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Entry version 123 (07 Oct 2020)
Sequence version 1 (01 Jun 2001)
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Protein

Coiled-coil domain-containing protein 77

Gene

CCDC77

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9BR77

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 77
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC77
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000120647.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28203, CCDC77

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BR77

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84318

Open Targets

More...
OpenTargetsi
ENSG00000120647

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485429

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BR77, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC77

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74732846

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002710031 – 488Coiled-coil domain-containing protein 77Add BLAST488

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei36PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki51Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BR77

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BR77

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BR77

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BR77

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BR77

PeptideAtlas

More...
PeptideAtlasi
Q9BR77

PRoteomics IDEntifications database

More...
PRIDEi
Q9BR77

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
78747 [Q9BR77-1]
78748 [Q9BR77-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BR77

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BR77

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000120647, Expressed in oocyte and 162 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BR77, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BR77, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000120647, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124044, 52 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BR77, 49 interactors

Molecular INTeraction database

More...
MINTi
Q9BR77

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000239830

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BR77, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BR77

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili55 – 118Sequence analysisAdd BLAST64
Coiled coili208 – 488Sequence analysisAdd BLAST281

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QT8A, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010251

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_035281_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BR77

KEGG Orthology (KO)

More...
KOi
K16757

Identification of Orthologs from Complete Genome Data

More...
OMAi
QYRVQCK

Database of Orthologous Groups

More...
OrthoDBi
1565693at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BR77

TreeFam database of animal gene trees

More...
TreeFami
TF329022

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037696, CCDC77

The PANTHER Classification System

More...
PANTHERi
PTHR22091, PTHR22091, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BR77-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNFTPTHTPV CRKRTVVSKR GVAVSGPTKR RGMADSLEST PLPSPEDRLA
60 70 80 90 100
KLHPSKELLE YYQKKMAECE AENEDLLKKL ELYKEACEGQ HKLECDLQQR
110 120 130 140 150
EEEIAELQKA LSDMQVCLFQ EREHVLRLYS ENDRLRIREL EDKKKIQNLL
160 170 180 190 200
ALVGTDAGEV TYFCKEPPHK VTILQKTIQA VGECEQSESS AFKADPKISK
210 220 230 240 250
RRPSRERKES SEHYQRDIQT LILQVEALQA QLGEQTKLSR EQIEGLIEDR
260 270 280 290 300
RIHLEEIQVQ HQRNQNKIKE LTKNLHHTQE LLYESTKDFL QLRSENQNKE
310 320 330 340 350
KSWMLEKDNL MSKIKQYRVQ CKKKEDKIGK VLPVMHESHH AQSEYIKSLK
360 370 380 390 400
DKLVQEKKLS NMYQEQCISL EEELARIREE EGMRREIFKD RTNKMGKRLQ
410 420 430 440 450
IMTKRYEALE RRRILEVEGF KTDIKVLRQK LKDLEQMLYK ATVNARANQD
460 470 480
LALLCEVRDS NRRAHKIQGE LKNLKSKVFG LENELRLC
Length:488
Mass (Da):57,486
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i845D0113DA64889F
GO
Isoform 2 (identifier: Q9BR77-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-32: Missing.

Show »
Length:456
Mass (Da):53,979
Checksum:i7F34902E11711A45
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H0W5F5H0W5_HUMAN
Coiled-coil domain-containing prote...
CCDC77
386Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H5Q8F5H5Q8_HUMAN
Coiled-coil domain-containing prote...
CCDC77
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02983825S → R. Corresponds to variant dbSNP:rs4980895Ensembl.1
Natural variantiVAR_029839335M → T. Corresponds to variant dbSNP:rs735295Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0431351 – 32Missing in isoform 2. 1 PublicationAdd BLAST32

