UniProtKB - Q99078 (FUZ7_USTMA)
Protein
Dual specificity protein kinase FUZ7
Gene
FUZ7
Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Functioni
Protein kinase that is necessary for a-locus-dependent processes, such as conjugation tube formation, filament formation, and maintenance of filamentous growth, and for a-locus-independent processes, such as tumor induction and teliospore germination.
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 138 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 231 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 115 – 123 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- MAP kinase kinase activity Source: GO_Central
- protein serine/threonine kinase activity Source: UniProtKB-KW
- protein tyrosine kinase activity Source: UniProtKB-KW
GO - Biological processi
- activation of MAPK activity Source: GO_Central
- pheromone response MAPK cascade Source: EnsemblFungi
- regulation of ascospore formation Source: EnsemblFungi
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BRENDAi | 2.7.12.2, 6587 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:FUZ7 ORF Names:UMAG_01514 |
Organismi | Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) |
Taxonomic identifieri | 237631 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Basidiomycota › Ustilaginomycotina › Ustilaginomycetes › Ustilaginales › Ustilaginaceae › Ustilago › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:UMAG_01514 |
Subcellular locationi
Other locations
- cell division site Source: EnsemblFungi
- cell tip Source: EnsemblFungi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000085955 | 1 – 435 | Dual specificity protein kinase FUZ7Add BLAST | 435 |
Keywords - PTMi
PhosphoproteinFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 109 – 417 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 309 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.Curated
Phylogenomic databases
eggNOGi | KOG0581, Eukaryota |
HOGENOMi | CLU_000288_63_23_1 |
InParanoidi | Q99078 |
OMAi | EAWASTF |
OrthoDBi | 688282at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
Q99078-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLSSGAGSSI RKKRNFKGLQ LAESPLASPV DASATTPSHK PGEGSAASNA
60 70 80 90 100
STIGKSSAVT PGGSLALPVK NGLDTEPNSG ANYHNKLTQQ LANLELGVEY
110 120 130 140 150
KLDLKNEDLK TLSELGAGNG GTVTKVLHEK SGTVMAKKVV FIDAKPSVRK
160 170 180 190 200
QILRELQILH ECNSPYIVSF YGAYLNEPHI CMCMEFMQKD SLDGIYKKYG
210 220 230 240 250
PISPEICGKI AVAVSHGLTY LYDVHRIIHR DVKPSNILVN GAGQIKICDF
260 270 280 290 300
GVSGELINSI ADTFVGTSTY MSPERIQGDQ YSVKSDVWSL GVSIIELALG
310 320 330 340 350
RFPFAENEED DDSDADNNYT NEDLAGTLSP TKPAPMISLG QNEKQRRRKS
360 370 380 390 400
KPAGVSLEGS SHQMSILDLL QHIVNEPPPK LPEGRFPKHM EEFVNLCLLK
410 420 430
DPAKRPTPKD LTKHQYVIDA DAAKVDLQAW ADGMK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 296 – 297 | EL → DV in AAA62242 (PubMed:7926737).Curated | 2 | |
Sequence conflicti | 356 | S → T in AAA62242 (PubMed:7926737).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U07801 Genomic DNA Translation: AAA62242.1 CM003142 Genomic DNA Translation: KIS70344.1 |
RefSeqi | XP_011387552.1, XM_011389250.1 |
Genome annotation databases
EnsemblFungii | KIS70344; KIS70344; UMAG_01514 |
GeneIDi | 23562500 |
KEGGi | uma:UMAG_01514 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U07801 Genomic DNA Translation: AAA62242.1 CM003142 Genomic DNA Translation: KIS70344.1 |
RefSeqi | XP_011387552.1, XM_011389250.1 |
3D structure databases
SMRi | Q99078 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 5270.UM01514P0 |
Genome annotation databases
EnsemblFungii | KIS70344; KIS70344; UMAG_01514 |
GeneIDi | 23562500 |
KEGGi | uma:UMAG_01514 |
Organism-specific databases
EuPathDBi | FungiDB:UMAG_01514 |
Phylogenomic databases
eggNOGi | KOG0581, Eukaryota |
HOGENOMi | CLU_000288_63_23_1 |
InParanoidi | Q99078 |
OMAi | EAWASTF |
OrthoDBi | 688282at2759 |
Enzyme and pathway databases
BRENDAi | 2.7.12.2, 6587 |
Miscellaneous databases
PHI-basei | PHI:2224 PHI:402 PHI:6068 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FUZ7_USTMA | |
Accessioni | Q99078Primary (citable) accession number: Q99078 Secondary accession number(s): A0A0D1E2E5, Q4PEE9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1999 |
Last sequence update: | January 9, 2007 | |
Last modified: | December 2, 2020 | |
This is version 131 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families