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Entry version 141 (02 Jun 2021)
Sequence version 1 (01 Jun 2001)
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Protein

V-type proton ATPase subunit C 2

Gene

Atp6v1c2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-1222556, ROS and RNS production in phagocytes
R-MMU-77387, Insulin receptor recycling
R-MMU-917977, Transferrin endocytosis and recycling
R-MMU-9639288, Amino acids regulate mTORC1
R-MMU-983712, Ion channel transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.2.2.6, the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
V-type proton ATPase subunit C 2
Short name:
V-ATPase subunit C 2
Alternative name(s):
Vacuolar proton pump subunit C 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Atp6v1c2
Synonyms:Atp6c2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1916025, Atp6v1c2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002856701 – 427V-type proton ATPase subunit C 2Add BLAST427

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q99L60

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q99L60

PRoteomics IDEntifications database

More...
PRIDEi
Q99L60

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
297536 [Q99L60-1]
297537 [Q99L60-2]
297538 [Q99L60-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q99L60

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q99L60

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Predominantly expressed in the lung and kidney. Isoform 1 is lung-specific while isoform 3 is a kidney-specific isoform. Isoform 1 is localized in the lamellar bodies of type II alveolar cells. Isoform 2 is strongly expressed in the cortical and medulla collecting ducts and is found in the plasma membranes of renal alpha and beta intercalated cells.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Significant expression seen at 17 dpc and not earlier.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000020566, Expressed in prostate gland and 111 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q99L60, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q99L60, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
213044, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000020884

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q99L60, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q99L60

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni298 – 320DisorderedSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the V-ATPase C subunit family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2909, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000004263

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q99L60

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPSYVQW

Database of Orthologous Groups

More...
OrthoDBi
1016088at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q99L60

TreeFam database of animal gene trees

More...
TreeFami
TF314912

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14785, V-ATPase_C, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004907, ATPase_V1-cplx_csu
IPR036132, Vac_ATP_synth_c_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10137, PTHR10137, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03223, V-ATPase_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF118203, SSF118203, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q99L60-1) [UniParc]FASTAAdd to basket
Also known as: C2-a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEFWLISAP GDKENLQALE RMNNVTSKSN LSHNTKFAIP DFKVGTLDSL
60 70 80 90 100
VGLSDELGKL DTFAESLIKR MAQSVVEVME DSKGKAHETL LANGVDLTSF
110 120 130 140 150
VTHFEWDMAK YPAKQPLVSV VDTLAKQLAQ IETDLKSRTA AYSVLKANLE
160 170 180 190 200
NLEKRSTGNL FTRTLSDIVS KEDFVLDSEY LITLLVIVPK SSFAQWQKTY
210 220 230 240 250
ESLSDMVVPR STKLIAEDNE GGLFTVTLFR KVIEDFKVKA KENKFIVREF
260 270 280 290 300
YYDEKEIKRE REEMTRLLSD KKQQYPTSCV ALKKGSATYR DHKVKVAPLG
310 320 330 340 350
NPARPAAGQT DRDRESEGEG EGPLLRWLKV NFSEAFIAWI HIKALRVFVE
360 370 380 390 400
SVLRYGLPVN FQAVLLQPHK KSATKRLREV LNSVFRHLDE VAAASILDAS
410 420
VEIPGLQLSN QDYFPYVYFH IDLSLLD
Length:427
Mass (Da):48,350
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D7146D9BC7F03F7
GO
Isoform 2 (identifier: Q99L60-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     95-95: V → GLKEKMKCLKI

Show »
Length:437
Mass (Da):49,524
Checksum:i2DAE84F4DB6006EC
GO
Isoform 3 (identifier: Q99L60-3) [UniParc]FASTAAdd to basket
Also known as: C2-b

The sequence of this isoform differs from the canonical sequence as follows:
     276-321: Missing.

Show »
Length:381
Mass (Da):43,517
Checksum:iEEC1EB557D239F62
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z5W3D3Z5W3_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
357Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RCW6D6RCW6_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
187Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z1Q7D3Z1Q7_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
134Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YVW5D3YVW5_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
70Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YZX0D3YZX0_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
63Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VLG0A0A1Y7VLG0_MOUSE
V-type proton ATPase subunit C
Atp6v1c2
102Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti125A → T in AAH56636 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02488495V → GLKEKMKCLKI in isoform 2. 1 Publication1
Alternative sequenceiVSP_024885276 – 321Missing in isoform 3. 2 PublicationsAdd BLAST46

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB088357 mRNA Translation: BAC57950.1
BC003810 mRNA Translation: AAH03810.1
BC056636 mRNA Translation: AAH56636.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25827.1 [Q99L60-1]
CCDS49034.1 [Q99L60-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001153104.1, NM_001159632.1 [Q99L60-2]
NP_598460.1, NM_133699.2 [Q99L60-1]
XP_006515259.1, XM_006515196.3 [Q99L60-2]
XP_006515262.1, XM_006515199.3 [Q99L60-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000020884; ENSMUSP00000020884; ENSMUSG00000020566 [Q99L60-2]
ENSMUST00000095820; ENSMUSP00000093500; ENSMUSG00000020566 [Q99L60-1]
ENSMUST00000221129; ENSMUSP00000152515; ENSMUSG00000020566 [Q99L60-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68775

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68775

UCSC genome browser

More...
UCSCi
uc007ncq.1, mouse [Q99L60-1]
uc007ncs.2, mouse [Q99L60-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB088357 mRNA Translation: BAC57950.1
BC003810 mRNA Translation: AAH03810.1
BC056636 mRNA Translation: AAH56636.1
CCDSiCCDS25827.1 [Q99L60-1]
CCDS49034.1 [Q99L60-2]
RefSeqiNP_001153104.1, NM_001159632.1 [Q99L60-2]
NP_598460.1, NM_133699.2 [Q99L60-1]
XP_006515259.1, XM_006515196.3 [Q99L60-2]
XP_006515262.1, XM_006515199.3 [Q99L60-3]

3D structure databases

SMRiQ99L60
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi213044, 1 interactor
STRINGi10090.ENSMUSP00000020884

Protein family/group databases

TCDBi3.A.2.2.6, the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

PTM databases

iPTMnetiQ99L60
PhosphoSitePlusiQ99L60

Proteomic databases

jPOSTiQ99L60
PaxDbiQ99L60
PRIDEiQ99L60
ProteomicsDBi297536 [Q99L60-1]
297537 [Q99L60-2]
297538 [Q99L60-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26729, 282 antibodies

The DNASU plasmid repository

More...
DNASUi
68775

Genome annotation databases

EnsembliENSMUST00000020884; ENSMUSP00000020884; ENSMUSG00000020566 [Q99L60-2]
ENSMUST00000095820; ENSMUSP00000093500; ENSMUSG00000020566 [Q99L60-1]
ENSMUST00000221129; ENSMUSP00000152515; ENSMUSG00000020566 [Q99L60-3]
GeneIDi68775
KEGGimmu:68775
UCSCiuc007ncq.1, mouse [Q99L60-1]
uc007ncs.2, mouse [Q99L60-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
245973
MGIiMGI:1916025, Atp6v1c2

Phylogenomic databases

eggNOGiKOG2909, Eukaryota
GeneTreeiENSGT00390000004263
InParanoidiQ99L60
OMAiKPSYVQW
OrthoDBi1016088at2759
PhylomeDBiQ99L60
TreeFamiTF314912

Enzyme and pathway databases

ReactomeiR-MMU-1222556, ROS and RNS production in phagocytes
R-MMU-77387, Insulin receptor recycling
R-MMU-917977, Transferrin endocytosis and recycling
R-MMU-9639288, Amino acids regulate mTORC1
R-MMU-983712, Ion channel transport

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
68775, 0 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Atp6v1c2, mouse

Protein Ontology

More...
PROi
PR:Q99L60
RNActiQ99L60, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000020566, Expressed in prostate gland and 111 other tissues
ExpressionAtlasiQ99L60, baseline and differential
GenevisibleiQ99L60, MM

Family and domain databases

CDDicd14785, V-ATPase_C, 1 hit
InterProiView protein in InterPro
IPR004907, ATPase_V1-cplx_csu
IPR036132, Vac_ATP_synth_c_sf
PANTHERiPTHR10137, PTHR10137, 1 hit
PfamiView protein in Pfam
PF03223, V-ATPase_C, 1 hit
SUPFAMiSSF118203, SSF118203, 2 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVATC2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99L60
Secondary accession number(s): Q6PHA4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: June 1, 2001
Last modified: June 2, 2021
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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