UniProtKB - Q9BDN5 (Q9BDN5_CERAT)
Protein
T-cell-specific surface glycoprotein CD28
Gene
N/A
Organism
Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
Status
Functioni
GO - Biological processi
- immune response Source: InterPro
- positive regulation of interleukin-2 production Source: UniProtKB
- positive regulation of mitotic nuclear division Source: UniProtKB
- positive regulation of T cell proliferation Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: T-cell-specific surface glycoprotein CD28ARBA annotation |
Organismi | Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)Imported |
Taxonomic identifieri | 9531 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Cercocebus |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 153 – 178 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5004324643 | 19 – 220 | T-cell-specific surface glycoprotein CD28Sequence analysisAdd BLAST | 202 |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 114 | IGvInterPro annotationAdd BLAST | 80 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 197 – 220 | DisorderedSequence analysisAdd BLAST | 24 |
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationFamily and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR008093, CD28 IPR040216, CTLA4/CD28 IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013106, Ig_V-set |
PANTHERi | PTHR11494, PTHR11494, 1 hit |
Pfami | View protein in Pfam PF15910, V-set_2, 1 hit |
PRINTSi | PR01717, CD28ANTIGEN |
SMARTi | View protein in SMART SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9BDN5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRLLLALNL LPSIRVTGNK ILVKQSPMLV AYDNAVNLSC KYSYNLFSRE
60 70 80 90 100
FRASLHKGLD SAVEVCVVYG NYSQQLQVYP KTGFNCDGKL GNESVTFYLQ
110 120 130 140 150
NLYVNQTDIY FCKIEVMYPP PYLDNEKSNG TIIHVKGKHL CPSPLFPGPS
160 170 180 190 200
KPFWALVVVG GVLACYSLLV TVAFRIFWMR SKRSRLLHSD YMNMTPRRPG
210 220
PTRKHYQPYA PPRDFAAYRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF344842 mRNA Translation: AAK37601.1 |
RefSeqi | NP_001292880.1, NM_001305951.1 |
Genome annotation databases
GeneIDi | 105580070 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF344842 mRNA Translation: AAK37601.1 |
RefSeqi | NP_001292880.1, NM_001305951.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 105580070 |
Organism-specific databases
CTDi | 940 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR008093, CD28 IPR040216, CTLA4/CD28 IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013106, Ig_V-set |
PANTHERi | PTHR11494, PTHR11494, 1 hit |
Pfami | View protein in Pfam PF15910, V-set_2, 1 hit |
PRINTSi | PR01717, CD28ANTIGEN |
SMARTi | View protein in SMART SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9BDN5_CERAT | |
Accessioni | Q9BDN5Primary (citable) accession number: Q9BDN5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | October 7, 2020 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |