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Protein

39S ribosomal protein L3, mitochondrial

Gene

Mrpl3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L3, mitochondrial
Short name:
L3mt
Short name:
MRP-L3
Gene namesi
Name:Mrpl3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2137204 Mrpl3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 40MitochondrionBy similarityAdd BLAST40
ChainiPRO_000007725441 – 34839S ribosomal protein L3, mitochondrialAdd BLAST308

Proteomic databases

EPDiQ99N95
MaxQBiQ99N95
PaxDbiQ99N95
PRIDEiQ99N95

PTM databases

iPTMnetiQ99N95
PhosphoSitePlusiQ99N95

Expressioni

Gene expression databases

BgeeiENSMUSG00000032563 Expressed in 266 organ(s), highest expression level in metanephric renal vesicle
CleanExiMM_MRPL3
ExpressionAtlasiQ99N95 baseline and differential
GenevisibleiQ99N95 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi220434, 1 interactor
IntActiQ99N95, 3 interactors
MINTiQ99N95
STRINGi10090.ENSMUSP00000035177

Structurei

3D structure databases

ProteinModelPortaliQ99N95
SMRiQ99N95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3141 Eukaryota
COG0087 LUCA
GeneTreeiENSGT00390000011422
HOGENOMiHOG000100369
HOVERGENiHBG002294
InParanoidiQ99N95
KOiK02906
OMAiKDEPWPL
OrthoDBiEOG091G0BKZ
PhylomeDBiQ99N95
TreeFamiTF105634

Family and domain databases

InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019927 Ribosomal_L3_bac/org-type
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11229 PTHR11229, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03625 L3_bact, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.iShow all

Q99N95-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGWRLLAQA GARVLGCGAR GLGADPGLER RKNILFFVRN LHSKSSTWWD
60 70 80 90 100
EHLSEENLSF VKQLVSDENK TQLTSKLNPL KDEPWPLHPW EPGSFRVGLI
110 120 130 140 150
ALKLGMMPLW TKDGQKHAVT LLQVQDCHVL KYTPKEDHNG KIAALTVGGK
160 170 180 190 200
TVSRFYKPDS RLEFYRDLGL PPKQIHKIFH VTDNAVIKPG TPLYAAHFRP
210 220 230 240 250
GQYVDVTAKT IGKGFQGVMK RWGFKGQPAS HGQTKTHRRP GAISTGDIAR
260 270 280 290 300
VWPGTKMPGR MGNQNRTVYG LKVWRVNTKH NIIYVNGSVP GHKNCLVKIK
310 320 330 340
DSTLPAYKDS CKNLPFPTYF PDGDEEELPE DLFDESVWQP SEPSITFA
Length:348
Mass (Da):39,110
Last modified:June 1, 2001 - v1
Checksum:iA4596B5BAC91EFF9
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z456D3Z456_MOUSE
39S ribosomal protein L3, mitochond...
Mrpl3 mCG_14748
304Annotation score:
F6W7C7F6W7C7_MOUSE
39S ribosomal protein L3, mitochond...
Mrpl3
156Annotation score:
A0A1L1SU47A0A1L1SU47_MOUSE
39S ribosomal protein L3, mitochond...
Mrpl3
137Annotation score:
D6RI16D6RI16_MOUSE
39S ribosomal protein L3, mitochond...
Mrpl3
41Annotation score:
A0A087WQU4A0A087WQU4_MOUSE
39S ribosomal protein L3, mitochond...
Mrpl3
71Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049633 mRNA Translation: BAB40838.1
AK077857 mRNA Translation: BAC37036.1
AK145687 mRNA Translation: BAE26589.1
AK169272 mRNA Translation: BAE41032.1
BC034877 mRNA Translation: AAH34877.1
CCDSiCCDS23462.1
RefSeqiNP_444389.2, NM_053159.3
UniGeneiMm.29746

Genome annotation databases

EnsembliENSMUST00000035177; ENSMUSP00000035177; ENSMUSG00000032563
GeneIDi94062
KEGGimmu:94062
UCSCiuc009rht.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRM03_MOUSE
AccessioniPrimary (citable) accession number: Q99N95
Secondary accession number(s): Q3TF66, Q9CVE4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2001
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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