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UniProtKB - Q99598 (TSNAX_HUMAN)

Entry version 174 (12 Aug 2020)
Sequence version 1 (01 May 1997)
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Protein

Translin-associated protein X

Gene

TSNAX

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi129Magnesium1
Metal bindingi197Magnesium1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processDifferentiation, Spermatogenesis
LigandMagnesium, Metal-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q99598

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-426486, Small interfering RNA (siRNA) biogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Translin-associated protein X
Alternative name(s):
Translin-associated factor X
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TSNAX
Synonyms:TRAX
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000116918.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:12380, TSNAX

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		602964, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q99598

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		7257

Open Targets

More...OpenTargetsi		ENSG00000116918

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37048

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q99598, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TSNAX

Domain mapping of disease mutations (DMDM)

More...DMDMi		6136057

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001916861 – 290Translin-associated protein XAdd BLAST290

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki279Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Sumoylated with SUMO1.1 Publication

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q99598

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q99598

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q99598

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q99598

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q99598

PeptideAtlas

More...PeptideAtlasi		Q99598

PRoteomics IDEntifications database

More...PRIDEi		Q99598

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78351

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q99598

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q99598

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q99598

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000116918, Expressed in female gonad and 255 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q99598, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q99598, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000116918, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Ring-shaped heterooctamer of six TSN and two TSNAX subunits.

Interacts with GOLGA3, TSNAXIP1, SUN1 and AKAP9.

Interacts with the homodimeric form of C1D following gamma-radiation.

Interacts with TSN and C1D in a mutually exclusive manner.

5 Publications

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		113108, 108 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-890, C3PO endoribonuclease complex

Database of interacting proteins

More...DIPi		DIP-29463N

Molecular INTeraction database

More...MINTi		Q99598

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000355599

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q99598, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1290
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q99598

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni73 – 208Interaction with C1D1 PublicationAdd BLAST136

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the translin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3066, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153568

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_067225_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q99598

Identification of Orthologs from Complete Genome Data

More...OMAi		KAENVCY

Database of Orthologous Groups

More...OrthoDBi		1213910at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q99598

TreeFam database of animal gene trees

More...TreeFami		TF323633

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.58.190, 1 hit
1.20.58.200, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016069, Translin_C
IPR002848, Translin_fam
IPR016068, Translin_N
IPR036081, Translin_sf

The PANTHER Classification System

More...PANTHERi		PTHR10741, PTHR10741, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01997, Translin, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF74784, SSF74784, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q99598-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNKEGSGGF RKRKHDNFPH NQRREGKDVN SSSPVMLAFK SFQQELDARH 
        60         70         80         90        100
DKYERLVKLS RDITVESKRT IFLLHRITSA PDMEDILTES EIKLDGVRQK 
       110        120        130        140        150
IFQVAQELSG EDMHQFHRAI TTGLQEYVEA VSFQHFIKTR SLISMDEINK 
       160        170        180        190        200
QLIFTTEDNG KENKTPSSDA QDKQFGTWRL RVTPVDYLLG VADLTGELMR 
       210        220        230        240        250
MCINSVGNGD IDTPFEVSQF LRQVYDGFSF IGNTGPYEVS KKLYTLKQSL 
       260        270        280        290
AKVENACYAL KVRGSEIPKH MLADVFSVKT EMIDQEEGIS
Length:290
Mass (Da):33,112
Last modified:May 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD38B0DD96B50C0B9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5VVQ1Q5VVQ1_HUMAN
Translin-associated protein X
TSNAX
163Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X95073 mRNA Translation: CAA64469.1
AF271269, AF271267, AF271268 Genomic DNA Translation: AAK58640.1
AK313068 mRNA Translation: BAG35896.1
AL626763 Genomic DNA No translation available.
AL445524 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW69963.1
BC010376 mRNA Translation: AAH10376.1
BC011797 mRNA Translation: AAH11797.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1596.1

NCBI Reference Sequences

More...RefSeqi		NP_005990.1, NM_005999.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000366639; ENSP00000355599; ENSG00000116918

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7257

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7257

UCSC genome browser

More...UCSCi		uc001huw.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95073 mRNA Translation: CAA64469.1
AF271269, AF271267, AF271268 Genomic DNA Translation: AAK58640.1
AK313068 mRNA Translation: BAG35896.1
AL626763 Genomic DNA No translation available.
AL445524 Genomic DNA No translation available.
CH471098 Genomic DNA Translation: EAW69963.1
BC010376 mRNA Translation: AAH10376.1
BC011797 mRNA Translation: AAH11797.1
CCDSiCCDS1596.1
RefSeqiNP_005990.1, NM_005999.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3PJAX-ray3.00J/K/L1-290[»]
3QB5X-ray2.95K1-290[»]
SMRiQ99598
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi113108, 108 interactors
ComplexPortaliCPX-890, C3PO endoribonuclease complex
DIPiDIP-29463N
MINTiQ99598
STRINGi9606.ENSP00000355599

PTM databases

iPTMnetiQ99598
MetOSiteiQ99598
PhosphoSitePlusiQ99598

Polymorphism and mutation databases

BioMutaiTSNAX
DMDMi6136057

Proteomic databases

EPDiQ99598
jPOSTiQ99598
MassIVEiQ99598
MaxQBiQ99598
PaxDbiQ99598
PeptideAtlasiQ99598
PRIDEiQ99598
ProteomicsDBi78351

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		34686, 141 antibodies

The DNASU plasmid repository

More...DNASUi		7257

Genome annotation databases

EnsembliENST00000366639; ENSP00000355599; ENSG00000116918
GeneIDi7257
KEGGihsa:7257
UCSCiuc001huw.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7257
DisGeNETi7257
EuPathDBiHostDB:ENSG00000116918.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		TSNAX
HGNCiHGNC:12380, TSNAX
HPAiENSG00000116918, Low tissue specificity
MIMi602964, gene
neXtProtiNX_Q99598
OpenTargetsiENSG00000116918
PharmGKBiPA37048

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3066, Eukaryota
GeneTreeiENSGT00940000153568
HOGENOMiCLU_067225_1_0_1
InParanoidiQ99598
OMAiKAENVCY
OrthoDBi1213910at2759
PhylomeDBiQ99598
TreeFamiTF323633

Enzyme and pathway databases

PathwayCommonsiQ99598
ReactomeiR-HSA-426486, Small interfering RNA (siRNA) biogenesis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7257, 9 hits in 877 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		TSNAX

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7257
PharosiQ99598, Tbio

Protein Ontology

More...PROi		PR:Q99598
RNActiQ99598, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000116918, Expressed in female gonad and 255 other tissues
ExpressionAtlasiQ99598, baseline and differential
GenevisibleiQ99598, HS

Family and domain databases

Gene3Di1.20.58.190, 1 hit
1.20.58.200, 1 hit
InterProiView protein in InterPro
IPR016069, Translin_C
IPR002848, Translin_fam
IPR016068, Translin_N
IPR036081, Translin_sf
PANTHERiPTHR10741, PTHR10741, 1 hit
PfamiView protein in Pfam
PF01997, Translin, 1 hit
SUPFAMiSSF74784, SSF74784, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTSNAX_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99598
Secondary accession number(s): B1APC6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: May 1, 1997
Last modified: August 12, 2020
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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