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Protein

Protein MC007

Gene

MC007

Organism
Molluscum contagiosum virus subtype 1 (MOCV) (MCVI)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in the modulation of host cell cycle. Induces a cytoplasmic sequestration of host RB1 at the mitochondrial membrane.1 Publication

GO - Biological processi

  • modulation by virus of host cell cycle Source: UniProtKB

Keywordsi

Biological processHost-virus interaction, Modulation of host cell cycle by virus

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MC007
Gene namesi
Name:MC007
OrganismiMolluscum contagiosum virus subtype 1 (MOCV) (MCVI)
Taxonomic identifieri10280 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeMolluscipoxvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000869 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Host mitochondrion, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004448001 – 217Protein MC007Add BLAST217

Interactioni

Subunit structurei

Interacts with host RB1; this interaction induces the cytosolic sequestration of RB1.1 Publication

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi141 – 145LXCXE motif1 Publication5

Sequencei

Sequence statusi: Complete.

Q98178-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHAELAEVAA AVSAAACIVG LRHARPGCAR AFVAGALVSS VGYTCFPAIR
60 70 80 90 100
HCVHMAARYL SYLCFVRGGA TACVHSVADE AVQELVDSLH RVLAERDQCV
110 120 130 140 150
LGSVELVQGS EPLVLGLPQA PVLCVPEPSG AVDPECVEVD LYCHENLRYE
160 170 180 190 200
SDVSEDEDKD DACDEGISLA RQTLLDLLAC SEDASGFSPP EDSFSSLLET
210
GELYDEVLDA SLARAEA
Length:217
Mass (Da):22,983
Last modified:February 1, 1997 - v1
Checksum:i7A6909126B510098
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60315 Genomic DNA Translation: AAC55135.1
KY040275 Genomic DNA Translation: AQY16746.1
KY040276 Genomic DNA Translation: AQY16927.1
KY040277 Genomic DNA Translation: AQY17106.1
PIRiT30609
RefSeqiNP_043958.1, NC_001731.1

Genome annotation databases

GeneIDi1487028
KEGGivg:1487028

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60315 Genomic DNA Translation: AAC55135.1
KY040275 Genomic DNA Translation: AQY16746.1
KY040276 Genomic DNA Translation: AQY16927.1
KY040277 Genomic DNA Translation: AQY17106.1
PIRiT30609
RefSeqiNP_043958.1, NC_001731.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1487028
KEGGivg:1487028

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiMC007_MCV1
AccessioniPrimary (citable) accession number: Q98178
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 18, 2018
Last sequence update: February 1, 1997
Last modified: September 12, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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