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Entry version 156 (12 Aug 2020)
Sequence version 3 (05 Apr 2011)
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Protein

Dysbindin domain-containing protein 2

Gene

DBNDD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • negative regulation of protein kinase activity Source: UniProtKB

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9BQY9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dysbindin domain-containing protein 2
Alternative name(s):
Casein kinase-1 binding protein
Short name:
CK1BP
HSMNP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DBNDD2
Synonyms:C20orf35
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000244274.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15881, DBNDD2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611453, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BQY9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55861

Open Targets

More...
OpenTargetsi
ENSG00000244274

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25749

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BQY9, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DBNDD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
327478587

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001910031 – 259Dysbindin domain-containing protein 2Add BLAST259

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei217PhosphoserineBy similarity1
Modified residuei218PhosphoserineBy similarity1
Modified residuei237PhosphothreonineBy similarity1
Modified residuei242PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BQY9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BQY9

PeptideAtlas

More...
PeptideAtlasi
Q9BQY9

PRoteomics IDEntifications database

More...
PRIDEi
Q9BQY9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
63697
78730 [Q9BQY9-1]
78731 [Q9BQY9-2]
78732 [Q9BQY9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BQY9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BQY9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000244274, Expressed in C1 segment of cervical spinal cord and 115 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BQY9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BQY9, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000244274, Tissue enhanced (brain, skeletal muscle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

Interacts with CSNK1D and CSNK1E.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120963, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BQY9, 4 interactors

Molecular INTeraction database

More...
MINTi
Q9BQY9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000361795

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BQY9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BQY9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 38Poly-Pro6
Compositional biasi214 – 222Poly-Ser9
Compositional biasi244 – 247Poly-Glu4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dysbindin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RZ1K, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161212

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_097594_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BQY9

Identification of Orthologs from Complete Genome Data

More...
OMAi
LEQMDMM

Database of Orthologous Groups

More...
OrthoDBi
862376at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BQY9

TreeFam database of animal gene trees

More...
TreeFami
TF332997

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007531, Dysbindin

The PANTHER Classification System

More...
PANTHERi
PTHR16294, PTHR16294, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04440, Dysbindin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BQY9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGAGNFLTAL EVPVAALAGA ASDRRASCER VSPPPPLPHF RLPPLPRSRL
60 70 80 90 100
PGPVSRPEPG APLLGCWLQW GAPSPGPLCL LFRLCSCTCF APLPAGADMD
110 120 130 140 150
PNPRAALERQ QLRLRERQKF FEDILQPETE FVFPLSHLHL ESQRPPIGSI
160 170 180 190 200
SSMEVNVDTL EQVELIDLGD PDAADVFLPC EDPPPTPQSS GMDNHLEELS
210 220 230 240 250
LPVPTSDRTT SRTSSSSSSD SSTNLHSPNP SDDGADTPLA QSDEEEERGD

GGAEPGACS
Length:259
Mass (Da):27,671
Last modified:April 5, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA1F062426867A2C
GO
Isoform 2 (identifier: Q9BQY9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-98: Missing.

Show »
Length:161
Mass (Da):17,525
Checksum:i6840B7093720567B
GO
Isoform 3 (identifier: Q9BQY9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-98: Missing.
     193-210: DNHLEELSLPVPTSDRTT → PLCFGDFSASQPEPDVRL
     211-259: Missing.

Show »
Length:112
Mass (Da):12,614
Checksum:iBB2C19A23C184395
GO
Isoform 4 (identifier: Q9BQY9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-53: MGAGNFLTAL...PLPRSRLPGP → MESWALAVFP...GRGKRSPRAE

