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Entry version 67 (10 Feb 2021)
Sequence version 1 (01 Jun 2001)
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Protein
Submitted name:

Mage-d3

Gene

Tro

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Mage-d3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TroImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1928994, Tro

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q99PB3

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini589 – 787MAGEInterPro annotationAdd BLAST199

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 82DisorderedSequence analysisAdd BLAST82
Regioni100 – 143DisorderedSequence analysisAdd BLAST44
Regioni223 – 510DisorderedSequence analysisAdd BLAST288
Regioni545 – 577DisorderedSequence analysisAdd BLAST33
Regioni977 – 1002DisorderedSequence analysisAdd BLAST26
Regioni1827 – 1850DisorderedSequence analysisAdd BLAST24
Regioni1865 – 1934DisorderedSequence analysisAdd BLAST70
Regioni1955 – 1987DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi237 – 437PolarSequence analysisAdd BLAST201
Compositional biasi455 – 483PolarSequence analysisAdd BLAST29

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1200, 1 hit
1.10.10.1210, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037445, MAGE
IPR041898, MAGE_WH1
IPR041899, MAGE_WH2
IPR002190, MHD_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11736, PTHR11736, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01454, MAGE, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01373, MAGE, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50838, MAGE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q99PB3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRRNDHGHR VPTFQGPLPP AGSLGLPFSP DVQSETTEKD PPIASRSKKN
60 70 80 90 100
KNKKNSIKPM DKTTPAPPPV PSANDNASNK PKVTLQALNL PMFTQISQAS
110 120 130 140 150
ATTEAPNIQA SVTSQTQKAK TMRVTPKVSL TGSEDATTQL KPPLQALNLP
160 170 180 190 200
VTTPTIQTPV ANESANSLAS TAVNKSKKAS TANNAANKTV PSAAEISLAS
210 220 230 240 250
AATHTVTTQG QAAKETGSIQ TIAATARSKK IPKGKRTPAK TTNTDNEYVE
260 270 280 290 300
ASNAIEASSR QIGASGRQTE ASNRQIEASS RQTEASNRQT EASSRQTEAS
310 320 330 340 350
SRQTETSNRQ IGASNRQIMA SNRQIGASNR QIEASNRQIG ASNRQTEVSS
360 370 380 390 400
RQIEASNRQI GASNRQTEAS NRQIGASNRQ TEASNRQIGA SNRQTDASNR
410 420 430 440 450
QTDASNRQTE ASSRQTEASS RQTEASSRQT EASSRQIEAS AAAVRPKKPR
460 470 480 490 500
GKKGTNKGSN SASEPSEAPP AIQTVTNHAL SVTVRIRRGS RARKAANKNR
510 520 530 540 550
ATESQAQIAE QGAQASEASI SALETQVAAA VQALADDYLA QLSLEPTTRT
560 570 580 590 600
RGKRNRKSKH PNGEERTGNN YRRIPWGRRL PPPRDVAILQ ERANKLVKYL
610 620 630 640 650
LVKDQTKIPI KRSDMLKDVI QEYEDYFPEI IERASYALEK MFRVNLKEID
660 670 680 690 700
KQNNLYILIS TQESSAGIMG TSKDTPKLGL LMVILSVIFM NGNKASEAVI
710 720 730 740 750
WEVLRKLGLH PGVKHSLFGE VKKLITDEFV KQKYLEYKRV PNSRPPEYEF
760 770 780 790 800
FWGLRSYHET SKMKVLKFAC KVQKKDPKDW AAQYREAVEM DIQAAAVAVA
810 820 830 840 850
