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UniProtKB - Q9BRX2 (PELO_HUMAN)

Entry version 150 (13 Feb 2019)
Sequence version 2 (08 Feb 2011)
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Protein

Protein pelota homolog

Gene

PELO

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential).By similarityCurated

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

a divalent metal cationCurated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • endonuclease activity Source: UniProtKB-KW
  • metal ion binding Source: UniProtKB-KW
  • ribosome binding Source: GO_Central
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processCell cycle, Cell division
LigandMetal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein pelota homolog (EC:3.1.-.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PELO
ORF Names:CGI-17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000152684.10

Human Gene Nomenclature Database

More...HGNCi		HGNC:8829 PELO

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		605757 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BRX2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		53918

Open Targets

More...OpenTargetsi		ENSG00000152684

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA33174

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PELO

Domain mapping of disease mutations (DMDM)

More...DMDMi		322510057

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001431881 – 385Protein pelota homologAdd BLAST385

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki162Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei374PhosphoserineCombined sources1
Modified residuei380PhosphoserineCombined sources1
Modified residuei381PhosphoserineCombined sources1
Modified residuei382PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BRX2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BRX2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BRX2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BRX2

PeptideAtlas

More...PeptideAtlasi		Q9BRX2

PRoteomics IDEntifications database

More...PRIDEi		Q9BRX2

ProteomicsDB human proteome resource

More...ProteomicsDBi		78846

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BRX2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BRX2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000152684 Expressed in 220 organ(s), highest expression level in islet of Langerhans

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BRX2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA031458

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		119818, 82 interactors

Protein interaction database and analysis system

More...IntActi		Q9BRX2, 27 interactors

Molecular INTeraction database

More...MINTi		Q9BRX2

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000274311

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1385
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X52NMR-A261-371[»]
5EO3X-ray2.60A/B265-385[»]
5LZWelectron microscopy3.53ii1-385[»]
5LZXelectron microscopy3.67ii1-385[»]
5LZYelectron microscopy3.99ii1-385[»]
5LZZelectron microscopy3.47ii1-385[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q9BRX2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BRX2

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q9BRX2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity (Potential).Curated

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic release factor 1 family. Pelota subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2869 Eukaryota
COG1537 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016326

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000184162

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG053560

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BRX2

KEGG Orthology (KO)

More...KOi		K06965

Identification of Orthologs from Complete Genome Data

More...OMAi		DNLFRCQ

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BRX2

TreeFam database of animal gene trees

More...TreeFami		TF105733

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.30.870, 1 hit
3.30.1330.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005140 eRF1_1_Pelota
IPR005141 eRF1_2
IPR005142 eRF1_3
IPR029064 L30e-like
IPR038069 Pelota/DOM34_N
IPR004405 Transl-rel_pelota

The PANTHER Classification System

More...PANTHERi		PTHR10853 PTHR10853, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03463 eRF1_1, 1 hit
PF03464 eRF1_2, 1 hit
PF03465 eRF1_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01194 eRF1_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF159065 SSF159065, 1 hit
SSF55315 SSF55315, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00111 pelota, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9BRX2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLVRKNIEK DNAGQVTLVP EEPEDMWHTY NLVQVGDSLR ASTIRKVQTE 
        60         70         80         90        100
SSTGSVGSNR VRTTLTLCVE AIDFDSQACQ LRVKGTNIQE NEYVKMGAYH 
       110        120        130        140        150
TIELEPNRQF TLAKKQWDSV VLERIEQACD PAWSADVAAV VMQEGLAHIC 
       160        170        180        190        200
LVTPSMTLTR AKVEVNIPRK RKGNCSQHDR ALERFYEQVV QAIQRHIHFD 
       210        220        230        240        250
VVKCILVASP GFVREQFCDY LFQQAVKTDN KLLLENRSKF LQVHASSGHK 
       260        270        280        290        300
YSLKEALCDP TVASRLSDTK AAGEVKALDD FYKMLQHEPD RAFYGLKQVE 
       310        320        330        340        350
KANEAMAIDT LLISDELFRH QDVATRSRYV RLVDSVKENA GTVRIFSSLH 
       360        370        380 
VSGEQLSQLT GVAAILRFPV PELSDQEGDS SSEED
Length:385
Mass (Da):43,359
Last modified:February 8, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A0D264202995B76
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti135A → D in AAG22574 (PubMed:11060452).Curated1
Sequence conflicti135A → D in AAG22575 (PubMed:11060452).Curated1
Sequence conflicti235E → G in AAD27726 (PubMed:10810093).Curated1
Sequence conflicti263 – 264AS → LA in AAD27726 (PubMed:10810093).Curated2
Sequence conflicti281F → S in AAD27726 (PubMed:10810093).Curated1
Sequence conflicti352S → Y in AAG22574 (PubMed:11060452).Curated1
Sequence conflicti352S → Y in AAG22575 (PubMed:11060452).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_019777221L → M4 PublicationsCorresponds to variant dbSNP:rs1499280Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF139828 mRNA Translation: AAG22574.1
AF143952 Genomic DNA Translation: AAG22575.1
AY117399 mRNA Translation: AAM89414.1
AF132951 mRNA Translation: AAD27726.1
AC026230 Genomic DNA No translation available.
BC005889 mRNA Translation: AAH05889.1
BC007249 mRNA Translation: AAH07249.1
BC007650 mRNA Translation: AAH07650.1
BC022789 mRNA Translation: AAH22789.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS3956.1

