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Entry version 119 (29 Sep 2021)
Sequence version 2 (09 Jan 2007)
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Protein

Chitin synthase 3

Gene

CHS3

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • chitin synthase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:MONOMER-17189

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.4.1.16, 6587

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT2, Glycosyltransferase Family 2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chitin synthase 3 (EC:2.4.1.16)
Alternative name(s):
Chitin synthase I
Chitin-UDP acetyl-glucosaminyl transferase 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHS3
Synonyms:CHS1
ORF Names:UMAG_10120
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237631 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaUstilaginomycetesUstilaginalesUstilaginaceaeUstilago
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000561 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:UMAG_10120

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei723 – 743HelicalSequence analysisAdd BLAST21
Transmembranei760 – 780HelicalSequence analysisAdd BLAST21
Transmembranei796 – 816HelicalSequence analysisAdd BLAST21
Transmembranei830 – 850HelicalSequence analysisAdd BLAST21
Transmembranei860 – 880HelicalSequence analysisAdd BLAST21
Transmembranei963 – 983HelicalSequence analysisAdd BLAST21
Transmembranei998 – 1018HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Cytoplasmic vesicle, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Miscellaneous databases

Pathogen-Host Interaction database

More...
PHI-basei
PHI:1110

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001937191 – 1029Chitin synthase 3Add BLAST1029

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi37N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi401N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi514N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi527N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi689N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5270.UM00474P0

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 29DisorderedSequence analysisAdd BLAST29
Regioni46 – 105DisorderedSequence analysisAdd BLAST60
Regioni168 – 209DisorderedSequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi46 – 64Polar residuesSequence analysisAdd BLAST19
Compositional biasi71 – 105Polar residuesSequence analysisAdd BLAST35
Compositional biasi169 – 200Basic and acidic residuesSequence analysisAdd BLAST32

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2571, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q99126

Identification of Orthologs from Complete Genome Data

More...
OMAi
LFSMGNK

Database of Orthologous Groups

More...
OrthoDBi
256142at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004835, Chitin_synth
IPR004834, Chitin_synth_fun
IPR013616, Chitin_synth_N
IPR029044, Nucleotide-diphossugar_trans

