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UniProtKB - Q99ME2 (WDR6_MOUSE)

Entry version 153 (02 Dec 2020)
Sequence version 1 (01 Jun 2001)
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Protein

WD repeat-containing protein 6

Gene

Wdr6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat-containing protein 6
Short name:
mWDR6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Wdr6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1930140, Wdr6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003934601 – 1125WD repeat-containing protein 6Add BLAST1125

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q99ME2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q99ME2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q99ME2

PRoteomics IDEntifications database

More...PRIDEi		Q99ME2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q99ME2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q99ME2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000066357, Expressed in arcuate nucleus of hypothalamus and 308 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q99ME2, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STK11/LKB1.

Interacts with IRS4 (By similarity).

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		219954, 35 interactors

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000070927

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q99ME2, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati53 – 97WD 1Add BLAST45
Repeati105 – 143WD 2Add BLAST39
Repeati147 – 189WD 3Add BLAST43
Repeati200 – 238WD 4Add BLAST39
Repeati247 – 285WD 5Add BLAST39
Repeati289 – 327WD 6Add BLAST39
Repeati335 – 376WD 7Add BLAST42
Repeati381 – 422WD 8Add BLAST42
Repeati425 – 470WD 9Add BLAST46
Repeati476 – 520WD 10Add BLAST45
Repeati559 – 598WD 11Add BLAST40
Repeati604 – 642WD 12Add BLAST39
Repeati645 – 684WD 13Add BLAST40
Repeati739 – 785WD 14Add BLAST47
Repeati848 – 897WD 15Add BLAST50
Repeati905 – 950WD 16Add BLAST46
Repeati974 – 1016WD 17Add BLAST43
Repeati1040 – 1077WD 18Add BLAST38
Repeati1083 – 1125WD 19Add BLAST43

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat WDR6 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0974, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00420000029923

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002615_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q99ME2

Identification of Orthologs from Complete Genome Data

More...OMAi		HFFTGHE

Database of Orthologous Groups

More...OrthoDBi		555109at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q99ME2

TreeFam database of animal gene trees

More...TreeFami		TF313984

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00400, WD40, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00320, WD40, 8 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q99ME2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAFGDYVWP RATSELILLP VTGLECVGDR LLAGEGPDLL VYNLDLGGHL 
        60         70         80         90        100
RMVKRVQNLL GHFLIHGFRV RPEPKGDLDS EAMIAVFGSK GLKVVKVSWG 
       110        120        130        140        150
QSHLRELWRS GLWNMSDWIW DVRWIEGNVA VALGHNSVVL YDPVIGCMLQ 
       160        170        180        190        200
DVPCTDRCTL SSACLVGDTW KELTIVAGAV SNELLIWYPA TALTDNKPVA 
       210        220        230        240        250
PDRRVSGHVG VIFSMSYLES KGLLATASED RSVRLWKVGD LRVPGGRVQN 
       260        270        280        290        300
IGHCFGHSAR VWQVKLLENY LISAGEDCVC LVWSHEGEIL QAFRGHRGRG 
       310        320        330        340        350
IRAIATHERQ AWVVTGGDDS GIRLWHLAGR GYPGLGVSSL SFKSPSRPGA 
       360        370        380        390        400
LKAVTLAGSW RVLAVTDVGS LYLYDLEVKS WEQLLEDNRF RSYCLLEAAP 
       410        420        430        440        450
GPEGFGLCAL ANGEGLVKVV PINTPTAAVE QKLFQGKVHS LSWALRGYEE 
       460        470        480        490        500
LLLLASGPGG VIACLEISAA PTGKAIFVKE RCRYLLPPSK QRWHTCSAFL 
       510        520        530        540        550
PPGDFLVCGD RRGSVMLFPV RPCLFKKPGA GSKAITAAEA PGAGSGSGGS 
       560        570        580        590        600
ESVPTGIGPV STLHSLHGKQ GVTSVTCHGG YLYSTGRDSS YFQLFVHGGH 
       610        620        630        640        650
LQPVLRQKAC RGMNWVAGLR MVPDGSMVIL GFHANEFVVW SPRSHEKLHI 
       660        670        680        690        700
VNCGGGHRSW AFSDTEAAMA FTYLKDGEVM LYRALGGCIR PNVILREGLH 
       710        720        730        740        750
GREITCVKRV GTVTLGPEFE VPNLEHPDSL EPGSEGPGLI DIVITGSEDT 
       760        770        780        790        800
TVCVLALPTT TGSAHALTSV CNHISSVRAL AVWAVGTPGG PQDTRPGLTA 
       810        820        830        840        850
QVVSAGGRAE IHCFSVMVTP DASTPSRLAC HVMHLSSHRL DEYWDRQRNK 
       860        870        880        890        900
HKMIKVDPET RYMSLAICEL DNDRPGLGPG PLVAAACSDG AVRLFLLQDS 
       910        920        930        940        950
GRILHLLAES FHHKRCVLKV HSFTHEAPNQ RRRLILCSAA TDGSLAFWDL 
       960        970        980        990       1000
TTAMDKGSTT LELPAHPGLP YQMGTPSMTV QAHSCGVNSL HTLPTPEGHH 
      1010       1020       1030       1040       1050
LVASGSEDGS LHVFTLAVKM PEPEEADGEA ELVPQLCVLE EYSVPCAHAA 
      1060       1070       1080       1090       1100
HVTGVKILSP KLMVSASIDQ RLTFWRLGQG EPTFMNSTVY HVPDVADMDC 
      1110       1120 
WPVSPEFGHR CALAGQGLEV YNWYD
Length:1,125
Mass (Da):121,898
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF228CE5D71554766
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF348591 mRNA Translation: AAK31166.1
AK037181 mRNA Translation: BAC29740.1
AK146617 mRNA Translation: BAE27306.1
AK163752 mRNA Translation: BAE37480.1
CH466560 Genomic DNA Translation: EDL21306.1
BC050894 mRNA Translation: AAH50894.1
BC054367 mRNA Translation: AAH54367.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS23532.2

