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UniProtKB - Q9BS86 (ZPBP1_HUMAN)

Entry version 139 (10 Feb 2021)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

Zona pellucida-binding protein 1

Gene

ZPBP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in acrosome compaction and sperm morphogenesis (PubMed:21911476). Is implicated in sperm-oocyte interaction during fertilization (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BS86

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zona pellucida-binding protein 1
Alternative name(s):
Inner acrosomal membrane IAM38By similarity
Sp38
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZPBP
Synonyms:ZPBP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:15662, ZPBP

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		608498, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BS86

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000042813.7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		11055

Open Targets

More...OpenTargetsi		ENSG00000042813

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38013

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BS86, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZPBP

Domain mapping of disease mutations (DMDM)

More...DMDMi		54036652

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 44Sequence analysisAdd BLAST44
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004159845 – 351Zona pellucida-binding protein 1Add BLAST307

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi114N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi187N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi340N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BS86

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BS86

PeptideAtlas

More...PeptideAtlasi		Q9BS86

PRoteomics IDEntifications database

More...PRIDEi		Q9BS86

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		11161
78866 [Q9BS86-1]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9BS86, 3 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BS86

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BS86

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed specifically in testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000042813, Expressed in testis and 96 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BS86, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BS86, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000042813, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		116240, 4 interactors

Protein interaction database and analysis system

More...IntActi		Q9BS86, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000046087

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BS86, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the zona pellucida-binding protein Sp38 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RJ20, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00520000055647

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_056016_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BS86

Identification of Orthologs from Complete Genome Data

More...OMAi		GIHCLPC

Database of Orthologous Groups

More...OrthoDBi		1069241at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BS86

TreeFam database of animal gene trees

More...TreeFami		TF335677

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR010857, Sp38-bd

The PANTHER Classification System

More...PANTHERi		PTHR15443, PTHR15443, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07354, Sp38, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BS86-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEAFALGPAR RGRRRTRAAG SLLSRAAILL FISAFLVRVP SSVGHLVRLP 
        60         70         80         90        100
RAFRLTKDSV KIVGSTSFPV KAYVMLHQKS PHVLCVTQQL RNAELIDPSF 
       110        120        130        140        150
QWYGPKGKVV SVENRTAQIT STGSLVFQNF EESMSGIYTC FLEYKPTVEE 
       160        170        180        190        200
IVKRLQLKYA IYAYREPHYY YQFTARYHAA PCNSIYNISF EKKLLQILSK 
       210        220        230        240        250
LLLDLSCEIS LLKSECHRVK MQRAGLQNEL FFAFSVSSLD TEKGPKRCTD 
       260        270        280        290        300
HNCEPYKRLF KAKNLIERFF NQQVEILGRR AEQLPQIYYI EGTLQMVWIN 
       310        320        330        340        350
RCFPGYGMNV QQHPKCPECC VICSPGSYNP RDGIHCLQCN SSLVYGAKTC 

L
Length:351
Mass (Da):40,142
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B57027FBE12E7DB
GO
Isoform 2 (identifier: Q9BS86-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     112-112: Missing.

Show »
Length:350
Mass (Da):40,043
Checksum:i13D2B6ADB4408925
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JIS7C9JIS7_HUMAN
Zona pellucida-binding protein 1
ZPBP
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WDW2F8WDW2_HUMAN
Zona pellucida-binding protein 1
ZPBP
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAS07517 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti180A → V in BAA04495 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07682617R → P1 PublicationCorresponds to variant dbSNP:rs202231065EnsemblClinVar.1
Natural variantiVAR_07682725R → P1 PublicationCorresponds to variant dbSNP:rs61696422Ensembl.1
Natural variantiVAR_076828184S → G Found in an infertile patient with teratozoospermia; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1299521157Ensembl.1
Natural variantiVAR_076829217H → L Found in an infertile patient with teratozoospermia; unknown pathological significance. 1 Publication1
Natural variantiVAR_076830225G → S Found in an infertile patient with teratozoospermia; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1468321681Ensembl.1
Natural variantiVAR_076831252N → S Found in an infertile patient with teratozoospermia; unknown pathological significance. 1 Publication1
Natural variantiVAR_076832287I → T Found in an infertile patient with teratozoospermia; unknown pathological significance. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_045491112Missing in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D17570 mRNA Translation: BAA04495.1
BT006822 mRNA Translation: AAP35468.1
AK312799 mRNA No translation available.
AC020743 Genomic DNA No translation available.
AC034145 Genomic DNA No translation available.
AC096568 Genomic DNA Translation: AAS07517.1 Different initiation.
AC034148 Genomic DNA Translation: AAS07558.1
CH236955 Genomic DNA Translation: EAL23903.1
CH471128 Genomic DNA Translation: EAW60984.1
BC005223 mRNA Translation: AAH05223.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS5509.1 [Q9BS86-1]
CCDS55110.1 [Q9BS86-2]

