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Entry version 132 (18 Sep 2019)
Sequence version 3 (11 Jan 2011)
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Protein

Serine/threonine-protein phosphatase CPPED1

Gene

CPPED1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

a divalent metal cationBy similarityNote: Binds 2 divalent metal cations.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi53Divalent metal cation 1By similarity1
Metal bindingi90Divalent metal cation 1By similarity1
Metal bindingi90Divalent metal cation 2By similarity1
Metal bindingi127Divalent metal cation 2By similarity1
Metal bindingi247Divalent metal cation 2By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMetal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine/threonine-protein phosphatase CPPED1 (EC:3.1.3.16)
Alternative name(s):
Calcineurin-like phosphoesterase domain-containing protein 1
Complete S-transactivated protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CPPED1
Synonyms:CSTP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25632 CPPED1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615603 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BRF8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55313

Open Targets

More...
OpenTargetsi
ENSG00000103381

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164718110

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CPPED1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
317373448

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003205561 – 314Serine/threonine-protein phosphatase CPPED1Add BLAST314

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2PhosphoserineCombined sources1
Modified residuei294PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9BRF8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BRF8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BRF8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BRF8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BRF8

PeptideAtlas

More...
PeptideAtlasi
Q9BRF8

PRoteomics IDEntifications database

More...
PRIDEi
Q9BRF8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
78760 [Q9BRF8-1]
78761 [Q9BRF8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BRF8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BRF8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in subcutaneous adipose tissue.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression levels are slightly decreased in subcutaneous adipose tissue following weight loss. Expression levels may be not affected by preadipocyte differentiation.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Transactivated by the large envelope protein of the hepatitis B virus (HBV).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000103381 Expressed in 201 organ(s), highest expression level in leukocyte

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BRF8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040938
HPA041970

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
120595, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BRF8, 3 interactors

Molecular INTeraction database

More...
MINTi
Q9BRF8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000371193

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni47 – 250CatalyticAdd BLAST204

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IP70 Eukaryota
ENOG410ZI1D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008676

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000291782

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BRF8

KEGG Orthology (KO)

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KOi
K21814

Identification of Orthologs from Complete Genome Data

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OMAi
IGCQLGE

Database of Orthologous Groups

More...
OrthoDBi
908967at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BRF8

TreeFam database of animal gene trees

More...
TreeFami
TF329406

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07395 MPP_CSTP1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.60.21.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR041867 MPP_CSTP1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00149 Metallophos, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9BRF8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAAEAGGVF HRARGRTLAA FPAEKESEWK GPFYFILGAD PQFGLIKAWS
60 70 80 90 100
TGDCDNGGDE WEQEIRLTEQ AVQAINKLNP KPKFFVLCGD LIHAMPGKPW
110 120 130 140 150
RTEQTEDLKR VLRAVDRAIP LVLVSGNHDI GNTPTAETVE EFCRTWGDDY
160 170 180 190 200
FSFWVGGVLF LVLNSQFYEN PSKCPSLKQA QDQWLDEQLS IARQRHCQHA
210 220 230 240 250
IVFQHIPLFL ESIDEDDDYY FNLSKSTRKK LADKFIHAGV KVVFSGHYHR
260 270 280 290 300
NAGGTYQNLD MVVSSAIGCQ LGRDPHGLRV VVVTAEKIVH RYYSLDELSE
310
KGIEDDLMDL IKKK
Length:314
Mass (Da):35,548
Last modified:January 11, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD2DC770103053DA7
GO
Isoform 2 (identifier: Q9BRF8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     97-238: Missing.

Note: No experimental confirmation available.
Show »
Length:172
Mass (Da):19,036
Checksum:i63E35E20517FFCF7
GO
Isoform 3 (identifier: Q9BRF8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     97-122: GKPWRTEQTEDLKRVLRAVDRAIPLV → AGQRPPRAPSRGGHRRENCSPILQSR
     123-314: Missing.

Note: No experimental confirmation available.
Show »
Length:122
Mass (Da):13,462
Checksum:iA884324ECCA5FAF3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti47K → R in CAE45887 (PubMed:17974005).Curated1
Sequence conflicti77K → E in BAA92034 (PubMed:14702039).Curated1
Sequence conflicti148D → Y in BAB14194 (PubMed:14702039).Curated1
Sequence conflicti230K → E in BAA92034 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03920419A → D3 PublicationsCorresponds to variant dbSNP:rs3748976Ensembl.1
Natural variantiVAR_03920586V → I. Corresponds to variant dbSNP:rs3748980Ensembl.1
Natural variantiVAR_039206241K → RCombined sources4 PublicationsCorresponds to variant dbSNP:rs1713480Ensembl.1
Natural variantiVAR_039207290H → P. Corresponds to variant dbSNP:rs11645068Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03165897 – 238Missing in isoform 2. 1 PublicationAdd BLAST142
Alternative sequenceiVSP_05521897 – 122GKPWR…AIPLV → AGQRPPRAPSRGGHRRENCS PILQSR in isoform 3. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_055219123 – 314Missing in isoform 3. 1 PublicationAdd BLAST192

