ZSWIM1

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	363 – 405	SWIM-typePROSITE-ProRule annotationAdd BLAST		43

GO - Molecular functionⁱ

zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkⁱ	Q9BR11

SignaLinkⁱ

Q9BR11

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger SWIM domain-containing protein 1
Gene namesⁱ	Name:ZSWIM1 Synonyms:C20orf162
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 20

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000168612.4
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:16155 ZSWIM1
neXtProtⁱ	NX_Q9BR11

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000168612
PharmGKBⁱ	PA25704

Polymorphism and mutation databases

BioMutaⁱ	ZSWIM1
DMDMⁱ	73920980

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000223095	1 – 485	Zinc finger SWIM domain-containing protein 1Add BLAST		485

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9BR11
PaxDbⁱ	Q9BR11
PeptideAtlas More...PeptideAtlasⁱ	Q9BR11
PRIDEⁱ	Q9BR11
ProteomicsDBⁱ	78737

PTM databases

iPTMnetⁱ	Q9BR11
PhosphoSitePlusⁱ	Q9BR11

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000168612
CleanExⁱ	HS_ZSWIM1
Genevisibleⁱ	Q9BR11 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA041147 HPA046751

HPAⁱ

HPA041147
HPA046751

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	124678, 1 interactor
IntActⁱ	Q9BR11, 4 interactors
Molecular INTeraction database More...MINTⁱ	Q9BR11

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9BR11
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	363 – 405	SWIM-typePROSITE-ProRule annotationAdd BLAST		43

Keywords - Domainⁱ

Zinc-finger

Phylogenomic databases

eggNOGⁱ	ENOG410IK5N Eukaryota ENOG4111FY6 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000017273
HOGENOMⁱ	HOG000231003
HOVERGENⁱ	HBG099855
InParanoidⁱ	Q9BR11
OMAⁱ	IWLAHRW
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G01A2
PhylomeDBⁱ	Q9BR11
TreeFamⁱ	TF335703

Family and domain databases

InterProⁱ	View protein in InterPro IPR007527 Znf_SWIM
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04434 SWIM, 1 hit
PROSITEⁱ	View protein in PROSITE PS50966 ZF_SWIM, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9BR11-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLERLKAPWS AALQRKYFDL GIWTAPISPM ALTMLNGLLI KDSSPPMLLH 
        60         70         80         90        100
QVNKTAQLDT FNYQSCFMQS VFDHFPEILF IHRTYNPRGK VLYTFLVDGP 
       110        120        130        140        150
RVQLEGHLAR AVYFAIPAKE DTEGLAQMFQ VFKKFNPAWE RVCTILVDPH 
       160        170        180        190        200
FLPLPILAME FPTAEVLLSA FHICKFLQAK FYQLSLERPV ERLLLTSLQS 
       210        220        230        240        250
TMCSATAGNL RKLYTLLSNC IPPAKLPELH SHWLLNDRIW LAHRWRSRAE 
       260        270        280        290        300
SSHYFQSLEV TTHILSQFFG TTPSEKQGMA SLFRYMQQNS ADKANFNQGL 
       310        320        330        340        350
CAQNNHAPSD TIPESPKLEQ LVESHIQHSL NAICTGPAAQ LCLGELAVVQ 
       360        370        380        390        400
KSTHLIGSGS EKMNIQILED THKVQPQPPA SCSCYFNQAF HLPCRHILAM 
       410        420        430        440        450
LSARRQVLQP DMLPAQWTAG CATSLDSILG SKWSETLDKH LAVTHLTEEV 
       460        470        480 
GQLLQHCTKE EFERRYSTLR ELADSWIGPY EQVQL

Length:485

Mass (Da):55,071

Last modified:August 30, 2005 - v2

Checksum:ⁱF7447E98EFC6FD6E

GO

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_020445	101	R → Q. Corresponds to variant dbSNP:rs3746500Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL008726 Genomic DNA No translation available. BC001672 mRNA Translation: AAH01672.3 BC080525 mRNA Translation: AAH80525.2
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS13382.2
NCBI Reference Sequences More...RefSeqⁱ	NP_542170.3, NM_080603.4 XP_005260667.1, XM_005260610.4 XP_005260668.1, XM_005260611.4 XP_011527402.1, XM_011529100.2
UniGeneⁱ	Hs.517075

