UniProtKB - Q99MB4 (CBWD1_RAT)
Protein
COBW domain-containing protein 1
Gene
Cbwd1
Organism
Rattus norvegicus (Rat)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 48 – 55 | ATPSequence analysis | 8 | |
Nucleotide bindingi | 109 – 113 | ATPSequence analysis | 5 | |
Nucleotide bindingi | 202 – 205 | ATPSequence analysis | 4 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
Keywordsi
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: COBW domain-containing protein 1Alternative name(s): Cobalamin synthase W domain-containing protein 1 |
Gene namesi | Name:Cbwd1 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 708495, Cbwd1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000245525 | 1 – 394 | COBW domain-containing protein 1Add BLAST | 394 |
Proteomic databases
jPOSTi | Q99MB4 |
PaxDbi | Q99MB4 |
PRIDEi | Q99MB4 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000015516, Expressed in testis and 20 other tissues |
Genevisiblei | Q99MB4, RN |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 272 – 375 | CobW C-terminalAdd BLAST | 104 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG2743, Eukaryota |
GeneTreei | ENSGT00640000091523 |
HOGENOMi | CLU_017452_0_1_1 |
InParanoidi | Q99MB4 |
OMAi | FFMDDEI |
OrthoDBi | 1144889at2759 |
PhylomeDBi | Q99MB4 |
TreeFami | TF332679 |
Family and domain databases
Gene3Di | 3.30.1220.10, 1 hit |
InterProi | View protein in InterPro IPR011629, Cbl_biosynth_CobW-like_C IPR036627, CobW-likC_sf IPR003495, CobW/HypB/UreG_dom IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF02492, cobW, 1 hit PF07683, CobW_C, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Complete.
Q99MB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPAMKTVEA EEEYAEDCPE LVPIETKHQE KEENLDFIIK IPVTIVTGYL
60 70 80 90 100
GAGKTTLLNY ILTEQHNRKI AVILNEFGEG SAVEKSLAVS QGGELYEEWL
110 120 130 140 150
ELRNGCLCCS VKDNGLKAIE NLMQKKGKFD YILLETTGLA DPGAVASMFW
160 170 180 190 200
VDAELGSDIY LDGIITVVDS KYGLKHLTEE KPDGLVNEAT RQVALADMIL
210 220 230 240 250
INKTDLVSEE ELNKLRTTIR SINGLGKVLE TQRSRTHLSN ILDLHAYDTL
260 270 280 290 300
SGISLQKKLQ HVSTAPHLDQ SIVTVTFDVP GSAEEESLNV FIQNLLWEKN
310 320 330 340 350
VKNKDGRCME VIRLKGLVSI KDKPQQMIVQ GIHELYELEE SRVNWKDDAE
360 370 380 390
RACQLVFIGK NLDKDILQQL FITAVAETKE QTTAPGQDGA CPPH
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 81 | S → N in AAK31208 (Ref. 1) Curated | 1 | |
Sequence conflicti | 99 | W → R in AAK31208 (Ref. 1) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF353305 mRNA Translation: AAK31208.1 BC086376 mRNA Translation: AAH86376.1 |
RefSeqi | NP_598219.2, NM_133535.2 |
Genome annotation databases
Ensembli | ENSRNOT00000021185; ENSRNOP00000021185; ENSRNOG00000015516 |
GeneIDi | 171057 |
KEGGi | rno:171057 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF353305 mRNA Translation: AAK31208.1 BC086376 mRNA Translation: AAH86376.1 |
RefSeqi | NP_598219.2, NM_133535.2 |
3D structure databases
SMRi | Q99MB4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000021185 |
Proteomic databases
jPOSTi | Q99MB4 |
PaxDbi | Q99MB4 |
PRIDEi | Q99MB4 |
Genome annotation databases
Ensembli | ENSRNOT00000021185; ENSRNOP00000021185; ENSRNOG00000015516 |
GeneIDi | 171057 |
KEGGi | rno:171057 |
Organism-specific databases
CTDi | 55871 |
RGDi | 708495, Cbwd1 |
Phylogenomic databases
eggNOGi | KOG2743, Eukaryota |
GeneTreei | ENSGT00640000091523 |
HOGENOMi | CLU_017452_0_1_1 |
InParanoidi | Q99MB4 |
OMAi | FFMDDEI |
OrthoDBi | 1144889at2759 |
PhylomeDBi | Q99MB4 |
TreeFami | TF332679 |
Miscellaneous databases
PROi | PR:Q99MB4 |
Gene expression databases
Bgeei | ENSRNOG00000015516, Expressed in testis and 20 other tissues |
Genevisiblei | Q99MB4, RN |
Family and domain databases
Gene3Di | 3.30.1220.10, 1 hit |
InterProi | View protein in InterPro IPR011629, Cbl_biosynth_CobW-like_C IPR036627, CobW-likC_sf IPR003495, CobW/HypB/UreG_dom IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF02492, cobW, 1 hit PF07683, CobW_C, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CBWD1_RAT | |
Accessioni | Q99MB4Primary (citable) accession number: Q99MB4 Secondary accession number(s): Q5RK12 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 11, 2006 |
Last sequence update: | July 11, 2006 | |
Last modified: | October 7, 2020 | |
This is version 91 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families