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Entry version 158 (29 Sep 2021)
Sequence version 2 (25 Jul 2003)
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Protein

Synaptotagmin-like protein 3

Gene

Sytl3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Synaptotagmin-like protein 3
Alternative name(s):
Exophilin-6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sytl3
Synonyms:Slp3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1933367, Sytl3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000041831

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi336 – 337EE → QQ: Binds phospholipids only in the absence of divalent cations. 1 Publication2
Mutagenesisi359 – 361KRK → QQQ: Binds phospholipids only in the absence of divalent cations. 1 Publication3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001902151 – 607Synaptotagmin-like protein 3Add BLAST607

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q99N48

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q99N48

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q99N48

PRoteomics IDEntifications database

More...
PRIDEi
Q99N48

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
254848 [Q99N48-1]
254849 [Q99N48-2]
254850 [Q99N48-3]
254851 [Q99N48-4]
254852 [Q99N48-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q99N48

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q99N48

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in spleen and lung. Detected at lower levels in heart and testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000041831, Expressed in thymus and 105 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q99N48, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q99N48, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus.

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q99N48, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000125469

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q99N48, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q99N48

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 123RabBDPROSITE-ProRule annotationAdd BLAST120
Domaini305 – 430C2 1PROSITE-ProRule annotationAdd BLAST126
Domaini458 – 590C2 2PROSITE-ProRule annotationAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni221 – 279DisorderedSequence analysisAdd BLAST59

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi226 – 242Polar residuesSequence analysisAdd BLAST17
Compositional biasi246 – 261Basic and acidic residuesSequence analysisAdd BLAST16

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1028, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160610

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002711_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q99N48

Identification of Orthologs from Complete Genome Data

More...
OMAi
SHEYQER

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q99N48

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04020, C2B_SLP_1-2-3-4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR041282, FYVE_2
IPR010911, Rab_BD
IPR043567, SYTL1-5_C2B
IPR028704, SYTL3
IPR011011, Znf_FYVE_PHD
IPR013083, Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR45716:SF1, PTHR45716:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 2 hits
PF02318, FYVE_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49562, SSF49562, 2 hits
SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 2 hits
PS50916, RABBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q99N48-1) [UniParc]FASTAAdd to basket
Also known as: Slp3-a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAHEVDLESF KELERDIILR VLYRDQTVQS TEEERVRKLK SHLQHLRWKG
60 70 80 90 100
AKSSSQEYKE KCCARCQRAL GLLLNRGAVC QGCSHRVCSE CRVFLRRTRA
110 120 130 140 150
WKCTVCFEDR NVKIKTGEWF FEERARKFPT AGRRETAGAK LLQSYQRLSK
160 170 180 190 200
ISVVPPTPPP FSESQCSSSS RLQELGHFRG FNKSVENLFL SVTTQMRKLS
210 220 230 240 250
KSQNDMTSEK HLLAMDPRQC VGHTERRSQS DTAVNVTSRK ASTPDILKAF
260 270 280 290 300
HQEDPKHPPD PVLKQDTPPS SPTHSAVFSG GLRHGSLISI NSTCTEMGNF
310 320 330 340 350
DNANVTGEIE FAIHYCVKSC SLEICIKTCK NLAYGEEKKR KCNPYVKTYL
360 370 380 390 400
LPDRSSQGKR KTRVQKNTLD PTFEETLKYQ VDPGQLMTRR LQVSVWHLGT
410 420 430 440 450
LARRVFLGEV ILPLAMWDFK DSTAQNARWY PLRAKAEKYE ENIPQNNGEL
460 470 480 490 500
AVRAKLVLPA GPRKPQEAQE GQLALNGQLC LVVLGAKNLP VRSDGTLNSF
510 520 530 540 550
VKGCLTLPNQ QKLRVKSPVL KKQACPQWKH SFVFNGVSSS QLRQSTLELT
560 570 580 590 600
VWDQAIFGMN DRLLGEARLG SKGGAAGCPD SGSQSKLQWH RVLSSPNLWT

DMTLVLH
Length:607
Mass (Da):68,568
Last modified:July 25, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF9F404D2D77A6351
GO
Isoform 2 (identifier: Q99N48-2) [UniParc]FASTAAdd to basket
Also known as: Slp3-a + 3S-I

The sequence of this isoform differs from the canonical sequence as follows:
     1-195: Missing.

Show »
Length:412
Mass (Da):45,955
Checksum:iAB1EDD538CCCB218
GO
Isoform 3 (identifier: Q99N48-3) [UniParc]FASTAAdd to basket
Also known as: Slp3-b, Slp3-a delta 3S-II

The sequence of this isoform differs from the canonical sequence as follows:
     1-214: Missing.

Show »
Length:393
Mass (Da):43,755
Checksum:iD6D27768F455F91B
GO
Isoform 4 (identifier: Q99N48-4) [UniParc]FASTAAdd to basket
Also known as: Slp3-b + 3S-III

The sequence of this isoform differs from the canonical sequence as follows:
     1-296: Missing.

Show »
Length:311
Mass (Da):34,884
Checksum:i91986B928DC510E0
GO
Isoform 5 (identifier: Q99N48-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     111-114: NVKI → ANGR
     115-607: Missing.

Show »
Length:114
Mass (Da):13,429
Checksum:i5EBD2E5BBFDAE4C6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PXV1E9PXV1_MOUSE
Synaptotagmin-like protein 3
Sytl3
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PUK9E9PUK9_MOUSE
Synaptotagmin-like protein 3
Sytl3
402Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYJ1E0CYJ1_MOUSE
Synaptotagmin-like protein 3
Sytl3
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WHG0F8WHG0_MOUSE
Synaptotagmin-like protein 3
Sytl3
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti229Q → R in BAB32653 (PubMed:11243866).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0078971 – 296Missing in isoform 4. 1 PublicationAdd BLAST296
Alternative sequenceiVSP_0078961 – 214Missing in isoform 3. 2 PublicationsAdd BLAST214
Alternative sequenceiVSP_0078951 – 195Missing in isoform 2. 2 PublicationsAdd BLAST195
Alternative sequenceiVSP_007898111 – 114NVKI → ANGR in isoform 5. 1 Publication4
Alternative sequenceiVSP_007899115 – 607Missing in isoform 5. 1 PublicationAdd BLAST493

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB050743 mRNA Translation: BAB32653.1
AB057758 mRNA Translation: BAB41086.1
AB057764 mRNA Translation: BAB41092.1
AB057765 mRNA Translation: BAB41093.1
AB057766 mRNA Translation: BAB41094.1
BC022608 mRNA Translation: AAH22608.1
BC106102 mRNA Translation: AAI06103.1
AK079850 mRNA Translation: BAC37766.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS28372.2 [Q99N48-1]
CCDS28374.3 [Q99N48-2]

NCBI Reference Sequences

More...
RefSeqi
NP_113572.1, NM_031395.2 [Q99N48-1]
NP_899226.2, NM_183370.2 [Q99N48-2]
XP_006523322.1, XM_006523259.2 [Q99N48-1]
XP_006523324.1, XM_006523261.3 [Q99N48-2]
XP_006523326.1, XM_006523263.1 [Q99N48-2]
XP_006523327.1, XM_006523264.1 [Q99N48-2]
XP_011244483.1, XM_011246181.2 [Q99N48-1]
XP_017173221.1, XM_017317732.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000097430; ENSMUSP00000095041; ENSMUSG00000041831 [Q99N48-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
83672

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:83672

UCSC genome browser

More...
UCSCi
uc008ahq.2, mouse [Q99N48-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050743 mRNA Translation: BAB32653.1
AB057758 mRNA Translation: BAB41086.1
AB057764 mRNA Translation: BAB41092.1
AB057765 mRNA Translation: BAB41093.1
AB057766 mRNA Translation: BAB41094.1
BC022608 mRNA Translation: AAH22608.1
BC106102 mRNA Translation: AAI06103.1
AK079850 mRNA Translation: BAC37766.1
CCDSiCCDS28372.2 [Q99N48-1]
CCDS28374.3 [Q99N48-2]
RefSeqiNP_113572.1, NM_031395.2 [Q99N48-1]
NP_899226.2, NM_183370.2 [Q99N48-2]
XP_006523322.1, XM_006523259.2 [Q99N48-1]
XP_006523324.1, XM_006523261.3 [Q99N48-2]
XP_006523326.1, XM_006523263.1 [Q99N48-2]
XP_006523327.1, XM_006523264.1 [Q99N48-2]
XP_011244483.1, XM_011246181.2 [Q99N48-1]
XP_017173221.1, XM_017317732.1

3D structure databases

SMRiQ99N48
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ99N48, 2 interactors
STRINGi10090.ENSMUSP00000125469

PTM databases

iPTMnetiQ99N48
PhosphoSitePlusiQ99N48

Proteomic databases

EPDiQ99N48
jPOSTiQ99N48
PaxDbiQ99N48
PRIDEiQ99N48
ProteomicsDBi254848 [Q99N48-1]
254849 [Q99N48-2]
254850 [Q99N48-3]
254851 [Q99N48-4]
254852 [Q99N48-5]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
33442, 109 antibodies

The DNASU plasmid repository

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DNASUi
83672

Genome annotation databases

EnsembliENSMUST00000097430; ENSMUSP00000095041; ENSMUSG00000041831 [Q99N48-1]
GeneIDi83672
KEGGimmu:83672
UCSCiuc008ahq.2, mouse [Q99N48-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
94120
MGIiMGI:1933367, Sytl3
VEuPathDBiHostDB:ENSMUSG00000041831

Phylogenomic databases

eggNOGiKOG1028, Eukaryota
GeneTreeiENSGT00940000160610
HOGENOMiCLU_002711_0_0_1
InParanoidiQ99N48
OMAiSHEYQER
PhylomeDBiQ99N48

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
83672, 8 hits in 63 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Sytl3, mouse

Protein Ontology

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PROi
PR:Q99N48
RNActiQ99N48, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000041831, Expressed in thymus and 105 other tissues
ExpressionAtlasiQ99N48, baseline and differential
GenevisibleiQ99N48, MM

Family and domain databases

CDDicd04020, C2B_SLP_1-2-3-4, 1 hit
Gene3Di2.60.40.150, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR041282, FYVE_2
IPR010911, Rab_BD
IPR043567, SYTL1-5_C2B
IPR028704, SYTL3
IPR011011, Znf_FYVE_PHD
IPR013083, Znf_RING/FYVE/PHD
PANTHERiPTHR45716:SF1, PTHR45716:SF1, 1 hit
PfamiView protein in Pfam
PF00168, C2, 2 hits
PF02318, FYVE_2, 1 hit
SMARTiView protein in SMART
SM00239, C2, 2 hits
SUPFAMiSSF49562, SSF49562, 2 hits
SSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 2 hits
PS50916, RABBD, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYTL3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99N48
Secondary accession number(s): Q3KQQ0
, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: July 25, 2003
Last modified: September 29, 2021
This is version 158 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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