EAKARAEARA QMGIGEEAVA GPWNWDDMDI NCLTREELGD DAQAWCRFSF
860 870 880 890 900
EIEPRAQENA DPTTNVLFNQ GATTRNSFSD GAGISFGGIT NPSGGFGGIS
910 920 930 940 950
NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS
960 970 980 990 1000
NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS NPSGGFGGIS
1010 1020 1030 1040 1050
NPSGGFGGRN SITFGSVPNT SANFSSAPSI SFGDTPNTST SFSGGANSSF
1060 1070 1080 1090 1100
SGTPSTSAPF CNTASISFGG APSTSTSFST ASISFGGAPS TSTSLSTASI
1110 1120 1130 1140 1150
SFGGAPSTST SFSTASISFG GAPSTSTSLS TASISFGGAP SINSSSGGSS
1160 1170 1180 1190 1200
VSFGGAPTTS TSFSGGPCIS FGGAPCTTAS ISGGASSGFG STLCSTNPGF
1210 1220 1230 1240 1250
SALSTNTSFG SAPTTSTVFS GAVSTTTGFG GTLSTSVCFG SSPYSGAGFG
1260 1270 1280 1290 1300
GTLSTSISFG GSPSTNTGFG GTLSTSVSFG ASSSTSSDFG GTLSTSVSFG
1310 1320 1330 1340 1350
GSSGANAGFG GTLNSSTSFG GAISTSTGFG SALNNSANFG GAISTSFSGV
1360 1370 1380 1390 1400
LNSSASFGGA INTSAGFGST LNSSASFGSA LSTSASFGGV LNGRAGFGGA
1410 1420 1430 1440 1450
LNTNATFGGV LNGSAGFGGA MNTNATFGGA LNSNAGFGGA ISTSTNFGGA
1460 1470 1480 1490 1500
LNNSAGFGGA MNTSASFGGV LNNSAGFGGA INTSANFGGA LTNSAGFGGA
1510 1520 1530 1540 1550
ISTSASFGGA LNNSAGFGGA ISTSASFGGA LNNSAGFGGA ISTNASFGGA
1560 1570 1580 1590 1600
ISNSPDFGGA FSTSVGFGGT LNTTDFGSNH SNSISFGSAP TTSVSFGGSH
1610 1620 1630 1640 1650
STNLCFGGAP STSLCFGSAS NTNLCFGGSN STNCFSGATS ANFNEGHSIS
1660 1670 1680 1690 1700
FGNGLSTSAG FGNGLGTSAG FDSSLGTSTG FGGSLGPSAS FNGGLGTSTG
1710 1720 1730 1740 1750
FGGGLGTSTD FSGGLNHNAD FNGGLGNSAG FNGGLNTNTD FGGELGTSAG
1760 1770 1780 1790 1800
FGDGLGSSTS FGAGLVTSDG FAGNLGTNTG FGGTLGTGAG FSVSLNNGNG
1810 1820 1830 1840 1850
FGNGPNASFN RGLNTIIGFG SGSNTSNGFT GEPNTGSSFS NGPSSIVGFS
1860 1870 1880 1890 1900
GGPSTGAGFC SGPSTGGFGG GPSTGPGFGG PSTGPGFGGP STGGGFGGPN
1910 1920 1930 1940 1950
TGGGFGGPST GGGFGGPSTG GGFGGPSTGG GFGGPSTAAG FGSGLSTSTG
1960 1970 1980
FGGGLNTSAG FSGGPPSTGT GFGGGASSHG GCGFPYG
Length:1,987
Mass (Da):197,158
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBFDB3305DF859D01
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF319977 mRNA Translation: AAK01205.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF319977 mRNA Translation: AAK01205.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiQ99PB3

Organism-specific databases

MGIiMGI:1928994, Tro

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tro, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di1.10.10.1200, 1 hit
1.10.10.1210, 1 hit
InterProiView protein in InterPro
IPR037445, MAGE
IPR041898, MAGE_WH1
IPR041899, MAGE_WH2
IPR002190, MHD_dom
PANTHERiPTHR11736, PTHR11736, 2 hits
PfamiView protein in Pfam
PF01454, MAGE, 1 hit
SMARTiView protein in SMART
SM01373, MAGE, 1 hit
PROSITEiView protein in PROSITE
PS50838, MAGE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ99PB3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99PB3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 10, 2021
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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