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Entry version 136 (22 Apr 2020)
Sequence version 1 (01 Jun 2001)
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Protein

Sugar transporter SWEET1

Gene

SLC50A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-189200 Cellular hexose transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.123.1.4 the sweet, pq-loop, saliva, mtn3 (sweet) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sugar transporter SWEET1
Short name:
HsSWEET1
Alternative name(s):
RAG1-activating protein 1
Solute carrier family 50 member 1
Stromal cell protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC50A1
Synonyms:RAG1AP1, SCP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30657 SLC50A1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
613683 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BRV3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 23Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei42 – 62Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei68 – 88Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei96 – 116Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei129 – 149Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei160 – 180Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei186 – 206Helical; Name=7Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55974

Open Targets

More...
OpenTargetsi
ENSG00000169241

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671099

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BRV3 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC50A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74752289

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003451161 – 221Sugar transporter SWEET1Add BLAST221

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BRV3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BRV3

PeptideAtlas

More...
PeptideAtlasi
Q9BRV3

PRoteomics IDEntifications database

More...
PRIDEi
Q9BRV3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
78840 [Q9BRV3-1]
78841 [Q9BRV3-2]
78842 [Q9BRV3-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BRV3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BRV3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed with highest expression in oviduct, epididymis and intestine.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000169241 Expressed in right lobe of liver and 223 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9BRV3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BRV3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000169241 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TRPV2; the interaction probably occurs intracellularly and depends on TRPV2 N-glycosylation.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
121020, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BRV3, 5 interactors

Molecular INTeraction database

More...
MINTi
Q9BRV3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000357389

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BRV3 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 94MtN3/slv 1Add BLAST85
Domaini127 – 212MtN3/slv 2Add BLAST86

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni149 – 221Mediates interaction with TRPV2By similarityAdd BLAST73

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SWEET sugar transporter family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1623 Eukaryota
ENOG4111M4R LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007801

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_048643_3_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9BRV3

KEGG Orthology (KO)

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KOi
K15382

Identification of Orthologs from Complete Genome Data

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OMAi
IRFYLFW

Database of Orthologous Groups

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OrthoDBi
1116261at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BRV3

TreeFam database of animal gene trees

More...
TreeFami
TF313635

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004316 SWEET_sugar_transpr

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03083 MtN3_slv, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BRV3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEAGGFLDSL IYGACVVFTL GMFSAGLSDL RHMRMTRSVD NVQFLPFLTT
60 70 80 90 100
EVNNLGWLSY GALKGDGILI VVNTVGAALQ TLYILAYLHY CPRKRVVLLQ
110 120 130 140 150
TATLLGVLLL GYGYFWLLVP NPEARLQQLG LFCSVFTISM YLSPLADLAK
160 170 180 190 200
VIQTKSTQCL SYPLTIATLL TSASWCLYGF RLRDPYIMVS NFPGIVTSFI
210 220
RFWLFWKYPQ EQDRNYWLLQ T
Length:221
Mass (Da):25,030
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFEC35396C28EA9F0
GO
Isoform 2 (identifier: Q9BRV3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-55: Missing.
     56-94: GWLSYGALKG...LAYLHYCPRK → MRGLHPWHVL...VPALSHHGSQ

Show »
Length:166
Mass (Da):19,050
Checksum:i04F7A714A75C3BDF
GO
Isoform 3 (identifier: Q9BRV3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     95-148: Missing.

Show »
Length:167
Mass (Da):19,020
Checksum:iCCCDF3750BB71D12
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SR67Q5SR67_HUMAN
Sugar transporter SWEET1
SLC50A1
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WXX5A0A087WXX5_HUMAN
Sugar transporter SWEET1
SLC50A1
175Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3IS38A0A3B3IS38_HUMAN
Sugar transporter SWEET1
SLC50A1
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3IT24A0A3B3IT24_HUMAN
Sugar transporter SWEET1
SLC50A1
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ISS5A0A3B3ISS5_HUMAN
Sugar transporter SWEET1
SLC50A1
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ITH1A0A3B3ITH1_HUMAN
Sugar transporter SWEET1
SLC50A1
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF17233 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti43Q → R in AAF17232 (PubMed:10931946).Curated1
Sequence conflicti130G → A in CAG33429 (Ref. 3) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0349161 – 55Missing in isoform 2. 1 PublicationAdd BLAST55
Alternative sequenceiVSP_03491756 – 94GWLSY…YCPRK → MRGLHPWHVLRRPLGPQAHA NDPECGQRPVPALSHHGSQ in isoform 2. 1 PublicationAdd BLAST39
Alternative sequenceiVSP_03491895 – 148Missing in isoform 3. 1 PublicationAdd BLAST54

