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Protein

Probable acetoacetate decarboxylase 1

Gene

adc1

Organism
Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.UniRule annotation

Catalytic activityi

Acetoacetate = acetone + CO2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei116Schiff-base intermediate with acetoacetateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionDecarboxylase, Lyase
LigandSchiff base

Enzyme and pathway databases

BioCyciMLOT266835:G1G20-4727-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acetoacetate decarboxylase 1UniRule annotation (EC:4.1.1.4UniRule annotation)
Short name:
AAD 1UniRule annotation
Short name:
ADC 1UniRule annotation
Gene namesi
Name:adc1UniRule annotation
Ordered Locus Names:mll5917
OrganismiMesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099))
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
Proteomesi
  • UP000000552 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002071061 – 247Probable acetoacetate decarboxylase 1Add BLAST247

Interactioni

Protein-protein interaction databases

STRINGi266835.mll5917

Structurei

3D structure databases

ProteinModelPortaliQ98AN6
SMRiQ98AN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ADC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107GD3 Bacteria
COG4689 LUCA
HOGENOMiHOG000063822
KOiK01574
OMAiCTPRICE
OrthoDBiPOG091H0QG4

Family and domain databases

Gene3Di2.40.400.10, 1 hit
HAMAPiMF_00597 ADC, 1 hit
InterProiView protein in InterPro
IPR010451 Acetoacetate_decarboxylase
IPR023653 Acetoacetate_decarboxylase_bac
IPR023375 ADC_dom_sf
PfamiView protein in Pfam
PF06314 ADC, 1 hit
SUPFAMiSSF160104 SSF160104, 1 hit

Sequencei

Sequence statusi: Complete.

Q98AN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHQDTVRGKA FAMPLISPAY PAGPYRFRNR EYLIITYRTD PQKLRDLVPE
60 70 80 90 100
PLQVCEPMVK FEFIRMPDST GFGDYTEGGQ VIPVSFYGRR GSYTHCMFLD
110 120 130 140 150
DHPPIAGGRE LWGFPKKLAS PTLRTETDTL VGTLDYGPVR VATGTMGYKH
160 170 180 190 200
RAADLASVRA SLAEPNFLLK IIPHVDGTPR ICELVEYHLE DVHLRGAWTG
210 220 230 240
PAALNLWSHA LAPVAELPVL EVVSAVHLVA DLTLALGKVV HDYLAKA
Length:247
Mass (Da):27,390
Last modified:October 1, 2001 - v1
Checksum:iC36298F3EA4DCC1C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti16I → T in CAD31314 (PubMed:12003951).Curated1
Sequence conflicti87Y → C in CAD31314 (PubMed:12003951).Curated1
Sequence conflicti192V → A in CAD31314 (PubMed:12003951).Curated1
Sequence conflicti245 – 246AK → PE in CAD31314 (PubMed:12003951).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL672114 Genomic DNA Translation: CAD31314.1
BA000012 Genomic DNA Translation: BAB52286.1
RefSeqiWP_010913619.1, NC_002678.2

Genome annotation databases

EnsemblBacteriaiBAB52286; BAB52286; BAB52286
KEGGimlo:mll5917
PATRICifig|266835.9.peg.4710

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL672114 Genomic DNA Translation: CAD31314.1
BA000012 Genomic DNA Translation: BAB52286.1
RefSeqiWP_010913619.1, NC_002678.2

3D structure databases

ProteinModelPortaliQ98AN6
SMRiQ98AN6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266835.mll5917

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB52286; BAB52286; BAB52286
KEGGimlo:mll5917
PATRICifig|266835.9.peg.4710

Phylogenomic databases

eggNOGiENOG4107GD3 Bacteria
COG4689 LUCA
HOGENOMiHOG000063822
KOiK01574
OMAiCTPRICE
OrthoDBiPOG091H0QG4

Enzyme and pathway databases

BioCyciMLOT266835:G1G20-4727-MONOMER

Family and domain databases

Gene3Di2.40.400.10, 1 hit
HAMAPiMF_00597 ADC, 1 hit
InterProiView protein in InterPro
IPR010451 Acetoacetate_decarboxylase
IPR023653 Acetoacetate_decarboxylase_bac
IPR023375 ADC_dom_sf
PfamiView protein in Pfam
PF06314 ADC, 1 hit
SUPFAMiSSF160104 SSF160104, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiADC1_RHILO
AccessioniPrimary (citable) accession number: Q98AN6
Secondary accession number(s): Q8KJA4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2001
Last modified: October 10, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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