UniProtKB - Q99880 (H2B1L_HUMAN)
Histone H2B type 1-L
H2BC13
Functioni
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
GO - Molecular functioni
- DNA binding Source: GO_Central
- protein heterodimerization activity Source: InterPro
GO - Biological processi
- nucleosome assembly Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Enzyme and pathway databases
PathwayCommonsi | Q99880 |
Reactomei | R-HSA-110328, Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110329, Cleavage of the damaged pyrimidine R-HSA-110330, Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110331, Cleavage of the damaged purine R-HSA-1221632, Meiotic synapsis R-HSA-171306, Packaging Of Telomere Ends R-HSA-1912408, Pre-NOTCH Transcription and Translation R-HSA-201722, Formation of the beta-catenin:TCF transactivating complex R-HSA-212300, PRC2 methylates histones and DNA R-HSA-2299718, Condensation of Prophase Chromosomes R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559586, DNA Damage/Telomere Stress Induced Senescence R-HSA-3214815, HDACs deacetylate histones R-HSA-3214847, HATs acetylate histones R-HSA-427359, SIRT1 negatively regulates rRNA expression R-HSA-427389, ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427413, NoRC negatively regulates rRNA expression R-HSA-5250924, B-WICH complex positively regulates rRNA expression R-HSA-5334118, DNA methylation R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5689880, Ub-specific processing proteases R-HSA-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693571, Nonhomologous End-Joining (NHEJ) R-HSA-5693607, Processing of DNA double-strand break ends R-HSA-606279, Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-68616, Assembly of the ORC complex at the origin of replication R-HSA-69473, G2/M DNA damage checkpoint R-HSA-73728, RNA Polymerase I Promoter Opening R-HSA-73772, RNA Polymerase I Promoter Escape R-HSA-8866654, E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-9018519, Estrogen-dependent gene expression R-HSA-912446, Meiotic recombination R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9616222, Transcriptional regulation of granulopoiesis R-HSA-9670095, Inhibition of DNA recombination at telomere R-HSA-9710421, Defective pyroptosis R-HSA-977225, Amyloid fiber formation |
SignaLinki | Q99880 |
SIGNORi | Q99880 |
Names & Taxonomyi
Protein namesi | Recommended name: Histone H2B type 1-LAlternative name(s): Histone H2B.c Short name: H2B/c |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4748, H2BC13 |
MIMi | 602800, gene |
neXtProti | NX_Q99880 |
VEuPathDBi | HostDB:ENSG00000185130 |
Subcellular locationi
Nucleus
Other locations
Cytosol
- cytosol Source: HPA
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Other locations
- nucleosome Source: UniProtKB
Keywords - Cellular componenti
Chromosome, Nucleosome core, NucleusPathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000185130 |
PharmGKBi | PA29123 |
Miscellaneous databases
Pharosi | Q99880, Tdark |
Genetic variation databases
BioMutai | HIST1H2BL |
DMDMi | 7387743 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000071829 | 2 – 126 | Histone H2B type 1-LAdd BLAST | 125 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylprolineBy similarity | 1 | |
Modified residuei | 6 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-acetyllysine; alternateCombined sources2 Publications | 1 | |
Modified residuei | 6 | N6-butyryllysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 6 | N6-lactoyllysine; alternate1 Publication | 1 | |
Cross-linki | 6 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources | ||
Modified residuei | 7 | ADP-ribosylserine1 Publication | 1 | |
Modified residuei | 12 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-acetyllysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 12 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 13 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 13 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 13 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 15 | Phosphoserine; by STK4/MST11 Publication | 1 | |
Modified residuei | 16 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 16 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 16 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-acetyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 17 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-acetyllysine; alternate2 Publications | 1 | |
Modified residuei | 21 | N6-butyryllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 21 | N6-lactoyllysine; alternate1 Publication | 1 | |
Cross-linki | 21 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity | ||
Modified residuei | 24 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 24 | N6-acetyllysine; alternateBy similarity | 1 | |
Modified residuei | 24 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 24 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 25 | N6-(2-hydroxyisobutyryl)lysine1 Publication | 1 | |
Modified residuei | 35 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-crotonyllysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 35 | N6-succinyllysine; alternate1 Publication | 1 | |
Cross-linki | 35 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate1 Publication | ||
Modified residuei | 37 | Phosphoserine; by AMPKBy similarity | 1 | |
Modified residuei | 44 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 44 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 44 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 47 | N6-methyllysine; alternate1 Publication | 1 | |
Modified residuei | 58 | N6,N6-dimethyllysine; alternate1 Publication | 1 | |
Modified residuei | 58 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 80 | Dimethylated arginineBy similarity | 1 | |
Modified residuei | 86 | N6,N6,N6-trimethyllysine; alternateBy similarity | 1 | |
Modified residuei | 86 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 86 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 86 | N6-acetyllysine; alternateBy similarity | 1 | |
Modified residuei | 86 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 87 | Omega-N-methylarginineBy similarity | 1 | |
Modified residuei | 93 | Omega-N-methylarginineBy similarity | 1 | |
Modified residuei | 109 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 109 | N6-methyllysine; alternate1 Publication | 1 | |
Glycosylationi | 113 | O-linked (GlcNAc) serineBy similarity | 1 | |
Modified residuei | 116 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 117 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-malonyllysine; alternate1 Publication | 1 | |
Modified residuei | 117 | N6-methylated lysine; alternateBy similarity | 1 | |
Modified residuei | 117 | N6-succinyllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-(2-hydroxyisobutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-(beta-hydroxybutyryl)lysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-glutaryllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-lactoyllysine; alternate1 Publication | 1 | |
Modified residuei | 121 | N6-succinyllysine; alternate1 Publication | 1 | |
Cross-linki | 121 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate3 Publications |
Post-translational modificationi
Keywords - PTMi
Acetylation, ADP-ribosylation, Glycoprotein, Hydroxylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q99880 |
jPOSTi | Q99880 |
MassIVEi | Q99880 |
MaxQBi | Q99880 |
PaxDbi | Q99880 |
PeptideAtlasi | Q99880 |
PRIDEi | Q99880 |
ProteomicsDBi | 78517 |
TopDownProteomicsi | Q99880 |
2D gel databases
SWISS-2DPAGEi | P99060 |
PTM databases
GlyGeni | Q99880, 2 sites, 1 O-linked glycan (1 site) |
iPTMneti | Q99880 |
PhosphoSitePlusi | Q99880 |
SwissPalmi | Q99880 |
Expressioni
Gene expression databases
Bgeei | ENSG00000185130, Expressed in stomach and 91 other tissues |
Genevisiblei | Q99880, HS |
Organism-specific databases
HPAi | ENSG00000185130, Tissue enhanced (bone marrow, brain) |
Interactioni
Subunit structurei
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Binary interactionsi
GO - Molecular functioni
- protein heterodimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 113936, 80 interactors |
DIPi | DIP-38154N |
IntActi | Q99880, 51 interactors |
MINTi | Q99880 |
STRINGi | 9606.ENSP00000366618 |
Miscellaneous databases
RNActi | Q99880, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 36 | DisorderedSequence analysisAdd BLAST | 36 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 17 – 35 | Basic residuesSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1744, Eukaryota |
GeneTreei | ENSGT01030000234651 |
HOGENOMi | CLU_075666_2_1_1 |
InParanoidi | Q99880 |
OMAi | FERITME |
OrthoDBi | 1536672at2759 |
PhylomeDBi | Q99880 |
TreeFami | TF300212 |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
10 20 30 40 50
MPELAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH
60 70 80 90 100
PDTGISSKAM GIMNSFVNDI FERIASEASR LAHYNKRSTI TSREIQTAVR
110 120
LLLPGELAKH AVSEGTKAVT KYTSSK
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_049313 | 4 | L → P. Corresponds to variant dbSNP:rs200484Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z83740 Genomic DNA Translation: CAB06035.1 AF531295 Genomic DNA Translation: AAN06695.1 AK312114 mRNA Translation: BAG35050.1 AL009179 Genomic DNA No translation available. BC093759 mRNA No translation available. BC093761 mRNA No translation available. |
CCDSi | CCDS4625.1 |
RefSeqi | NP_003510.1, NM_003519.3 |
Genome annotation databases
Ensembli | ENST00000377401.4; ENSP00000366618.2; ENSG00000185130.6 |
GeneIDi | 8340 |
KEGGi | hsa:8340 |
MANE-Selecti | ENST00000377401.4; ENSP00000366618.2; NM_003519.4; NP_003510.1 |
UCSCi | uc003njl.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z83740 Genomic DNA Translation: CAB06035.1 AF531295 Genomic DNA Translation: AAN06695.1 AK312114 mRNA Translation: BAG35050.1 AL009179 Genomic DNA No translation available. BC093759 mRNA No translation available. BC093761 mRNA No translation available. |
CCDSi | CCDS4625.1 |
RefSeqi | NP_003510.1, NM_003519.3 |
3D structure databases
AlphaFoldDBi | Q99880 |
SMRi | Q99880 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 113936, 80 interactors |
DIPi | DIP-38154N |
IntActi | Q99880, 51 interactors |
MINTi | Q99880 |
STRINGi | 9606.ENSP00000366618 |
PTM databases
GlyGeni | Q99880, 2 sites, 1 O-linked glycan (1 site) |
iPTMneti | Q99880 |
PhosphoSitePlusi | Q99880 |
SwissPalmi | Q99880 |
Genetic variation databases
BioMutai | HIST1H2BL |
DMDMi | 7387743 |
2D gel databases
SWISS-2DPAGEi | P99060 |
Proteomic databases
EPDi | Q99880 |
jPOSTi | Q99880 |
MassIVEi | Q99880 |
MaxQBi | Q99880 |
PaxDbi | Q99880 |
PeptideAtlasi | Q99880 |
PRIDEi | Q99880 |
ProteomicsDBi | 78517 |
TopDownProteomicsi | Q99880 |
Protocols and materials databases
Antibodypediai | 67730, 54 antibodies from 9 providers |
DNASUi | 8340 |
Genome annotation databases
Ensembli | ENST00000377401.4; ENSP00000366618.2; ENSG00000185130.6 |
GeneIDi | 8340 |
KEGGi | hsa:8340 |
MANE-Selecti | ENST00000377401.4; ENSP00000366618.2; NM_003519.4; NP_003510.1 |
UCSCi | uc003njl.4, human |
Organism-specific databases
CTDi | 8340 |
GeneCardsi | H2BC13 |
HGNCi | HGNC:4748, H2BC13 |
HPAi | ENSG00000185130, Tissue enhanced (bone marrow, brain) |
MIMi | 602800, gene |
neXtProti | NX_Q99880 |
OpenTargetsi | ENSG00000185130 |
PharmGKBi | PA29123 |
VEuPathDBi | HostDB:ENSG00000185130 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1744, Eukaryota |
GeneTreei | ENSGT01030000234651 |
HOGENOMi | CLU_075666_2_1_1 |
InParanoidi | Q99880 |
OMAi | FERITME |
OrthoDBi | 1536672at2759 |
PhylomeDBi | Q99880 |
TreeFami | TF300212 |
Enzyme and pathway databases
PathwayCommonsi | Q99880 |
Reactomei | R-HSA-110328, Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110329, Cleavage of the damaged pyrimidine R-HSA-110330, Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110331, Cleavage of the damaged purine R-HSA-1221632, Meiotic synapsis R-HSA-171306, Packaging Of Telomere Ends R-HSA-1912408, Pre-NOTCH Transcription and Translation R-HSA-201722, Formation of the beta-catenin:TCF transactivating complex R-HSA-212300, PRC2 methylates histones and DNA R-HSA-2299718, Condensation of Prophase Chromosomes R-HSA-2559580, Oxidative Stress Induced Senescence R-HSA-2559582, Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559586, DNA Damage/Telomere Stress Induced Senescence R-HSA-3214815, HDACs deacetylate histones R-HSA-3214847, HATs acetylate histones R-HSA-427359, SIRT1 negatively regulates rRNA expression R-HSA-427389, ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427413, NoRC negatively regulates rRNA expression R-HSA-5250924, B-WICH complex positively regulates rRNA expression R-HSA-5334118, DNA methylation R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5625886, Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5689880, Ub-specific processing proteases R-HSA-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693571, Nonhomologous End-Joining (NHEJ) R-HSA-5693607, Processing of DNA double-strand break ends R-HSA-606279, Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-68616, Assembly of the ORC complex at the origin of replication R-HSA-69473, G2/M DNA damage checkpoint R-HSA-73728, RNA Polymerase I Promoter Opening R-HSA-73772, RNA Polymerase I Promoter Escape R-HSA-8866654, E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-9018519, Estrogen-dependent gene expression R-HSA-912446, Meiotic recombination R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9616222, Transcriptional regulation of granulopoiesis R-HSA-9670095, Inhibition of DNA recombination at telomere R-HSA-9710421, Defective pyroptosis R-HSA-977225, Amyloid fiber formation |
SignaLinki | Q99880 |
SIGNORi | Q99880 |
Miscellaneous databases
BioGRID-ORCSi | 8340, 648 hits in 1012 CRISPR screens |
GeneWikii | HIST1H2BL |
GenomeRNAii | 8340 |
Pharosi | Q99880, Tdark |
PROi | PR:Q99880 |
RNActi | Q99880, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000185130, Expressed in stomach and 91 other tissues |
Genevisiblei | Q99880, HS |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H2B1L_HUMAN | |
Accessioni | Q99880Primary (citable) accession number: Q99880 Secondary accession number(s): B2R5A3, Q52LW9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 201 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families