NCBI Reference Sequences

More...RefSeqi		NP_001153350.1, NM_001159878.1 [Q9BS86-2]
NP_008940.2, NM_007009.2 [Q9BS86-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000046087; ENSP00000046087; ENSG00000042813 [Q9BS86-1]
ENST00000419417; ENSP00000402071; ENSG00000042813 [Q9BS86-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		11055

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:11055

UCSC genome browser

More...UCSCi		uc003tou.4, human [Q9BS86-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17570 mRNA Translation: BAA04495.1
BT006822 mRNA Translation: AAP35468.1
AK312799 mRNA No translation available.
AC020743 Genomic DNA No translation available.
AC034145 Genomic DNA No translation available.
AC096568 Genomic DNA Translation: AAS07517.1 Different initiation.
AC034148 Genomic DNA Translation: AAS07558.1
CH236955 Genomic DNA Translation: EAL23903.1
CH471128 Genomic DNA Translation: EAW60984.1
BC005223 mRNA Translation: AAH05223.1
CCDSiCCDS5509.1 [Q9BS86-1]
CCDS55110.1 [Q9BS86-2]
RefSeqiNP_001153350.1, NM_001159878.1 [Q9BS86-2]
NP_008940.2, NM_007009.2 [Q9BS86-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi116240, 4 interactors
IntActiQ9BS86, 2 interactors
STRINGi9606.ENSP00000046087

PTM databases

GlyGeniQ9BS86, 3 sites
iPTMnetiQ9BS86
PhosphoSitePlusiQ9BS86

Genetic variation databases

BioMutaiZPBP
DMDMi54036652

Proteomic databases

MassIVEiQ9BS86
PaxDbiQ9BS86
PeptideAtlasiQ9BS86
PRIDEiQ9BS86
ProteomicsDBi11161
78866 [Q9BS86-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		55139, 68 antibodies

The DNASU plasmid repository

More...DNASUi		11055

Genome annotation databases

EnsembliENST00000046087; ENSP00000046087; ENSG00000042813 [Q9BS86-1]
ENST00000419417; ENSP00000402071; ENSG00000042813 [Q9BS86-2]
GeneIDi11055
KEGGihsa:11055
UCSCiuc003tou.4, human [Q9BS86-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11055
DisGeNETi11055

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZPBP
HGNCiHGNC:15662, ZPBP
HPAiENSG00000042813, Tissue enriched (testis)
MIMi608498, gene
neXtProtiNX_Q9BS86
OpenTargetsiENSG00000042813
PharmGKBiPA38013
VEuPathDBiHostDB:ENSG00000042813.7

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RJ20, Eukaryota
GeneTreeiENSGT00520000055647
HOGENOMiCLU_056016_0_1_1
InParanoidiQ9BS86
OMAiGIHCLPC
OrthoDBi1069241at2759
PhylomeDBiQ9BS86
TreeFamiTF335677

Enzyme and pathway databases

PathwayCommonsiQ9BS86

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		11055, 8 hits in 872 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZPBP, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		11055
PharosiQ9BS86, Tdark

Protein Ontology

More...PROi		PR:Q9BS86
RNActiQ9BS86, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000042813, Expressed in testis and 96 other tissues
ExpressionAtlasiQ9BS86, baseline and differential
GenevisibleiQ9BS86, HS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR010857, Sp38-bd
PANTHERiPTHR15443, PTHR15443, 1 hit
PfamiView protein in Pfam
PF07354, Sp38, 1 hit
SUPFAMiSSF48726, SSF48726, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZPBP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BS86
Secondary accession number(s): A4D253
, C9JPU1, Q15941, Q75KX9, Q75MI3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: June 1, 2001
Last modified: February 10, 2021
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with genetic variants
    List of human entries with genetic variants
  2. Human variants curated from literature reports
    Index of human variants curated from literature reports
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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