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Protein
Submitted name:

Peroxisome proliferator activated receptor delta, isoform CRA_b

Gene

Ppard

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-200425 Import of palmitoyl-CoA into the mitochondrial matrix
R-RNO-204174 Regulation of pyruvate dehydrogenase (PDH) complex
R-RNO-383280 Nuclear Receptor transcription pathway
R-RNO-5362517 Signaling by Retinoic Acid

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator activated receptor delta, isoform CRA_bImported
Submitted name:
Peroxisome proliferator-activated receptor betaImported
Submitted name:
Peroxisome proliferator-activated receptor deltaImported
Gene namesi
Name:PpardImported
Synonyms:PPARbImported
ORF Names:rCG_60581Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi3370 Ppard

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ99ND3

Expressioni

Gene expression databases

BgeeiENSRNOG00000000503 Expressed in 9 organ(s), highest expression level in colon

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000045974

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 144Nuclear receptorInterPro annotationAdd BLAST75
Domaini210 – 438NR LBDInterPro annotationAdd BLAST229

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136388
HOVERGENiHBG106004
KOiK04504
OMAiSLGMSHN
TreeFamiTF316304

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003074 1Cnucl_rcpt
IPR003075 1Cnucl_rcpt_B
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01288 PROXISOMEPAR
PR01290 PROXISOMPABR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q99ND3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQPQEETPE AREEEKEEVA TGDGAPELNG GPEHTLPSSS CTDLSQNSSP
60 70 80 90 100
SSLLDQLQMG CDGASGGSLN MECRVCGDKA SGFHYGVHAC EGCKGFFRRT
110 120 130 140 150
IRMKLKYEKC DRICKIQKKN RNKCQYCRFQ KCLALGMSHN AIRFGRMPEA
160 170 180 190 200
EKRKLVAGLT ASEGCQQNPQ LADLKAFSKH IYNAYLKNFN MTKKKARSIL
210 220 230 240 250
TGKSSHNAPF IIHDIETLWQ AEKGLVWKQL VNGPPPYNEI SVHVFYRCQS
260 270 280 290 300
TTVETVRELT EFAKNIPNFS SLFLNDQVTL LKYGVHEAIF AMLASIVNKD
310 320 330 340 350
GLLVANGSGF VTHEFLRSIR KPFSDIIEPK FEFAVKFNAL ELDDSDLALF
360 370 380 390 400
IAAIILCGDR PGLMNVPQVE AIQDTILQAL EFHLQVNHPD SQYLFPKLLQ
410 420 430 440
KMADLRQLVT EHAQMMQWLK KTESETLLHP LLQEIYKDMY
Length:440
Mass (Da):49,675
Last modified:June 1, 2001 - v1
Checksum:i362F943C37D4CFF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106225 Genomic DNA No translation available.
AC132760 Genomic DNA No translation available.
AJ306400 mRNA Translation: CAC29088.1
CH473988 Genomic DNA Translation: EDL96915.1
RefSeqiNP_037273.2, NM_013141.2
XP_006256228.1, XM_006256166.3
XP_006256229.1, XM_006256167.3
XP_006256230.1, XM_006256168.3
UniGeneiRn.96181

Genome annotation databases

EnsembliENSRNOT00000042539; ENSRNOP00000045974; ENSRNOG00000000503
ENSRNOT00000083109; ENSRNOP00000069522; ENSRNOG00000000503
GeneIDi25682
KEGGirno:25682

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106225 Genomic DNA No translation available.
AC132760 Genomic DNA No translation available.
AJ306400 mRNA Translation: CAC29088.1
CH473988 Genomic DNA Translation: EDL96915.1
RefSeqiNP_037273.2, NM_013141.2
XP_006256228.1, XM_006256166.3
XP_006256229.1, XM_006256167.3
XP_006256230.1, XM_006256168.3
UniGeneiRn.96181

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000045974

Proteomic databases

PRIDEiQ99ND3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000042539; ENSRNOP00000045974; ENSRNOG00000000503
ENSRNOT00000083109; ENSRNOP00000069522; ENSRNOG00000000503
GeneIDi25682
KEGGirno:25682

Organism-specific databases

CTDi5467
RGDi3370 Ppard

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136388
HOVERGENiHBG106004
KOiK04504
OMAiSLGMSHN
TreeFamiTF316304

Enzyme and pathway databases

ReactomeiR-RNO-200425 Import of palmitoyl-CoA into the mitochondrial matrix
R-RNO-204174 Regulation of pyruvate dehydrogenase (PDH) complex
R-RNO-383280 Nuclear Receptor transcription pathway
R-RNO-5362517 Signaling by Retinoic Acid

Gene expression databases

BgeeiENSRNOG00000000503 Expressed in 9 organ(s), highest expression level in colon

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003074 1Cnucl_rcpt
IPR003075 1Cnucl_rcpt_B
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01288 PROXISOMEPAR
PR01290 PROXISOMPABR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ99ND3_RAT
AccessioniPrimary (citable) accession number: Q99ND3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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