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Protein

Ferritin heavy polypeptide-like 17

Gene

Fthl17

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27IronPROSITE-ProRule annotation1
Metal bindingi107IronPROSITE-ProRule annotation1
Metal bindingi141IronPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIron storage
LigandIron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferritin heavy polypeptide-like 17
Gene namesi
Name:Fthl17
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1933180 Fthl17

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010691 – 176Ferritin heavy polypeptide-like 17Add BLAST176

Proteomic databases

PaxDbiQ99MX2
PRIDEiQ99MX2

Expressioni

Tissue specificityi

Testis specific.

Gene expression databases

BgeeiENSMUSG00000071815 Expressed in 2 organ(s), highest expression level in testis
CleanExiMM_FTHL17
GenevisibleiQ99MX2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094254

Structurei

3D structure databases

ProteinModelPortaliQ99MX2
SMRiQ99MX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 159Ferritin-like diironPROSITE-ProRule annotationAdd BLAST150

Sequence similaritiesi

Belongs to the ferritin family.Curated

Phylogenomic databases

eggNOGiKOG2332 Eukaryota
COG1528 LUCA
GeneTreeiENSGT00760000119129
HOGENOMiHOG000223383
HOVERGENiHBG000410
InParanoidiQ99MX2
OrthoDBiEOG091G0KPY
PhylomeDBiQ99MX2

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR014034 Ferritin_CS
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS00204 FERRITIN_2, 1 hit
PS50905 FERRITIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q99MX2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEAPSRMQQ NYDWQCEDAI NTHIQLCLYA SYEYMSMAVY FDRDDVAQEN
60 70 80 90 100
FKRFFLTKSH NCQTSAEMFM HLQNKRGGCS SLQGIARPER DSWHGGFQAM
110 120 130 140 150
ECAFHMEMLI NQSLLNMHEV AKEKGDPHLC HFLEQNCLDQ QVDILKEMSG
160 170
YLTNLRQMGA VEHNLAEYLF DKLSLS
Length:176
Mass (Da):20,491
Last modified:September 18, 2013 - v2
Checksum:i590A4D44F063324C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80S → I in AAK31948 (PubMed:11279525).Curated1
Sequence conflicti84G → D in AAK31948 (PubMed:11279525).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285569 mRNA Translation: AAK31948.1
AL806531 Genomic DNA No translation available.
CCDSiCCDS30003.1
RefSeqiNP_112551.2, NM_031261.2
UniGeneiMm.388703

Genome annotation databases

EnsembliENSMUST00000096509; ENSMUSP00000094254; ENSMUSG00000071815
GeneIDi83457
KEGGimmu:83457
UCSCiuc009spm.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285569 mRNA Translation: AAK31948.1
AL806531 Genomic DNA No translation available.
CCDSiCCDS30003.1
RefSeqiNP_112551.2, NM_031261.2
UniGeneiMm.388703

3D structure databases

ProteinModelPortaliQ99MX2
SMRiQ99MX2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094254

Proteomic databases

PaxDbiQ99MX2
PRIDEiQ99MX2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000096509; ENSMUSP00000094254; ENSMUSG00000071815
GeneIDi83457
KEGGimmu:83457
UCSCiuc009spm.1 mouse

Organism-specific databases

CTDi83457
MGIiMGI:1933180 Fthl17

Phylogenomic databases

eggNOGiKOG2332 Eukaryota
COG1528 LUCA
GeneTreeiENSGT00760000119129
HOGENOMiHOG000223383
HOVERGENiHBG000410
InParanoidiQ99MX2
OrthoDBiEOG091G0KPY
PhylomeDBiQ99MX2

Miscellaneous databases

PROiPR:Q99MX2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000071815 Expressed in 2 organ(s), highest expression level in testis
CleanExiMM_FTHL17
GenevisibleiQ99MX2 MM

Family and domain databases

Gene3Di1.20.1260.10, 1 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR014034 Ferritin_CS
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS00204 FERRITIN_2, 1 hit
PS50905 FERRITIN_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiFHL17_MOUSE
AccessioniPrimary (citable) accession number: Q99MX2
Secondary accession number(s): L7MU38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: September 18, 2013
Last modified: September 12, 2018
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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