Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q9ASS7 (CAAT2_ARATH)

Entry version 133 (25 May 2022)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
Add a publicationFeedback
Protein

Cationic amino acid transporter 2, vacuolar

Gene

CAT2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Permease involved in the transport of the cationic amino acids.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Transport

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.3.3.13, the amino acid-polyamine-organocation (apc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cationic amino acid transporter 2, vacuolar
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CAT2
Ordered Locus Names:At1g58030
ORF Names:T15M6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT1G58030

The Arabidopsis Information Resource

More...TAIRi		locus:2196245, AT1G58030

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 48CytoplasmicSequence analysisAdd BLAST48
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Topological domaini70 – 76VacuolarSequence analysis7
Transmembranei77 – 97HelicalSequence analysisAdd BLAST21
Topological domaini98 – 108CytoplasmicSequence analysisAdd BLAST11
Transmembranei109 – 131HelicalSequence analysisAdd BLAST23
Topological domaini132 – 171VacuolarSequence analysisAdd BLAST40
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Topological domaini193 – 200CytoplasmicSequence analysis8
Transmembranei201 – 221HelicalSequence analysisAdd BLAST21
Topological domaini222 – 235VacuolarSequence analysisAdd BLAST14
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Topological domaini257 – 280CytoplasmicSequence analysisAdd BLAST24
Transmembranei281 – 301HelicalSequence analysisAdd BLAST21
Topological domaini302 – 324VacuolarSequence analysisAdd BLAST23
Transmembranei325 – 345HelicalSequence analysisAdd BLAST21
Topological domaini346 – 376CytoplasmicSequence analysisAdd BLAST31
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398VacuolarSequence analysis1
Transmembranei399 – 419HelicalSequence analysisAdd BLAST21
Topological domaini420 – 493CytoplasmicSequence analysisAdd BLAST74
Transmembranei494 – 514HelicalSequence analysisAdd BLAST21
Topological domaini515 – 524VacuolarSequence analysis10
Transmembranei525 – 545HelicalSequence analysisAdd BLAST21
Topological domaini546 – 560CytoplasmicSequence analysisAdd BLAST15
Transmembranei561 – 581HelicalSequence analysisAdd BLAST21
Topological domaini582 – 585VacuolarSequence analysis4
Transmembranei586 – 606HelicalSequence analysisAdd BLAST21
Topological domaini607 – 635CytoplasmicSequence analysisAdd BLAST29

Keywords - Cellular componenti

Membrane, Vacuole

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004157781 – 635Cationic amino acid transporter 2, vacuolarAdd BLAST635

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9ASS7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		239122

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, stems, flowers, leaves, and siliques.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9ASS7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9ASS7, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		3702.AT1G58030.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9ASS7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9ASS7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1286, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_007946_15_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9ASS7

Identification of Orthologs from Complete Genome Data

More...OMAi		WFAKTHP

Database of Orthologous Groups

More...OrthoDBi		439017at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9ASS7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002293, AA/rel_permease1
IPR029485, CAT_C

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13520, AA_permease_2, 1 hit
PF13906, AA_permease_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ASS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGFLVDTQKE GGGHSWGYVR SLVRRKQVDS ANGQSHGHQL ARALTVPHLV 
        60         70         80         90        100
AIGVGATIGA GVYILVGTVA REHSGPSLAL SFLIAGIAAG LSAFCYAELS 
       110        120        130        140        150
SRCPSAGSAY HYSYICVGEG VAWIIGWALI LEYTIGGSAV ARGISPNLAL 
       160        170        180        190        200
IFGGEDGLPA ILARHQIPGL DIVVDPCAAI LVFVVTGLLC MGIKESTFAQ 
       210        220        230        240        250
GIVTAVNVCV LLFVIVAGSY LGFKTGWPGY ELPTGFFPFG VDGMFAGSAT 
       260        270        280        290        300
VFFAFIGFDS VASTAEEVRN PQRDLPIGIG LALLLCCSLY MMVSIVIVGL 
       310        320        330        340        350
IPYYAMDPDT PISSAFASHD MQWAVYLITL GAVMALCSAL MGALLPQPRI 
       360        370        380        390        400
LMAMARDGLL PSIFSDINKR TQVPVKATVA TGLCAATLAF FMDVSQLAGM 
       410        420        430        440        450
VSVGTLLAFT MVAISVLILR YVPPDEQPLP SSLQERIDSV SFICGETTSS 
       460        470        480        490        500
GHVGTSDSSH QPLIVNNDAL VDVPLIKNQE ALGCLVLSEE TRRIVAGWSI 
       510        520        530        540        550
MFTCVGAFLL SYAASSLSFP GLIRYPLCGV GGCLLLAGLI ALSSIDQDDA 
       560        570        580        590        600
RHTFGHSGGY MCPFVPLLPI ICILINMYLL VNLGSATWAR VSVWLLIGVI 
       610        620        630 
VYVFYGRKNS SLANAVYVTT AHAEEIYREH EGSLA
Length:635
Mass (Da):67,115
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i34F3D17A57DF738E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti391F → I in AAN17434 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC079604 Genomic DNA No translation available.
CP002684 Genomic DNA Translation: AEE33488.1
AF367304 mRNA Translation: AAK32891.1
BT000457 mRNA Translation: AAN17434.1
BT046174 mRNA Translation: ACI49773.1

NCBI Reference Sequences

More...RefSeqi		NP_849822.1, NM_179491.3

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT1G58030.1; AT1G58030.1; AT1G58030

Database of genes from NCBI RefSeq genomes

More...GeneIDi		842170

Gramene; a comparative resource for plants

More...Gramenei		AT1G58030.1; AT1G58030.1; AT1G58030

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT1G58030

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079604 Genomic DNA No translation available.
CP002684 Genomic DNA Translation: AEE33488.1
AF367304 mRNA Translation: AAK32891.1
BT000457 mRNA Translation: AAN17434.1
BT046174 mRNA Translation: ACI49773.1
RefSeqiNP_849822.1, NM_179491.3

3D structure databases

AlphaFoldDBiQ9ASS7
SMRiQ9ASS7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G58030.1

Protein family/group databases

TCDBi2.A.3.3.13, the amino acid-polyamine-organocation (apc) family

Proteomic databases

PaxDbiQ9ASS7
ProteomicsDBi239122

Genome annotation databases

EnsemblPlantsiAT1G58030.1; AT1G58030.1; AT1G58030
GeneIDi842170
GrameneiAT1G58030.1; AT1G58030.1; AT1G58030
KEGGiath:AT1G58030

Organism-specific databases

AraportiAT1G58030
TAIRilocus:2196245, AT1G58030

Phylogenomic databases

eggNOGiKOG1286, Eukaryota
HOGENOMiCLU_007946_15_1_1
InParanoidiQ9ASS7
OMAiWFAKTHP
OrthoDBi439017at2759
PhylomeDBiQ9ASS7

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9ASS7

Gene expression databases

ExpressionAtlasiQ9ASS7, baseline and differential
GenevisibleiQ9ASS7, AT

Family and domain databases

InterProiView protein in InterPro
IPR002293, AA/rel_permease1
IPR029485, CAT_C
PfamiView protein in Pfam
PF13520, AA_permease_2, 1 hit
PF13906, AA_permease_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAAT2_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ASS7
Secondary accession number(s): Q8H182
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: June 1, 2001
Last modified: May 25, 2022
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again