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Protein

Rhox homeobox family member 2

Gene

RHOXF2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis.1 Publication

Caution

RHOF2 and RHOF2B are arranged in a head-to-head orientation and share high sequence similarity (>99%). They cannot easily be distinguished and are usually analyzed as a single gene.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi134 – 193HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • positive regulation of gene expression Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Rhox homeobox family member 2
Alternative name(s):
Paired-like homeobox protein PEPP-2
Testis homeobox gene 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RHOXF2Imported
Synonyms:PEPP2, THG1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000131721.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30011 RHOXF2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300447 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BQY4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84528

Open Targets

More...
OpenTargetsi
ENSG00000131721

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162401288

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RHOXF2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
37537987

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000492461 – 288Rhox homeobox family member 2Add BLAST288

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BQY4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BQY4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BQY4

PeptideAtlas

More...
PeptideAtlasi
Q9BQY4

PRoteomics IDEntifications database

More...
PRIDEi
Q9BQY4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
78727

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BQY4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BQY4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis. Not detected in epididymis nor placenta. In testis, mainly expressed in germ cells, but also detected in somatic cells such as Sertoli cells, Leydig cells and peritubular cells (PubMed:28171660).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Predominantly expressed in early stage germ cells, type-B spermatogonia and early spermatocytes.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000131721 Expressed in 29 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_RHOXF2

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BQY4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB020794
HPA003314

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
itself4EBI-372094,EBI-372094
Q96EJ44EBI-372094,EBI-750454
AESQ081173EBI-372094,EBI-717810
AESQ08117-24EBI-372094,EBI-11741437
ARID5AQ039896EBI-372094,EBI-948603
ARSAP152894EBI-372094,EBI-2117357
ATXN1P542534EBI-372094,EBI-930964
BAALC-AS2P0C8534EBI-372094,EBI-12828107
BATF3Q9NR554EBI-372094,EBI-10312707
C1orf94Q6P1W54EBI-372094,EBI-946029
CAMK2AQ9UQM74EBI-372094,EBI-1383687
CEACAM6P401994EBI-372094,EBI-4314501
CELF5Q8N6W04EBI-372094,EBI-12139335
CHAC1Q9BUX12EBI-372094,EBI-751127
CRYBA1P058135EBI-372094,EBI-7043337
DAB1O755533EBI-372094,EBI-7875264
DAZAP2Q1503812EBI-372094,EBI-724310
DTX2Q86UW93EBI-372094,EBI-740376
EFEMP2O959674EBI-372094,EBI-743414
FAM168AQ92567-28EBI-372094,EBI-11978259
FAM171A2Q8N0U16EBI-372094,EBI-10264767
hCG_2003792A0A024R5S04EBI-372094,EBI-10188461
HNRNPLLQ8WVV93EBI-372094,EBI-535849
KHDC4Q7Z7F0-44EBI-372094,EBI-9089060
KRTAP19-5Q3LI729EBI-372094,EBI-1048945
KRTAP19-7Q3SYF99EBI-372094,EBI-10241353
KRTAP6-1Q3LI644EBI-372094,EBI-12111050
KRTAP6-2Q3LI664EBI-372094,EBI-11962084
KRTAP7-1Q8IUC34EBI-372094,EBI-18394498
KRTAP8-1Q8IUC24EBI-372094,EBI-10261141
LASP1Q148473EBI-372094,EBI-742828
LASP1Q14847-24EBI-372094,EBI-9088686
LENG8Q96PV63EBI-372094,EBI-739546
MAGED1Q9Y5V39EBI-372094,EBI-716006
PITX1P783373EBI-372094,EBI-748265
PLOD3O605682EBI-372094,EBI-741582
PRR20DP864804EBI-372094,EBI-12754095
PRR34Q9NV394EBI-372094,EBI-11959565
RAMMETQ9BTL33EBI-372094,EBI-744023
RBFOX2O43251-104EBI-372094,EBI-11963050
RBPMSQ930626EBI-372094,EBI-740322
RBPMSQ93062-34EBI-372094,EBI-740343
RBPMS2Q6ZRY44EBI-372094,EBI-11987469
RNF4P783174EBI-372094,EBI-2340927
SUMO1P631653EBI-372094,EBI-80140
TENT5BQ96A095EBI-372094,EBI-752030
TENT5CQ5VWP23EBI-372094,EBI-741787
TENT5DQ8NEK83EBI-372094,EBI-744726
TMCC2O75069-43EBI-372094,EBI-10177480
TOLLIPQ9H0E26EBI-372094,EBI-74615
TRIP13Q156457EBI-372094,EBI-358993
UBAP2Q5T6F24EBI-372094,EBI-2514383
UBE2DNLQ8IWF73EBI-372094,EBI-2340154
VAC14Q08AM67EBI-372094,EBI-2107455
VENTXO952314EBI-372094,EBI-10191303
ZBTB32A0A0C4DGF110EBI-372094,EBI-10188476

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124119, 63 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BQY4, 137 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000360441

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9BQY4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BQY4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi186 – 195Nuclear localization signalBy similarity10

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi245 – 286Pro-richAdd BLAST42

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0490 Eukaryota
ENOG410YIJ3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164624

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154119

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG094802

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BQY4

Identification of Orthologs from Complete Genome Data

More...
OMAi
LMARNMP

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0JEY

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BQY4

TreeFam database of animal gene trees

More...
TreeFami
TF339348

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086 homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00046 Homeodomain, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00389 HOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9BQY4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPPDQCSQY MTSLLSPAVD DEKELQDMNA MVLSLTEEVK EEEEDAQPEP
60 70 80 90 100
EQGTAAGEKL KSAGAQGGEE KDGGGEEKDG GGAGVPGHLW EGDLEGTSGS
110 120 130 140 150
DGNVEDSDQS EKEPGQQYSR PQGAVGGLEP GNAQQPNVHA FTPLQLQELE
160 170 180 190 200
RIFQREQFPS EFLRRRLARS MNVTELAVQI WFENRRAKWR RHQRALMARN
210 220 230 240 250
MLPFMAVGQP VMVTAAEAIT APLFISGMRD DYFWDHSHSS SLCFPMPPFP
260 270 280
PPSLPLPLML LPPMPPAGQA EFGPFPFVIV PSFTFPNV
Length:288
Mass (Da):31,692
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B0E007064515808
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07829768G → R Found in infertile men; unknown pathological significance; decreased induction of target genes expression. 1 PublicationCorresponds to variant dbSNP:rs148604152Ensembl.1
Natural variantiVAR_078298176L → F Found in infertile men; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs199871532Ensembl.1
Natural variantiVAR_078299227G → R Found in infertile men; unknown pathological significance; decreased induction of target genes expression. 1 PublicationCorresponds to variant dbSNP:rs1210761967Ensembl.1
Natural variantiVAR_078300235D → G Found in infertile men; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs6646602Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF317219 mRNA Translation: AAL02160.1
AL590526 mRNA Translation: CAC36519.1
AK058125 mRNA Translation: BAB71675.1
BC021719 mRNA Translation: AAH21719.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14594.1

NCBI Reference Sequences

More...
RefSeqi
NP_115887.1, NM_032498.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.567620

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000371388; ENSP00000360441; ENSG00000131721

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84528

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84528

UCSC genome browser

More...
UCSCi
uc004esl.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF317219 mRNA Translation: AAL02160.1
AL590526 mRNA Translation: CAC36519.1
AK058125 mRNA Translation: BAB71675.1
BC021719 mRNA Translation: AAH21719.1
CCDSiCCDS14594.1
RefSeqiNP_115887.1, NM_032498.2
UniGeneiHs.567620

3D structure databases

ProteinModelPortaliQ9BQY4
SMRiQ9BQY4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124119, 63 interactors
IntActiQ9BQY4, 137 interactors
STRINGi9606.ENSP00000360441

PTM databases

iPTMnetiQ9BQY4
PhosphoSitePlusiQ9BQY4

Polymorphism and mutation databases

BioMutaiRHOXF2
DMDMi37537987

Proteomic databases

EPDiQ9BQY4
MaxQBiQ9BQY4
PaxDbiQ9BQY4
PeptideAtlasiQ9BQY4
PRIDEiQ9BQY4
ProteomicsDBi78727

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
84528
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371388; ENSP00000360441; ENSG00000131721
GeneIDi84528
KEGGihsa:84528
UCSCiuc004esl.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84528
DisGeNETi84528
EuPathDBiHostDB:ENSG00000131721.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RHOXF2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0056374
HGNCiHGNC:30011 RHOXF2
HPAiCAB020794
HPA003314
MIMi300447 gene
neXtProtiNX_Q9BQY4
OpenTargetsiENSG00000131721
PharmGKBiPA162401288

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
GeneTreeiENSGT00940000164624
HOGENOMiHOG000154119
HOVERGENiHBG094802
InParanoidiQ9BQY4
OMAiLMARNMP
OrthoDBiEOG091G0JEY
PhylomeDBiQ9BQY4
TreeFamiTF339348

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84528

Protein Ontology

More...
PROi
PR:Q9BQY4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000131721 Expressed in 29 organ(s), highest expression level in testis
CleanExiHS_RHOXF2
GenevisibleiQ9BQY4 HS

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
PfamiView protein in Pfam
PF00046 Homeodomain, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRHXF2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BQY4
Secondary accession number(s): Q9BR00
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: June 1, 2001
Last modified: December 5, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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