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Protein

Protein S100-A13

Gene

S100A13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).By similarity2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi24 – 371Add BLAST14
Calcium bindingi64 – 752Add BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport
LigandCalcium, Copper, Lipid-binding, Metal-binding

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q99584

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein S100-A13
Alternative name(s):
S100 calcium-binding protein A13
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:S100A13
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000189171.14

Human Gene Nomenclature Database

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HGNCi
HGNC:10490 S100A13

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601989 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q99584

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6284

Open Targets

More...
OpenTargetsi
ENSG00000189171

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34902

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB01025 Amlexanox
DB00768 Olopatadine

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
S100A13

Domain mapping of disease mutations (DMDM)

More...
DMDMi
2493416

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001440191 – 98Protein S100-A13Add BLAST98

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei32PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q99584

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q99584

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q99584

PeptideAtlas

More...
PeptideAtlasi
Q99584

PRoteomics IDEntifications database

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PRIDEi
Q99584

ProteomicsDB human proteome resource

More...
ProteomicsDBi
78342

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q99584

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q99584

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q99584

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart and skeletal muscle.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000189171 Expressed in 109 organ(s), highest expression level in right lobe of thyroid gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_S100A13

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q99584 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB025494
HPA019592

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1 (By similarity).By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
PLEKHF2Q9H8W43EBI-721909,EBI-742388

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112192, 21 interactors

Protein interaction database and analysis system

More...
IntActi
Q99584, 9 interactors

Molecular INTeraction database

More...
MINTi
Q99584

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344822

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

198
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q99584

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q99584

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q99584

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 53EF-handAdd BLAST36

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the S-100 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IZIJ Eukaryota
ENOG410ZHGQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161854

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000246968

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG001479

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q99584

Identification of Orthologs from Complete Genome Data

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OMAi
LKFHEYW

Database of Orthologous Groups

More...
OrthoDBi
EOG091G103K

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q99584

TreeFam database of animal gene trees

More...
TreeFami
TF332727

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992 EF-hand-dom_pair
IPR013787 S100_Ca-bd_sub
IPR028487 S100A13

The PANTHER Classification System

More...
PANTHERi
PTHR11639:SF57 PTHR11639:SF57, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01023 S_100, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01394 S_100, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q99584-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAEPLTELE ESIETVVTTF FTFARQEGRK DSLSVNEFKE LVTQQLPHLL
60 70 80 90
KDVGSLDEKM KSLDVNQDSE LKFNEYWRLI GELAKEIRKK KDLKIRKK
Length:98
Mass (Da):11,471
Last modified:May 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1D1BE57F3CD49E81
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X99920 mRNA Translation: CAA68188.1
CR542149 mRNA Translation: CAG46946.1
BT006724 mRNA Translation: AAP35370.1
BX470102 Genomic DNA No translation available.
BC000632 mRNA Translation: AAH00632.1
BC068064 mRNA Translation: AAH68064.1
BC070291 mRNA Translation: AAH70291.1
AY987392 mRNA Translation: AAX89402.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30874.1

Protein sequence database of the Protein Information Resource

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PIRi
JC5064

NCBI Reference Sequences

More...
RefSeqi
NP_001019381.1, NM_001024210.1
NP_001019382.1, NM_001024211.1
NP_001019383.1, NM_001024212.1
NP_001019384.1, NM_001024213.1
NP_005970.1, NM_005979.2
XP_005245491.1, XM_005245434.3
XP_011508164.1, XM_011509862.2
XP_011508165.1, XM_011509863.2
XP_011508166.1, XM_011509864.1
XP_016857523.1, XM_017002034.1
XP_016857524.1, XM_017002035.1
XP_016857525.1, XM_017002036.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.516505

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000339556; ENSP00000344822; ENSG00000189171
ENST00000392622; ENSP00000376398; ENSG00000189171
ENST00000392623; ENSP00000376399; ENSG00000189171
ENST00000440685; ENSP00000392767; ENSG00000189171

