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UniProtKB - Q99865 (SPI2A_HUMAN)

Entry version 154 (10 Feb 2021)
Sequence version 3 (17 Oct 2006)
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Protein

Spindlin-2A

Gene

SPIN2A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the regulation of cell cycle progression (By similarity). Exhibits H3K4me3-binding activity (PubMed:29061846).By similarity1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei169Histone H3K4me3 and H3R8me2aBy similarity1
Binding sitei176Histone H3K4me3 and H3R8me2aBy similarity1
Binding sitei180Histone H3K4me3 and H3R8me2aBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q99865

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spindlin-2A
Alternative name(s):
Protein DXF34
Spindlin-like protein 2A
Short name:
SPIN-2
Short name:
SPIN-2A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPIN2A
Synonyms:DXF34, SPIN2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20694, SPIN2A

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300621, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q99865

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000147059.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54466

Open Targets

More...OpenTargetsi		ENSG00000147059

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA144596490

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q99865, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SPIN2A

Domain mapping of disease mutations (DMDM)

More...DMDMi		116242797

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001813711 – 258Spindlin-2AAdd BLAST258

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q99865

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q99865

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q99865

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q99865

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q99865

PeptideAtlas

More...PeptideAtlasi		Q99865

PRoteomics IDEntifications database

More...PRIDEi		Q99865

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78507

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q99865

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q99865

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000147059, Expressed in sural nerve and 109 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q99865, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q99865, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000147059, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with C11orf84/SPINDOC (PubMed:29061846).

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119972, 8 interactors

Protein interaction database and analysis system

More...IntActi		Q99865, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000364043

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q99865, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q99865

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni50 – 99Tudor-like domain 1Sequence analysisAdd BLAST50
Regioni129 – 178Tudor-like domain 2Sequence analysisAdd BLAST50
Regioni138Histone H3K4me3 and H3R8me2a bindingBy similarity1
Regioni210 – 255Tudor-like domain 3Sequence analysisAdd BLAST46
Regioni246 – 248Histone H3K4me3 and H3R8me2a bindingBy similarity3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPIN/STSY family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QRYD, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182925

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_068595_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q99865

Identification of Orthologs from Complete Genome Data

More...OMAi		HHTISTN

Database of Orthologous Groups

More...OrthoDBi		1027563at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q99865

TreeFam database of animal gene trees

More...TreeFami		TF332665

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.80.10.70, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029564, SPIN-2
IPR003671, SPIN/Ssty
IPR042567, SPIN/Ssty_sf

The PANTHER Classification System

More...PANTHERi		PTHR10405, PTHR10405, 1 hit
PTHR10405:SF13, PTHR10405:SF13, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02513, Spin-Ssty, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q99865-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTPNAQEAE GQQTRAAAGR ATGSANMTKK KVSQKKQRGR PSSQPRRNIV 
        60         70         80         90        100
GCRISHGWKE GDEPITQWKG TVLDQVPINP SLYLVKYDGI DCVYGLELHR 
       110        120        130        140        150
DERVLSLKIL SDRVASSHIS DANLANTIIG KAVEHMFEGE HGSKDEWRGM 
       160        170        180        190        200
VLAQAPIMKA WFYITYEKDP VLYMYQLLDD YKEGDLRIMP ESSESPPTER 
       210        220        230        240        250
EPGGVVDGLI GKHVEYTKED GSKRIGMVIH QVETKPSVYF IKFDDDFHIY 

VYDLVKKS
Length:258
Mass (Da):29,188
Last modified:October 17, 2006 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDE860789970B4BCD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X074A0A087X074_HUMAN
Spindlin-2A
SPIN2A
157Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA70988 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti46R → C in CAA70988 (PubMed:9271673).Curated1
Sequence conflicti46R → C in AAH71694 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y09858 mRNA Translation: CAA70988.1 Frameshift.
AL022157 Genomic DNA No translation available.
BC071694 mRNA Translation: AAH71694.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS35312.1

NCBI Reference Sequences

More...RefSeqi		NP_061876.3, NM_019003.3
XP_005262073.3, XM_005262016.4
XP_005262074.3, XM_005262017.4
XP_005262076.1, XM_005262019.3
XP_016885087.1, XM_017029598.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000374906; ENSP00000364041; ENSG00000147059
ENST00000374908; ENSP00000364043; ENSG00000147059

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54466

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54466

UCSC genome browser

More...UCSCi		uc004dvb.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09858 mRNA Translation: CAA70988.1 Frameshift.
AL022157 Genomic DNA No translation available.
BC071694 mRNA Translation: AAH71694.1
CCDSiCCDS35312.1
RefSeqiNP_061876.3, NM_019003.3
XP_005262073.3, XM_005262016.4
XP_005262074.3, XM_005262017.4
XP_005262076.1, XM_005262019.3
XP_016885087.1, XM_017029598.1

3D structure databases

SMRiQ99865
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119972, 8 interactors
IntActiQ99865, 1 interactor
STRINGi9606.ENSP00000364043

PTM databases

iPTMnetiQ99865
PhosphoSitePlusiQ99865

Genetic variation databases

BioMutaiSPIN2A
DMDMi116242797

Proteomic databases

EPDiQ99865
jPOSTiQ99865
MassIVEiQ99865
MaxQBiQ99865
PaxDbiQ99865
PeptideAtlasiQ99865
PRIDEiQ99865
ProteomicsDBi78507

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		55479, 52 antibodies

The DNASU plasmid repository

More...DNASUi		54466

Genome annotation databases

EnsembliENST00000374906; ENSP00000364041; ENSG00000147059
ENST00000374908; ENSP00000364043; ENSG00000147059
GeneIDi54466
KEGGihsa:54466
UCSCiuc004dvb.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54466
DisGeNETi54466

GeneCards: human genes, protein and diseases

More...GeneCardsi		SPIN2A
HGNCiHGNC:20694, SPIN2A
HPAiENSG00000147059, Low tissue specificity
MIMi300621, gene
neXtProtiNX_Q99865
OpenTargetsiENSG00000147059
PharmGKBiPA144596490
VEuPathDBiHostDB:ENSG00000147059.8

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QRYD, Eukaryota
GeneTreeiENSGT00950000182925
HOGENOMiCLU_068595_0_0_1
InParanoidiQ99865
OMAiHHTISTN
OrthoDBi1027563at2759
PhylomeDBiQ99865
TreeFamiTF332665

Enzyme and pathway databases

PathwayCommonsiQ99865

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54466, 25 hits in 467 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54466
PharosiQ99865, Tdark

Protein Ontology

More...PROi		PR:Q99865
RNActiQ99865, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000147059, Expressed in sural nerve and 109 other tissues
ExpressionAtlasiQ99865, baseline and differential
GenevisibleiQ99865, HS

Family and domain databases

Gene3Di2.80.10.70, 1 hit
InterProiView protein in InterPro
IPR029564, SPIN-2
IPR003671, SPIN/Ssty
IPR042567, SPIN/Ssty_sf
PANTHERiPTHR10405, PTHR10405, 1 hit
PTHR10405:SF13, PTHR10405:SF13, 1 hit
PfamiView protein in Pfam
PF02513, Spin-Ssty, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPI2A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99865
Secondary accession number(s): O75650, Q6IPW2, Q9UJJ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: October 17, 2006
Last modified: February 10, 2021
This is version 154 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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