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027638 mRNA Translation: BAB55255.1
AK293165 mRNA Translation: BAG56709.1
AK316029 mRNA Translation: BAH14400.1
AC005844 Genomic DNA No translation available.
CH471116 Genomic DNA Translation: EAW88967.1
BC006444 mRNA Translation: AAH06444.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44781.1 [Q9BR77-2]
CCDS8503.1 [Q9BR77-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001123618.1, NM_001130146.1 [Q9BR77-2]
NP_001123619.1, NM_001130147.1 [Q9BR77-2]
NP_001123620.1, NM_001130148.1 [Q9BR77-2]
NP_115734.1, NM_032358.3 [Q9BR77-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000239830; ENSP00000239830; ENSG00000120647 [Q9BR77-1]
ENST00000412006; ENSP00000412925; ENSG00000120647 [Q9BR77-2]
ENST00000422000; ENSP00000391870; ENSG00000120647 [Q9BR77-2]
ENST00000540180; ENSP00000440554; ENSG00000120647 [Q9BR77-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84318

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84318

UCSC genome browser

More...
UCSCi
uc001qig.4, human [Q9BR77-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027638 mRNA Translation: BAB55255.1
AK293165 mRNA Translation: BAG56709.1
AK316029 mRNA Translation: BAH14400.1
AC005844 Genomic DNA No translation available.
CH471116 Genomic DNA Translation: EAW88967.1
BC006444 mRNA Translation: AAH06444.1
CCDSiCCDS44781.1 [Q9BR77-2]
CCDS8503.1 [Q9BR77-1]
RefSeqiNP_001123618.1, NM_001130146.1 [Q9BR77-2]
NP_001123619.1, NM_001130147.1 [Q9BR77-2]
NP_001123620.1, NM_001130148.1 [Q9BR77-2]
NP_115734.1, NM_032358.3 [Q9BR77-1]

3D structure databases

SMRiQ9BR77
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124044, 52 interactors
IntActiQ9BR77, 49 interactors
MINTiQ9BR77
STRINGi9606.ENSP00000239830

PTM databases

iPTMnetiQ9BR77
PhosphoSitePlusiQ9BR77

Polymorphism and mutation databases

BioMutaiCCDC77
DMDMi74732846

Proteomic databases

EPDiQ9BR77
jPOSTiQ9BR77
MassIVEiQ9BR77
MaxQBiQ9BR77
PaxDbiQ9BR77
PeptideAtlasiQ9BR77
PRIDEiQ9BR77
ProteomicsDBi78747 [Q9BR77-1]
78748 [Q9BR77-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
50661, 10 antibodies

Genome annotation databases

EnsembliENST00000239830; ENSP00000239830; ENSG00000120647 [Q9BR77-1]
ENST00000412006; ENSP00000412925; ENSG00000120647 [Q9BR77-2]
ENST00000422000; ENSP00000391870; ENSG00000120647 [Q9BR77-2]
ENST00000540180; ENSP00000440554; ENSG00000120647 [Q9BR77-2]
GeneIDi84318
KEGGihsa:84318
UCSCiuc001qig.4, human [Q9BR77-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84318
DisGeNETi84318
EuPathDBiHostDB:ENSG00000120647.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC77
HGNCiHGNC:28203, CCDC77
HPAiENSG00000120647, Low tissue specificity
neXtProtiNX_Q9BR77
OpenTargetsiENSG00000120647
PharmGKBiPA143485429

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QT8A, Eukaryota
GeneTreeiENSGT00390000010251
HOGENOMiCLU_035281_0_0_1
InParanoidiQ9BR77
KOiK16757
OMAiQYRVQCK
OrthoDBi1565693at2759
PhylomeDBiQ9BR77
TreeFamiTF329022

Enzyme and pathway databases

PathwayCommonsiQ9BR77

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
84318, 19 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC77, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84318
PharosiQ9BR77, Tdark

Protein Ontology

More...
PROi
PR:Q9BR77
RNActiQ9BR77, protein

Gene expression databases

BgeeiENSG00000120647, Expressed in oocyte and 162 other tissues
ExpressionAtlasiQ9BR77, baseline and differential
GenevisibleiQ9BR77, HS

Family and domain databases

InterProiView protein in InterPro
IPR037696, CCDC77
PANTHERiPTHR22091, PTHR22091, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCD77_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BR77
Secondary accession number(s): B4DDE8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2001
Last modified: October 7, 2020
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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