Genome annotation databases

Ensemblⁱ	ENST00000372520; ENSP00000361598; ENSG00000168612 ENST00000372523; ENSP00000361601; ENSG00000168612
GeneIDⁱ	90204
KEGGⁱ	hsa:90204
UCSC genome browser More...UCSCⁱ	uc010ghi.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Protein	Similar proteins		Species	Score	Length
Q9BR11	cDNA FLJ77289, highly similar to Homo sapiens zinc finger, SWIM domain containing 1 (ZSWIM1), mRNA		HUMAN		456
Zinc finger SWIM-type containing 1		MACMU		486
Zinc finger SWIM-type containing 1		MACFA		486
Zinc finger SWIM-type containing 1		MACNE		486
Zinc finger SWIM-type containing 1		COLAP		486
+30

Protein	Similar proteins		Species	Score	Length
Q9BR11	cDNA FLJ77289, highly similar to Homo sapiens zinc finger, SWIM domain containing 1 (ZSWIM1), mRNA		HUMAN		456
Zinc finger SWIM-type containing 1		MACMU		486
Zinc finger SWIM-type containing 1		MACFA		486
Zinc finger SWIM-type containing 1		MACNE		486
Zinc finger SWIM-type containing 1		GORGO		486
+85

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL008726 Genomic DNA No translation available. BC001672 mRNA Translation: AAH01672.3 BC080525 mRNA Translation: AAH80525.2
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS13382.2
NCBI Reference Sequences More...RefSeqⁱ	NP_542170.3, NM_080603.4 XP_005260667.1, XM_005260610.4 XP_005260668.1, XM_005260611.4 XP_011527402.1, XM_011529100.2
UniGeneⁱ	Hs.517075

3D structure databases

ProteinModelPortalⁱ	Q9BR11
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	124678, 1 interactor
IntActⁱ	Q9BR11, 4 interactors
Molecular INTeraction database More...MINTⁱ	Q9BR11

PTM databases

iPTMnetⁱ	Q9BR11
PhosphoSitePlusⁱ	Q9BR11

Polymorphism and mutation databases

BioMutaⁱ	ZSWIM1
DMDMⁱ	73920980

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9BR11
PaxDbⁱ	Q9BR11
PeptideAtlas More...PeptideAtlasⁱ	Q9BR11
PRIDEⁱ	Q9BR11
ProteomicsDBⁱ	78737

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000372520; ENSP00000361598; ENSG00000168612 ENST00000372523; ENSP00000361601; ENSG00000168612
GeneIDⁱ	90204
KEGGⁱ	hsa:90204
UCSC genome browser More...UCSCⁱ	uc010ghi.4 human

Organism-specific databases

CTDⁱ	90204
EuPathDBⁱ	HostDB:ENSG00000168612.4
GeneCardsⁱ	ZSWIM1
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:16155 ZSWIM1
Human Protein Atlas More...HPAⁱ	HPA041147 HPA046751
neXtProtⁱ	NX_Q9BR11
Open Targets More...OpenTargetsⁱ	ENSG00000168612
PharmGKBⁱ	PA25704
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IK5N Eukaryota ENOG4111FY6 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000017273
HOGENOMⁱ	HOG000231003
HOVERGENⁱ	HBG099855
InParanoidⁱ	Q9BR11
OMAⁱ	IWLAHRW
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G01A2
PhylomeDBⁱ	Q9BR11
TreeFamⁱ	TF335703

Enzyme and pathway databases

SignaLinkⁱ	Q9BR11

SignaLinkⁱ

Q9BR11

Miscellaneous databases

ChiTaRSⁱ	ZSWIM1 human
GenomeRNAiⁱ	90204
Protein Ontology More...PROⁱ	PR:Q9BR11

Gene expression databases

Bgeeⁱ	ENSG00000168612
CleanExⁱ	HS_ZSWIM1
Genevisibleⁱ	Q9BR11 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR007527 Znf_SWIM
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04434 SWIM, 1 hit
PROSITEⁱ	View protein in PROSITE PS50966 ZF_SWIM, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZSWM1_HUMAN
Accessionⁱ	Q9BR11Primary (citable) accession number: Q9BR11 Secondary accession number(s): Q5JZH2, Q9BR12, Q9BV30
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
	Last sequence update:	August 30, 2005
	Last modified:	June 20, 2018
	This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations

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UniParc

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UniRef

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Supporting data

UniProtKB - Q9BR11 (ZSWM1_HUMAN)

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Zinc finger SWIM domain-containing protein 1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Phylogenomic databases

Family and domain databases

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