Show »
Length:263
Mass (Da):28,785
Checksum:iB14539919D137982
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y7N7H0Y7N7_HUMAN
Dysbindin domain-containing protein...
DBNDD2
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti43P → GTR in AAF67656 (PubMed:10931946).Curated1
Sequence conflicti162Q → H in BAA91235 (PubMed:14702039).Curated1
Sequence conflicti192M → V in AAF67656 (PubMed:10931946).Curated1
Sequence conflicti192M → V in AAM77463 (PubMed:16305340).Curated1
Sequence conflicti192M → V in BAA91235 (PubMed:14702039).Curated1
Sequence conflicti192M → V in EAW75854 (Ref. 6) Curated1
Sequence conflicti192M → V in EAW75848 (Ref. 6) Curated1
Sequence conflicti192M → V in AAH12818 (PubMed:15489334).Curated1
Sequence conflicti192M → V in AAH01105 (PubMed:15489334).Curated1
Sequence conflicti204P → A in AAF67656 (PubMed:10931946).Curated1
Sequence conflicti249G → D in BAA91235 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0077531 – 98Missing in isoform 2 and isoform 3. 3 PublicationsAdd BLAST98
Alternative sequenceiVSP_0466911 – 53MGAGN…RLPGP → MESWALAVFPEYRVSLLWCL ELASPLWSLGQAPPLHETWF VGHTWFQGRGKRSPRAE in isoform 4. CuratedAdd BLAST53
Alternative sequenceiVSP_040767193 – 210DNHLE…SDRTT → PLCFGDFSASQPEPDVRL in isoform 3. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_040768211 – 259Missing in isoform 3. 1 PublicationAdd BLAST49

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF220191 mRNA Translation: AAF67656.1
AY113697 mRNA Translation: AAM77463.1
AK000531 mRNA Translation: BAA91235.1
AJ276469 mRNA Translation: CAB83042.1
AL021578 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75848.1
CH471077 Genomic DNA Translation: EAW75854.1
AL591565 mRNA Translation: CAC39141.1
BC001105 mRNA Translation: AAH01105.1
BC012818 mRNA Translation: AAH12818.1
BG703352 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42880.1 [Q9BQY9-2]
CCDS42881.1 [Q9BQY9-3]
CCDS56193.1 [Q9BQY9-1]
CCDS56194.1 [Q9BQY9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001041686.1, NM_001048221.2 [Q9BQY9-2]
NP_001041687.1, NM_001048222.2 [Q9BQY9-3]
NP_001041688.1, NM_001048223.2 [Q9BQY9-2]
NP_001041689.1, NM_001048224.2 [Q9BQY9-3]
NP_001041690.2, NM_001048225.2 [Q9BQY9-2]
NP_001184068.1, NM_001197139.1 [Q9BQY9-2]
NP_001184069.1, NM_001197140.1 [Q9BQY9-2]
NP_060948.3, NM_018478.3 [Q9BQY9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000357275; ENSP00000349822; ENSG00000244274 [Q9BQY9-2]
ENST00000360981; ENSP00000354250; ENSG00000244274 [Q9BQY9-2]
ENST00000372710; ENSP00000361795; ENSG00000244274 [Q9BQY9-4]
ENST00000372712; ENSP00000361797; ENSG00000244274 [Q9BQY9-2]
ENST00000372717; ENSP00000361802; ENSG00000244274 [Q9BQY9-3]
ENST00000372720; ENSP00000361805; ENSG00000244274 [Q9BQY9-1]
ENST00000372722; ENSP00000361807; ENSG00000244274 [Q9BQY9-3]
ENST00000372723; ENSP00000361808; ENSG00000244274 [Q9BQY9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55861