The PANTHER Classification System

More...
PANTHERi
PTHR22914, PTHR22914, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01644, Chitin_synth_1, 1 hit
PF08407, Chitin_synth_1N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448, SSF53448, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q99126-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAYYSRPASA GAARAQDDQD PYPYYPDPDL IVGSGANTSF VNPYEASGAA
60 70 80 90 100
SSASHTSPFS DAHAASASPA SILPLSHQQV SAHAPQQQHM SISVDPRDGQ
110 120 130 140 150
QSRMPGLSES FYSQAAYALA SPPPAAGALS PSAHLATLPE HSQAPLSGSV
160 170 180 190 200
DGEYTYYSQS AAGHYSSLAH RHGQDDEDDD DAETKYSPSS AHDEKYAYDR
210 220 230 240 250
PDSAAAGTSP FGRAAGIAYL QSPYAQVARN DDDDEDEDAE DPYRVLTRDS
260 270 280 290 300
AFGGDNGQGY DPNSAYGGAG MAGPTGQFGD NHFDTQHFGP APARGAQLRR
310 320 330 340 350
HKTKKNVRLT KGNLILDCPV PTKLQTFLTR RAEDEFTTMR YSAVTCDPDD
360 370 380 390 400
FASESFTLRP ALYGRHTELF IAITMYNEDE VLFCRTFHGV MKNIAHLCSR
410 420 430 440 450
NKSRTWGKDG WKKVVVAIIS DGRKKIHPRV LDCLAALGVY QDGVAKNMVD
460 470 480 490 500
GKEVRAHLYE YTTQLSIDSN LQFKGAERGL VPMQIIFCLK EKNAKKINSH
510 520 530 540 550
RWFFNAFCPI LQPNVTILLD VGTRPENKSI YYLWKSFDLN SNVAGACGEI
560 570 580 590 600
CAETKGKWGV GPLLLNPLVA AQNFEYKISN ILDKTTESVM GYISVLPGAF
610 620 630 640 650
SAYRYIALQN DEFGHGPLAS YFKGENLLGA DADVFTSNMY LAEDRILCFE
660 670 680 690 700
LAAKRGHGWV LKYVKSARGV TDVPEGLPEF ISQRRRWLNG SFFAAVYALY
710 720 730 740 750
HTAQFVRSGH NVWRKSLLVF ESFYSFVNMC FAWFGLANYY IFFRILTTSL
760 770 780 790 800
EDPTFKLRGI GVFNVFMQYI YLGTVVSSFI FAMGNRPQGS KWKYWAAVVV
810 820 830 840 850
FALLTVYMMV AAVLCLSKVV ARVEHDAIYA QMVVSLLATY GVYLISSLLA
860 870 880 890 900
CDPLHLITSF LQYLLLAPTY INILNIYAFC NLHDFSWGTK GDTSISADLG
910 920 930 940 950
AVVSTSKGTV EITLPTAQAD IDTAYDDALN NLRTRPMIIR GDASNAEKEA
960 970 980 990 1000
RQMDYYKNIR TNVVLAWALS NGVLAAFILN GDAAGTFSDT GGVTRTKVYM
1010 1020
VLVLIFVAGM ACIRFIGSTL YLTIRLING
Length:1,029
Mass (Da):113,242
Last modified:January 9, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73AFE99E52CF2F80
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA61027 differs from that shown. Internal deletion and contaminating sequence at the C-terminus from position 892 onwards.Curated
The sequence CAA61027 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8A → G in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti12 – 13AA → G in CAA61027 (PubMed:8932711).Curated2
Sequence conflicti29D → A in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti62A → E in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti121S → T in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti271 – 274MAGP → YGWT in CAA61027 (PubMed:8932711).Curated4
Sequence conflicti293A → R in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti312G → R in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti349 – 354DDFASE → TDLER in CAA61027 (PubMed:8932711).Curated6
Sequence conflicti520D → E in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti526 – 527EN → GD in CAA61027 (PubMed:8932711).Curated2
Sequence conflicti539L → V in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti545 – 546GA → AQ in CAA61027 (PubMed:8932711).Curated2
Sequence conflicti630A → R in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti692 – 747FFAAV…FRILT → SP in CAA61027 (PubMed:8932711).CuratedAdd BLAST56
Sequence conflicti882L → W in CAA61027 (PubMed:8932711).Curated1
Sequence conflicti885F → M in CAA61027 (PubMed:8932711).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CM003140 Genomic DNA Translation: KIS72052.1
X87748 Genomic DNA Translation: CAA61027.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...
PIRi
S55520

NCBI Reference Sequences

More...
RefSeqi
XP_011386676.1, XM_011388374.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
KIS72052; KIS72052; UMAG_10120

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23566189

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
uma:UMAG_10120

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM003140 Genomic DNA Translation: KIS72052.1
X87748 Genomic DNA Translation: CAA61027.1 Sequence problems.
PIRiS55520
RefSeqiXP_011386676.1, XM_011388374.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5270.UM00474P0

Protein family/group databases

CAZyiGT2, Glycosyltransferase Family 2

Genome annotation databases

EnsemblFungiiKIS72052; KIS72052; UMAG_10120
GeneIDi23566189
KEGGiuma:UMAG_10120

Organism-specific databases

VEuPathDBiFungiDB:UMAG_10120

Phylogenomic databases

eggNOGiKOG2571, Eukaryota
InParanoidiQ99126
OMAiLFSMGNK
OrthoDBi256142at2759

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-17189
BRENDAi2.4.1.16, 6587

Miscellaneous databases

PHI-baseiPHI:1110

Family and domain databases

InterProiView protein in InterPro
IPR004835, Chitin_synth
IPR004834, Chitin_synth_fun
IPR013616, Chitin_synth_N
IPR029044, Nucleotide-diphossugar_trans
PANTHERiPTHR22914, PTHR22914, 1 hit
PfamiView protein in Pfam
PF01644, Chitin_synth_1, 1 hit
PF08407, Chitin_synth_1N, 1 hit
SUPFAMiSSF53448, SSF53448, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHS3_USTMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q99126
Secondary accession number(s): A0A0D1CGJ4, Q4PHD9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 9, 2007
Last modified: September 29, 2021
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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