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Protein
Submitted name:

Kv1.4 potassium channel

Gene

kcna4

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Kv1.4 potassium channelImported
Gene namesi
Name:kcna4Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-866203 kcna4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Transmembranei502 – 523HelicalSequence analysisAdd BLAST22
Transmembranei563 – 584HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ98TW3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini178 – 272BTBInterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052230
KOiK04877

Family and domain databases

Gene3Di1.20.120.350, 1 hit
1.20.5.600, 1 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003972 K_chnl_volt-dep_Kv1
IPR020467 K_chnl_volt-dep_Kv1.4
IPR012897 K_chnl_volt-dep_Kv1.4_TID
IPR037065 K_chnl_volt-dep_Kv1.4_TID_sf
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PF07941 K_channel_TID, 1 hit
PRINTSiPR00169 KCHANNEL
PR01511 KV14CHANNEL
PR01491 KVCHANNEL
PR01496 SHAKERCHANEL
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

Q98TW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVAMVSADS SGCSNHLPYG YAQARARERE RQAHSRATAA AAASGEGGNS
60 70 80 90 100
GGGAGVNARR APQNQVPERQ EEKSSQKKKS ARRRYWPLSG CNRWRSRHNE
110 120 130 140 150
CSGGAGGRRA GGEDDGTFPS ELGLCGSEEM MLREEVAEED QKFYICEEDE
160 170 180 190 200
KEANSLHRRR SPTEDGYHPV YSEFECCERV VINVSGMRYE TQLKTLSQFP
210 220 230 240 250
ETLLGDPEKR TRYFDPLRNE YFFDRNRLSF DSILYYYQSG GRLKRPVNVP
260 270 280 290 300
FDIFSEEVKF YELGEEALLK YREDEGFVKE EEKQLPENEF KKQVWLLFEY
310 320 330 340 350
PESSGAARGI AIVSVLVILI SIVIFCLETL PEFRDDKDNL LSPLGMGDDD
360 370 380 390 400
GAGEDGEGGA YNATFLSTDS GHTAFNDPFF IVETVCIVWF SFEFAVRLFA
410 420 430 440 450
CPSKPEFFKN IMNIIDIVSI LPYFITLGTE PGQQHPPQQQ QHLALVTGQQ
460 470 480 490 500
LPQGTGQQQQ AMSFAILRII RLVRVFRIFK LSRHSKGLQI LGHTLRASMR
510 520 530 540 550
ELGLLILFLF IGVILFSSAV YFAEADEPTT HFQSIPDAFW WAVVTMTTVG
560 570 580 590 600
YGDMKPTTVG GKIVGSLCAI AGVLTIALPV PVIVSNFNYF YHRETDNEEQ
610 620 630 640 650
TQLTQSSSSC PYLPTNLLKK LRSSTSSSLQ DKSEYLEMEE GLKESLCVKD
660 670
KAIEGTGNGN ETIKYNCVSL KILETDV
Length:677
Mass (Da):75,958
Last modified:June 1, 2001 - v1
Checksum:i7AEC0A62499A0C8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF323750 mRNA Translation: AAK11603.1
RefSeqiNP_001082075.1, NM_001088606.1
UniGeneiXl.749

Genome annotation databases

GeneIDi398211
KEGGixla:398211

Similar proteinsi

Entry informationi

Entry nameiQ98TW3_XENLA
AccessioniPrimary (citable) accession number: Q98TW3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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