UniProtKB - Q9BR11 (ZSWM1_HUMAN)
Protein
Zinc finger SWIM domain-containing protein 1
Gene
ZSWIM1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 363 – 405 | SWIM-typePROSITE-ProRule annotationAdd BLAST | 43 |
GO - Molecular functioni
- zinc ion binding Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | Q9BR11 |
SignaLinki | Q9BR11 |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger SWIM domain-containing protein 1 |
Gene namesi | Name:ZSWIM1 Synonyms:C20orf162 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16155, ZSWIM1 |
neXtProti | NX_Q9BR11 |
VEuPathDBi | HostDB:ENSG00000168612.4 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000168612 |
PharmGKBi | PA25704 |
Miscellaneous databases
Pharosi | Q9BR11, Tdark |
Genetic variation databases
BioMutai | ZSWIM1 |
DMDMi | 73920980 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000223095 | 1 – 485 | Zinc finger SWIM domain-containing protein 1Add BLAST | 485 |
Proteomic databases
EPDi | Q9BR11 |
MassIVEi | Q9BR11 |
MaxQBi | Q9BR11 |
PaxDbi | Q9BR11 |
PeptideAtlasi | Q9BR11 |
PRIDEi | Q9BR11 |
ProteomicsDBi | 78737 |
PTM databases
iPTMneti | Q9BR11 |
PhosphoSitePlusi | Q9BR11 |
Expressioni
Gene expression databases
Bgeei | ENSG00000168612, Expressed in cerebellum and 150 other tissues |
Genevisiblei | Q9BR11, HS |
Organism-specific databases
HPAi | ENSG00000168612, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 124678, 2 interactors |
IntActi | Q9BR11, 4 interactors |
MINTi | Q9BR11 |
Miscellaneous databases
RNActi | Q9BR11, protein |
Family & Domainsi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 363 – 405 | SWIM-typePROSITE-ProRule annotationAdd BLAST | 43 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | ENOG502RNJT, Eukaryota |
GeneTreei | ENSGT00390000017273 |
HOGENOMi | CLU_563302_0_0_1 |
InParanoidi | Q9BR11 |
OMAi | CKFLQGK |
OrthoDBi | 338340at2759 |
PhylomeDBi | Q9BR11 |
TreeFami | TF335703 |
Family and domain databases
InterProi | View protein in InterPro IPR007527, Znf_SWIM IPR040303, ZSWIM1 |
PANTHERi | PTHR31569:SF0, PTHR31569:SF0, 1 hit |
Pfami | View protein in Pfam PF04434, SWIM, 1 hit |
PROSITEi | View protein in PROSITE PS50966, ZF_SWIM, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9BR11-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLERLKAPWS AALQRKYFDL GIWTAPISPM ALTMLNGLLI KDSSPPMLLH
60 70 80 90 100
QVNKTAQLDT FNYQSCFMQS VFDHFPEILF IHRTYNPRGK VLYTFLVDGP
110 120 130 140 150
RVQLEGHLAR AVYFAIPAKE DTEGLAQMFQ VFKKFNPAWE RVCTILVDPH
160 170 180 190 200
FLPLPILAME FPTAEVLLSA FHICKFLQAK FYQLSLERPV ERLLLTSLQS
210 220 230 240 250
TMCSATAGNL RKLYTLLSNC IPPAKLPELH SHWLLNDRIW LAHRWRSRAE
260 270 280 290 300
SSHYFQSLEV TTHILSQFFG TTPSEKQGMA SLFRYMQQNS ADKANFNQGL
310 320 330 340 350
CAQNNHAPSD TIPESPKLEQ LVESHIQHSL NAICTGPAAQ LCLGELAVVQ
360 370 380 390 400
KSTHLIGSGS EKMNIQILED THKVQPQPPA SCSCYFNQAF HLPCRHILAM
410 420 430 440 450
LSARRQVLQP DMLPAQWTAG CATSLDSILG SKWSETLDKH LAVTHLTEEV
460 470 480
GQLLQHCTKE EFERRYSTLR ELADSWIGPY EQVQL
