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Protein

Zinc finger SWIM domain-containing protein 1

Gene

ZSWIM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri363 – 405SWIM-typePROSITE-ProRule annotationAdd BLAST43

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLinkiQ9BR11

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 1
Gene namesi
Name:ZSWIM1
Synonyms:C20orf162
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000168612.4
HGNCiHGNC:16155 ZSWIM1
neXtProtiNX_Q9BR11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168612
PharmGKBiPA25704

Polymorphism and mutation databases

BioMutaiZSWIM1
DMDMi73920980

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002230951 – 485Zinc finger SWIM domain-containing protein 1Add BLAST485

Proteomic databases

MaxQBiQ9BR11
PaxDbiQ9BR11
PeptideAtlasiQ9BR11
PRIDEiQ9BR11
ProteomicsDBi78737

PTM databases

iPTMnetiQ9BR11
PhosphoSitePlusiQ9BR11

Expressioni

Gene expression databases

BgeeiENSG00000168612
CleanExiHS_ZSWIM1
GenevisibleiQ9BR11 HS

Organism-specific databases

HPAiHPA041147
HPA046751

Interactioni

Protein-protein interaction databases

BioGridi124678, 1 interactor
IntActiQ9BR11, 4 interactors
MINTiQ9BR11

Structurei

3D structure databases

ProteinModelPortaliQ9BR11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri363 – 405SWIM-typePROSITE-ProRule annotationAdd BLAST43

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IK5N Eukaryota
ENOG4111FY6 LUCA
GeneTreeiENSGT00390000017273
HOGENOMiHOG000231003
HOVERGENiHBG099855
InParanoidiQ9BR11
OMAiIWLAHRW
OrthoDBiEOG091G01A2
PhylomeDBiQ9BR11
TreeFamiTF335703

Family and domain databases

InterProiView protein in InterPro
IPR007527 Znf_SWIM
PfamiView protein in Pfam
PF04434 SWIM, 1 hit
PROSITEiView protein in PROSITE
PS50966 ZF_SWIM, 1 hit

Sequencei

Sequence statusi: Complete.

Q9BR11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLERLKAPWS AALQRKYFDL GIWTAPISPM ALTMLNGLLI KDSSPPMLLH
60 70 80 90 100
QVNKTAQLDT FNYQSCFMQS VFDHFPEILF IHRTYNPRGK VLYTFLVDGP
110 120 130 140 150
RVQLEGHLAR AVYFAIPAKE DTEGLAQMFQ VFKKFNPAWE RVCTILVDPH
160 170 180 190 200
FLPLPILAME FPTAEVLLSA FHICKFLQAK FYQLSLERPV ERLLLTSLQS
210 220 230 240 250
TMCSATAGNL RKLYTLLSNC IPPAKLPELH SHWLLNDRIW LAHRWRSRAE
260 270 280 290 300
SSHYFQSLEV TTHILSQFFG TTPSEKQGMA SLFRYMQQNS ADKANFNQGL
310 320 330 340 350
CAQNNHAPSD TIPESPKLEQ LVESHIQHSL NAICTGPAAQ LCLGELAVVQ
360 370 380 390 400
KSTHLIGSGS EKMNIQILED THKVQPQPPA SCSCYFNQAF HLPCRHILAM
410 420 430 440 450
LSARRQVLQP DMLPAQWTAG CATSLDSILG SKWSETLDKH LAVTHLTEEV
460 470 480
GQLLQHCTKE EFERRYSTLR ELADSWIGPY EQVQL
Length:485
Mass (Da):55,071
Last modified:August 30, 2005 - v2
Checksum:iF7447E98EFC6FD6E
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_020445101R → Q. Corresponds to variant dbSNP:rs3746500Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL008726 Genomic DNA No translation available.
BC001672 mRNA Translation: AAH01672.3
BC080525 mRNA Translation: AAH80525.2
CCDSiCCDS13382.2
RefSeqiNP_542170.3, NM_080603.4
XP_005260667.1, XM_005260610.4
XP_005260668.1, XM_005260611.4
XP_011527402.1, XM_011529100.2
UniGeneiHs.517075

Genome annotation databases

EnsembliENST00000372520; ENSP00000361598; ENSG00000168612
ENST00000372523; ENSP00000361601; ENSG00000168612
GeneIDi90204
KEGGihsa:90204
UCSCiuc010ghi.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiZSWM1_HUMAN
AccessioniPrimary (citable) accession number: Q9BR11
Secondary accession number(s): Q5JZH2, Q9BR12, Q9BV30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: August 30, 2005
Last modified: June 20, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

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