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Entry version 140 (16 Oct 2019)
Sequence version 2 (27 Jul 2011)
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Protein

Contactin-associated protein-like 4

Gene

Cntnap4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Contactin-associated protein-like 4
Alternative name(s):
Cell recognition molecule Caspr4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cntnap4
Synonyms:Caspr4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2183572 Cntnap4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini28 – 1243ExtracellularSequence analysisAdd BLAST1216
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1244 – 1264HelicalSequence analysisAdd BLAST21
Topological domaini1265 – 1310CytoplasmicSequence analysisAdd BLAST46

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Synaptic defects characterized by increased dopamine but decreased GABA signaling. A reduction in the output of cortical parvalbumin (PV)-positive GABAergic basket cells is observed, together with an increase of midbrain dopaminergic release in the nucleus accumbens. Increased dopaminergic signaling induces behavior abnormalities, characterized by severe and highly penetrant over-grooming behavior, resulting in whisker, face and sometimes body hair loss but rarely lesions. The over-grooming phenotype can be pharmacologically reversed following administration of haloperidol drug.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001951128 – 1310Contactin-associated protein-like 4Add BLAST1283

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi33 ↔ 179By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi262N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi287N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi334 ↔ 366By similarity
Glycosylationi361N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi517 ↔ 549By similarity
Glycosylationi540N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi555 ↔ 566By similarity
Disulfide bondi560 ↔ 575By similarity
Glycosylationi576N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi577 ↔ 587By similarity
Glycosylationi604N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi627N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi639N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi708N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi750N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi933 ↔ 960By similarity
Disulfide bondi964 ↔ 977By similarity
Disulfide bondi971 ↔ 986By similarity
Disulfide bondi988 ↔ 998By similarity
Glycosylationi1019N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1025N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1075N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1169 ↔ 1204By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q99P47

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q99P47

PRoteomics IDEntifications database

More...
PRIDEi
Q99P47

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2232

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q99P47

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q99P47

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specifically present in developing cortical interneurons: highly expressed in cortical parvalbumin (PV) cells and midbrain dopaminergic neurons and is localized presynaptically (at protein level). Also present in the substantia nigra pars compacta (SnC) and ventral tegmental area (VTA) midbrain dopaminergic projection populations.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000031772 Expressed in 102 organ(s), highest expression level in substantia nigra

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q99P47 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q99P47 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TIAM1.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000112511

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q99P47

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini33 – 179F5/8 type CPROSITE-ProRule annotationAdd BLAST147
Domaini214 – 346Laminin G-like 1PROSITE-ProRule annotationAdd BLAST133
Domaini400 – 529Laminin G-like 2PROSITE-ProRule annotationAdd BLAST130
Domaini551 – 588EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini589 – 794Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST206
Domaini795 – 960Laminin G-like 3PROSITE-ProRule annotationAdd BLAST166
Domaini960 – 999EGF-like 2PROSITE-ProRule annotationAdd BLAST40
Domaini1048 – 1204Laminin G-like 4PROSITE-ProRule annotationAdd BLAST157

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the neurexin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3516 Eukaryota
ENOG410XPHG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157674

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q99P47

Database of Orthologous Groups

More...
OrthoDBi
338397at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00057 FA58C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028875 CASPR4
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G

