9BSC4
IntActiQ9BSC4, 28 interactors
MINTiQ9BSC4
STRINGi9606.ENSP00000371101

PTM databases

iPTMnetiQ9BSC4
PhosphoSitePlusiQ9BSC4
SwissPalmiQ9BSC4

Genetic variation databases

BioMutaiNOL10

2D gel databases

SWISS-2DPAGEiQ9BSC4

Proteomic databases

EPDiQ9BSC4
jPOSTiQ9BSC4
MassIVEiQ9BSC4
MaxQBiQ9BSC4
PaxDbiQ9BSC4
PeptideAtlasiQ9BSC4
PRIDEiQ9BSC4
ProteomicsDBi4565
78875 [Q9BSC4-1]
78876 [Q9BSC4-2]
78877 [Q9BSC4-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26703, 95 antibodies

Genome annotation databases

EnsembliENST00000345985; ENSP00000263837; ENSG00000115761 [Q9BSC4-2]
ENST00000381685; ENSP00000371101; ENSG00000115761 [Q9BSC4-1]
ENST00000538384; ENSP00000439663; ENSG00000115761 [Q9BSC4-4]
GeneIDi79954
KEGGihsa:79954
UCSCiuc002rap.4, human [Q9BSC4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79954
DisGeNETi79954

GeneCards: human genes, protein and diseases

More...GeneCardsi		NOL10
HGNCiHGNC:25862, NOL10
HPAiENSG00000115761, Low tissue specificity
MIMi616197, gene
neXtProtiNX_Q9BSC4
OpenTargetsiENSG00000115761
PharmGKBiPA142671257
VEuPathDBiHostDB:ENSG00000115761.15

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2321, Eukaryota
GeneTreeiENSGT00390000007900
HOGENOMiCLU_009923_2_0_1
InParanoidiQ9BSC4
OMAiGEWVMST
OrthoDBi1099332at2759
PhylomeDBiQ9BSC4
TreeFamiTF105808

Enzyme and pathway databases

PathwayCommonsiQ9BSC4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79954, 750 hits in 971 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		NOL10, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79954
PharosiQ9BSC4, Tdark

Protein Ontology

More...PROi		PR:Q9BSC4
RNActiQ9BSC4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000115761, Expressed in sperm and 216 other tissues
ExpressionAtlasiQ9BSC4, baseline and differential
GenevisibleiQ9BSC4, HS

Family and domain databases

InterProiView protein in InterPro
IPR040382, NOL10/Enp2
IPR012580, NUC153
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf
PANTHERiPTHR14927, PTHR14927, 1 hit
PfamiView protein in Pfam
PF08159, NUC153, 1 hit
SMARTiView protein in SMART
SM00320, WD40, 5 hits
SUPFAMiSSF50978, SSF50978, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOL10_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BSC4
Secondary accession number(s): A8K3R5
, B4DLV0, Q53RC9, Q96TA5, Q9H7Y7, Q9H855
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2001
Last modified: April 7, 2021
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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