Class E basic helix-loop-helix protein 41

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• bHLH transcription factor binding Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
• DNA-binding transcription factor activity, RNA polymerase II-specific Source: BHF-UCLInferred from direct assayⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • "Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system."
    Hamaguchi H., Fujimoto K., Kawamoto T., Noshiro M., Maemura K., Takeda N., Nagai R., Furukawa M., Honma S., Honma K., Kurihara H., Kato Y.
    Biochem. J. 382:43-50(2004) [PubMed] [Europe PMC] [Abstract]
• DNA-binding transcription repressor activity, RNA polymerase II-specific Source: BHF-UCLInferred from direct assayⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
  • "Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system."
    Hamaguchi H., Fujimoto K., Kawamoto T., Noshiro M., Maemura K., Takeda N., Nagai R., Furukawa M., Honma S., Honma K., Kurihara H., Kato Y.
    Biochem. J. 382:43-50(2004) [PubMed] [Europe PMC] [Abstract]
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• E-box binding Source: BHF-UCLInferred from direct assayⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
  • "Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system."
    Hamaguchi H., Fujimoto K., Kawamoto T., Noshiro M., Maemura K., Takeda N., Nagai R., Furukawa M., Honma S., Honma K., Kurihara H., Kato Y.
    Biochem. J. 382:43-50(2004) [PubMed] [Europe PMC] [Abstract]
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• histone deacetylase binding Source: BHF-UCLInferred from direct assayⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• MRF binding Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• protein heterodimerization activity Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ipi">GO evidence code guide</a></p> Inferred from physical interactionⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • Ref.4

    "Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1."
    Sato F., Kawamoto T., Fujimoto K., Noshiro M., Honda K.K., Honma S., Honma K., Kato Y.
    Eur. J. Biochem. 271:4409-4419(2004) [PubMed] [Europe PMC] [Abstract]

    Cited for: SUBUNIT, HETERODIMERIZATION WITH BHLHE40.
• protein homodimerization activity Source: BHF-UCLInferred from physical interactionⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II activating transcription factor binding Source: BHF-UCLInferred from direct assayⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
  • "Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system."
    Hamaguchi H., Fujimoto K., Kawamoto T., Noshiro M., Maemura K., Takeda N., Nagai R., Furukawa M., Honma S., Honma K., Kurihara H., Kato Y.
    Biochem. J. 382:43-50(2004) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II regulatory region sequence-specific DNA binding Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief. Bioinformatics 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• transcription corepressor activity Source: UniProtKBInferred from direct assayⁱ
  • Ref.6

    "The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors."
    Cho Y., Noshiro M., Choi M., Morita K., Kawamoto T., Fujimoto K., Kato Y., Makishima M.
    Mol. Pharmacol. 76:1360-1369(2009) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INDUCTION.

GO - Biological processⁱ

• anterior/posterior pattern specification Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief. Bioinformatics 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• cell differentiation Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief. Bioinformatics 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• circadian regulation of gene expression Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • Ref.5

    "DEC1 modulates the circadian phase of clock gene expression."
    Nakashima A., Kawamoto T., Honda K.K., Ueshima T., Noshiro M., Iwata T., Fujimoto K., Kubo H., Honma S., Yorioka N., Kohno N., Kato Y.
    Mol. Cell. Biol. 28:4080-4092(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION.
• circadian rhythm Source: UniProtKB <p>Inferred from Expression Pattern</p> <p>Covers cases where the annotation is inferred from the timing or location of expression of a gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iep">GO evidence code guide</a></p> Inferred from expression patternⁱ
  • Ref.6

    "The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors."
    Cho Y., Noshiro M., Choi M., Morita K., Kawamoto T., Fujimoto K., Kato Y., Makishima M.
    Mol. Pharmacol. 76:1360-1369(2009) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INDUCTION.
• negative regulation of myotube differentiation Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
• negative regulation of transcription, DNA-templated Source: UniProtKBInferred from direct assayⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • Ref.8

    "A novel protein, CHRONO, functions as a core component of the mammalian circadian clock."
    Goriki A., Hatanaka F., Myung J., Kim J.K., Yoritaka T., Tanoue S., Abe T., Kiyonari H., Fujimoto K., Kato Y., Todo T., Matsubara A., Forger D., Takumi T.
    PLoS Biol. 12:E1001839-E1001839(2014) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH CIART.
• negative regulation of transcription by competitive promoter binding Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
• negative regulation of transcription by RNA polymerase II Source: BHF-UCLInferred from direct assayⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
• regulation of neurogenesis Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief. Bioinformatics 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityⁱ

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

GO - Molecular functionⁱ

• bHLH transcription factor binding Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
• histone deacetylase binding Source: BHF-UCLInferred from direct assayⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• MRF binding Source: BHF-UCLInferred from direct assayⁱ
  • "mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression."
    Azmi S., Sun H., Ozog A., Taneja R.
    J. Biol. Chem. 278:20098-20109(2003) [PubMed] [Europe PMC] [Abstract]
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• protein heterodimerization activity Source: BHF-UCLInferred from physical interactionⁱ
  • Ref.2

    "Dec1 and Dec2 are regulators of the mammalian molecular clock."
    Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.I.
    Nature 419:841-844(2002) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, INTERACTION WITH ARNTL.
  • Ref.4

    "Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1."
    Sato F., Kawamoto T., Fujimoto K., Noshiro M., Honda K.K., Honma S., Honma K., Kato Y.
    Eur. J. Biochem. 271:4409-4419(2004) [PubMed] [Europe PMC] [Abstract]

    Cited for: SUBUNIT, HETERODIMERIZATION WITH BHLHE40.
• protein homodimerization activity Source: BHF-UCLInferred from physical interactionⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II activating transcription factor binding Source: BHF-UCLInferred from direct assayⁱ
  • "Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements."
    Fujimoto K., Hamaguchi H., Hashiba T., Nakamura T., Kawamoto T., Sato F., Noshiro M., Bhawal U.K., Suardita K., Kato Y.
    Int. J. Mol. Med. 19:925-932(2007) [PubMed] [Europe PMC] [Abstract]

Protein-protein interaction databases

Miscellaneous databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Compositional bias

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MDEGIPHLQE RQLLEHRDFI GLDYSSLYMC KPKRSLKRDD TKDTYKLPHR 
        60         70         80         90        100
LIEKKRRDRI NECIAQLKDL LPEHLKLTTL GHLEKAVVLE LTLKHLKALT 
       110        120        130        140        150
ALTEQQHQKI IALQNGERSL KSPVQADLDA FHSGFQTCAK EVLQYLARFE 
       160        170        180        190        200
SWTPREPRCA QLVSHLHAVA TQLLTPQVPS GRGSGRAPCS AGAAAASGPE 
       210        220        230        240        250
RVARCVPVIQ RTQPGTEPEH DTDTDSGYGG EAEQGRAAVK QEPPGDSSPA 
       260        270        280        290        300
PKRPKLEARG ALLGPEPALL GSLVALGGGA PFAQPAAAPF CLPFYLLSPS 
       310        320        330        340        350
AAAYVQPWLD KSGLDKYLYP AAAAPFPLLY PGIPAAAAAA AAAAFPCLSS 
       360        370        380        390        400
VLSPPPEKAG ATAGAPFLAH EVAPPGPLRP QHAHSRTHLP RAVNPESSQE 
       410
DATQPAKDAP                                             

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. MGD cross-references
   Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot