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UniProtKB - Q9BQY4 (RHXF2_HUMAN)

Entry version 166 (07 Apr 2021)
Sequence version 1 (01 Jun 2001)
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Protein

Rhox homeobox family member 2

Gene

RHOXF2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis.1 Publication

Caution

RHOF2 and RHOF2B are arranged in a head-to-head orientation and share high sequence similarity (>99%). They cannot easily be distinguished and are usually analyzed as a single gene.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi134 – 193HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BQY4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Rhox homeobox family member 2
Alternative name(s):
Paired-like homeobox protein PEPP-2
Testis homeobox gene 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RHOXF2Imported
Synonyms:PEPP2, THG1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:30011, RHOXF2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300447, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BQY4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000131721.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		84528

Open Targets

More...OpenTargetsi		ENSG00000131721

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162401288

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BQY4, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RHOXF2

Domain mapping of disease mutations (DMDM)

More...DMDMi		37537987

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000492461 – 288Rhox homeobox family member 2Add BLAST288

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BQY4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BQY4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BQY4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BQY4

PeptideAtlas

More...PeptideAtlasi		Q9BQY4

PRoteomics IDEntifications database

More...PRIDEi		Q9BQY4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78727

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BQY4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BQY4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis. Not detected in epididymis nor placenta. In testis, mainly expressed in germ cells, but also detected in somatic cells such as Sertoli cells, Leydig cells and peritubular cells (PubMed:28171660).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Predominantly expressed in early stage germ cells, type-B spermatogonia and early spermatocytes.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000131721, Expressed in testis and 34 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BQY4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000131721, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9BQY4
With#Exp.IntAct
ARSA [P15289]3EBI-372094,EBI-2117357
ATXN1 [P54253]4EBI-372094,EBI-930964
BATF3 [Q9NR55]3EBI-372094,EBI-10312707
BOLL - isoform 4 [Q8N9W6-4]3EBI-372094,EBI-11983447
C1orf94 [Q6P1W5]3EBI-372094,EBI-946029
CAMK2A [Q9UQM7]3EBI-372094,EBI-1383687
CEACAM6 [P40199]3EBI-372094,EBI-4314501
CERCAM [Q5T4B2]3EBI-372094,EBI-12261896
CHAC1 [Q9BUX1]2EBI-372094,EBI-751127
CREM - isoform 22 [Q03060-25]3EBI-372094,EBI-12884642
CRX [O43186]3EBI-372094,EBI-748171
CRYBA1 [P05813]3EBI-372094,EBI-7043337
DAB1 [O75553]3EBI-372094,EBI-7875264
DAZAP2 [Q15038]12EBI-372094,EBI-724310
EFEMP2 [O95967]2EBI-372094,EBI-743414
FAM166A [Q6J272]3EBI-372094,EBI-12811067
FAM168A - isoform 2 [Q92567-2]6EBI-372094,EBI-11978259
FAM168B - isoform 2 [A1KXE4-2]3EBI-372094,EBI-12193763
hCG_2003792 [A0A024R5S0]3EBI-372094,EBI-10188461
HNRNPLL [Q8WVV9]3EBI-372094,EBI-535849
KHDC4 - isoform 4 [Q7Z7F0-4]3EBI-372094,EBI-9089060
KLHDC7B [Q96G42]3EBI-372094,EBI-9478422
KRTAP12-2 [P59991]3EBI-372094,EBI-10176379
KRTAP13-2 [Q52LG2]3EBI-372094,EBI-11953846
KRTAP13-4 [Q3LI77]3EBI-372094,EBI-11953996
KRTAP15-1 [Q3LI76]3EBI-372094,EBI-11992140
KRTAP19-5 [Q3LI72]6EBI-372094,EBI-1048945
KRTAP19-6 [Q3LI70]3EBI-372094,EBI-12805508
KRTAP19-7 [Q3SYF9]6EBI-372094,EBI-10241353
KRTAP26-1 [Q6PEX3]3EBI-372094,EBI-3957672
KRTAP6-1 [Q3LI64]5EBI-372094,EBI-12111050
KRTAP6-2 [Q3LI66]3EBI-372094,EBI-11962084
KRTAP7-1 [Q8IUC3]3EBI-372094,EBI-18394498
LASP1 [Q14847]3EBI-372094,EBI-742828
LASP1 - isoform 2 [Q14847-2]3EBI-372094,EBI-9088686
MAGED1 [Q9Y5V3]6EBI-372094,EBI-716006
MDFI [Q99750]3EBI-372094,EBI-724076
MSX2 [P35548]3EBI-372094,EBI-6447480
NKX3-1 [Q99801]3EBI-372094,EBI-1385894
PLOD3 [O60568]2EBI-372094,EBI-741582
PRR20D [P86480]3EBI-372094,EBI-12754095
PRR34 [Q9NV39]3EBI-372094,EBI-11959565
RBFOX2 - isoform 10 [O43251-10]3EBI-372094,EBI-11963050
RBPMS [Q93062]6EBI-372094,EBI-740322
RBPMS - isoform C [Q93062-3]3EBI-372094,EBI-740343
RBPMS2 [Q6ZRY4]3EBI-372094,EBI-11987469
RNF4 [P78317]3EBI-372094,EBI-2340927
SUMO1 [P63165]3EBI-372094,EBI-80140
TENT5B [Q96A09]4EBI-372094,EBI-752030
TENT5C [Q5VWP2]3EBI-372094,EBI-741787
TEP1 [Q99973]3EBI-372094,EBI-947859
TLE5 [Q08117]3EBI-372094,EBI-717810
TOLLIP [Q9H0E2]6EBI-372094,EBI-74615
TRIP13 [Q15645]8EBI-372094,EBI-358993
UBAP2 [Q5T6F2]3EBI-372094,EBI-2514383
VAC14 [Q08AM6]6EBI-372094,EBI-2107455
VENTX [O95231]3EBI-372094,EBI-10191303
ZBTB32 [A0A0C4DGF1]11EBI-372094,EBI-10188476
ZNF683 [Q8IZ20]3EBI-372094,EBI-12005952
Q96EJ43EBI-372094,EBI-750454

