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Protein

28S ribosomal protein S18a, mitochondrial

Gene

Mrps18a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • small ribosomal subunit rRNA binding Source: GO_Central
  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S18a, mitochondrial
Short name:
MRP-S18-a
Short name:
Mrps18a
Short name:
S18mt-a
Alternative name(s):
28S ribosomal protein S18-3, mitochondrial
Short name:
MRP-S18-3
Gene namesi
Name:Mrps18a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1915815 Mrps18a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 34MitochondrionSequence analysisAdd BLAST34
ChainiPRO_000003062635 – 19628S ribosomal protein S18a, mitochondrialAdd BLAST162

Proteomic databases

EPDiQ99N85
MaxQBiQ99N85
PaxDbiQ99N85
PRIDEiQ99N85

PTM databases

iPTMnetiQ99N85
PhosphoSitePlusiQ99N85
SwissPalmiQ99N85

Expressioni

Gene expression databases

CleanExiMM_MRPS18A

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024763

Structurei

3D structure databases

ProteinModelPortaliQ99N85
SMRiQ99N85
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3162 Eukaryota
COG0238 LUCA
HOGENOMiHOG000139370
HOVERGENiHBG058800
InParanoidiQ99N85
KOiK02963
PhylomeDBiQ99N85

Family and domain databases

Gene3Di4.10.640.10, 1 hit
InterProiView protein in InterPro
IPR001648 Ribosomal_S18
IPR036870 Ribosomal_S18_sf
PfamiView protein in Pfam
PF01084 Ribosomal_S18, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002239 Ribosomal_S18, 1 hit
SUPFAMiSSF46911 SSF46911, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q99N85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAALRRLVSG CGRQLQAFLA GPAATGWLWL PARGLREVVK IQEGKTTVIE
60 70 80 90 100
GRITETPKAT PDPPNPSGQC PICRWNLKHK YTYEDVLLLS QFIRPYGGML
110 120 130 140 150
PRRVTGLCRE EHRKIEECVK MAHRAGLLPN HRPQLPEGCL PKDKPKLNRY
160 170 180 190
LTRWAPKSVK PIYKKGHRWN KVGMAVGSPL LKDNVCYSRR PLKMMH
Length:196
Mass (Da):22,321
Last modified:June 1, 2001 - v1
Checksum:i1E0CB8F311F19E0F
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5U5I3Q5U5I3_MOUSE
28S ribosomal protein S18a, mitocho...
Mrps18a mCG_2525
196Annotation score:
D3Z603D3Z603_MOUSE
28S ribosomal protein S18a, mitocho...
Mrps18a mCG_2525
149Annotation score:

Sequence cautioni

The sequence AAH25456 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6R → A in BAB22794 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049953 mRNA Translation: BAB41006.1
AK003444 mRNA Translation: BAB22794.1
BC025456 mRNA Translation: AAH25456.1 Different initiation.
CCDSiCCDS28819.1
RefSeqiNP_081044.1, NM_026768.3
UniGeneiMm.287443

Genome annotation databases

GeneIDi68565
KEGGimmu:68565

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049953 mRNA Translation: BAB41006.1
AK003444 mRNA Translation: BAB22794.1
BC025456 mRNA Translation: AAH25456.1 Different initiation.
CCDSiCCDS28819.1
RefSeqiNP_081044.1, NM_026768.3
UniGeneiMm.287443

3D structure databases

ProteinModelPortaliQ99N85
SMRiQ99N85
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024763

PTM databases

iPTMnetiQ99N85
PhosphoSitePlusiQ99N85
SwissPalmiQ99N85

Proteomic databases

EPDiQ99N85
MaxQBiQ99N85
PaxDbiQ99N85
PRIDEiQ99N85

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi68565
KEGGimmu:68565

Organism-specific databases

CTDi55168
MGIiMGI:1915815 Mrps18a

Phylogenomic databases

eggNOGiKOG3162 Eukaryota
COG0238 LUCA
HOGENOMiHOG000139370
HOVERGENiHBG058800
InParanoidiQ99N85
KOiK02963
PhylomeDBiQ99N85

Miscellaneous databases

ChiTaRSiMrps18a mouse
PROiPR:Q99N85
SOURCEiSearch...

Gene expression databases

CleanExiMM_MRPS18A

Family and domain databases

Gene3Di4.10.640.10, 1 hit
InterProiView protein in InterPro
IPR001648 Ribosomal_S18
IPR036870 Ribosomal_S18_sf
PfamiView protein in Pfam
PF01084 Ribosomal_S18, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002239 Ribosomal_S18, 1 hit
SUPFAMiSSF46911 SSF46911, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT18A_MOUSE
AccessioniPrimary (citable) accession number: Q99N85
Secondary accession number(s): Q8R3H2, Q9D1J6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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