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Protein

Protein B2

Gene

B2

Organism
Boolarra virus (BoV)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Binds double-strand RNA (dsRNA) with high affinity. Suppresses the host RNA silencing-based antiviral response (By similarity).By similarity

Miscellaneous

Encoded on a subgenomic RNA (RNA3) synthesized during replication and which is co-terminal with RNA1.

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding, Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
Protein B2
Gene namesi
Name:B2
OrganismiBoolarra virus (BoV)
Taxonomic identifieri12286 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageNodaviridaeAlphanodavirus
Virus hostiHepialidae (ghost moths) [TaxID: 41021]
Proteomesi
  • UP000204043 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002236891 – 106Protein B2Add BLAST106

Expressioni

Developmental stagei

Expressed at high levels early in the viral replication cycle.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ992I9
SMRiQ992I9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 73RNA-bindingBy similarityAdd BLAST73

Domaini

The dsRNA-binding region is required for suppression of RNA silencing.By similarity

Sequence similaritiesi

Belongs to the nodaviridae B2 protein family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR024377 RNA-bd_B2
IPR037209 RNA-bd_B2_sf
PfamiView protein in Pfam
PF11473 B2, 1 hit
SUPFAMiSSF140506 SSF140506, 1 hit

Sequencei

Sequence statusi: Complete.

Q992I9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSKLALIQE LPDRIQKAVE VVLAMSYQEA PNNVRRDLDN LQACLNKAKQ
60 70 80 90 100
TVNRMVTSLL DKPSMAAYLE GKPLPEERPT LEERLRKLEL SREPPPTRSD

PAPAKL
Length:106
Mass (Da):12,004
Last modified:June 1, 2001 - v1
Checksum:i94E05B689304BCA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329080 Genomic RNA Translation: AAK15752.1
RefSeqiNP_689440.1, NC_004142.1

Genome annotation databases

GeneIDi956657
KEGGivg:956657

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329080 Genomic RNA Translation: AAK15752.1
RefSeqiNP_689440.1, NC_004142.1

3D structure databases

ProteinModelPortaliQ992I9
SMRiQ992I9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi956657
KEGGivg:956657

Family and domain databases

InterProiView protein in InterPro
IPR024377 RNA-bd_B2
IPR037209 RNA-bd_B2_sf
PfamiView protein in Pfam
PF11473 B2, 1 hit
SUPFAMiSSF140506 SSF140506, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB2_BOOLV
AccessioniPrimary (citable) accession number: Q992I9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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