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55861

UCSC genome browser

More...
UCSCi
uc002xnz.4, human [Q9BQY9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF220191 mRNA Translation: AAF67656.1
AY113697 mRNA Translation: AAM77463.1
AK000531 mRNA Translation: BAA91235.1
AJ276469 mRNA Translation: CAB83042.1
AL021578 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75848.1
CH471077 Genomic DNA Translation: EAW75854.1
AL591565 mRNA Translation: CAC39141.1
BC001105 mRNA Translation: AAH01105.1
BC012818 mRNA Translation: AAH12818.1
BG703352 mRNA No translation available.
CCDSiCCDS42880.1 [Q9BQY9-2]
CCDS42881.1 [Q9BQY9-3]
CCDS56193.1 [Q9BQY9-1]
CCDS56194.1 [Q9BQY9-2]
RefSeqiNP_001041686.1, NM_001048221.2 [Q9BQY9-2]
NP_001041687.1, NM_001048222.2 [Q9BQY9-3]
NP_001041688.1, NM_001048223.2 [Q9BQY9-2]
NP_001041689.1, NM_001048224.2 [Q9BQY9-3]
NP_001041690.2, NM_001048225.2 [Q9BQY9-2]
NP_001184068.1, NM_001197139.1 [Q9BQY9-2]
NP_001184069.1, NM_001197140.1 [Q9BQY9-2]
NP_060948.3, NM_018478.3 [Q9BQY9-1]

3D structure databases

SMRiQ9BQY9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120963, 7 interactors
IntActiQ9BQY9, 4 interactors
MINTiQ9BQY9
STRINGi9606.ENSP00000361795

PTM databases

iPTMnetiQ9BQY9
PhosphoSitePlusiQ9BQY9

Polymorphism and mutation databases

BioMutaiDBNDD2
DMDMi327478587

Proteomic databases

MassIVEiQ9BQY9
PaxDbiQ9BQY9
PeptideAtlasiQ9BQY9
PRIDEiQ9BQY9
ProteomicsDBi63697
78730 [Q9BQY9-1]
78731 [Q9BQY9-2]
78732 [Q9BQY9-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
51972, 49 antibodies

The DNASU plasmid repository

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DNASUi
55861

Genome annotation databases

EnsembliENST00000357275; ENSP00000349822; ENSG00000244274 [Q9BQY9-2]
ENST00000360981; ENSP00000354250; ENSG00000244274 [Q9BQY9-2]
ENST00000372710; ENSP00000361795; ENSG00000244274 [Q9BQY9-4]
ENST00000372712; ENSP00000361797; ENSG00000244274 [Q9BQY9-2]
ENST00000372717; ENSP00000361802; ENSG00000244274 [Q9BQY9-3]
ENST00000372720; ENSP00000361805; ENSG00000244274 [Q9BQY9-1]
ENST00000372722; ENSP00000361807; ENSG00000244274 [Q9BQY9-3]
ENST00000372723; ENSP00000361808; ENSG00000244274 [Q9BQY9-2]
GeneIDi55861
KEGGihsa:55861
UCSCiuc002xnz.4, human [Q9BQY9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55861
DisGeNETi55861
EuPathDBiHostDB:ENSG00000244274.7

GeneCards: human genes, protein and diseases

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GeneCardsi
DBNDD2
HGNCiHGNC:15881, DBNDD2
HPAiENSG00000244274, Tissue enhanced (brain, skeletal muscle)
MIMi611453, gene
neXtProtiNX_Q9BQY9
OpenTargetsiENSG00000244274
PharmGKBiPA25749

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502RZ1K, Eukaryota
GeneTreeiENSGT00940000161212
HOGENOMiCLU_097594_1_0_1
InParanoidiQ9BQY9
OMAiLEQMDMM
OrthoDBi862376at2759
PhylomeDBiQ9BQY9
TreeFamiTF332997

Enzyme and pathway databases

PathwayCommonsiQ9BQY9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
55861, 4 hits in 872 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
DBNDD2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55861
PharosiQ9BQY9, Tdark

Protein Ontology

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PROi
PR:Q9BQY9
RNActiQ9BQY9, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000244274, Expressed in C1 segment of cervical spinal cord and 115 other tissues
ExpressionAtlasiQ9BQY9, baseline and differential
GenevisibleiQ9BQY9, HS

Family and domain databases

InterProiView protein in InterPro
IPR007531, Dysbindin
PANTHERiPTHR16294, PTHR16294, 1 hit
PfamiView protein in Pfam
PF04440, Dysbindin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDBND2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BQY9
Secondary accession number(s): Q331S6
, Q5QPV4, Q5QPV6, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: April 5, 2011
Last modified: August 12, 2020
This is version 156 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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