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124119, 107 interactors

Protein interaction database and analysis system

More...IntActi		Q9BQY4, 86 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000360441

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BQY4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BQY4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi186 – 195Nuclear localization signalBy similarity10

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi245 – 286Pro-richAdd BLAST42

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the paired-like homeobox family. PEPP subfamily.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0490, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164624

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_044595_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BQY4

Identification of Orthologs from Complete Genome Data

More...OMAi		LCFSMSP

Database of Orthologous Groups

More...OrthoDBi		1514681at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BQY4

TreeFam database of animal gene trees

More...TreeFami		TF339348

Family and domain databases

Conserved Domains Database

More...CDDi		cd00086, homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009057, Homeobox-like_sf
IPR017970, Homeobox_CS
IPR001356, Homeobox_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00046, Homeodomain, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00389, HOX, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00027, HOMEOBOX_1, 1 hit
PS50071, HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9BQY4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPPDQCSQY MTSLLSPAVD DEKELQDMNA MVLSLTEEVK EEEEDAQPEP 
        60         70         80         90        100
EQGTAAGEKL KSAGAQGGEE KDGGGEEKDG GGAGVPGHLW EGDLEGTSGS 
       110        120        130        140        150
DGNVEDSDQS EKEPGQQYSR PQGAVGGLEP GNAQQPNVHA FTPLQLQELE 
       160        170        180        190        200
RIFQREQFPS EFLRRRLARS MNVTELAVQI WFENRRAKWR RHQRALMARN 
       210        220        230        240        250
MLPFMAVGQP VMVTAAEAIT APLFISGMRD DYFWDHSHSS SLCFPMPPFP 
       260        270        280 
PPSLPLPLML LPPMPPAGQA EFGPFPFVIV PSFTFPNV
Length:288
Mass (Da):31,692
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B0E007064515808
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07829768G → R Found in infertile men; unknown pathological significance; decreased induction of target genes expression. 1 PublicationCorresponds to variant dbSNP:rs148604152Ensembl.1
Natural variantiVAR_078298176L → F Found in infertile men; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs199871532Ensembl.1
Natural variantiVAR_078299227G → R Found in infertile men; unknown pathological significance; decreased induction of target genes expression. 1 PublicationCorresponds to variant dbSNP:rs1210761967Ensembl.1
Natural variantiVAR_078300235D → G Found in infertile men; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs6646602Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF317219 mRNA Translation: AAL02160.1
AL590526 mRNA Translation: CAC36519.1
AK058125 mRNA Translation: BAB71675.1
BC021719 mRNA Translation: AAH21719.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14594.1