NCBI Reference Sequences

More...RefSeqi		NP_057030.3, NM_015946.4

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.644352

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000274311; ENSP00000274311; ENSG00000152684

Database of genes from NCBI RefSeq genomes

More...GeneIDi		53918

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:53918

UCSC genome browser

More...UCSCi		uc003jos.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF139828 mRNA Translation: AAG22574.1
AF143952 Genomic DNA Translation: AAG22575.1
AY117399 mRNA Translation: AAM89414.1
AF132951 mRNA Translation: AAD27726.1
AC026230 Genomic DNA No translation available.
BC005889 mRNA Translation: AAH05889.1
BC007249 mRNA Translation: AAH07249.1
BC007650 mRNA Translation: AAH07650.1
BC022789 mRNA Translation: AAH22789.1
CCDSiCCDS3956.1
RefSeqiNP_057030.3, NM_015946.4
UniGeneiHs.644352

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X52NMR-A261-371[»]
5EO3X-ray2.60A/B265-385[»]
5LZWelectron microscopy3.53ii1-385[»]
5LZXelectron microscopy3.67ii1-385[»]
5LZYelectron microscopy3.99ii1-385[»]
5LZZelectron microscopy3.47ii1-385[»]
ProteinModelPortaliQ9BRX2
SMRiQ9BRX2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119818, 82 interactors
IntActiQ9BRX2, 27 interactors
MINTiQ9BRX2
STRINGi9606.ENSP00000274311

PTM databases

iPTMnetiQ9BRX2
PhosphoSitePlusiQ9BRX2

Polymorphism and mutation databases

BioMutaiPELO
DMDMi322510057

Proteomic databases

EPDiQ9BRX2
jPOSTiQ9BRX2
MaxQBiQ9BRX2
PaxDbiQ9BRX2
PeptideAtlasiQ9BRX2
PRIDEiQ9BRX2
ProteomicsDBi78846

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		53918
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000274311; ENSP00000274311; ENSG00000152684
GeneIDi53918
KEGGihsa:53918
UCSCiuc003jos.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		53918
DisGeNETi53918
EuPathDBiHostDB:ENSG00000152684.10

GeneCards: human genes, protein and diseases

More...GeneCardsi		PELO

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0004852
HGNCiHGNC:8829 PELO
HPAiHPA031458
MIMi605757 gene
neXtProtiNX_Q9BRX2
OpenTargetsiENSG00000152684
PharmGKBiPA33174

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2869 Eukaryota
COG1537 LUCA
GeneTreeiENSGT00390000016326
HOGENOMiHOG000184162
HOVERGENiHBG053560
InParanoidiQ9BRX2
KOiK06965
OMAiDNLFRCQ
PhylomeDBiQ9BRX2
TreeFamiTF105733

Miscellaneous databases

EvolutionaryTraceiQ9BRX2

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		PELO

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		53918

Protein Ontology

More...PROi		PR:Q9BRX2

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000152684 Expressed in 220 organ(s), highest expression level in islet of Langerhans
GenevisibleiQ9BRX2 HS

Family and domain databases

Gene3Di2.30.30.870, 1 hit
3.30.1330.30, 1 hit
InterProiView protein in InterPro
IPR005140 eRF1_1_Pelota
IPR005141 eRF1_2
IPR005142 eRF1_3
IPR029064 L30e-like
IPR038069 Pelota/DOM34_N
IPR004405 Transl-rel_pelota
PANTHERiPTHR10853 PTHR10853, 1 hit
PfamiView protein in Pfam
PF03463 eRF1_1, 1 hit
PF03464 eRF1_2, 1 hit
PF03465 eRF1_3, 1 hit
SMARTiView protein in SMART
SM01194 eRF1_1, 1 hit
SUPFAMiSSF159065 SSF159065, 1 hit
SSF55315 SSF55315, 1 hit
TIGRFAMsiTIGR00111 pelota, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPELO_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BRX2
Secondary accession number(s): Q9GZS6, Q9Y306
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: February 8, 2011
Last modified: February 13, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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