Database of genes from NCBI RefSeq genomes

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GeneIDi
6284

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6284

UCSC genome browser

More...
UCSCi
uc001fcf.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X99920 mRNA Translation: CAA68188.1
CR542149 mRNA Translation: CAG46946.1
BT006724 mRNA Translation: AAP35370.1
BX470102 Genomic DNA No translation available.
BC000632 mRNA Translation: AAH00632.1
BC068064 mRNA Translation: AAH68064.1
BC070291 mRNA Translation: AAH70291.1
AY987392 mRNA Translation: AAX89402.1
CCDSiCCDS30874.1
PIRiJC5064
RefSeqiNP_001019381.1, NM_001024210.1
NP_001019382.1, NM_001024211.1
NP_001019383.1, NM_001024212.1
NP_001019384.1, NM_001024213.1
NP_005970.1, NM_005979.2
XP_005245491.1, XM_005245434.3
XP_011508164.1, XM_011509862.2
XP_011508165.1, XM_011509863.2
XP_011508166.1, XM_011509864.1
XP_016857523.1, XM_017002034.1
XP_016857524.1, XM_017002035.1
XP_016857525.1, XM_017002036.1
UniGeneiHs.516505

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YURNMR-A/B1-98[»]
1YUSNMR-A/B1-98[»]
1YUTNMR-A/B1-98[»]
1YUUNMR-A/B1-98[»]
2EGDX-ray1.80A/B1-98[»]
2H2KX-ray2.00A/B1-98[»]
2K8MNMR-B/C1-98[»]
2KI4NMR-B/C1-98[»]
2KI6NMR-C/D1-98[»]
2KOTNMR-A/B1-98[»]
2L5XNMR-B/C1-98[»]
2LE9NMR-B/C2-98[»]
ProteinModelPortaliQ99584
SMRiQ99584
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112192, 21 interactors
IntActiQ99584, 9 interactors
MINTiQ99584
STRINGi9606.ENSP00000344822

Chemistry databases

DrugBankiDB01025 Amlexanox
DB00768 Olopatadine

PTM databases

iPTMnetiQ99584
PhosphoSitePlusiQ99584

Polymorphism and mutation databases

BioMutaiS100A13
DMDMi2493416

Proteomic databases

EPDiQ99584
MaxQBiQ99584
PaxDbiQ99584
PeptideAtlasiQ99584
PRIDEiQ99584
ProteomicsDBi78342
TopDownProteomicsiQ99584

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6284
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000339556; ENSP00000344822; ENSG00000189171
ENST00000392622; ENSP00000376398; ENSG00000189171
ENST00000392623; ENSP00000376399; ENSG00000189171
ENST00000440685; ENSP00000392767; ENSG00000189171
GeneIDi6284
KEGGihsa:6284
UCSCiuc001fcf.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6284
DisGeNETi6284
EuPathDBiHostDB:ENSG00000189171.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
S100A13
HGNCiHGNC:10490 S100A13
HPAiCAB025494
HPA019592
MIMi601989 gene
neXtProtiNX_Q99584
OpenTargetsiENSG00000189171
PharmGKBiPA34902

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IZIJ Eukaryota
ENOG410ZHGQ LUCA
GeneTreeiENSGT00940000161854
HOGENOMiHOG000246968
HOVERGENiHBG001479
InParanoidiQ99584
OMAiLKFHEYW
OrthoDBiEOG091G103K
PhylomeDBiQ99584
TreeFamiTF332727

Enzyme and pathway databases

SIGNORiQ99584

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
S100A13 human
EvolutionaryTraceiQ99584

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
S100A13

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6284

Protein Ontology

More...
PROi
PR:Q99584

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000189171 Expressed in 109 organ(s), highest expression level in right lobe of thyroid gland
CleanExiHS_S100A13
GenevisibleiQ99584 HS

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR013787 S100_Ca-bd_sub
IPR028487 S100A13
PANTHERiPTHR11639:SF57 PTHR11639:SF57, 1 hit
PfamiView protein in Pfam
PF01023 S_100, 1 hit
SMARTiView protein in SMART
SM01394 S_100, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS10AD_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99584
Secondary accession number(s): Q52PI9, Q6FGF8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 1, 1997
Last modified: December 5, 2018
This is version 166 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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