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY553877 mRNA Translation: AAS64575.1
AK002013 mRNA Translation: BAA92034.1
AK022710 mRNA Translation: BAB14194.1
AK298662 mRNA Translation: BAG60830.1
BX640805 mRNA Translation: CAE45887.1
AC010333 Genomic DNA No translation available.
AC092324 Genomic DNA No translation available.
AC109597 Genomic DNA No translation available.
BC006289 mRNA Translation: AAH06289.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42119.1 [Q9BRF8-2]
CCDS42120.1 [Q9BRF8-1]

NCBI Reference Sequences

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RefSeqi
NP_001092925.1, NM_001099455.1 [Q9BRF8-2]
NP_060810.2, NM_018340.2 [Q9BRF8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000261660; ENSP00000261660; ENSG00000103381 [Q9BRF8-3]
ENST00000381774; ENSP00000371193; ENSG00000103381 [Q9BRF8-1]
ENST00000433677; ENSP00000411127; ENSG00000103381 [Q9BRF8-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55313

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55313

UCSC genome browser

More...
UCSCi
uc002dca.5 human [Q9BRF8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY553877 mRNA Translation: AAS64575.1
AK002013 mRNA Translation: BAA92034.1
AK022710 mRNA Translation: BAB14194.1
AK298662 mRNA Translation: BAG60830.1
BX640805 mRNA Translation: CAE45887.1
AC010333 Genomic DNA No translation available.
AC092324 Genomic DNA No translation available.
AC109597 Genomic DNA No translation available.
BC006289 mRNA Translation: AAH06289.1
CCDSiCCDS42119.1 [Q9BRF8-2]
CCDS42120.1 [Q9BRF8-1]
RefSeqiNP_001092925.1, NM_001099455.1 [Q9BRF8-2]
NP_060810.2, NM_018340.2 [Q9BRF8-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi120595, 5 interactors
IntActiQ9BRF8, 3 interactors
MINTiQ9BRF8
STRINGi9606.ENSP00000371193

PTM databases

iPTMnetiQ9BRF8
PhosphoSitePlusiQ9BRF8

Polymorphism and mutation databases

BioMutaiCPPED1
DMDMi317373448

Proteomic databases

EPDiQ9BRF8
jPOSTiQ9BRF8
MassIVEiQ9BRF8
MaxQBiQ9BRF8
PaxDbiQ9BRF8
PeptideAtlasiQ9BRF8
PRIDEiQ9BRF8
ProteomicsDBi78760 [Q9BRF8-1]
78761 [Q9BRF8-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55313
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000261660; ENSP00000261660; ENSG00000103381 [Q9BRF8-3]
ENST00000381774; ENSP00000371193; ENSG00000103381 [Q9BRF8-1]
ENST00000433677; ENSP00000411127; ENSG00000103381 [Q9BRF8-2]
GeneIDi55313
KEGGihsa:55313
UCSCiuc002dca.5 human [Q9BRF8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55313
DisGeNETi55313

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CPPED1
HGNCiHGNC:25632 CPPED1
HPAiHPA040938
HPA041970
MIMi615603 gene
neXtProtiNX_Q9BRF8
OpenTargetsiENSG00000103381
PharmGKBiPA164718110

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IP70 Eukaryota
ENOG410ZI1D LUCA
GeneTreeiENSGT00390000008676
HOGENOMiHOG000291782
InParanoidiQ9BRF8
KOiK21814
OMAiIGCQLGE
OrthoDBi908967at2759
PhylomeDBiQ9BRF8
TreeFamiTF329406

Enzyme and pathway databases

ReactomeiR-HSA-6798695 Neutrophil degranulation

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55313

Pharos

More...
Pharosi
Q9BRF8

Protein Ontology

More...
PROi
PR:Q9BRF8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000103381 Expressed in 201 organ(s), highest expression level in leukocyte
GenevisibleiQ9BRF8 HS

Family and domain databases

CDDicd07395 MPP_CSTP1, 1 hit
Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR041867 MPP_CSTP1
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPPED_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BRF8
Secondary accession number(s): B4DQ68
, Q6MZY9, Q9H9M9, Q9NUT6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 11, 2011
Last modified: September 18, 2019
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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