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF126023 mRNA Translation: AAF17232.1
AF126024 mRNA Translation: AAF17233.1 Frameshift.
AK289551 mRNA Translation: BAF82240.1
CR457148 mRNA Translation: CAG33429.1
AL691442 Genomic DNA No translation available.
BC005943 mRNA Translation: AAH05943.1
BC009621 mRNA Translation: AAH09621.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1093.1 [Q9BRV3-1]
CCDS44238.1 [Q9BRV3-3]
CCDS44239.1 [Q9BRV3-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001116309.1, NM_001122837.1 [Q9BRV3-2]
NP_001116311.1, NM_001122839.1 [Q9BRV3-3]
NP_001274515.1, NM_001287586.1
NP_001274516.1, NM_001287587.1
NP_001274517.1, NM_001287588.1
NP_001274519.1, NM_001287590.1
NP_001274520.1, NM_001287591.1
NP_001274521.1, NM_001287592.1
NP_061333.2, NM_018845.3 [Q9BRV3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000303343; ENSP00000306146; ENSG00000169241 [Q9BRV3-3]
ENST00000368401; ENSP00000357386; ENSG00000169241 [Q9BRV3-2]
ENST00000368404; ENSP00000357389; ENSG00000169241 [Q9BRV3-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55974

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55974

UCSC genome browser

More...
UCSCi
uc001fhj.5 human [Q9BRV3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF126023 mRNA Translation: AAF17232.1
AF126024 mRNA Translation: AAF17233.1 Frameshift.
AK289551 mRNA Translation: BAF82240.1
CR457148 mRNA Translation: CAG33429.1
AL691442 Genomic DNA No translation available.
BC005943 mRNA Translation: AAH05943.1
BC009621 mRNA Translation: AAH09621.1
CCDSiCCDS1093.1 [Q9BRV3-1]
CCDS44238.1 [Q9BRV3-3]
CCDS44239.1 [Q9BRV3-2]
RefSeqiNP_001116309.1, NM_001122837.1 [Q9BRV3-2]
NP_001116311.1, NM_001122839.1 [Q9BRV3-3]
NP_001274515.1, NM_001287586.1
NP_001274516.1, NM_001287587.1
NP_001274517.1, NM_001287588.1
NP_001274519.1, NM_001287590.1
NP_001274520.1, NM_001287591.1
NP_001274521.1, NM_001287592.1
NP_061333.2, NM_018845.3 [Q9BRV3-1]

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi121020, 2 interactors
IntActiQ9BRV3, 5 interactors
MINTiQ9BRV3
STRINGi9606.ENSP00000357389

Protein family/group databases

TCDBi2.A.123.1.4 the sweet, pq-loop, saliva, mtn3 (sweet) family

PTM databases

iPTMnetiQ9BRV3
PhosphoSitePlusiQ9BRV3

Polymorphism and mutation databases

BioMutaiSLC50A1
DMDMi74752289

Proteomic databases

MassIVEiQ9BRV3
PaxDbiQ9BRV3
PeptideAtlasiQ9BRV3
PRIDEiQ9BRV3
ProteomicsDBi78840 [Q9BRV3-1]
78841 [Q9BRV3-2]
78842 [Q9BRV3-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
3097 65 antibodies

The DNASU plasmid repository

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DNASUi
55974

Genome annotation databases

EnsembliENST00000303343; ENSP00000306146; ENSG00000169241 [Q9BRV3-3]
ENST00000368401; ENSP00000357386; ENSG00000169241 [Q9BRV3-2]
ENST00000368404; ENSP00000357389; ENSG00000169241 [Q9BRV3-1]
GeneIDi55974
KEGGihsa:55974
UCSCiuc001fhj.5 human [Q9BRV3-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55974
DisGeNETi55974

GeneCards: human genes, protein and diseases

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GeneCardsi
SLC50A1
HGNCiHGNC:30657 SLC50A1
HPAiENSG00000169241 Low tissue specificity
MIMi613683 gene
neXtProtiNX_Q9BRV3
OpenTargetsiENSG00000169241
PharmGKBiPA142671099

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1623 Eukaryota
ENOG4111M4R LUCA
GeneTreeiENSGT00390000007801
HOGENOMiCLU_048643_3_0_1
InParanoidiQ9BRV3
KOiK15382
OMAiIRFYLFW
OrthoDBi1116261at2759
PhylomeDBiQ9BRV3
TreeFamiTF313635

Enzyme and pathway databases

ReactomeiR-HSA-189200 Cellular hexose transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC50A1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55974
PharosiQ9BRV3 Tbio

Protein Ontology

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PROi
PR:Q9BRV3
RNActiQ9BRV3 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000169241 Expressed in right lobe of liver and 223 other tissues
ExpressionAtlasiQ9BRV3 baseline and differential
GenevisibleiQ9BRV3 HS

Family and domain databases

InterProiView protein in InterPro
IPR004316 SWEET_sugar_transpr
PfamiView protein in Pfam
PF03083 MtN3_slv, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSWET1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BRV3
Secondary accession number(s): Q5SR64
, Q6IAK6, Q96DC5, Q9UHQ2, Q9UHQ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: June 1, 2001
Last modified: April 22, 2020
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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