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Protein
Submitted name:

Microfibril-associated glycoprotein 1

Gene

Mfap2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1566948 Elastic fibre formation
R-MMU-2129379 Molecules associated with elastic fibres

Names & Taxonomyi

Protein namesi
Submitted name:
Microfibril-associated glycoprotein 1Imported
Submitted name:
Microfibrillar-associated protein 2Imported
Gene namesi
Name:Mfap2Imported
Synonyms:Magp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:99559 Mfap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501509961719 – 185Sequence analysisAdd BLAST167

Expressioni

Gene expression databases

BgeeiENSMUSG00000060572 Expressed in 216 organ(s), highest expression level in tracheobronchial tree

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 185ShKTInterPro annotationAdd BLAST31

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFBN Eukaryota
ENOG410YIKT LUCA
GeneTreeiENSGT00390000017736
HOGENOMiHOG000231186
HOVERGENiHBG060871
OMAiHYNDQID
OrthoDBiEOG091G0UQX
TreeFamiTF333418

Family and domain databases

InterProiView protein in InterPro
IPR008673 MAGP
IPR003582 ShKT_dom
PANTHERiPTHR16485 PTHR16485, 1 hit
PfamiView protein in Pfam
PF05507 MAGP, 1 hit
PROSITEiView protein in PROSITE
PS51670 SHKT, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q99PM0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMRAACLFL LFMPGLLAQG QYDLDPLPPF PDHVQYNHYG DQIDNADYYD
60 70 80 90 100
YQEVSPRTPE EQFQSQQQVQ QEVIPAPTPE PAAAGDLETE PTEPGPLDCR
110 120 130 140 150
EEQYPCTRLY SIHKPCKQCL NEVCFYSLRR VYVVNKEICV RTVCAHEELL
160 170 180
RADLCRDKFS KCGVMAVSGL CQSVAASCAR SCGGC
Length:185
Mass (Da):20,781
Last modified:June 1, 2001 - v1
Checksum:i7588C921C8525C79
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P55002MFAP2_MOUSE
Microfibrillar-associated protein 2
Mfap2 Magp, Magp1
183Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645625 Genomic DNA No translation available.
AF268473 Genomic DNA Translation: AAG49554.1
AK160213 mRNA Translation: BAE35693.1
AK164920 mRNA Translation: BAE37967.1
RefSeqiNP_001155271.1, NM_001161799.1
NP_032572.2, NM_008546.3
UniGeneiMm.7386

Genome annotation databases

EnsembliENSMUST00000071977; ENSMUSP00000071868; ENSMUSG00000060572
ENSMUST00000166376; ENSMUSP00000132711; ENSMUSG00000060572
GeneIDi17150
KEGGimmu:17150
UCSCiuc008vnp.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645625 Genomic DNA No translation available.
AF268473 Genomic DNA Translation: AAG49554.1
AK160213 mRNA Translation: BAE35693.1
AK164920 mRNA Translation: BAE37967.1
RefSeqiNP_001155271.1, NM_001161799.1
NP_032572.2, NM_008546.3
UniGeneiMm.7386

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071977; ENSMUSP00000071868; ENSMUSG00000060572
ENSMUST00000166376; ENSMUSP00000132711; ENSMUSG00000060572
GeneIDi17150
KEGGimmu:17150
UCSCiuc008vnp.2 mouse

Organism-specific databases

CTDi4237
MGIiMGI:99559 Mfap2

Phylogenomic databases

eggNOGiENOG410IFBN Eukaryota
ENOG410YIKT LUCA
GeneTreeiENSGT00390000017736
HOGENOMiHOG000231186
HOVERGENiHBG060871
OMAiHYNDQID
OrthoDBiEOG091G0UQX
TreeFamiTF333418

Enzyme and pathway databases

ReactomeiR-MMU-1566948 Elastic fibre formation
R-MMU-2129379 Molecules associated with elastic fibres

Miscellaneous databases

ChiTaRSiMfap2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060572 Expressed in 216 organ(s), highest expression level in tracheobronchial tree

Family and domain databases

InterProiView protein in InterPro
IPR008673 MAGP
IPR003582 ShKT_dom
PANTHERiPTHR16485 PTHR16485, 1 hit
PfamiView protein in Pfam
PF05507 MAGP, 1 hit
PROSITEiView protein in PROSITE
PS51670 SHKT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ99PM0_MOUSE
AccessioniPrimary (citable) accession number: Q99PM0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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