UniProtKB - Q9BSA0 (Q9BSA0_HUMAN)
Protein
Submitted name:
TMEM51 protein
Gene
TMEM51
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: TMEM51 proteinImportedSubmitted name: Transmembrane protein 51ImportedSubmitted name: Transmembrane protein 51, isoform CRA_cImported |
Gene namesi | Name:TMEM51Imported ORF Names:hCG_25381Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25488, TMEM51 |
VEuPathDBi | HostDB:ENSG00000171729.13 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 34 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 65 – 85 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000171729, Expressed in body of pancreas and 167 other tissues |
ExpressionAtlasi | Q9BSA0, baseline and differential |
Interactioni
Binary interactionsi
Q9BSA0
With | #Exp. | IntAct |
---|---|---|
PTPN5 [P54829] | 3 | EBI-10297449,EBI-1220572 |
Protein-protein interaction databases
IntActi | Q9BSA0, 1 interactor |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 92 – 135 | DisorderedSequence analysisAdd BLAST | 44 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00390000009278 |
HOGENOMi | CLU_2043352_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR029265, TMEM51 |
PANTHERi | PTHR16015, PTHR16015, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q9BSA0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMAQSKANGS HYALTAIGLG MLVLGVIMAM WNLVPGFSAA EKPTAQGSNK
60 70 80 90 100
TEVGGGILKS KTFSVAYVLV GAGVMLLLLS ICLSIRDKRK QRQGEDLAHV
110 120 130
QHPTGAGPHA QEEDRRKKRR MRRLPQGTMF PATRK
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NW97 | TMM51_HUMAN | Transmembrane protein 51 | TMEM51 C1orf72 | 253 | Annotation score: | ||
B1AP03 | B1AP03_HUMAN | Transmembrane protein 51 | TMEM51 | 121 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035405 Genomic DNA No translation available. AL391094 Genomic DNA No translation available. BC005177 mRNA Translation: AAH05177.1 CH471167 Genomic DNA Translation: EAW51712.1 |
RefSeqi | NP_001306594.1, NM_001319665.1 |
Genome annotation databases
Ensembli | ENST00000434578; ENSP00000409665; ENSG00000171729 |
GeneIDi | 55092 |
UCSCi | uc001avz.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035405 Genomic DNA No translation available. AL391094 Genomic DNA No translation available. BC005177 mRNA Translation: AAH05177.1 CH471167 Genomic DNA Translation: EAW51712.1 |
RefSeqi | NP_001306594.1, NM_001319665.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9BSA0, 1 interactor |
Proteomic databases
PRIDEi | Q9BSA0 |
Protocols and materials databases
Antibodypediai | 3057, 40 antibodies |
Genome annotation databases
Ensembli | ENST00000434578; ENSP00000409665; ENSG00000171729 |
GeneIDi | 55092 |
UCSCi | uc001avz.4, human |
Organism-specific databases
CTDi | 55092 |
HGNCi | HGNC:25488, TMEM51 |
OpenTargetsi | ENSG00000171729 |
VEuPathDBi | HostDB:ENSG00000171729.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000009278 |
HOGENOMi | CLU_2043352_0_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 55092, 3 hits in 876 CRISPR screens |
ChiTaRSi | TMEM51, human |
GenomeRNAii | 55092 |
Gene expression databases
Bgeei | ENSG00000171729, Expressed in body of pancreas and 167 other tissues |
ExpressionAtlasi | Q9BSA0, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR029265, TMEM51 |
PANTHERi | PTHR16015, PTHR16015, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9BSA0_HUMAN | |
Accessioni | Q9BSA0Primary (citable) accession number: Q9BSA0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |