Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 229  Show
  1. 1
    "Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase."
    Wang X.S., Diener K., Jannuzzi D., Trollinger D., Tan T.-H., Lichenstein H., Zukowski M., Yao Z.
    J. Biol. Chem. 271:31607-31611(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION.
    Category: Function, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways."
    Ichijo H., Nishida E., Irie K., ten Dijke P., Saitoh M., Moriguchi T., Takagi M., Matsumoto K., Miyazono K., Gotoh Y.
    Science 275:90-94(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION.
    Category: Function, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 2 other entries.

  3. 3
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Tissue: Amygdala.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12931 other entries.

  4. 4
    "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3735 other entries.

  5. 5
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Eye and Lung.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50469 other entries.

  6. 6
    "Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1."
    Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., Ichijo H.
    EMBO J. 17:2596-2606(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH TXN, ACTIVITY REGULATION, FUNCTION.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 3 other entries.

  7. 7
    Cited for: ACTIVITY REGULATION, INTERACTION WITH TRAF2, FUNCTION.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  8. 8
    "Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx."
    Chang H.Y., Nishitoh H., Yang X., Ichijo H., Baltimore D.
    Science 281:1860-1863(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DAXX, MUTAGENESIS OF LYS-709.
    Category: Pathology & Biotech, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins."
    Zhang L., Chen J., Fu H.
    Proc. Natl. Acad. Sci. U.S.A. 96:8511-8515(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH 14-3-3 PROTEINS, ACTIVITY REGULATION, MUTAGENESIS OF SER-966, FUNCTION.
    Category: Function, Pathology & Biotech, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).
  10. 10
    "Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation."
    Hatai T., Matsuzawa A., Inoshita S., Mochida Y., Kuroda T., Sakamaki K., Kuida K., Yonehara S., Ichijo H., Takeda K.
    J. Biol. Chem. 275:26576-26581(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN APOPTOSIS.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin."
    Liu H., Nishitoh H., Ichijo H., Kyriakis J.M.
    Mol. Cell. Biol. 20:2198-2208(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT, INTERACTION WITH TRAF2, ACTIVITY REGULATION, FUNCTION.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).
  12. 12
    "Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3."
    McDonald P.H., Chow C.W., Miller W.E., Laporte S.A., Field M.E., Lin F.-T., Davis R.J., Lefkowitz R.J.
    Science 290:1574-1577(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ARRB2.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 other entries.

  13. 13
    "Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress."
    Morita K., Saitoh M., Tobiume K., Matsuura H., Enomoto S., Nishitoh H., Ichijo H.
    EMBO J. 20:6028-6036(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PPP5C, DEPHOSPHORYLATION AT THR-838, SUBCELLULAR LOCATION, ACTIVITY REGULATION, FUNCTION.
    Category: Function, Subcellular Location, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  14. 14
    "Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation."
    Sayama K., Hanakawa Y., Shirakata Y., Yamasaki K., Sawada Y., Sun L., Yamanishi K., Ichijo H., Hashimoto K.
    J. Biol. Chem. 276:999-1004(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN KERATINOCYTE DIFFERENTIATION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  15. 15
    "Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1."
    Kim A.H., Khursigara G., Sun X., Franke T.F., Chao M.V.
    Mol. Cell. Biol. 21:893-901(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-83, ACTIVITY REGULATION, FUNCTION.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 14 other entries.

  16. 16
    "HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell."
    Geleziunas R., Xu W., Takeda K., Ichijo H., Greene W.C.
    Nature 410:834-838(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH HIV-1 NEF (MICROBIAL INFECTION), INHIBITION BY HIV-1 NEF (MICROBIAL INFECTION).
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  17. 17
    "Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism."
    Chen J., Fujii K., Zhang L., Roberts T., Fu H.
    Proc. Natl. Acad. Sci. U.S.A. 98:7783-7788(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH RAF1.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  18. 18
    Cited for: INTERACTION WITH TRAF2 AND ERN1, ACTIVITY REGULATION, FUNCTION IN ER STRESS RESPONSE.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  19. 19
    "Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer."
    Tobiume K., Saitoh M., Ichijo H.
    J. Cell. Physiol. 191:95-104(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, HOMODIMERIZATION, ACTIVITY REGULATION, PHOSPHORYLATION AT THR-838.
    Category: Function, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  20. 20
    "Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)."
    Galvan V., Logvinova A., Sperandio S., Ichijo H., Bredesen D.E.
    J. Biol. Chem. 278:13325-13332(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH IGF1R, PHOSPHORYLATION, ACTIVITY REGULATION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 1 other entries.

  21. 21
    "AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance."
    Yuan Z.Q., Feldman R.I., Sussman G.E., Coppola D., Nicosia S.V., Cheng J.Q.
    J. Biol. Chem. 278:23432-23440(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-83, ACTIVITY REGULATION, FUNCTION.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).
  22. 22
    "AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3."
    Zhang R., He X., Liu W., Lu M., Hsieh J.-T., Min W.
    J. Clin. Invest. 111:1933-1943(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DAB2IP.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 5 other entries.

  23. 23
    "Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins."
    Subramanian R.R., Zhang H., Wang H., Ichijo H., Miyashita T., Fu H.
    Exp. Cell Res. 294:581-591(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH YWHAB; YWHAE; YWHAH; YWHAQ; YWHAZ AND SFN, FUNCTION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 5 other entries.

  24. 24
    "Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation."
    Goldman E.H., Chen L., Fu H.
    J. Biol. Chem. 279:10442-10449(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-966, ACTIVITY REGULATION, FUNCTION.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  25. 25
    "AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation."
    Zhang H., Zhang R., Luo Y., D'Alessio A., Pober J.S., Min W.
    J. Biol. Chem. 279:44955-44965(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DAB2IP.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 and mapped to 7 other entries.

1 to 25 of 229  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again