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_020445 | 101 | R → Q. Corresponds to variant dbSNP:rs3746500Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL008726 Genomic DNA No translation available. BC001672 mRNA Translation: AAH01672.3 BC080525 mRNA Translation: AAH80525.2 |
CCDSi | CCDS13382.2 |
RefSeqi | NP_542170.3, NM_080603.4 XP_005260667.1, XM_005260610.4 XP_005260668.1, XM_005260611.4 XP_011527402.1, XM_011529100.2 |
Genome annotation databases
Ensembli | ENST00000372520; ENSP00000361598; ENSG00000168612 ENST00000372523; ENSP00000361601; ENSG00000168612 |
GeneIDi | 90204 |
KEGGi | hsa:90204 |
UCSCi | uc010ghi.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL008726 Genomic DNA No translation available. BC001672 mRNA Translation: AAH01672.3 BC080525 mRNA Translation: AAH80525.2 |
CCDSi | CCDS13382.2 |
RefSeqi | NP_542170.3, NM_080603.4 XP_005260667.1, XM_005260610.4 XP_005260668.1, XM_005260611.4 XP_011527402.1, XM_011529100.2 |
3D structure databases
SMRi | Q9BR11 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 124678, 2 interactors |
IntActi | Q9BR11, 4 interactors |
MINTi | Q9BR11 |
PTM databases
iPTMneti | Q9BR11 |
PhosphoSitePlusi | Q9BR11 |
Genetic variation databases
BioMutai | ZSWIM1 |
DMDMi | 73920980 |
Proteomic databases
EPDi | Q9BR11 |
MassIVEi | Q9BR11 |
MaxQBi | Q9BR11 |
PaxDbi | Q9BR11 |
PeptideAtlasi | Q9BR11 |
PRIDEi | Q9BR11 |
ProteomicsDBi | 78737 |
Protocols and materials databases
Antibodypediai | 27817, 77 antibodies |
Genome annotation databases
Ensembli | ENST00000372520; ENSP00000361598; ENSG00000168612 ENST00000372523; ENSP00000361601; ENSG00000168612 |
GeneIDi | 90204 |
KEGGi | hsa:90204 |
UCSCi | uc010ghi.4, human |
Organism-specific databases
CTDi | 90204 |
GeneCardsi | ZSWIM1 |
HGNCi | HGNC:16155, ZSWIM1 |
HPAi | ENSG00000168612, Low tissue specificity |
neXtProti | NX_Q9BR11 |
OpenTargetsi | ENSG00000168612 |
PharmGKBi | PA25704 |
VEuPathDBi | HostDB:ENSG00000168612.4 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RNJT, Eukaryota |
GeneTreei | ENSGT00390000017273 |
HOGENOMi | CLU_563302_0_0_1 |
InParanoidi | Q9BR11 |
OMAi | CKFLQGK |
OrthoDBi | 338340at2759 |
PhylomeDBi | Q9BR11 |
TreeFami | TF335703 |
Enzyme and pathway databases
PathwayCommonsi | Q9BR11 |
SignaLinki | Q9BR11 |
Miscellaneous databases
BioGRID-ORCSi | 90204, 2 hits in 999 CRISPR screens |
ChiTaRSi | ZSWIM1, human |
GenomeRNAii | 90204 |
Pharosi | Q9BR11, Tdark |
PROi | PR:Q9BR11 |
RNActi | Q9BR11, protein |
Gene expression databases
Bgeei | ENSG00000168612, Expressed in cerebellum and 150 other tissues |
Genevisiblei | Q9BR11, HS |
Family and domain databases
InterProi | View protein in InterPro IPR007527, Znf_SWIM IPR040303, ZSWIM1 |
PANTHERi | PTHR31569:SF0, PTHR31569:SF0, 1 hit |
Pfami | View protein in Pfam PF04434, SWIM, 1 hit |
PROSITEi | View protein in PROSITE PS50966, ZF_SWIM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZSWM1_HUMAN | |
Accessioni | Q9BR11Primary (citable) accession number: Q9BR11 Secondary accession number(s): Q5JZH2, Q9BR12, Q9BV30 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 25, 2003 |
Last sequence update: | August 30, 2005 | |
Last modified: | April 7, 2021 | |
This is version 130 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports