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Protein

Condensin complex subunit 3

Gene

NCAPG

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.1 Publication

Miscellaneous

Overexpressed in some cancer lines and some tumor cells.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cell division Source: UniProtKB-KW
  • mitotic chromosome condensation Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA condensation, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-2514853 Condensation of Prometaphase Chromosomes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Condensin complex subunit 3
Alternative name(s):
Chromosome-associated protein G
Condensin subunit CAP-G
Short name:
hCAP-G
Melanoma antigen NY-MEL-3
Non-SMC condensin I complex subunit G
XCAP-G homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NCAPG
Synonyms:CAPG, NYMEL3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000109805.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24304 NCAPG

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606280 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BPX3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
64151

Open Targets

More...
OpenTargetsi
ENSG00000109805

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162397165

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NCAPG

Domain mapping of disease mutations (DMDM)

More...
DMDMi
30172941

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000950411 – 1015Condensin complex subunit 3Add BLAST1015

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei390PhosphoserineCombined sources1
Modified residuei674PhosphoserineCombined sources1
Modified residuei931PhosphothreonineCombined sources1
Modified residuei973PhosphoserineCombined sources1
Modified residuei975PhosphoserineCombined sources1
Modified residuei1002PhosphoserineCombined sources1
Modified residuei1015PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPH subunits, activates the condensin complex and is required for chromosome condensation (By similarity).By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BPX3

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9BPX3

MaxQB - The MaxQuant DataBase

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MaxQBi
Q9BPX3

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9BPX3

PeptideAtlas

More...
PeptideAtlasi
Q9BPX3

PRoteomics IDEntifications database

More...
PRIDEi
Q9BPX3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
78586

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BPX3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BPX3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000109805 Expressed in 186 organ(s), highest expression level in amniotic fluid

CleanEx database of gene expression profiles

More...
CleanExi
HS_CAPG
HS_NCAPG

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BPX3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BPX3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039613

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG.1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
NCAPHQ150037EBI-970214,EBI-1046410

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122089, 63 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-979 Condensin I complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9BPX3

Database of interacting proteins

More...
DIPi
DIP-34891N

Protein interaction database and analysis system

More...
IntActi
Q9BPX3, 12 interactors

Molecular INTeraction database

More...
MINTi
Q9BPX3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000251496

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9BPX3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BPX3

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati94 – 131HEAT 1Add BLAST38
Repeati138 – 173HEAT 2Add BLAST36
Repeati174 – 212HEAT 3Add BLAST39
Repeati238 – 275HEAT 4Add BLAST38
Repeati276 – 313HEAT 5Add BLAST38
Repeati399 – 436HEAT 6Add BLAST38
Repeati439 – 478HEAT 7Add BLAST40
Repeati617 – 654HEAT 8Add BLAST38
Repeati687 – 724HEAT 9Add BLAST38
Repeati865 – 907HEAT 10Add BLAST43

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi88 – 91Poly-Glu4
Compositional biasi912 – 917Poly-Thr6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CND3 (condensin subunit 3) family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2025 Eukaryota
COG5218 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001577

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG039407

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BPX3

KEGG Orthology (KO)

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KOi
K06678

Identification of Orthologs from Complete Genome Data

More...
OMAi
LYWRALC

Database of Orthologous Groups

More...
OrthoDBi
108186at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BPX3

TreeFam database of animal gene trees

More...
TreeFami
TF101160

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C

The PANTHER Classification System

More...
PANTHERi
PTHR14418 PTHR14418, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12719 Cnd3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9BPX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGAERRLLSI KEAFRLAQQP HQNQAKLVVA LSRTYRTMDD KTVFHEEFIH
60 70 80 90 100
YLKYVMVVYK REPAVERVIE FAAKFVTSFH QSDMEDDEEE EDGGLLNYLF
110 120 130 140 150
TFLLKSHEAN SNAVRFRVCL LINKLLGSMP ENAQIDDDVF DKINKAMLIR
160 170 180 190 200
LKDKIPNVRI QAVLALSRLQ DPKDDECPVV NAYATLIEND SNPEVRRAVL
210 220 230 240 250
SCIAPSAKTL PKIVGRTKDV KEAVRKLAYQ VLAEKVHMRA MSIAQRVMLL
260 270 280 290 300
QQGLNDRSDA VKQAMQKHLL QGWLRFSEGN ILELLHRLDV ENSSEVAVSV
310 320 330 340 350
LNALFSITPL SELVGLCKNN DGRKLIPVET LTPEIALYWC ALCEYLKSKG
360 370 380 390 400
DEGEEFLEQI LPEPVVYADY LLSYIQSIPV VNEEHRGDFS YIGNLMTKEF
410 420 430 440 450
IGQQLILIIK SLDTSEEGGR KKLLAVLQEI LILPTIPISL VSFLVERLLH
460 470 480 490 500
IIIDDNKRTQ IVTEIISEIR APIVTVGVNN DPADVRKKEL KMAEIKVKLI
510 520 530 540 550
EAKEALENCI TLQDFNRASE LKEEIKALED ARINLLKETE QLEIKEVHIE
560 570 580 590 600
KNDAETLQKC LILCYELLKQ MSISTGLSAT MNGIIESLIL PGIISIHPVV
610 620 630 640 650
RNLAVLCLGC CGLQNQDFAR KHFVLLLQVL QIDDVTIKIS ALKAIFDQLM
660 670 680 690 700
TFGIEPFKTK KIKTLHCEGT EINSDDEQES KEVEETATAK NVLKLLSDFL
710 720 730 740 750
DSEVSELRTG AAEGLAKLMF SGLLVSSRIL SRLILLWYNP VTEEDVQLRH
760 770 780 790 800
CLGVFFPVFA YASRTNQECF EEAFLPTLQT LANAPASSPL AEIDITNVAE
810 820 830 840 850
LLVDLTRPSG LNPQAKTSQD YQALTVHDNL AMKICNEILT SPCSPEIRVY
860 870 880 890 900
TKALSSLELS SHLAKDLLVL LNEILEQVKD RTCLRALEKI KIQLEKGNKE
910 920 930 940 950
FGDQAEAAQD ATLTTTTFQN EDEKNKEVYM TPLRGVKATQ ASKSTQLKTN
960 970 980 990 1000
RGQRKVTVSA RTNRRCQTAE ADSESDHEVP EPESEMKMRL PRRAKTAALE
1010
KSKLNLAQFL NEDLS
Length:1,015
Mass (Da):114,334
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD9ACC205C48F3AF5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y9Z8H0Y9Z8_HUMAN
Condensin complex subunit 3
NCAPG
269Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RA93D6RA93_HUMAN
Condensin complex subunit 3
NCAPG
232Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH00827 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB14429 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB55165 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115R → G in BAB14069 (PubMed:14702039).Curated1
Sequence conflicti276F → V in AAG30732 (PubMed:10910072).Curated1
Sequence conflicti519S → P in BAB55165 (PubMed:14702039).Curated1
Sequence conflicti676D → V in BAB14069 (PubMed:14702039).Curated1
Sequence conflicti681K → R in BAB14069 (PubMed:14702039).Curated1
Sequence conflicti704V → A in BAB14069 (PubMed:14702039).Curated1
Sequence conflicti836N → D in BAB55165 (PubMed:14702039).Curated1
Sequence conflicti1010L → F in AAG30732 (PubMed:10910072).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05304164A → P. Corresponds to variant dbSNP:rs35722563Ensembl.1
Natural variantiVAR_036125265M → T in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_053042581M → I1 PublicationCorresponds to variant dbSNP:rs3795243Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF235023 mRNA Translation: AAG30732.1
AF331796 mRNA Translation: AAG49627.1
AB013299 mRNA Translation: BAB21557.1
AK022512 mRNA Translation: BAB14069.1
AK023147 mRNA Translation: BAB14429.1 Different initiation.
AK027511 mRNA Translation: BAB55165.1 Different initiation.
BC000827 mRNA Translation: AAH00827.1 Different initiation.
BC101476 mRNA Translation: AAI01477.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3424.1

NCBI Reference Sequences

More...
RefSeqi
NP_071741.2, NM_022346.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.567567

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000251496; ENSP00000251496; ENSG00000109805

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64151

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:64151

UCSC genome browser

More...
UCSCi
uc003gpp.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF235023 mRNA Translation: AAG30732.1
AF331796 mRNA Translation: AAG49627.1
AB013299 mRNA Translation: BAB21557.1
AK022512 mRNA Translation: BAB14069.1
AK023147 mRNA Translation: BAB14429.1 Different initiation.
AK027511 mRNA Translation: BAB55165.1 Different initiation.
BC000827 mRNA Translation: AAH00827.1 Different initiation.
BC101476 mRNA Translation: AAI01477.1
CCDSiCCDS3424.1
RefSeqiNP_071741.2, NM_022346.4
UniGeneiHs.567567

3D structure databases

ProteinModelPortaliQ9BPX3
SMRiQ9BPX3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122089, 63 interactors
ComplexPortaliCPX-979 Condensin I complex
CORUMiQ9BPX3
DIPiDIP-34891N
IntActiQ9BPX3, 12 interactors
MINTiQ9BPX3
STRINGi9606.ENSP00000251496

PTM databases

iPTMnetiQ9BPX3
PhosphoSitePlusiQ9BPX3

Polymorphism and mutation databases

BioMutaiNCAPG
DMDMi30172941

Proteomic databases

EPDiQ9BPX3
jPOSTiQ9BPX3
MaxQBiQ9BPX3
PaxDbiQ9BPX3
PeptideAtlasiQ9BPX3
PRIDEiQ9BPX3
ProteomicsDBi78586

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000251496; ENSP00000251496; ENSG00000109805
GeneIDi64151
KEGGihsa:64151
UCSCiuc003gpp.5 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
64151
DisGeNETi64151
EuPathDBiHostDB:ENSG00000109805.9

GeneCards: human genes, protein and diseases

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GeneCardsi
NCAPG
HGNCiHGNC:24304 NCAPG
HPAiHPA039613
MIMi606280 gene
neXtProtiNX_Q9BPX3
OpenTargetsiENSG00000109805
PharmGKBiPA162397165

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2025 Eukaryota
COG5218 LUCA
GeneTreeiENSGT00390000001577
HOVERGENiHBG039407
InParanoidiQ9BPX3
KOiK06678
OMAiLYWRALC
OrthoDBi108186at2759
PhylomeDBiQ9BPX3
TreeFamiTF101160

Enzyme and pathway databases

ReactomeiR-HSA-2514853 Condensation of Prometaphase Chromosomes

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NCAPG human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
NCAPG

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
64151

Protein Ontology

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PROi
PR:Q9BPX3

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000109805 Expressed in 186 organ(s), highest expression level in amniotic fluid
CleanExiHS_CAPG
HS_NCAPG
ExpressionAtlasiQ9BPX3 baseline and differential
GenevisibleiQ9BPX3 HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C
PANTHERiPTHR14418 PTHR14418, 1 hit
PfamiView protein in Pfam
PF12719 Cnd3, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCND3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BPX3
Secondary accession number(s): Q3MJE0
, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: June 1, 2001
Last modified: January 16, 2019
This is version 164 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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