The PANTHER Classification System

More...
PANTHERi
PTHR15036:SF40 PTHR15036:SF40, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50026 EGF_3, 2 hits
PS01285 FA58C_1, 1 hit
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q99P47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMGSVAGAV LKMLLLLSTQ NWNRVEAGNS YDCDEPLVSA LPQASFSSSS
60 70 80 90 100
ELSSSHGPGF ARLNRRDGAG GWSPLVSNKY QWLQIDLGER MEVTSVATQG
110 120 130 140 150
GYGSSNWVTS YLLMFSDSGR NWKQYRQEDS IWGFSGNANA DSVVYYRLQP
160 170 180 190 200
SIKARFLRFI PLEWNPKGRI GMRIEVFGCA YRSVVIDLDG KSSLLYRFDQ
210 220 230 240 250
NSLSPIRDII SLKFKTMESD GILLHRAGPA GDHITLELRR GKLFLLINSG
260 270 280 290 300
DARLTSSSTL INLTLGSLLD DQHWHSVLIQ RLGKQVNFTV DEHRRHFHAQ
310 320 330 340 350
GEFNYLDLDY EISFGGISAP AKSVSLPYKH FHGCLENLFY NGVDVIGLVK
360 370 380 390 400
EHSPQIITMG NASFSCSQPQ SMPLTFLSPR SYLVLPASTK EEAISASFQF
410 420 430 440 450
RTWNKAGLLL FSELQLVSGS LLLLLSDGKL KLTLYQPGKS PSDITAGAGL
460 470 480 490 500
GDGQWHSVSL SAKRNHLSVV VDGHISPASP WLGPEQVNSG GVFYFGGCPD
510 520 530 540 550
KGFGSKCKSP LGGFQGCMRL ISINNKMVDL IAVQQGALGN FSDLQIDSCG
560 570 580 590 600
ISDRCLPNSC EHGGECSQSW STFHCNCTNT GYTGATCHSS VYEQSCEAYK
610 620 630 640 650
HQGNASGFYY IDSDGSGPLQ PFLLYCNMTE TAWTVMQHNG SDLMRVRNTH
660 670 680 690 700
SENAHTGVFE YTASMEQLQA AINRAEHCQQ ELVYYCKKSR LVNQQDGSPR
710 720 730 740 750
SWWVGRTNET QTYWGGSLPV HQKCTCGLEG NCIDAQYHCN CDADLNEWTN
760 770 780 790 800
DTGFLSYKEH LPVTKIVITD TGRPHSEAAY KLGPLLCRGD RPFWNAASFN
810 820 830 840 850
TEASYLHFPT FHGELSADVS FFFKTTALSG VFLENLGITD FIRIELRSPT
860 870 880 890 900
TVTFSFDVGN GPFELSVHSP THFNDNQWHH VRVERNMKEA SLRVDELPPK
910 920 930 940 950
IQAAPTDGHV LLQLNSQLFV GGTATRQRGF LGCIRSLQLN GMALDLEERA
960 970 980 990 1000
TVTPGVQPGC RGHCGSYGKL CRHGGKCREK PSGFFCDCSS SAYAGPFCSK
1010 1020 1030 1040 1050
EISAYFGSGS SVIYNFQENY SLSKNSSFHA ASFHGDMKLS REMIKFSFRT
1060 1070 1080 1090 1100
TRAPSLLLHM SSFYKEYLSI IIAKNGSLQI RYKLNKYHEP DVISFDLKSM
1110 1120 1130 1140 1150
ADGQLHHIKI NREEGMVFVE IDENTRRQTY LSSGTEFSAV KSLVLGRMLE
1160 1170 1180 1190 1200
YSDVDQETAL AAAHGFTGCL SAVQFSHIAP LKAALQPGPP APVTVTGHVT
1210 1220 1230 1240 1250
ESSCVAPSGT DATSRERTHS FADHSGTMDD REPLTHAIKS DSAVIGGLIA
1260 1270 1280 1290 1300
VVIFILLCVS AIAVRIYQQK RLYKRNEAKR SENVDSAEAV LKSELHIQNA
1310
VGENQKEYFF
Length:1,310
Mass (Da):144,730
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBEC6AB0A11DE6A14
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YWB9D3YWB9_MOUSE
Contactin-associated protein-like 4
Cntnap4
1,310Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti993Y → F in AAG52890 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF333770 mRNA Translation: AAG52890.1
AK142816 mRNA Translation: BAE25200.1
CH466525 Genomic DNA Translation: EDL11532.1
BC034628 mRNA Translation: AAH34628.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40482.1

NCBI Reference Sequences

More...
RefSeqi
NP_569724.2, NM_130457.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000034225; ENSMUSP00000034225; ENSMUSG00000031772

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
170571

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:170571

UCSC genome browser

More...
UCSCi
uc009nnj.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF333770 mRNA Translation: AAG52890.1
AK142816 mRNA Translation: BAE25200.1
CH466525 Genomic DNA Translation: EDL11532.1
BC034628 mRNA Translation: AAH34628.1
CCDSiCCDS40482.1
RefSeqiNP_569724.2, NM_130457.2

3D structure databases

SMRiQ99P47
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112511

PTM databases

GlyConnecti2232
iPTMnetiQ99P47
PhosphoSitePlusiQ99P47

Proteomic databases

MaxQBiQ99P47
PaxDbiQ99P47
PRIDEiQ99P47

Genome annotation databases

EnsembliENSMUST00000034225; ENSMUSP00000034225; ENSMUSG00000031772
GeneIDi170571
KEGGimmu:170571
UCSCiuc009nnj.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
85445
MGIiMGI:2183572 Cntnap4

Phylogenomic databases

eggNOGiKOG3516 Eukaryota
ENOG410XPHG LUCA
GeneTreeiENSGT00940000157674
InParanoidiQ99P47
OrthoDBi338397at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cntnap4 mouse

Protein Ontology

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PROi
PR:Q99P47

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000031772 Expressed in 102 organ(s), highest expression level in substantia nigra
ExpressionAtlasiQ99P47 baseline and differential
GenevisibleiQ99P47 MM

Family and domain databases

CDDicd00057 FA58C, 1 hit
Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR028875 CASPR4
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G
PANTHERiPTHR15036:SF40 PTHR15036:SF40, 1 hit
PfamiView protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits
SMARTiView protein in SMART
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 2 hits
PS01285 FA58C_1, 1 hit
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCNTP4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99P47
Secondary accession number(s): Q8K002
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: July 27, 2011
Last modified: October 16, 2019
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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