UniProtKB - Q9BSA0 (Q9BSA0_HUMAN)

BLAST

>tr|Q9BSA0|Q9BSA0_HUMAN TMEM51 protein OS=Homo sapiens OX=9606 GN=TMEM51 PE=1 SV=1
MMAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTEVGGGILKS
KTFSVAYVLVGAGVMLLLLSICLSIRDKRKQRQGEDLAHVQHPTGAGPHAQEEDRRKKRR
MRRLPQGTMFPATRK

Align
Format
Add to basket Added to basket
History
Entry version 85 (07 Nov 2018)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

Submitted name:

TMEM51 protein

Gene

TMEM51

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: TMEM51 proteinImported Submitted name: Transmembrane protein 51Imported Submitted name: Transmembrane protein 51, isoform CRA_cImported
Gene namesⁱ	Name:TMEM51Imported ORF Names:hCG_25381Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000171729.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:25488 TMEM51

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	12 – 34	HelicalSequence analysisAdd BLAST		23
Transmembraneⁱ	65 – 85	HelicalSequence analysisAdd BLAST		21

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000171729

OpenTargetsⁱ

ENSG00000171729

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000171729 Expressed in 153 organ(s), highest expression level in islet of Langerhans

Bgeeⁱ

ENSG00000171729 Expressed in 153 organ(s), highest expression level in islet of Langerhans

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
PTPN5	P54829	3	EBI-10297449,EBI-1220572

With

Entry

#Exp.

IntAct

Notes

PTPN5

P54829

EBI-10297449,EBI-1220572

Protein-protein interaction databases

IntActⁱ	Q9BSA0, 1 interactor Q9BSA0, 1 interactor

IntActⁱ

Q9BSA0, 1 interactor
Q9BSA0, 1 interactor

Family & Domainsⁱ

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IJTH Eukaryota ENOG4111TGG LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000009278

Family and domain databases

InterProⁱ	View protein in InterPro IPR029265 TMEM51
PANTHERⁱ	PTHR16015 PTHR16015, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

Q9BSA0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMAQSKANGS HYALTAIGLG MLVLGVIMAM WNLVPGFSAA EKPTAQGSNK 
        60         70         80         90        100
TEVGGGILKS KTFSVAYVLV GAGVMLLLLS ICLSIRDKRK QRQGEDLAHV 
       110        120        130 
QHPTGAGPHA QEEDRRKKRR MRRLPQGTMF PATRK

Length:135

Mass (Da):14,627

Last modified:June 1, 2001 - v1

Checksum:ⁱFC772797912D21FD

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q9NW97	TMM51_HUMAN	Transmembrane protein 51 Transmembrane protein 51	TMEM51 C1orf72	253	Annotation score:
B1AP03	B1AP03_HUMAN	Transmembrane protein 51 Transmembrane protein 51	TMEM51	121	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL035405 Genomic DNA No translation available. AL391094 Genomic DNA No translation available. BC005177 mRNA Translation: AAH05177.1 CH471167 Genomic DNA Translation: EAW51712.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001306594.1, NM_001319665.1
UniGeneⁱ	Hs.465305

Genome annotation databases

Ensemblⁱ	ENST00000434578; ENSP00000409665; ENSG00000171729
GeneIDⁱ	55092
UCSC genome browser More...UCSCⁱ	uc001avz.4 human

Protein	Similar proteins		Species	Score	Length	Source
Q9BSA0	TMEM51 isoform 4		PANTR		135	UniRef100_Q9BSA0

Protein	Similar proteins		Species	Score	Length	Source
Q9BSA0	TMEM51 isoform 4		PANTR		135	UniRef90_Q9BSA0
TMEM51 isoform 5 (Fragment)		PONAB		135
UPI00080A2E80		Cebus capucinus imitator		133
UPI00083EA1F9		PAPAN		133
UPI0008405D01		CALJA		133
+3

Protein	Similar proteins		Species	Score	Length	Source
Q9BSA0	TMEM51 isoform 4		PANTR		135	UniRef50_Q9BSA0
TMEM51 isoform 5 (Fragment)		PONAB		135
Transmembrane protein 51		ALLMI		117
Transmembrane protein 51 (Fragment)		NEOVI		122
Transmembrane protein 51		CRIGR		113
+12

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL035405 Genomic DNA No translation available. AL391094 Genomic DNA No translation available. BC005177 mRNA Translation: AAH05177.1 CH471167 Genomic DNA Translation: EAW51712.1
RefSeqⁱ	NP_001306594.1, NM_001319665.1
UniGeneⁱ	Hs.465305

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q9BSA0, 1 interactor Q9BSA0, 1 interactor

IntActⁱ

Q9BSA0, 1 interactor
Q9BSA0, 1 interactor

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000434578; ENSP00000409665; ENSG00000171729
GeneIDⁱ	55092
UCSCⁱ	uc001avz.4 human

Organism-specific databases

CTDⁱ	55092
EuPathDBⁱ	HostDB:ENSG00000171729.13
HGNCⁱ	HGNC:25488 TMEM51
OpenTargetsⁱ	ENSG00000171729
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IJTH Eukaryota ENOG4111TGG LUCA
GeneTreeⁱ	ENSGT00390000009278

Miscellaneous databases

ChiTaRSⁱ	TMEM51 human

ChiTaRSⁱ

TMEM51 human

Gene expression databases

Bgeeⁱ	ENSG00000171729 Expressed in 153 organ(s), highest expression level in islet of Langerhans

Bgeeⁱ

ENSG00000171729 Expressed in 153 organ(s), highest expression level in islet of Langerhans

Family and domain databases

InterProⁱ	View protein in InterPro IPR029265 TMEM51
PANTHERⁱ	PTHR16015 PTHR16015, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9BSA0_HUMAN
Accessionⁱ	Q9BSA0Primary (citable) accession number: Q9BSA0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 2001
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9BSA0 (Q9BSA0_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

TMEM51 protein

TMEM51

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