NCBI Reference Sequences

More...RefSeqi		NP_115887.1, NM_032498.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000371388; ENSP00000360441; ENSG00000131721

Database of genes from NCBI RefSeq genomes

More...GeneIDi		84528

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:84528

UCSC genome browser

More...UCSCi		uc004esl.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF317219 mRNA Translation: AAL02160.1
AL590526 mRNA Translation: CAC36519.1
AK058125 mRNA Translation: BAB71675.1
BC021719 mRNA Translation: AAH21719.1
CCDSiCCDS14594.1
RefSeqiNP_115887.1, NM_032498.2

3D structure databases

SMRiQ9BQY4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124119, 107 interactors
IntActiQ9BQY4, 86 interactors
STRINGi9606.ENSP00000360441

PTM databases

iPTMnetiQ9BQY4
PhosphoSitePlusiQ9BQY4

Genetic variation databases

BioMutaiRHOXF2
DMDMi37537987

Proteomic databases

EPDiQ9BQY4
MassIVEiQ9BQY4
MaxQBiQ9BQY4
PaxDbiQ9BQY4
PeptideAtlasiQ9BQY4
PRIDEiQ9BQY4
ProteomicsDBi78727

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		520, 160 antibodies

The DNASU plasmid repository

More...DNASUi		84528

Genome annotation databases

EnsembliENST00000371388; ENSP00000360441; ENSG00000131721
GeneIDi84528
KEGGihsa:84528
UCSCiuc004esl.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		84528
DisGeNETi84528

GeneCards: human genes, protein and diseases

More...GeneCardsi		RHOXF2
HGNCiHGNC:30011, RHOXF2
HPAiENSG00000131721, Tissue enriched (testis)
MIMi300447, gene
neXtProtiNX_Q9BQY4
OpenTargetsiENSG00000131721
PharmGKBiPA162401288
VEuPathDBiHostDB:ENSG00000131721.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0490, Eukaryota
GeneTreeiENSGT00940000164624
HOGENOMiCLU_044595_1_0_1
InParanoidiQ9BQY4
OMAiLCFSMSP
OrthoDBi1514681at2759
PhylomeDBiQ9BQY4
TreeFamiTF339348

Enzyme and pathway databases

PathwayCommonsiQ9BQY4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		84528, 8 hits in 528 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		84528
PharosiQ9BQY4, Tbio

Protein Ontology

More...PROi		PR:Q9BQY4
RNActiQ9BQY4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000131721, Expressed in testis and 34 other tissues
GenevisibleiQ9BQY4, HS

Family and domain databases

CDDicd00086, homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057, Homeobox-like_sf
IPR017970, Homeobox_CS
IPR001356, Homeobox_dom
PfamiView protein in Pfam
PF00046, Homeodomain, 1 hit
SMARTiView protein in SMART
SM00389, HOX, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027, HOMEOBOX_1, 1 hit
PS50071, HOMEOBOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRHXF2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BQY4
Secondary accession number(s): Q9BR00
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: June 1, 2001
Last modified: April 7, 2021
This is version 166 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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