NCBI Reference Sequences

More...RefSeqi		NP_113569.1, NM_031392.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000068700; ENSMUSP00000070927; ENSMUSG00000066357

Database of genes from NCBI RefSeq genomes

More...GeneIDi		83669

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:83669

UCSC genome browser

More...UCSCi		uc009rqj.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF348591 mRNA Translation: AAK31166.1
AK037181 mRNA Translation: BAC29740.1
AK146617 mRNA Translation: BAE27306.1
AK163752 mRNA Translation: BAE37480.1
CH466560 Genomic DNA Translation: EDL21306.1
BC050894 mRNA Translation: AAH50894.1
BC054367 mRNA Translation: AAH54367.1
CCDSiCCDS23532.2
RefSeqiNP_113569.1, NM_031392.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi219954, 35 interactors
STRINGi10090.ENSMUSP00000070927

PTM databases

iPTMnetiQ99ME2
PhosphoSitePlusiQ99ME2

Proteomic databases

EPDiQ99ME2
MaxQBiQ99ME2
PaxDbiQ99ME2
PRIDEiQ99ME2

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		13436, 91 antibodies

Genome annotation databases

EnsembliENSMUST00000068700; ENSMUSP00000070927; ENSMUSG00000066357
GeneIDi83669
KEGGimmu:83669
UCSCiuc009rqj.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11180
MGIiMGI:1930140, Wdr6

Phylogenomic databases

eggNOGiKOG0974, Eukaryota
GeneTreeiENSGT00420000029923
HOGENOMiCLU_002615_0_0_1
InParanoidiQ99ME2
OMAiHFFTGHE
OrthoDBi555109at2759
PhylomeDBiQ99ME2
TreeFamiTF313984

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		83669, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Wdr6, mouse

Protein Ontology

More...PROi		PR:Q99ME2
RNActiQ99ME2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000066357, Expressed in arcuate nucleus of hypothalamus and 308 other tissues
GenevisibleiQ99ME2, MM

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400, WD40, 3 hits
SMARTiView protein in SMART
SM00320, WD40, 8 hits
SUPFAMiSSF50978, SSF50978, 3 hits
PROSITEiView protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDR6_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99ME2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: June 1, 2001
Last modified: December 2, 2020
This is version 153 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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